Detailed information for compound 840281

Basic information

Technical information
  • TDR Targets ID: 840281
  • Name: 3-(2-fluorophenyl)-N-(2-methylsulfanylphenyl) -4,5-dihydro-1,2-oxazole-5-carboxamide
  • MW: 330.377 | Formula: C17H15FN2O2S
  • H donors: 1 H acceptors: 1 LogP: 3.33 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1ccccc1NC(=O)C1ON=C(C1)c1ccccc1F
  • InChi: 1S/C17H15FN2O2S/c1-23-16-9-5-4-8-13(16)19-17(21)15-10-14(20-22-15)11-6-2-3-7-12(11)18/h2-9,15H,10H2,1H3,(H,19,21)
  • InChiKey: CQBVFOSBWRHLMH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(2-fluorophenyl)-N-(2-methylsulfanylphenyl)-4,5-dihydroisoxazole-5-carboxamide
  • 3-(2-fluorophenyl)-N-[2-(methylthio)phenyl]-4,5-dihydroisoxazole-5-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0054 0.0239 0.2051
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0056 0.0154
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.015 0.0767 0.528
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.015 0.0767 0.4896
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0038 0.0492
Brugia malayi bHLH-PAS transcription factor 0.0043 0.018 0.05
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0027 0.0066
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0031 0.0371
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0113 0.0564 0.1417
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.0239 0.0578
Echinococcus multilocularis neurogenic locus notch protein 0.002 0.0056 0.0056
Mycobacterium ulcerans hypothetical protein 0.0054 0.0238 0.1518
Onchocerca volvulus 0.002 0.0056 0.0367
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0071 0.0608
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.005 0.0216 0.0543
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0027 0.0173
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0046 0.0116
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Echinococcus granulosus tumor protein p63 0.0766 0.4134 1
Brugia malayi TAR-binding protein 0.0076 0.036 0.0996
Schistosoma mansoni pyruvate kinase 0.004 0.0163 0.041
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0096 0.0468 0.1297
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0034 0.0129 0.0129
Schistosoma mansoni lamin 0.0032 0.0121 0.0305
Echinococcus multilocularis Niemann Pick C1 protein 0.0319 0.1689 0.1689
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0002 0.0005
Loa Loa (eye worm) patched family protein 0.0014 0.0018 0.0051
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0034 0.0129 0.0312
Loa Loa (eye worm) glutaminase 0.0297 0.1567 0.434
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0084 0.1014
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0152 0.1043
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Plasmodium falciparum acyl-CoA synthetase 0.004 0.0164 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.015 0.0767 0.528
Schistosoma mansoni neuroligin 3 (S09 family) 0.0113 0.0564 0.1417
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Brugia malayi Matrixin family protein 0.0021 0.0059 0.0162
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0297 0.0824
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0036 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0113 0.0564 0.3877
Loa Loa (eye worm) cytochrome P450 family protein 0.0161 0.0825 0.2285
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0468 0.2989
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0238 0.066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0027 0.0066
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0109 0.0542 0.1503
Echinococcus granulosus lamin dm0 0.0032 0.0121 0.0293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.012 0.0768
Echinococcus multilocularis protein dispatched 1 0.0109 0.0542 0.0542
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0046 0.0127
Mycobacterium tuberculosis Carboxylesterase LipT 0.0113 0.0564 0.3877
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.015 0.0767 0.528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0043 0.0275
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Echinococcus multilocularis GPCR, family 2 0.0019 0.0048 0.0048
Echinococcus granulosus acetylcholinesterase 0.067 0.361 0.8731
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0144 0.0361
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0113 0.0564 0.0564
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0121 0.0335
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Brugia malayi Carboxylesterase family protein 0.067 0.361 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0048 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.015 0.0767 0.528
Schistosoma mansoni hypothetical protein 0.0082 0.039 0.0982
Brugia malayi hypothetical protein 0.0196 0.1015 0.281
Loa Loa (eye worm) acetylcholinesterase 1 0.067 0.361 1
Brugia malayi ecdysteroid receptor 0.0019 0.0046 0.0127
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.0427 0.3663
