Detailed information for compound 838845

Basic information

Technical information
  • TDR Targets ID: 838845
  • Name: 2-[(3,4-dimethoxyphenyl)sulfonyl-(4-methylphe nyl)amino]-N-methylacetamide
  • MW: 378.443 | Formula: C18H22N2O5S
  • H donors: 1 H acceptors: 3 LogP: 2.28 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC(=O)CN(S(=O)(=O)c1ccc(c(c1)OC)OC)c1ccc(cc1)C
  • InChi: 1S/C18H22N2O5S/c1-13-5-7-14(8-6-13)20(12-18(21)19-2)26(22,23)15-9-10-16(24-3)17(11-15)25-4/h5-11H,12H2,1-4H3,(H,19,21)
  • InChiKey: RLKGPEDISLVNJF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(3,4-dimethoxyphenyl)sulfonyl-(4-methylphenyl)amino]-N-methyl-acetamide
  • 2-[(3,4-dimethoxyphenyl)sulfonyl-(4-methylphenyl)amino]-N-methyl-ethanamide
  • Oprea1_429407
  • ZINC00817198
  • CBMicro_018024
  • BIM-0018178.P001
  • 2-[(3,4-Dimethoxy-benzenesulfonyl)-p-tolyl-amino]-N-methyl-acetamide
  • BAS 02182938
  • Oprea1_433084

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus insulin receptor 0.0457 0.2058 0.2031
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0122 0.0341 0.0329
Echinococcus granulosus calcium dependent protein kinase 0.007 0.0075 0.0041
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0117 0.0318 0.0318
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0135 0.0123
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0234 0.0918 0.0886
Brugia malayi Protein kinase domain containing protein 0.0088 0.017 0.017
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0272 0.0238
Trichomonas vaginalis STE family protein kinase 0.0094 0.0199 0.0187
Giardia lamblia Kinase, CMGC GSK 0.0138 0.0424 0.0412
Brugia malayi Protein kinase domain containing protein 0.0163 0.0553 0.0553
Echinococcus multilocularis serine threonine protein kinase 0.021 0.0792 0.0774
Trypanosoma brucei rac serine-threonine kinase, putative 0.0303 0.1268 0.1258
Echinococcus granulosus mitogen activated protein kinase 11 0.0299 0.1251 0.122
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0094 0.0198 0.0198
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0242 0.0956 0.0925
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0126 0.0363 0.0363
Loa Loa (eye worm) hypothetical protein 0.0058 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0076 0.0107 0.0107
Leishmania major protein kinase, putative 0.0164 0.0556 0.0544
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0138 0.0424 0.0391
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0097 0.0217 0.0204
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0062 0.0033 0.0033
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0174 0.0608 0.4898
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0127 0.037 0.0351
Loa Loa (eye worm) hypothetical protein 0.0124 0.0352 0.0352
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0411 0.1826 0.1797
Echinococcus granulosus tyrosine protein kinase Lyn 0.035 0.151 0.1481
Echinococcus multilocularis serine:threonine protein kinase N2 0.0168 0.0576 0.0557
Brugia malayi Furin-like cysteine rich region family protein 0.0624 0.2916 0.2916
Echinococcus granulosus dual specificity protein kinase clk2 0.0164 0.0556 0.0523
Echinococcus granulosus serine threonine protein kinase nrc 0.0167 0.0571 0.0539
Loa Loa (eye worm) hypothetical protein 0.0129 0.0379 0.0379
Giardia lamblia Kinase, CMGC CDK 0.0174 0.0608 0.0596
Echinococcus granulosus aurora kinase A 0.0155 0.0513 0.048
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0198 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Brugia malayi Protein kinase domain containing protein 0.0168 0.0576 0.0576
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Loa Loa (eye worm) hypothetical protein 0.0088 0.0166 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0122 0.0341 0.0329
Entamoeba histolytica PH domain containing protein kinase, putative 0.013 0.0381 0.0369
Loa Loa (eye worm) hypothetical protein 0.0115 0.0307 0.0307
Echinococcus granulosus roundabout 2 0.0137 0.0417 0.0384
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0192 0.0179
Brugia malayi Protein kinase domain containing protein 0.0174 0.0611 0.0611
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0187 0.0175
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0086 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0623 0.2912 0.2912
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.102 0.1009
Loa Loa (eye worm) TK protein kinase 0.0224 0.0868 0.0868
Loa Loa (eye worm) hypothetical protein 0.0086 0.0158 0.0158
Echinococcus multilocularis casein kinase I alpha 0.0117 0.0318 0.0299
Echinococcus multilocularis serine:threonine protein kinase 0.0123 0.0347 0.0328
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0322
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0164 0.0556 0.0544
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0081 0.0134 0.0115
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0197 0.0725 0.0725
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0122 0.0341 0.0329
Giardia lamblia Kinase, CAMK CAMKL 0.0097 0.0217 0.0204
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0204 0.0763 0.0763
Schistosoma mansoni tyrosine kinase 0.0368 0.1601 0.159
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0204 0.0762 0.0762
Trichomonas vaginalis AGC family protein kinase 0.0155 0.0513 0.0501
Leishmania major protein kinase, putative 0.0109 0.0277 0.0265
Echinococcus multilocularis Immunoglobulin 0.0088 0.0166 0.0146
Plasmodium falciparum calcium-dependent protein kinase 5 0.0109 0.0277 0.4442
Trypanosoma brucei cdc2-related kinase 3 0.0174 0.0608 0.0596
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0094 0.0199 0.0165
Brugia malayi putative serine/threonine kinase SADA gamma 0.0097 0.0217 0.0217
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0167 0.0571 0.9386
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0094 0.0199 0.0165
Echinococcus granulosus expressed protein 0.0091 0.0183 0.0149
Entamoeba histolytica p21-activated kinase 0.0102 0.0239 0.0227
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0214 0.0814 0.0814
Echinococcus multilocularis cyclin dependent kinase 0.0174 0.0608 0.059
Brugia malayi Protein kinase domain containing protein 0.0088 0.017 0.017
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0411 0.1826 0.1826
Brugia malayi probable protein kinase 0.0278 0.1143 0.1143
Brugia malayi Tyrosine-protein kinase abl-1 0.021 0.0793 0.0793
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0081 0.0134 0.0134
Schistosoma mansoni nephrin 0.0115 0.0305 0.0293
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0082 0.014 0.012
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0311 0.1309 0.1279
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0086 0.0158 0.0146
Loa Loa (eye worm) hypothetical protein 0.0147 0.0471 0.0471
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus granulosus casein kinase I delta 0.0117 0.0318 0.0285
Echinococcus granulosus c src tyrosine kinase 0.0128 0.0375 0.0341
Entamoeba histolytica protein kinase, putative 0.0089 0.0175 0.0163
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0109 0.0277 0.0243
Trypanosoma cruzi polo-like protein kinase, putative 0.2006 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0271 0.1104 0.1087
Brugia malayi Fibronectin type III domain containing protein 0.0095 0.0204 0.0204
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Schistosoma mansoni tyrosine kinase 0.0075 0.0099 0.0087
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0109 0.0277 0.0258
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0623 0.2912 0.2912
Trypanosoma brucei protein kinase, putative 0.0082 0.0135 0.0123
Echinococcus multilocularis casein kinase i 0.0117 0.0318 0.0299
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0155 0.0513 0.048
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0109 0.0277 0.0277
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0299 0.1251 0.124
Schistosoma mansoni titin 0.0066 0.0058 0.0045
Echinococcus granulosus cGMP dependent protein kinase 1 0.0144 0.0455 0.0422
