Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0427 | 0.6229 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0168 | 0.2063 | 0.3313 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0343 | 0.4867 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0641 | 0.9665 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0444 | 0.0912 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0444 | 0.0912 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0168 | 0.2063 | 0.424 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0444 | 0.0459 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0343 | 0.4867 | 0.5036 |
Echinococcus granulosus | carboxylesterase 5A | 0.0067 | 0.0444 | 0.0912 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0444 | 0.0459 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0147 | 0.1728 | 0.3551 |
Loa Loa (eye worm) | carboxylesterase | 0.0067 | 0.0444 | 0.0459 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0343 | 0.4867 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0067 | 0.0444 | 0.0713 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0343 | 0.4867 | 0.5036 |
Loa Loa (eye worm) | hypothetical protein | 0.0623 | 0.9365 | 0.969 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0444 | 0.0459 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0067 | 0.0444 | 0.0459 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0641 | 0.9665 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0067 | 0.0444 | 0.0912 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0444 | 0.0912 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0444 | 0.0459 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0343 | 0.4867 | 0.7814 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0444 | 0.0912 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.