Mycobacterium ulcerans pyruvate kinase 0.004 0.0163 0.1037
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.015 0.0767 0.4896
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0016 0.0031 0.0192
Onchocerca volvulus 0.0113 0.0564 0.3746
Mycobacterium tuberculosis Conserved protein 0.0043 0.018 0.1238
Echinococcus granulosus neurogenic locus notch protein 4 0.002 0.0056 0.0135
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.015 0.0767 0.528
Onchocerca volvulus 0.0014 0.0018 0.0118
Onchocerca volvulus Matrix metalloproteinase homolog 0.0046 0.0198 0.1313
Echinococcus multilocularis musashi 0.0032 0.0121 0.0121
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.0239 0.273
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.0002 0.0002
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0019 0.0124
Leishmania major acetyl-CoA synthetase, putative 0.0016 0.0031 0.0144
Onchocerca volvulus Matrilysin homolog 0.0021 0.0059 0.0386
Loa Loa (eye worm) carboxylesterase 0.0113 0.0564 0.1561
Onchocerca volvulus 0.0063 0.0289 0.1919
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0227 0.1184 0.2978
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0046 0.0046
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.015 0.0767 0.528
Onchocerca volvulus Chorion peroxidase homolog 0.0063 0.0289 0.1919
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0039 0.2077
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0046 0.0116
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.015 0.0767 0.9303
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.003 0.0082
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0307 0.0773
Echinococcus granulosus GPCR family 2 0.0019 0.0048 0.0115
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Onchocerca volvulus 0.0021 0.0059 0.0386
Mycobacterium leprae putative cytochrome p450 0.015 0.0767 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0238 0.1518
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Brugia malayi hypothetical protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0196 0.125
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.018 0.1238
Loa Loa (eye worm) hypothetical protein 0.0043 0.018 0.05
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Muscle positioning protein 4 0.002 0.0056 0.0154
Brugia malayi hypothetical protein 0.003 0.011 0.0303
Onchocerca volvulus 0.0063 0.0289 0.1919
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.018 0.05
Loa Loa (eye worm) notch protein 0.002 0.0056 0.0154
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0027 0.0329
Onchocerca volvulus 0.0014 0.0018 0.0118
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0018
Echinococcus multilocularis 0.015 0.0767 0.0767
Schistosoma mansoni hypothetical protein 0.0034 0.0129 0.0325
Loa Loa (eye worm) hypothetical protein 0.0015 0.0026 0.0073
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0003 0.0003
Leishmania major DNA polymerase eta, putative 0.0023 0.0071 0.0643
Leishmania major acetyl-CoA synthetase, putative 0.0016 0.0031 0.0144
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0036 0.0087
Brugia malayi Cadherin domain containing protein 0.002 0.0056 0.0154
Schistosoma mansoni hypothetical protein 0.0092 0.0449 0.113
Mycobacterium ulcerans hydrolase 0.0025 0.0084 0.053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.0658
Plasmodium falciparum pyruvate kinase 2 0.0021 0.0057 0.3377
Loa Loa (eye worm) hypothetical protein 0.0041 0.0168 0.0465
Onchocerca volvulus 0.0019 0.0046 0.0302
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.036 0.0996
Loa Loa (eye worm) hypothetical protein 0.006 0.0271 0.0751
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0056 0.0154
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Delta serrate ligand family protein 0.002 0.0056 0.0154
Echinococcus granulosus expressed conserved protein 0.021 0.1091 0.2639
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0238 0.066
Schistosoma mansoni tar DNA-binding protein 0.0076 0.036 0.0904
Onchocerca volvulus 0.0014 0.0018 0.0118
Loa Loa (eye worm) hypothetical protein 0.067 0.361 1
Brugia malayi Protein kinase domain containing protein 0.0034 0.0129 0.0358
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Schistosoma mansoni acetylcholinesterase 0.0113 0.0564 0.1417
Mycobacterium ulcerans putative regulatory protein 0.0043 0.018 0.1148
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0054 0.0238 0.1637
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi jmjC domain containing protein 0.0063 0.0288 0.0798
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0281 0.1479 0.4096
Echinococcus multilocularis netrin receptor unc 5 0.0034 0.0129 0.0129
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0046 0.0127
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0002 0.0006
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0015 0.0026 0.0073