Echinococcus multilocularis raf serine:threonine protein kinase 0.0078 0.0114 0.0095
Brugia malayi hypothetical protein 0.0095 0.0204 0.0204
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0144 0.0455 0.0436
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Giardia lamblia Kinase, AGC PKA 0.0167 0.0571 0.056
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0239 0.0941 0.091
Onchocerca volvulus Serine\/threonine kinase homolog 0.2006 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0341 0.0329
Trypanosoma brucei polo-like protein kinase 0.2006 1 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0204 0.0204
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0175 0.0611 0.06
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0245 0.0972 0.0955
Brugia malayi hypothetical protein 0.0088 0.017 0.017
Echinococcus granulosus cyclin dependent kinase 1 0.0174 0.0608 0.0575
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0082 0.0135 0.1011
Schistosoma mansoni ephrin receptor 0.0108 0.0272 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0217 0.0204
Brugia malayi Egg laying defective protein 4 0.0144 0.0455 0.0455
Entamoeba histolytica protein kinase, putative 0.0138 0.0424 0.0412
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.024 0.0945 0.0927
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0109 0.0277 0.0258
Echinococcus granulosus titin 0.0066 0.0058 0.0023
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0122 0.0341 0.2705
Echinococcus granulosus serine:threonine protein kinase PLK1 0.2006 1 1
Leishmania major protein kinase, putative 0.0093 0.0192 0.0179
Loa Loa (eye worm) AUR protein kinase 0.0155 0.0513 0.0513
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0135 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0187 0.0175
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0094 0.0198 0.0186
Brugia malayi protein kinase C3,putative 0.016 0.0537 0.0537
Schistosoma mansoni protein kinase 0.0452 0.2035 0.2025
Brugia malayi Protein kinase domain containing protein 0.0164 0.0556 0.0556
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0175 0.0163
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0308
Brugia malayi STE20-like kinase MST 0.027 0.11 0.11
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0109 0.0277 0.0243
Brugia malayi Protein kinase domain containing protein 0.0467 0.2113 0.2113
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0062 0.0033 0.0021
Giardia lamblia Kinase, CMGC MAPK 0.0092 0.0187 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Echinococcus granulosus nervana 2 0.0127 0.037 0.0336
Entamoeba histolytica PH domain containing protein kinase, putative 0.0175 0.0611 0.06
Entamoeba histolytica hypothetical protein 0.0391 0.1723 0.1713
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0456 0.0445
Entamoeba histolytica protein kinase, putative 0.0303 0.1268 0.1258
Echinococcus granulosus hypothetical protein 0.0124 0.0354 0.0321
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.035 0.1513 0.1513
Echinococcus granulosus dual specificity 0.0094 0.0198 0.0164
Loa Loa (eye worm) hypothetical protein 0.0182 0.0652 0.0652
Giardia lamblia Kinase, CDC7 0.0098 0.0219 0.0206
Giardia lamblia Kinase, NEK 0.0146 0.0463 0.0452
Echinococcus multilocularis growth factor receptor bound protein 2 0.0086 0.0158 0.0139
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0097 0.0217 0.0204
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0311 0.1309 0.1292
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0081 0.0134 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0885 0.0874
Schistosoma mansoni growth factor receptor-bound protein 0.0086 0.0158 0.0146
Trypanosoma cruzi casein kinase, putative 0.0117 0.0318 0.0306
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.089 0.0879
Echinococcus granulosus casein kinase I delta 0.0117 0.0318 0.0285
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0311 0.1309 0.1292
Entamoeba histolytica protein kinase, putative 0.0303 0.1268 0.1258
Schistosoma mansoni vam6/vps39 related 0.0115 0.0307 0.0295
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0167 0.0571 0.056
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0277 0.0265
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0383 0.1681 0.1652
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0164 0.0556 0.0556
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0175 0.0163
Brugia malayi ephrin receptor 1 precursor 0.0073 0.0093 0.0093
Brugia malayi casein kinase I 0.0117 0.0318 0.0318
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0109 0.0277 0.0243
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0089 0.0172 0.2685
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0175 0.0163
Schistosoma mansoni tyrosine kinase 0.0564 0.2606 0.2596
Echinococcus granulosus casein kinase I gamma 0.0163 0.0553 0.052
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0452 0.2035 0.2008
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0234 0.0918 0.09
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0343 0.1475 0.1475
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0081 0.0134 0.0122
Echinococcus multilocularis serine:threonine protein kinase N2 0.0134 0.0401 0.0383
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Echinococcus granulosus twitchin 0.0147 0.0468 0.0435
Toxoplasma gondii histone kinase SNF1, putative 0.0097 0.0217 0.1679
Plasmodium falciparum NIMA related kinase 1 0.0146 0.0463 0.7571
Entamoeba histolytica protein kinase domain containing protein 0.0155 0.0513 0.0501
Echinococcus granulosus casein kinase i 0.0117 0.0318 0.0285
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0123 0.0347 0.0347
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0138 0.0424 0.0424
Leishmania major protein kinase, putative 0.0164 0.0556 0.0544
Loa Loa (eye worm) hypothetical protein 0.0123 0.0345 0.0345
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0155 0.0513 0.0501
Entamoeba histolytica cell division protein kinase 2, putative 0.0174 0.0608 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.1826 0.1815
Brugia malayi Immunoglobulin I-set domain containing protein 0.0066 0.0058 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0945 0.0934
Echinococcus granulosus mitogen activated protein kinase 3 0.0092 0.0187 0.0153
Plasmodium falciparum serine/threonine protein kinase 0.0091 0.0183 0.287
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0058 0.0045
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0124 0.0352 0.0333
Loa Loa (eye worm) IKK protein kinase 0.1003 0.4856 0.4856
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0219 0.0206
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0097 0.0217 0.0217
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Giardia lamblia Kinase, CMGC CDK 0.0174 0.0608 0.0596
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0091 0.0183 0.0171
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0089 0.0175 0.0156
Plasmodium vivax casein kinase 1, putative 0.0117 0.0318 0.5135
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0097 0.0217 0.0204
Echinococcus granulosus serine:threonine protein kinase 0.0123 0.0347 0.0314
Schistosoma mansoni hypothetical protein 0.0105 0.0255 0.0243
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0155 0.0509 0.0491
Loa Loa (eye worm) hypothetical protein 0.0092 0.0188 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0513 0.0501
Echinococcus multilocularis tyrosine protein kinase HCK 0.0224 0.0868 0.085
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0091 0.0183 0.1406
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0322
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0155 0.0513 0.0501
Schistosoma mansoni protein kinase 0.0094 0.0199 0.0187
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0124 0.0352 0.0319
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0167 0.0571 0.9386
Echinococcus granulosus serine:threonine kinase SAD 1 0.0097 0.0217 0.0183
Onchocerca volvulus 0.0088 0.017 0.0116
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0094 0.0198 0.0198
