Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | protein kinase C II. | 0.076 | 0.1754 | 0.215 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.1667 | 0.6243 | 0.6226 |
Loa Loa (eye worm) | hypothetical protein | 0.0677 | 0.1347 | 0.1704 |
Loa Loa (eye worm) | hypothetical protein | 0.097 | 0.2794 | 0.3596 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.1667 | 0.6243 | 0.6226 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2427 | 1 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0414 | 0.0044 | 0.5 |
Toxoplasma gondii | AGC kinase | 0.0414 | 0.0044 | 0.5 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.1667 | 0.6243 | 0.6226 |
Entamoeba histolytica | protein kinase, putative | 0.0414 | 0.0044 | 0.5 |
Echinococcus granulosus | protein kinase C gamma type | 0.2134 | 0.8553 | 0.8546 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0706 | 0.1492 | 0.1454 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.2134 | 0.8553 | 0.8546 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.1729 | 0.655 | 0.8508 |
Brugia malayi | Protein kinase c protein 2 | 0.2022 | 0.7997 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.196 | 0.769 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1667 | 0.6243 | 0.8107 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2427 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0414 | 0.0044 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0414 | 0.0044 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0677 | 0.1347 | 0.1704 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1091 | 0.3394 | 0.4381 |
Onchocerca volvulus | 0.0677 | 0.1347 | 0.5 | |
Entamoeba histolytica | protein kinase, putative | 0.0414 | 0.0044 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.076 | 0.1754 | 0.1717 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0706 | 0.1492 | 0.1454 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.076 | 0.1754 | 0.1717 |
Echinococcus granulosus | protein kinase c epsilon type | 0.076 | 0.1754 | 0.1717 |
Loa Loa (eye worm) | hypothetical protein | 0.0677 | 0.1347 | 0.1704 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.076 | 0.1754 | 0.2236 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.2427 | 1 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0706 | 0.1492 | 0.1454 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0414 | 0.0044 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.