Leishmania major hypothetical protein, conserved 0.0043 0.018 0.2003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0046 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.015 0.0767 0.528
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0031 0.0207
Trypanosoma cruzi FHA domain containing protein, putative 0.0011 0.0002 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0121 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi beta-lactamase 0.0043 0.018 0.05
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.011 0.6035
Onchocerca volvulus 0.0014 0.0018 0.0118
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.015 0.0767 0.528
Onchocerca volvulus 0.0016 0.0031 0.02
Giardia lamblia GTOR 0.0054 0.0239 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0046 0.0127
Echinococcus granulosus tar DNA binding protein 0.0076 0.036 0.087
Schistosoma mansoni DNA polymerase eta 0.0023 0.0071 0.0178
Echinococcus granulosus notch 0.002 0.0056 0.0135
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0036 0.0435
Mycobacterium leprae PROBABLE HYDROLASE 0.0025 0.0084 0.1068
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0027 0.0329
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0036 0.0099
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.004 0.0163 0.1119
Echinococcus multilocularis acetylcholinesterase 0.067 0.361 0.361
Schistosoma mansoni tar DNA-binding protein 0.0076 0.036 0.0904
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0144 0.1873
Trichomonas vaginalis spcc417.12 protein, putative 0.0113 0.0564 0.3598
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0016 0.0031 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0046 0.0127
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.002 0.0056 0.0154
Toxoplasma gondii hypothetical protein 0.0014 0.0018 0.0238
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0046 0.0127
Onchocerca volvulus 0.0112 0.0558 0.3706
Plasmodium vivax pyruvate kinase, putative 0.004 0.0163 0.9028
Brugia malayi Pre-SET motif family protein 0.025 0.1313 0.3637
Echinococcus multilocularis para nitrobenzyl esterase 0.0113 0.0564 0.0564
Loa Loa (eye worm) patched family protein 0.0014 0.0018 0.0051
Echinococcus multilocularis cpg binding protein 0.0032 0.0122 0.0122
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0043 0.0523
Echinococcus granulosus slit 2 protein 0.002 0.0056 0.0135
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0016 0.0031 0.0399
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.015 0.0767 0.4896
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0454
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0289 0.0801
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0043 0.0523
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0036 0.0099
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.002 0.0056 0.014
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Schistosoma mansoni pyruvate kinase 0.004 0.0163 0.041
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0036 0.0468
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.018 0.0436
Loa Loa (eye worm) hypothetical protein 0.0054 0.0238 0.066
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0046 0.0127
Onchocerca volvulus 0.0063 0.0289 0.1919
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0071 0.0859
Echinococcus multilocularis slit 2 protein 0.002 0.0056 0.0056
Onchocerca volvulus Protein patched homolog 0.0014 0.0018 0.0118
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0003 0.0009
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0071 0.0196
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0016 0.0031 0.0192
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0297 0.072
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0031 0.0085
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0059 0.0162
Echinococcus multilocularis tar DNA binding protein 0.0076 0.036 0.036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.015 0.0767 0.4896
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0238 0.2721
Loa Loa (eye worm) pyruvate kinase 0.004 0.0163 0.0452
Brugia malayi cytochrome P450 0.015 0.0767 0.2125
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0046 0.0127
Toxoplasma gondii propionate-CoA ligase 0.0016 0.0031 0.0399
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.0002 0.0006
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0113 0.0564 0.3877
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.011 0.6646
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0239 0.0662
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.015 0.0767 0.528
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0152 0.1043
Onchocerca volvulus 0.0109 0.0542 0.3605
Trichomonas vaginalis antibiotic synthetase, putative 0.0016 0.0031 0.0195
Schistosoma mansoni coup transcription factor 0.0019 0.0046 0.0116
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0048 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0043 0.0275
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Echinococcus granulosus carboxylesterase 5A 0.067 0.361 0.8731