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0122 0.0341 0.0329
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0155 0.0513 0.0501
Brugia malayi map kinase activated protein kinase protein 2 0.0411 0.1826 0.1826
Plasmodium falciparum protein serine/threonine kinase-1 0.0164 0.0556 0.9121
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0109 0.0277 0.2176
Echinococcus granulosus serine:threonine protein kinase N2 0.0301 0.126 0.123
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0062 0.0033 0.0033
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus granulosus cGMP dependent protein kinase 1 0.0144 0.0455 0.0422
Echinococcus multilocularis casein kinase I alpha 0.0117 0.0318 0.0299
Echinococcus granulosus tyrosine protein kinase Fyn 0.0311 0.1309 0.1279
Echinococcus granulosus protein kinase shaggy 0.0138 0.0424 0.0391
Echinococcus granulosus epidermal growth factor receptor 0.0624 0.2916 0.2892
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.1091 0.108
Echinococcus multilocularis dual specificity 0.0094 0.0198 0.0179
Plasmodium falciparum calcium-dependent protein kinase 2 0.0109 0.0277 0.4442
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0341 0.0329
Echinococcus granulosus tyrosine protein kinase Fyn 0.0311 0.1309 0.1279
Echinococcus granulosus serine:threonine protein kinase N2 0.0134 0.0401 0.0368
Echinococcus granulosus dual specificity 0.0131 0.039 0.0357
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0204 0.0762 0.0744
Loa Loa (eye worm) AUR protein kinase 0.0155 0.0513 0.0513
Brugia malayi Protein kinase domain containing protein 0.0976 0.4717 0.4717
Schistosoma mansoni tyrosine kinase 0.0256 0.1029 0.1017
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0228 0.0885 0.0853
Leishmania major protein kinase, putative 0.0082 0.0135 0.0123
Brugia malayi Protein kinase domain containing protein 0.0197 0.0727 0.0727
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0198 0.0186
Plasmodium vivax protein kinase, putative 0.0058 0.0013 0.0016
Trypanosoma cruzi cdc2-related kinase 3 0.0174 0.0608 0.0596
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Echinococcus multilocularis tyrosine protein kinase Abl 0.021 0.0793 0.0775
Schistosoma mansoni protein kinase 0.0117 0.0318 0.0306
Schistosoma mansoni protein kinase 0.0155 0.0513 0.0501
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0122 0.0341 0.5522
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0212 0.0804 0.0786
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0608 0.0596
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.024 0.0945 0.0914
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0174 0.0608 0.0596
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0204 0.0762 0.0762
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0299 0.1251 0.124
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0174 0.0608 0.0596
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0097 0.0217 0.0204
Brugia malayi Protein kinase domain containing protein 0.0174 0.0608 0.0608
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0094 0.0199 0.018
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0246 0.098 0.0949
Echinococcus multilocularis serine:threonine protein kinase 38 0.0168 0.0576 0.0557
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0088 0.0166 0.0153
Entamoeba histolytica protein kinase domain containing protein 0.0214 0.0814 0.0803
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Schistosoma mansoni nck2/grb4 0.0086 0.0158 0.0146
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.0183 0.0171
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.011 0.0278 0.0245
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0109 0.0277 0.0258
Echinococcus multilocularis cyclin dependent kinase 5 0.0174 0.0608 0.059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0652 0.3059 0.3059
Echinococcus multilocularis calcium activated potassium channel 0.0144 0.0456 0.0438
Onchocerca volvulus 0.0138 0.0424 0.0371
Brugia malayi Protein kinase domain containing protein 0.0091 0.0183 0.0183
Loa Loa (eye worm) AGC/AKT protein kinase 0.0303 0.1268 0.1268
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0093 0.0192 0.0179
Echinococcus granulosus tyrosine protein kinase Src64B 0.0311 0.1309 0.1279
Entamoeba histolytica protein kinase, putative 0.0111 0.0284 0.0272
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0094 0.0199 0.0165
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0109 0.0277 0.0265
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0278 0.114 0.114
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0144 0.0455 0.3641
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0146 0.0463 0.3708
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0192 0.0179
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0109 0.0277 0.0277
Echinococcus granulosus N chimaerin 0.0081 0.0134 0.01
Trichomonas vaginalis STE family protein kinase 0.0094 0.0199 0.0187
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0311 0.1309 0.1292
Onchocerca volvulus 0.05 0.2281 0.2239
Trypanosoma cruzi polo-like protein kinase, putative 0.2006 1 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0092 0.0187 0.0175
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.041 0.1818 0.1789
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0092 0.0187 0.0175
Echinococcus granulosus dual specificity 0.0094 0.0198 0.0164
Echinococcus granulosus Protein kinase C brain isozyme 0.0245 0.0972 0.0941
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0246 0.098 0.0963
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0217 0.0204
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.0175 0.0175
Onchocerca volvulus 0.0098 0.0219 0.0165
Echinococcus multilocularis expressed conserved protein 0.0144 0.0455 0.0436
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.2006 1 1
Trypanosoma brucei protein kinase, putative 0.0092 0.0187 0.0175
Entamoeba histolytica protein kinase, putative 0.0079 0.0124 0.0112
Schistosoma mansoni protein kinase 0.0278 0.1143 0.1132
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Schistosoma mansoni tyrosine kinase 0.041 0.1818 0.1807
Brugia malayi Temporarily assigned gene name protein 59 0.0133 0.0398 0.0398
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0131 0.039 0.0378
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0278 0.114 0.1122
Onchocerca volvulus 0.1003 0.4856 0.4828
Brugia malayi Protein kinase domain containing protein 0.0131 0.039 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0576 0.0564
Echinococcus granulosus serine:threonine protein kinase 3 0.027 0.11 0.107
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Entamoeba histolytica protein kinase, putative 0.0131 0.039 0.0378
Giardia lamblia Kinase, STE STE20 0.0093 0.0192 0.0179
Entamoeba histolytica protein kinase domain containing protein 0.0131 0.039 0.0378
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Echinococcus multilocularis tyrosine protein kinase Blk 0.0271 0.1104 0.1087
Echinococcus granulosus rho-associated protein kinase 1 0.034 0.1461 0.1431
Onchocerca volvulus 0.0115 0.0307 0.0253
Leishmania major protein kinase, putative 0.0155 0.0513 0.0501
Loa Loa (eye worm) TK/ROR protein kinase 0.0062 0.0035 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0155 0.0513 0.0501
Echinococcus granulosus serine/threonine protein kinase 0.0175 0.0611 0.0579
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0266 0.1079 0.1061
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0347 0.0335
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Echinococcus granulosus tyrosine protein kinase shark 0.0088 0.017 0.0136
Brugia malayi phosphoinositide-dependent protein kinase I 0.0089 0.0175 0.0175
Onchocerca volvulus 0.019 0.0692 0.064
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0383 0.1681 0.1664
Brugia malayi Protein kinase domain containing protein 0.0457 0.2058 0.2058
Schistosoma mansoni protein kinase 0.0383 0.1681 0.167
