Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0638 | 0.0183 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Echinococcus granulosus | acetylcholinesterase | 0.3774 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | carboxylesterase | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.3774 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0638 | 0.0183 | 0.0183 |
Schistosoma mansoni | acetylcholinesterase | 0.0638 | 0.0183 | 0.0183 |
Echinococcus granulosus | carboxylesterase 5A | 0.3774 | 1 | 1 |
Onchocerca volvulus | 0.0638 | 0.0183 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0638 | 0.0183 | 0.5 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0579 | 0 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0638 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0638 | 0.0183 | 0.5 | |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0579 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Brugia malayi | Carboxylesterase family protein | 0.3774 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0638 | 0.0183 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3774 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3774 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.3774 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Brugia malayi | Carboxylesterase family protein | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Schistosoma mansoni | gliotactin | 0.0638 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0638 | 0.0183 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0638 | 0.0183 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | carboxylesterase | 0.3774 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3774 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0638 | 0.0183 | 0.0183 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0579 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0579 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.3774 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0638 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0638 | 0.0183 | 0.5 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0638 | 0.0183 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Brugia malayi | Carboxylesterase family protein | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3774 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0638 | 0.0183 | 0.0183 |
Brugia malayi | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.0183 | 0.0183 |
Echinococcus granulosus | acetylcholinesterase | 0.3774 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0638 | 0.0183 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0638 | 0.0183 | 0.0183 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0638 | 0.0183 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.