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0071 0.0484
Giardia lamblia Pyruvate kinase 0.004 0.0163 0.6815
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0046 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0076 0.036 0.0904
Schistosoma mansoni notch 0.002 0.0056 0.014
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0238 0.2721
Loa Loa (eye worm) hypothetical protein 0.0088 0.0427 0.1182
Echinococcus granulosus neurogenic locus notch protein 0.002 0.0056 0.0135
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0054 0.0238 0.3089
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0011 0.0006 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0179 0.114
Onchocerca volvulus 0.002 0.0056 0.0367
Brugia malayi protein C24B5.3 0.0014 0.0018 0.0051
Schistosoma mansoni hypothetical protein 0.003 0.0106 0.0267
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0071 0.0859
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.012
Loa Loa (eye worm) hypothetical protein 0.0054 0.0238 0.066
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0002 0.0015
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0289 0.0801
Plasmodium vivax acyl-CoA synthetase, putative 0.004 0.0164 0.908
Brugia malayi RNA binding protein 0.0076 0.036 0.0996
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0045 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.015 0.0767 0.528
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.066
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Entamoeba histolytica acyl-coA synthetase, putative 0.0054 0.0238 0.2045
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.0163 0.1041
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.015 0.0767 0.528
Onchocerca volvulus 0.0015 0.0027 0.0177
Loa Loa (eye worm) hypothetical protein 0.004 0.0163 0.0452
Onchocerca volvulus Slit protein homolog 0.002 0.0056 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.0658
Brugia malayi Matrixin family protein 0.0021 0.0059 0.0162
Echinococcus multilocularis tumor protein p63 0.0766 0.4134 0.4134
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0071 0.0178
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0043 0.0119
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0002 0.0026
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.015 0.0767 0.9303
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0027 0.0101
Loa Loa (eye worm) hypothetical protein 0.0043 0.018 0.05
Leishmania major pyruvate kinase 0.004 0.0163 0.1787
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0019 0.0231
Echinococcus granulosus protein jagged 2 0.002 0.0056 0.0135
Echinococcus granulosus survival motor neuron protein 1 0.0536 0.2877 0.6958
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0048 0.0132
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.0002 0.0005
Echinococcus multilocularis notch 0.002 0.0056 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Brugia malayi hypothetical protein 0.0113 0.0564 0.1561
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0238 0.2721
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Echinococcus granulosus lamin 0.0032 0.0121 0.0293
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0036 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0142 0.0906
Brugia malayi hypothetical protein 0.0536 0.2877 0.7969
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0144 0.0144
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0238 0.1518
Echinococcus multilocularis pyruvate kinase 0.0032 0.0117 0.0117
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0027 0.0329
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi Hemopexin family protein 0.003 0.0106 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0239 0.1525
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0046 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0043 0.0275
Brugia malayi Pre-SET motif family protein 0.0036 0.0144 0.0398
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0161 0.0825 0.5263
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0036 0.0099
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0238 0.1637
Loa Loa (eye worm) hypothetical protein 0.0117 0.0586 0.1624
Loa Loa (eye worm) glutaminase 2 0.0297 0.1567 0.434
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.015 0.0767 0.4896
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0289 0.0801
Brugia malayi hypothetical protein 0.0014 0.0018 0.0051
Mycobacterium leprae conserved hypothetical protein 0.0043 0.018 0.2333
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.012
Loa Loa (eye worm) STAT protein 0.0309 0.1635 0.4529
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Brugia malayi Carboxylesterase family protein 0.0113 0.0564 0.1561
Echinococcus granulosus dna polymerase kappa 0.0023 0.0071 0.0171
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.0239 0.2898
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0031 0.0085