Onchocerca volvulus 0.0078 0.0117 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Echinococcus granulosus raf serine:threonine protein kinase 0.0078 0.0114 0.008
Echinococcus granulosus tyrosine protein kinase ABL1 0.0302 0.1265 0.1235
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Giardia lamblia Kinase, CK1 Casein kinase 0.0117 0.0318 0.0306
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0228 0.0887 0.087
Echinococcus multilocularis aurora kinase A 0.0155 0.0513 0.0494
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0122 0.0341 0.0329
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0187 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0455 0.0443
Onchocerca volvulus 0.0117 0.0318 0.0265
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0204 0.0762 0.073
Loa Loa (eye worm) hypothetical protein 0.0124 0.0354 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0033 0.0021
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0174 0.0608 0.0575
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0155 0.0509 0.0476
Schistosoma mansoni rap gtpase-activating protein 0.0115 0.0307 0.0295
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Brugia malayi Temporarily assigned gene name protein 59 0.0115 0.0307 0.0307
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0164 0.0556 0.4468
Echinococcus granulosus cyclin dependent kinase 5 0.0174 0.0608 0.0575
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0214 0.0814 0.0814
Loa Loa (eye worm) hypothetical protein 0.0115 0.0307 0.0307
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0343 0.1475 0.1475
Echinococcus multilocularis cyclin dependent kinase 1 0.0174 0.0608 0.059
Trichomonas vaginalis STE family protein kinase 0.0093 0.0192 0.0179
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0078 0.0119 0.0099
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0229 0.089 0.089
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0155 0.0513 0.0494
Loa Loa (eye worm) hypothetical protein 0.0148 0.0475 0.0475
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0092 0.0187 0.0175
Schistosoma mansoni protein kinase 0.0163 0.0553 0.0541
Brugia malayi Protein kinase domain containing protein 0.057 0.2637 0.2637
Schistosoma mansoni protein kinase 0.0452 0.2035 0.2025
Onchocerca volvulus 0.0088 0.017 0.0116
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0311 0.1309 0.1292
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0197 0.0725 0.0725
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Entamoeba histolytica protein kinase domain containing protein 0.0082 0.0135 0.0123
Echinococcus multilocularis Immunoglobulin 0.0088 0.0166 0.0146
Brugia malayi protein kinase C II. 0.0204 0.0763 0.0763
Schistosoma mansoni tyrosine kinase 0.0368 0.1601 0.159
Echinococcus multilocularis dual specificity 0.0094 0.0198 0.0179
Schistosoma mansoni protein kinase 0.0242 0.0956 0.0945
Schistosoma mansoni tyrosine kinase 0.0368 0.1601 0.159
Toxoplasma gondii AGC kinase 0.0295 0.1229 1
Echinococcus multilocularis nervana 2 0.0127 0.037 0.0351
Trichomonas vaginalis AGC family protein kinase 0.0155 0.0513 0.0501
Echinococcus granulosus tyrosine protein kinase Src42A 0.0228 0.0887 0.0856
Entamoeba histolytica protein kinase, putative 0.0094 0.0199 0.0187
Schistosoma mansoni tyrosine kinase 0.0311 0.1309 0.1298
Entamoeba histolytica PH domain containing protein kinase, putative 0.013 0.0381 0.0369
Echinococcus granulosus cyclin dependent kinase 0.0174 0.0608 0.0575
Echinococcus multilocularis tyrosine protein kinase shark 0.0088 0.017 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0304 0.0292
Loa Loa (eye worm) hypothetical protein 0.0066 0.0055 0.0055
Schistosoma mansoni tyrosine kinase 0.0128 0.0375 0.0363
Schistosoma mansoni adapter molecule crk 0.0086 0.0158 0.0146
Trypanosoma cruzi cdc2-related kinase 1 0.0174 0.0608 0.0596
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0452 0.2035 0.202
Entamoeba histolytica protein kinase, putative 0.0072 0.0084 0.0072
Trypanosoma cruzi Protein kinase B 0.0175 0.0611 0.06
Schistosoma mansoni tyrosine kinase 0.041 0.1818 0.1807
Onchocerca volvulus 0.0086 0.0157 0.0102
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.006 0.0027 0.0014
Loa Loa (eye worm) hypothetical protein 0.0122 0.0341 0.0341
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0163 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0105 0.0255 0.0255
Entamoeba histolytica protein kinase , putative 0.0155 0.0513 0.0501
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0081 0.0134 0.0122
Onchocerca volvulus 0.034 0.1461 0.1414
Echinococcus granulosus titin 0.0066 0.0058 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0189 0.0684 0.0672
Echinococcus granulosus cGMP dependent protein kinase 0.0144 0.0455 0.0422
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0234 0.0918 0.0918
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Onchocerca volvulus 0.0088 0.017 0.0116
Plasmodium falciparum calcium-dependent protein kinase 1 0.0109 0.0277 0.4442
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0115 0.0307 0.0295
Brugia malayi P38 map kinase family protein 2 0.0299 0.1251 0.1251
Schistosoma mansoni tyrosine kinase 0.0311 0.1309 0.1298
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0138 0.0424 0.3384
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.2006 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.039 0.0378
Echinococcus granulosus protein kinase 0.0163 0.0553 0.052
Echinococcus multilocularis tyrosine protein kinase Srms 0.0271 0.1104 0.1087
Entamoeba histolytica PH domain containing protein kinase, putative 0.0175 0.0611 0.06
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0515 0.2354 0.2328
Entamoeba histolytica protein kinase, putative 0.0295 0.1229 0.1218
Brugia malayi hypothetical protein 0.0234 0.0918 0.0918
Brugia malayi Cam kinase protein 1 0.0109 0.0277 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0455 0.0443
Schistosoma mansoni serine/threonine protein kinase 0.2006 1 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.0307 0.0307
Echinococcus multilocularis mitogen activated protein kinase 3 0.0092 0.0187 0.0167
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0115 0.0307 0.0273
Loa Loa (eye worm) hypothetical protein 0.019 0.0692 0.0692
Echinococcus multilocularis epidermal growth factor receptor 0.041 0.1818 0.1802
Echinococcus multilocularis serine:threonine protein kinase 0.0123 0.0347 0.0328
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0254 0.102 0.1002
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0308
Brugia malayi Serine/threonine-protein kinase SULU 0.0234 0.0918 0.0918
Trypanosoma cruzi aurora B kinase, putative 0.0155 0.0513 0.0501
Trypanosoma brucei casein kinase I, isoform 2 0.0117 0.0318 0.0306
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0091 0.0183 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0341 0.0329
Brugia malayi Stress-activated protein kinase jnk-1 0.0278 0.114 0.114
Onchocerca volvulus 0.0088 0.017 0.0116
Echinococcus multilocularis titin 0.0066 0.0058 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0576 0.0564
Echinococcus granulosus Immunoglobulin 0.0088 0.0166 0.0131
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0383 0.1681 0.1681
Loa Loa (eye worm) thyroid receptor interactor 0.0114 0.0301 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0918 0.0906
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0424 0.0412
Schistosoma mansoni protein kinase 0.0072 0.0084 0.0072
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0204 0.0762 0.0711
Echinococcus multilocularis protein tyrosine kinase 0.0564 0.2606 0.2591
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0092 0.0187 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0114 0.0102
Trichomonas vaginalis CK1 family protein kinase 0.0117 0.0318 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0885 0.0874
Entamoeba histolytica protein kinase, putative 0.0091 0.0183 0.0171
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0217 0.0204
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0109 0.0277 0.2176
