Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0362 | 0.0147 | 0.5 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0203 | 0.0057 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.0057 | 0.003 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.6814 | 0.3803 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0362 | 0.0147 | 0.0387 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.0057 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0029 | 0.0002 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Onchocerca volvulus | 0.0362 | 0.0147 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.0057 | 0.003 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0203 | 0.0057 | 0.5 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0362 | 0.0147 | 0.0387 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0203 | 0.0057 | 0.5 |
Toxoplasma gondii | aminopeptidase N protein | 0.0362 | 0.0147 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0362 | 0.0147 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0362 | 0.0147 | 0.0091 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0362 | 0.0147 | 0.5 |
Brugia malayi | hypothetical protein | 0.0362 | 0.0147 | 0.0091 |
Onchocerca volvulus | 0.0362 | 0.0147 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.0147 | 0.0121 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0362 | 0.0147 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0362 | 0.0147 | 0.0091 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0203 | 0.0057 | 0.015 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0362 | 0.0147 | 0.5 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0362 | 0.0147 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0029 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0362 | 0.0147 | 0.0091 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0362 | 0.0147 | 0.0243 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.6814 | 0.3803 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0362 | 0.0147 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0029 | 0.0002 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0362 | 0.0147 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0362 | 0.0147 | 1 |
Trypanosoma brucei | aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0029 | 0.0002 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0362 | 0.0147 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0041 | 0.0109 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0362 | 0.0147 | 0.0387 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0362 | 0.0147 | 0.0121 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0362 | 0.0147 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0362 | 0.0147 | 0.0243 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0362 | 0.0147 | 1 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 1.7751 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.3133 | 0.1717 | 0.167 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.6814 | 0.3803 | 1 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0362 | 0.0147 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0362 | 0.0147 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0362 | 0.0147 | 0.5 |
Loa Loa (eye worm) | aminopeptidase N | 0.0362 | 0.0147 | 0.0121 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0362 | 0.0147 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0362 | 0.0147 | 0.0091 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0362 | 0.0147 | 0.0387 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0029 | 0.0002 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0362 | 0.0147 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0029 | 0.0002 |
Brugia malayi | TATA binding protein associated factor | 0.0362 | 0.0147 | 0.0091 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.0147 | 0.0121 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0362 | 0.0147 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Echinococcus granulosus | Solute carrier family 22 5 | 0.1011 | 0.0515 | 0.1224 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0362 | 0.0147 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0362 | 0.0147 | 0.5 |
Onchocerca volvulus | 0.0362 | 0.0147 | 0.5 | |
Echinococcus multilocularis | aminopeptidase N | 0.0362 | 0.0147 | 0.0243 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.6814 | 0.3803 | 0.3786 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0362 | 0.0147 | 0.5 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0203 | 0.0057 | 0.0002 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0362 | 0.0147 | 1 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0362 | 0.0147 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.0147 | 0.0121 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0362 | 0.0147 | 0.0243 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.