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.015 0.0767 0.528
Echinococcus granulosus sterol regulatory element binding protein 0.0096 0.0468 0.1132
Loa Loa (eye worm) hypothetical protein 0.0043 0.018 0.05
Brugia malayi Carboxylesterase family protein 0.0113 0.0564 0.1561
Onchocerca volvulus 0.0036 0.0144 0.0952
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0152 0.1043
Entamoeba histolytica hypothetical protein 0.0082 0.039 0.3351
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0067 0.4034
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0031 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0289 0.0801
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0046 0.0111
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0454
Onchocerca volvulus Putative cubilin 0.002 0.0056 0.0367
Brugia malayi Pyruvate kinase, muscle isozyme 0.004 0.0163 0.0452
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0002 0.0011
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0289 0.0801
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.012
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0027 0.0173
Brugia malayi hypothetical protein 0.0011 0.0002 0.0005
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.0239 0.0239
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Leishmania major pyruvate kinase 0.004 0.0163 0.1787
Giardia lamblia Pyruvate kinase 0.0021 0.0057 0.2349
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0016 0.0031 0.0031
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Echinococcus multilocularis pyruvate kinase 0.004 0.0163 0.0163
Onchocerca volvulus Peroxidasin homolog 0.0063 0.0289 0.1919
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0016 0.0031 0.0399
Schistosoma mansoni notch 0.002 0.0056 0.014
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0046 0.0127
Echinococcus granulosus death domain containing protein 0.0034 0.0129 0.0312
Onchocerca volvulus 0.002 0.0056 0.0367
Schistosoma mansoni survival motor neuron protein 0.0109 0.0542 0.1364
Loa Loa (eye worm) hypothetical protein 0.0034 0.0129 0.0358
Onchocerca volvulus 0.0113 0.0564 0.3746
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0043 0.0043
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0288 0.0288
Mycobacterium ulcerans glutaminase 0.0297 0.1567 1
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.018 0.1148
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0046 0.0116
Schistosoma mansoni cpg binding protein 0.0032 0.0122 0.0306
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.018 0.2187
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.015 0.0767 0.4896
Onchocerca volvulus 0.0031 0.0112 0.0742
Brugia malayi Matrixin family protein 0.0021 0.0059 0.0162
Echinococcus multilocularis pyruvate kinase 0.0021 0.0057 0.0057
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.0239 0.2898
Onchocerca volvulus Neurogenic locus notch protein homolog 0.002 0.0056 0.0367
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0129 0.0358
Onchocerca volvulus 0.0016 0.0031 0.02
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Plasmodium falciparum pyruvate kinase 0.004 0.0163 0.9943
Brugia malayi glutaminase DH11.1 0.0297 0.1567 0.434
Loa Loa (eye worm) patched family protein 0.0014 0.0018 0.0051
Brugia malayi notch-like transmembrane receptor 0.002 0.0056 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0179 0.114
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Onchocerca volvulus 0.003 0.0106 0.0704
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0071 0.0452
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0031 0.0371
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0016 0.0031 0.1776
Echinococcus multilocularis neurogenic locus protein delta 0.002 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0196 0.1015 0.281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0179 0.114
Brugia malayi nuclear hormone receptor 0.0019 0.0046 0.0127
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0002 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0048 0.0132
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0289 0.0801
Schistosoma mansoni topbp1 0.0011 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Echinococcus granulosus acetylcholinesterase 0.067 0.361 0.8731
Brugia malayi Cytochrome P450 family protein 0.0161 0.0825 0.2285
Giardia lamblia Replication factor C, subunit 1 0.0011 0.0002 0.0052
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.0163 0.1041
Loa Loa (eye worm) hypothetical protein 0.0536 0.2877 0.7969
Schistosoma mansoni intermediate filament proteins 0.0032 0.0121 0.0305
Schistosoma mansoni hypothetical protein 0.0041 0.0168 0.0422
Brugia malayi Bloom's syndrome protein homolog 0.0026 0.0084 0.0233
Echinococcus granulosus cpg binding protein 0.0032 0.0122 0.0294
Loa Loa (eye worm) hypothetical protein 0.0034 0.0131 0.0364
Toxoplasma gondii patched family protein 0.0014 0.0018 0.0238