Echinococcus granulosus activin receptor type 0.0082 0.0135 0.0101
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0976 0.4717 0.4717
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Loa Loa (eye worm) AGC/NDR protein kinase 0.0168 0.0576 0.0576
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0119 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.002 0.0007
Echinococcus granulosus Vam6:Vps39 protein 0.0115 0.0307 0.0273
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0299 0.1251 0.1251
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0456 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.126 0.1249
Trypanosoma cruzi p21-activated kinase 3, putative 0.0062 0.0033 0.0021
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0109 0.0277 0.4442
Loa Loa (eye worm) hypothetical protein 0.0088 0.017 0.017
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0164 0.0556 0.0544
Schistosoma mansoni ste20-related kinase 0.0217 0.0828 0.0816
Loa Loa (eye worm) protein kinase domain-containing protein 0.0163 0.0553 0.0553
Schistosoma mansoni vesicular amine transporter 0.0088 0.0166 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0611 0.0599
Echinococcus multilocularis mitogen activated protein kinase 0.0092 0.0187 0.0167
Echinococcus granulosus casein kinase I alpha 0.0117 0.0318 0.0285
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0062 0.0033 0.0021
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0088 0.017 0.017
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0576 0.0564
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0608 0.0596
Loa Loa (eye worm) hypothetical protein 0.0109 0.0277 0.0277
Echinococcus granulosus tyrosine protein kinase Fyn 0.0311 0.1309 0.1279
Loa Loa (eye worm) hypothetical protein 0.0088 0.0166 0.0166
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0214 0.0814 0.0796
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0174 0.0608 0.0608
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0093 0.0192 0.0179
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0093 0.0192 0.0179
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0222 0.0853 0.0853
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0088 0.0166 0.0146
Brugia malayi Protein kinase domain containing protein 0.0303 0.1268 0.1268
Plasmodium vivax serine/threonine protein kinase, putative 0.0091 0.0183 0.287
Brugia malayi SRC-1 0.0311 0.1309 0.1309
Schistosoma mansoni protein kinase 0.0082 0.0135 0.0123
Plasmodium falciparum serine/threonine protein kinase, putative 0.0155 0.0513 0.8398
Leishmania major casein kinase, putative 0.0117 0.0318 0.0306
Onchocerca volvulus Tyrosine kinase homolog 0.0562 0.2599 0.2558
Brugia malayi C1-like domain containing protein 0.0222 0.0853 0.0853
Trichomonas vaginalis AGC family protein kinase 0.0196 0.0724 0.0712
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0122 0.0341 0.5522
Brugia malayi SH2 domain containing protein 0.0088 0.017 0.017
Echinococcus multilocularis dual specificity 0.0094 0.0198 0.0179
Trypanosoma cruzi casein kinase, putative 0.0117 0.0318 0.0306
Plasmodium falciparum casein kinase 1 0.0117 0.0318 0.5135
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.114 0.1129
Entamoeba histolytica casein kinase, putative 0.0117 0.0318 0.0306
Giardia lamblia Kinase, CAMK CAMKL 0.0097 0.0217 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0217 0.0204
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0174 0.0608 0.0608
Giardia lamblia Kinase, CMGC SRPK 0.0091 0.0183 0.0171
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0652 0.3059 0.3059
Schistosoma mansoni cell adhesion molecule 0.0117 0.0316 0.0304
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0089 0.0172 0.1315
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0089 0.0175 0.0141
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0092 0.0187 0.1433
Entamoeba histolytica protein kinase, putative 0.0079 0.0124 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0972 0.0961
Loa Loa (eye worm) hypothetical protein 0.011 0.0278 0.0278
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0972 0.0961
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0197 0.0725 0.0707
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0424 0.0412
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0271 0.1104 0.1073
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0168 0.0576 0.0557
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0228 0.0885 0.0867
Schistosoma mansoni tyrosine kinase 0.0084 0.0147 0.0135
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0322
Leishmania major protein kinase A catalytic subunit isoform 1 0.0122 0.0341 0.0329
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0467 0.2113 0.2113
Loa Loa (eye worm) CDC7 protein kinase 0.0098 0.0219 0.0219
Echinococcus multilocularis dual specificity protein kinase clk2 0.0164 0.0556 0.0537
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0109 0.0277 0.2176
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0295 0.1229 0.1229
Giardia lamblia Kinase, CMGC CLK 0.0164 0.0556 0.0544
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0341 0.0329
Loa Loa (eye worm) SRC-1 0.0311 0.1309 0.1309
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0242 0.0956 0.0938
Trichomonas vaginalis CAMK family protein kinase 0.0985 0.4768 0.4761
Giardia lamblia Kinase, NEK 0.0146 0.0463 0.0452
Brugia malayi Protein kinase domain containing protein 0.0088 0.017 0.017
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.006 0.0027 0.0014
Plasmodium falciparum calcium-dependent protein kinase 3 0.0109 0.0277 0.4442
Giardia lamblia Kinase, STE STE20 0.0094 0.0199 0.0187
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0174 0.0611 0.0578
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0464 0.2096 0.2081
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0556 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Plasmodium falciparum serine/threonine protein kinase KIN 0.0097 0.0217 0.3428
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0122 0.0341 0.0329
Brugia malayi hypothetical protein 0.0058 0.0015 0.0015
Onchocerca volvulus 0.0182 0.0652 0.06
Echinococcus multilocularis casein kinase I delta 0.0117 0.0318 0.0299
Echinococcus multilocularis casein kinase I delta 0.0117 0.0318 0.0299
Echinococcus multilocularis 0.0179 0.0634 0.0615
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0122 0.0341 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0219 0.0206
Trypanosoma cruzi casein kinase, putative 0.0117 0.0318 0.0306
Brugia malayi Variant SH3 domain containing protein 0.0086 0.0158 0.0158
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0092 0.0187 0.0175
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0302 0.1265 0.1248
Trichomonas vaginalis CK1 family protein kinase 0.0117 0.0318 0.0306
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0131 0.039 0.039
Schistosoma mansoni growth factor receptor-bound protein 0.0086 0.0158 0.0146
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0097 0.0217 0.0197
Onchocerca volvulus 0.0066 0.0058 0.0003
Schistosoma mansoni tyrosine kinase 0.0457 0.2058 0.2048
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0725 0.0714
Onchocerca volvulus 0.0088 0.017 0.0116
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0155 0.0513 0.8398
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0228 0.0885 0.0853
Entamoeba histolytica cell division protein kinase 2, putative 0.0174 0.0608 0.0596
Leishmania major protein kinase A catalytic subunit isoform 2 0.0122 0.0341 0.0329
Echinococcus multilocularis Glutaredoxin protein 5 0.0127 0.037 0.0351
Entamoeba histolytica serine/threonine protein kinase, putative 0.2006 1 1
Brugia malayi Protein kinase domain containing protein 0.0623 0.2912 0.2912
Echinococcus granulosus c-Jun N-terminal kinases 0.0278 0.114 0.1109
Schistosoma mansoni protein kinase 0.0242 0.0956 0.0945
Schistosoma mansoni hypothetical protein 0.0115 0.0307 0.0295
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0068 0.0067 0.0054
Echinococcus multilocularis mitogen activated protein kinase 11 0.0299 0.1251 0.1234
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0092 0.0187 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0198 0.0186
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0254 0.102 0.0989
Trypanosoma brucei cdc2-related kinase 1 0.0174 0.0608 0.0596
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0149 0.0482 0.047
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0174 0.0608 0.0608
Echinococcus multilocularis myosin iiia 0.0093 0.0192 0.0172
Echinococcus multilocularis protein kinase shaggy 0.0138 0.0424 0.0405
Echinococcus granulosus nervana 2 0.0127 0.037 0.0336
Schistosoma mansoni atypical protein kinase C 0.0294 0.1226 0.1215
Echinococcus granulosus protein kinase c iota type 0.0288 0.1194 0.1163
Entamoeba histolytica protein kinase, putative 0.0168 0.0576 0.0564
Echinococcus multilocularis rho associated protein kinase 0.034 0.1461 0.1444
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0109 0.0277 0.4442
Loa Loa (eye worm) AGC/PKA protein kinase 0.0122 0.0341 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0167 0.0571 0.0539
Echinococcus multilocularis tyrosine kinase 0.0088 0.017 0.0151
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Plasmodium vivax calcium-dependent protein kinase, putative 0.0109 0.0277 0.4442
Echinococcus multilocularis calcium dependent protein kinase 0.007 0.0075 0.0056
Echinococcus granulosus protein tyrosine kinase 0.0564 0.2606 0.258
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0088 0.017 0.0151
Brugia malayi Protein kinase domain containing protein 0.0189 0.0684 0.0684
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0197 0.0725 0.0693
Schistosoma mansoni protein kinase C mu 0.0222 0.0853 0.0842
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Echinococcus granulosus protein kinase C gamma type 0.021 0.0792 0.076
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0085 0.0155 0.0143
Loa Loa (eye worm) TK/FAK protein kinase 0.057 0.2637 0.2637
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0091 0.0183 0.0183
Echinococcus granulosus tyrosine protein kinase HCK 0.0224 0.0868 0.0836
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0164 0.0556 0.0544
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0311 0.1309 0.1292
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus granulosus epidermal growth factor receptor 0.041 0.1818 0.1789
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Echinococcus multilocularis insulin receptor 0.0457 0.2058 0.2043
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0146 0.0463 0.7571
Echinococcus multilocularis N chimaerin 0.0081 0.0134 0.0115
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0183 0.0171
Giardia lamblia Kinase, AGC AKT 0.0126 0.0363 0.0351
Loa Loa (eye worm) hypothetical protein 0.0135 0.0406 0.0406
Loa Loa (eye worm) hypothetical protein 0.0123 0.0347 0.0347
Echinococcus granulosus tyrosine protein kinase Srms 0.0088 0.017 0.0136
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0219 0.0206
Plasmodium falciparum protein kinase, putative 0.0082 0.0135 0.2065
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Onchocerca volvulus 0.0147 0.0471 0.0418
Plasmodium vivax serine/threonine kinase-1, putative 0.0164 0.0556 0.9121
Toxoplasma gondii casein kinase I 0.0117 0.0318 0.2515
Schistosoma mansoni tyrosine kinase 0.0088 0.017 0.0158
Brugia malayi Protein kinase domain containing protein 0.0088 0.017 0.017
Echinococcus multilocularis protein kinase c epsilon type 0.0204 0.0763 0.0745
Giardia lamblia Kinase, NEK 0.0146 0.0463 0.0452
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.006 0.0027 0.0014
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0068 0.0067 0.0054
Brugia malayi cell division control protein 2 homolog 0.0174 0.0608 0.0608
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0311 0.1309 0.1279
Plasmodium falciparum calcium-dependent protein kinase 4 0.0109 0.0277 0.4442
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0299 0.1251 0.124
Echinococcus multilocularis expressed protein 0.0091 0.0183 0.0164
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0122 0.0341 0.0329
Loa Loa (eye worm) hypothetical protein 0.0092 0.0188 0.0188
Echinococcus multilocularis 0.0163 0.0553 0.0535
Entamoeba histolytica protein kinase, putative 0.0078 0.0119 0.0106
Plasmodium vivax protein kinase Crk2 0.0174 0.0608 1
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Schistosoma mansoni protein kinase 0.0094 0.0199 0.0187
Brugia malayi Protein kinase domain 0.0094 0.0199 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0814 0.0803
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.0175 0.0175
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0062 0.0033 0.0033
Schistosoma mansoni tyrosine kinase 0.0246 0.098 0.0969
Loa Loa (eye worm) AGC/PKA protein kinase 0.0122 0.0341 0.0341
Brugia malayi Protein kinase domain containing protein 0.0098 0.0219 0.0219
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0131 0.039 0.0378
Echinococcus multilocularis mitogen activated protein kinase 14 0.0299 0.1251 0.1234
Loa Loa (eye worm) hypothetical protein 0.0239 0.0941 0.0941
Trichomonas vaginalis STE family protein kinase 0.0072 0.0084 0.0072
Brugia malayi serine/threonine protein kinase 6 0.0155 0.0513 0.0513
Entamoeba histolytica protein kinase, putative 0.0091 0.0183 0.0171
Brugia malayi casein kinase 1, delta 0.0117 0.0318 0.0318
Brugia malayi Sex muscle abnormal protein 5 0.0086 0.0158 0.0158
Echinococcus granulosus tyrosine kinase 0.0088 0.017 0.0136
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Schistosoma mansoni tyrosine kinase 0.0457 0.2058 0.2048
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0228 0.0885 0.0867
Brugia malayi Protein kinase domain containing protein 0.0069 0.0071 0.0071
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0164 0.0556 0.0544
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0138 0.0424 0.0412
Entamoeba histolytica protein kinase, putative 0.0094 0.0198 0.0186
Trichomonas vaginalis CK1 family protein kinase 0.0117 0.0318 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0608 0.0596
Loa Loa (eye worm) hypothetical protein 0.0088 0.0167 0.0167
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0272 0.0253
Trypanosoma cruzi cdc2-related kinase 3 0.0174 0.0608 0.0596
Trypanosoma brucei protein kinase, putative 0.0138 0.0424 0.0412
Echinococcus granulosus CDC7 cell division cycle 7 0.0098 0.0219 0.0185
Brugia malayi Protein kinase domain containing protein 0.0623 0.2912 0.2912
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0277 0.0265
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.2006 1 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0154 0.0509 0.0476
Brugia malayi Hr1 repeat family protein 0.0301 0.126 0.126
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0311 0.1309 0.1292
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0456 0.0445
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0134 0.0403 0.0391
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0117 0.0318 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0608 0.0596
Entamoeba histolytica casein kinase 1, putative 0.0117 0.0318 0.0306
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0088 0.0166 0.0153
Schistosoma mansoni serine/threonine kinase 0.0229 0.089 0.0879
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0187 0.0175
Echinococcus multilocularis protein kinase c iota type 0.0288 0.1194 0.1177
Brugia malayi Protein kinase domain containing protein 0.019 0.0692 0.0692
Echinococcus granulosus protein kinase c epsilon type 0.0204 0.0763 0.0731
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0168 0.0576 0.0543
Trichomonas vaginalis CAMK family protein kinase 0.0985 0.4768 0.4761
Loa Loa (eye worm) hypothetical protein 0.0129 0.0379 0.0379
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0222 0.0853 0.0853
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0168 0.0576 0.0543
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0161 0.0541 0.0541