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.0179 0.1985
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Echinococcus multilocularis pyruvate kinase 0.0021 0.0057 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0031 0.0207
Loa Loa (eye worm) carboxylesterase 0.0113 0.0564 0.1561
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.011 0.1328
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0071 0.0178
Schistosoma mansoni cellular tumor antigen P53 0.0112 0.0558 0.1402
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0071 0.0859
Trypanosoma brucei unspecified product 0.0023 0.0071 0.0859
Loa Loa (eye worm) matrixin family protein 0.0051 0.0221 0.0611
Schistosoma mansoni notch 0.0021 0.0058 0.0146
Echinococcus multilocularis BC026374 protein (S09 family) 0.0113 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Echinococcus multilocularis neurogenic locus notch protein 4 0.002 0.0056 0.0056
Echinococcus multilocularis protein jagged 2 0.002 0.0056 0.0056
Echinococcus multilocularis bloom syndrome protein 0.0026 0.0084 0.0084
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0036 0.0435
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.015 0.0767 0.4896
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0032 0.0382
Echinococcus multilocularis Niemann Pick C1 protein 0.0223 0.1165 0.1165
Brugia malayi jmjC domain containing protein 0.0017 0.0036 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.015 0.0767 0.528
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0046 0.0302
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.015 0.0767 0.4896
Echinococcus multilocularis neurogenic locus notch protein 0.002 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0238 0.1518
Brugia malayi hypothetical protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0017 0.0036 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.018 0.2187
Schistosoma mansoni notch 0.002 0.0056 0.014
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0016 0.0031 0.0207
Brugia malayi Matrixin family protein 0.0051 0.0221 0.0611
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.018 0.1151
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0288 0.0696
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.018 0.1238
Schistosoma mansoni BC026374 protein (S09 family) 0.0113 0.0564 0.1417
Loa Loa (eye worm) hypothetical protein 0.0021 0.0059 0.0162
Echinococcus multilocularis neuroligin 0.0113 0.0564 0.0564
Entamoeba histolytica hypothetical protein 0.0082 0.039 0.3351
Schistosoma mansoni cpg binding protein 0.0031 0.0112 0.0282
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0011 0.0002 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0031 0.0085
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0002 0.0005
Brugia malayi Carboxylesterase family protein 0.0113 0.0564 0.1561
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0027 0.0027
Brugia malayi Cytochrome P450 family protein 0.0161 0.0825 0.2285
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0016 0.0031 0.0371
Giardia lamblia DINP protein human, muc B family 0.0023 0.0071 0.2947
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.0239 0.273
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0054 0.0239 0.2051
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Onchocerca volvulus 0.002 0.0056 0.0367
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.015 0.0767 0.4896
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0018 0.0045
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0003 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.018 0.1151
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Loa Loa (eye worm) hypoxia-induced factor 1 0.0181 0.0932 0.2581
Treponema pallidum DNA ligase (lig) 0.0011 0.0002 0.5
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0034 0.0131 0.033
Loa Loa (eye worm) hypothetical protein 0.0112 0.0558 0.1545
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0271 0.0751
Schistosoma mansoni pyruvate kinase 0.0021 0.0057 0.0142
Leishmania major hypothetical protein, conserved 0.0017 0.0036 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0011
Trichomonas vaginalis glutaminase, putative 0.0297 0.1567 1
Schistosoma mansoni transcription factor LCR-F1 0.0082 0.039 0.0982
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0056 0.0154
Brugia malayi hypothetical protein 0.0082 0.039 0.1082
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Brugia malayi Cadherin domain containing protein 0.002 0.0056 0.0154
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0046 0.0046
Onchocerca volvulus Matrilysin homolog 0.0046 0.0198 0.1313
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0046 0.0127
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.018 0.1238
Brugia malayi Matrixin family protein 0.0021 0.0059 0.0162
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.018 0.1151
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Loa Loa (eye worm) hypothetical protein 0.0016 0.0031 0.0085