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0094 0.0198 0.0186
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus multilocularis CDC7 cell division cycle 7 0.0098 0.0219 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0608 0.0596
Schistosoma mansoni protein kinase 0.0452 0.2035 0.2025
Echinococcus granulosus Glutaredoxin protein 5 0.0127 0.037 0.0336
Brugia malayi SH2 domain containing protein 0.0088 0.017 0.017
Echinococcus granulosus serine:threonine protein kinase 0.0123 0.0347 0.0314
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Echinococcus multilocularis serine:threonine protein kinase 3 0.027 0.11 0.1083
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.0352 0.034
Echinococcus multilocularis cyclin dependent kinase 1 0.0174 0.0608 0.059
Loa Loa (eye worm) AGC/PKG protein kinase 0.0144 0.0455 0.0455
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0092 0.0187 0.0175
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0144 0.0455 0.0436
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0762 0.0751
Plasmodium vivax tyrosine kinase-like protein, putative 0.0089 0.0172 0.2685
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0066 0.0058 0.0058
Echinococcus granulosus dual specificity 0.0094 0.0198 0.0164
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0198 0.0186
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0246 0.098 0.0963
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0138 0.0424 0.0424
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0128 0.0375 0.0363
Plasmodium falciparum protein kinase 5 0.0174 0.0608 1
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus multilocularis PAK box P21 Rho binding 0.0072 0.0084 0.0065
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0115 0.0307 0.0295
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0062 0.0035 0.0015
Schistosoma mansoni kinase 0.1175 0.5742 0.5736
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0556 0.0544
Echinococcus granulosus mitogen activated protein kinase 0.0092 0.0187 0.0153
Brugia malayi Protein kinase domain containing protein 0.0204 0.0762 0.0762
Leishmania major protein kinase A catalytic subunit 0.0122 0.0341 0.0329
Trichomonas vaginalis STE family protein kinase 0.0094 0.0199 0.0187
Brugia malayi intracellular kinase 0.0138 0.0424 0.0424
Onchocerca volvulus 0.0088 0.017 0.0116
Echinococcus multilocularis dual specificity 0.0131 0.039 0.0371
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0088 0.017 0.0136
Echinococcus multilocularis serine:threonine protein kinase N2 0.0301 0.126 0.1243
Giardia lamblia Kinase, CMGC GSK 0.0138 0.0424 0.0412
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0311 0.1309 0.1292
Schistosoma mansoni serine/threonine-protein kinase 0.0175 0.0611 0.06
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0187 0.0175
Brugia malayi Protein kinase domain containing protein 0.0229 0.089 0.089
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.0204 0.0204
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0086 0.0158 0.0158
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0115 0.0307 0.0288
Brugia malayi protein unc-22 0.0066 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0105 0.0255 0.0243
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1043 0.5062 0.5045
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0244 0.097 0.097
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0138 0.0424 0.0412
Echinococcus granulosus calcium activated potassium channel 0.0144 0.0456 0.0423
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0117 0.0318 0.0318
Giardia lamblia Aurora kinase 0.0155 0.0513 0.0501
Entamoeba histolytica protein kinase, putative 0.0155 0.0513 0.0501
Loa Loa (eye worm) AGC/PKN protein kinase 0.0301 0.126 0.126
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0308
Giardia lamblia Kinase, AGC PKA 0.0122 0.0341 0.0329
Giardia lamblia Kinase, CMGC DYRK 0.0094 0.0198 0.0186
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0131 0.039 0.0378
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0097 0.0217 0.0204
Echinococcus multilocularis activin receptor type 0.0082 0.0135 0.0116
Entamoeba histolytica protein kinase, putative 0.0085 0.0155 0.0143
Brugia malayi MAP kinase sur-1 0.0092 0.0187 0.0187
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0094 0.0199 0.018
Brugia malayi p70 ribosomal S6 kinase beta 0.0295 0.1229 0.1229
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0204 0.0762 0.0762
Trichomonas vaginalis STE family protein kinase 0.0146 0.0463 0.0452
Schistosoma mansoni serine/threonine-protein kinase 0.0175 0.0611 0.06
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0078 0.0117 0.0104
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0424 0.0412
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0115 0.0307 0.0295
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0198 0.0186
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0174 0.0611 0.0611
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0311 0.1309 0.1292
Schistosoma mansoni serine/threonine protein kinase 0.034 0.1461 0.145
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0094 0.0198 0.153
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0945 0.0934
Schistosoma mansoni tyrosine kinase 0.0226 0.0874 0.0863
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0175 0.0163
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0299 0.1251 0.124
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Brugia malayi serine/threonine-protein kinase 6 0.0155 0.0513 0.0513
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0174 0.0611 0.0592
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0117 0.0318 0.0306
Trypanosoma cruzi cdc2-related kinase 1 0.0174 0.0608 0.0596
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0883 0.4242 0.5
Echinococcus granulosus casein kinase I alpha 0.0117 0.0318 0.0285
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0115 0.0307 0.0295
Brugia malayi serine/threonine-protein kinase PAK 7 0.0244 0.097 0.097
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Trypanosoma brucei aurora B kinase 0.0155 0.0513 0.0501
Onchocerca volvulus 0.0081 0.0134 0.0079
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0135 0.0123
Entamoeba histolytica protein kinase, putative 0.0224 0.0868 0.0856
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0198 0.0186
Loa Loa (eye worm) hypothetical protein 0.0147 0.0471 0.0471
Onchocerca volvulus 0.0301 0.1259 0.1211
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0411 0.1826 0.181
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0097 0.0217 0.3428
Brugia malayi Immunoglobulin I-set domain containing protein 0.0266 0.1081 0.1081
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0556 0.0544
Plasmodium falciparum cGMP-dependent protein kinase 0.0144 0.0455 0.7433
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0078 0.0119 0.0084
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0138 0.0424 0.0412
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0266 0.1079 0.1048
Brugia malayi protein-tyrosine kinase 0.0271 0.1104 0.1104
Brugia malayi Variant SH3 domain containing protein 0.0081 0.0134 0.0134
Echinococcus granulosus fibroblast growth factor receptor 4 0.0246 0.098 0.0949
Loa Loa (eye worm) TK/ABL protein kinase 0.0302 0.1265 0.1265
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Brugia malayi Protein kinase c protein 2 0.0117 0.0315 0.0315
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0109 0.0277 0.4442
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0168 0.0576 0.0557
Mycobacterium ulcerans haloalkane dehalogenase 0.0883 0.4242 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0174 0.0611 0.0559
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.0198 0.0186
Brugia malayi RhoGAP domain containing protein 0.0081 0.0134 0.0134
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0186 0.0673 0.0673
Trichomonas vaginalis AGC family protein kinase 0.0189 0.0684 0.0672
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0167 0.0571 0.0553
Loa Loa (eye worm) hypothetical protein 0.0168 0.0576 0.0576
Brugia malayi Protein kinase domain containing protein 0.0383 0.1681 0.1681
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0311 0.1309 0.1292
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0214 0.0814 0.0782
Schistosoma mansoni tyrosine kinase 0.0624 0.2916 0.2908
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1268 0.1258
Loa Loa (eye worm) TK/EGFR protein kinase 0.0624 0.2916 0.2916
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0086 0.0158 0.0158
Loa Loa (eye worm) casein kinase 0.0124 0.0351 0.0351
Brugia malayi Fes/CIP4 homology domain containing protein 0.0114 0.0301 0.0301
Brugia malayi Kinase associated domain 1 family protein 0.0105 0.0255 0.0255
Loa Loa (eye worm) CAMK protein kinase 0.0066 0.0058 0.0058
Plasmodium vivax glycogen synthase kinase 3, putative 0.0138 0.0424 0.6908
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0078 0.0119 0.0084
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0515 0.2354 0.2339
Echinococcus multilocularis rac serine:threonine kinase 0.0175 0.0611 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0094 0.0199 0.018
Toxoplasma gondii aurora kinase 0.0155 0.0513 0.4114
Echinococcus multilocularis death associated protein kinase 1 0.0879 0.4223 0.4212
Brugia malayi Protein kinase domain containing protein 0.0123 0.0347 0.0347
Echinococcus multilocularis casein kinase I gamma 0.0163 0.0553 0.0535
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.2006 1 1
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0115 0.0307 0.0295
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0033 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0318 0.0306
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0127 0.037 0.0336
Entamoeba histolytica protein kinase, putative 0.0131 0.039 0.0378
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0463 0.0452
Echinococcus granulosus defective proboscis extension response 0.0088 0.0166 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0763 0.0752
Trichomonas vaginalis STE family protein kinase 0.0094 0.0199 0.0187
Echinococcus granulosus NDR protein kinase 0.0168 0.0576 0.0543
Echinococcus granulosus tyrosine protein kinase Src42A 0.0311 0.1309 0.1279
Schistosoma mansoni tyrosine kinase 0.0128 0.0375 0.0363
Echinococcus multilocularis neuroglian 0.0107 0.0266 0.0247
Trichomonas vaginalis AGC family protein kinase 0.0155 0.0513 0.0501
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0081 0.0135 0.0135
Echinococcus multilocularis epidermal growth factor receptor 0.0624 0.2916 0.2903
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0164 0.0556 0.0544
Echinococcus multilocularis mitogen activated protein kinase 11 0.0299 0.1251 0.1234
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0204 0.0762 0.0762
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0623 0.2912 0.2912
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0217 0.0204
Plasmodium falciparum glycogen synthase kinase 3 0.0138 0.0424 0.6908
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0424 0.0412
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.027 0.11 0.11
Schistosoma mansoni vav2 0.0089 0.0174 0.0162
Schistosoma mansoni protein kinase 0.0204 0.0762 0.0751
Echinococcus granulosus neuroglian 0.0107 0.0266 0.0233
Brugia malayi Doublecortin family protein 0.0161 0.0541 0.0541
Echinococcus granulosus tyrosine protein kinase Blk 0.0271 0.1104 0.1073
Echinococcus multilocularis roundabout 2 0.0137 0.0417 0.0399
Echinococcus multilocularis hypothetical protein 0.0105 0.0255 0.0236
Loa Loa (eye worm) hypothetical protein 0.0095 0.0204 0.0204
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0109 0.0277 0.0277
Echinococcus multilocularis c src tyrosine kinase 0.0128 0.0375 0.0356
Brugia malayi Variant SH3 domain containing protein 0.0086 0.0158 0.0158
Echinococcus granulosus mitogen activated protein kinase 14 0.0299 0.1251 0.122
Loa Loa (eye worm) TK protein kinase 0.0266 0.1081 0.1081
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0122 0.0341 0.0322
Loa Loa (eye worm) TK/EPH protein kinase 0.0126 0.0364 0.0364
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0082 0.014 0.0105
Entamoeba histolytica protein kinase, putative 0.0155 0.0513 0.0501
Loa Loa (eye worm) TK protein kinase 0.0271 0.1104 0.1104
Echinococcus multilocularis casein kinase I alpha 0.0117 0.0318 0.0299
Entamoeba histolytica protein kinase, putative 0.0078 0.0119 0.0106
Entamoeba histolytica protein kinase, putative 0.0109 0.0277 0.0265
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0092 0.0187 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0219 0.0206
Brugia malayi hypothetical protein 0.0115 0.0307 0.0307
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0254 0.102 0.102
Trypanosoma cruzi casein kinase, putative 0.0117 0.0318 0.0306
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0198 0.0186
Brugia malayi Protein kinase domain containing protein 0.0089 0.0175 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0553 0.0541
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0212 0.0804 0.0772
Echinococcus granulosus growth factor receptor bound protein 2 0.0086 0.0158 0.0124
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0088 0.017 0.0158
Echinococcus multilocularis mitogen activated protein kinase 14 0.0299 0.1251 0.1234
Trichomonas vaginalis AGC family protein kinase 0.006 0.0027 0.0014
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0078 0.0119 0.0099
Schistosoma mansoni serine/threonine kinase 0.0168 0.0576 0.0564
Loa Loa (eye worm) AUR protein kinase 0.0155 0.0513 0.0513
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Toxoplasma gondii AGC kinase 0.0122 0.0341 0.2705
Brugia malayi Protein kinase domain containing protein 0.1003 0.4856 0.4856
Brugia malayi Protein kinase domain containing protein 0.0088 0.017 0.017
Brugia malayi Tyrosine-protein kinase abl-1 0.0132 0.0393 0.0393
Toxoplasma gondii AGC kinase 0.0122 0.0341 0.2705
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0464 0.2096 0.2069
Entamoeba histolytica hypothetical protein 0.0131 0.039 0.0378
Echinococcus multilocularis nervana 2 0.0127 0.037 0.0351
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0138 0.0424 0.0405
Giardia lamblia Kinase, PLK 0.2006 1 1
Echinococcus multilocularis NCK adaptor protein 0.0086 0.0158 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0217 0.0204
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0154 0.0509 0.049
Loa Loa (eye worm) TK/INSR protein kinase 0.0457 0.2058 0.2058
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0131 0.039 0.0378
Brugia malayi serine/threonine kinase 12 0.0155 0.0513 0.0513
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0094 0.0198 0.0186
Brugia malayi Protein kinase domain containing protein 0.0204 0.0762 0.0762
Loa Loa (eye worm) hypothetical protein 0.0097 0.0217 0.0217
Trypanosoma brucei SNF1-related protein kinases, putative 0.0097 0.0217 0.0204
Entamoeba histolytica protein kinase 2, putative 0.0167 0.0571 0.056
Trypanosoma cruzi casein kinase, putative 0.0117 0.0318 0.0306
Echinococcus granulosus NCK adaptor protein 0.0086 0.0158 0.0124
Loa Loa (eye worm) TK/FER protein kinase 0.0088 0.017 0.017
Echinococcus granulosus casein kinase I alpha 0.0117 0.0318 0.0285
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0164 0.0556 0.0544
Loa Loa (eye worm) hypothetical protein 0.0095 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0058 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0475 0.2153 0.2153
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0067 0.0054
Onchocerca volvulus 0.0098 0.0219 0.0165
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0189 0.0684 0.0684
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0166 0.0569 0.0569
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.0352 0.034
Echinococcus multilocularis 0.0124 0.0354 0.0335
Echinococcus granulosus tyrosine kinase 0.0271 0.1104 0.1073

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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