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0016 0.0031 0.0207
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Loa Loa (eye worm) pyruvate kinase 0.004 0.0163 0.0452
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0075
Trypanosoma cruzi cytochrome P450, putative 0.0161 0.0825 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0454
Loa Loa (eye worm) pyruvate kinase-PB 0.0028 0.0097 0.0268
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0046 0.0302
Echinococcus multilocularis Ankyrin 0.0034 0.0131 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Brugia malayi Peroxidasin 0.0063 0.0289 0.0801
Onchocerca volvulus 0.0014 0.0018 0.0118
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.015 0.0767 0.4896
Brugia malayi hypothetical protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) beta-lactamase 0.0043 0.018 0.05
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0027 0.0329
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0271 0.0751
Brugia malayi topoisomerase 0.0011 0.0002 0.0005
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.011 0.1328
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Schistosoma mansoni cytochrome P450 0.015 0.0767 0.1929
Toxoplasma gondii ABC1 family protein 0.0043 0.018 0.2351
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Mycobacterium tuberculosis Conserved protein 0.0043 0.018 0.1238
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Echinococcus granulosus para nitrobenzyl esterase 0.0113 0.0564 0.1363
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0046 0.0116
Echinococcus granulosus nuclear factor of activated T cells 5 0.033 0.1751 0.4236
Loa Loa (eye worm) hypothetical protein 0.0032 0.0121 0.0335
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.018 0.1238
Loa Loa (eye worm) RNA binding protein 0.0076 0.036 0.0996
Echinococcus multilocularis peroxidasin 0.0063 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Brugia malayi PAS domain containing protein 0.0058 0.0263 0.0729
Loa Loa (eye worm) carboxylesterase 0.067 0.361 1
Echinococcus granulosus protein jagged 1 0.002 0.0056 0.0135
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0011 0.0002 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0144 0.0361
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.0239 0.0601
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0036 0.0036
Brugia malayi follicle stimulating hormone receptor 0.0281 0.1479 0.4096
Giardia lamblia Sgs1 DNA helicase, putative 0.0011 0.0002 0.0062
Echinococcus granulosus neurogenic locus notch protein 0.002 0.0056 0.0135
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.018 0.1238
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Patched related family protein 10 0.0014 0.0018 0.0051
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Echinococcus granulosus BC026374 protein S09 family 0.0113 0.0564 0.1363
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0046 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0046 0.0111
Schistosoma mansoni glutaminase 0.0297 0.1567 0.394
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0129 0.0358
Mycobacterium leprae Probable pyruvate kinase PykA 0.004 0.0163 0.2106
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0046 0.0046
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0046 0.0046
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Loa Loa (eye worm) animal heme peroxidase 0.0063 0.0289 0.0801
Schistosoma mansoni hypothetical protein 0.0092 0.0449 0.113
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0046 0.0116
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0238 0.066
Mycobacterium tuberculosis Conserved protein 0.0043 0.018 0.1238
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.015 0.0767 0.4896
Onchocerca volvulus Dual oxidase homolog 0.0063 0.0289 0.1919
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0168 0.0465
Brugia malayi Blistered cuticle protein 3 0.0063 0.0289 0.0801
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.003 0.0072
Onchocerca volvulus Peroxidasin homolog 0.0063 0.0289 0.1919
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.001 0.0001 0.0003
Brugia malayi CHE-14 protein 0.0096 0.0468 0.1297
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.015 0.0767 0.4896
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0046 0.0127
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.015 0.0767 0.4896
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0071 0.0449
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.018 0.05
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0016 0.0031 0.0207
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0043 0.0275
Onchocerca volvulus 0.0016 0.0031 0.02
Echinococcus granulosus phd:f box containing protein 0.0017 0.0036 0.0087
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0269 0.3511
Leishmania major lanosterol 14-alpha-demethylase, putative 0.015 0.0767 0.9287
Leishmania major cytochrome p450-like protein 0.015 0.0767 0.9287
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.0658
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.0163 0.1977
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0046 0.0111
Schistosoma mansoni lamin 0.0032 0.0121 0.0305
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0027 0.0173
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.018 0.1238
Schistosoma mansoni microtubule-associated protein tau 0.0737 0.3976 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0059 0.0162
Toxoplasma gondii pyruvate kinase PyK1 0.004 0.0163 0.2125
Echinococcus granulosus cytochrome P450 2K1 0.015 0.0767 0.1856
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0119 0.0757
Loa Loa (eye worm) hypothetical protein 0.038 0.2025 0.5609
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0046 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Echinococcus multilocularis fat cadherin tumor suppressor 0.002 0.0056 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0046 0.0111
Brugia malayi EGF-like domain containing protein 0.002 0.0056 0.0154
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0045 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0144 0.0361
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0055 0.0138
Loa Loa (eye worm) hypothetical protein 0.0025 0.0084 0.0231
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0031 0.0085
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0002 0.0026
Loa Loa (eye worm) CYP4Cod1 0.0161 0.0825 0.2285
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0031 0.0085
Onchocerca volvulus 0.0014 0.0018 0.0118
Leishmania major protein kinase, putative 0.0015 0.0027 0.0101
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0238 0.2045
Loa Loa (eye worm) cytochrome P450 0.015 0.0767 0.2125
Loa Loa (eye worm) hypothetical protein 0.0032 0.0118 0.0327
Onchocerca volvulus 0.0032 0.0121 0.0802
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0289 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0082 0.039 0.039
Trypanosoma cruzi cytochrome p450-like protein, putative 0.015 0.0767 0.9303
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0016 0.0031 0.0207
Loa Loa (eye worm) cytochrome P450 family protein 0.015 0.0767 0.2125
Mycobacterium ulcerans beta-lactamase 0.0043 0.018 0.1148
Brugia malayi Sulfatase family protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0006 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Chlamydia trachomatis pyruvate kinase 0.004 0.0163 0.9943
Trypanosoma brucei pyruvate kinase 1 0.004 0.0163 0.1977
Echinococcus granulosus pyruvate kinase 0.0021 0.0057 0.0137
Brugia malayi hypothetical protein 0.0146 0.0742 0.2057
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0046 0.0046
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0163 0.1081
Schistosoma mansoni topbp1 0.0011 0.0002 0.0004
Echinococcus granulosus Niemann Pick C1 protein 0.0319 0.1689 0.4085
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0046 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0002 0.0022
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0016 0.0031 0.0262
Echinococcus granulosus protein jagged 2 0.002 0.0056 0.0135
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0027 0.0173
Onchocerca volvulus Peroxidase homolog 0.0063 0.0289 0.1919
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0223 0.1165 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0132
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0076 0.036 0.0871
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0297 0.0748
Echinococcus granulosus dna polymerase eta 0.0023 0.0071 0.0171
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0016 0.0031 0.0192
Plasmodium falciparum lipid/sterol:H+ symporter 0.0014 0.0018 0.1018
Mycobacterium ulcerans carboxylesterase, LipT 0.0113 0.0564 0.3596
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.015 0.0767 0.9303
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.018 0.2187
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.015 0.0767 0.528
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi Carboxylesterase family protein 0.067 0.361 1
Echinococcus multilocularis pyruvate kinase 0.004 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Onchocerca volvulus 0.0113 0.0564 0.3746
Schistosoma mansoni septate junction protein 0.002 0.0056 0.014
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.015 0.0767 0.4896
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Schistosoma mansoni cpg binding protein 0.0032 0.0122 0.0306
Toxoplasma gondii cytochrome p450 superfamily protein 0.015 0.0767 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0152 0.1043
Brugia malayi jmjC domain containing protein 0.0017 0.0036 0.0099
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0027 0.0075
Loa Loa (eye worm) TAR-binding protein 0.0076 0.036 0.0996
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0016 0.0031 0.0376
Loa Loa (eye worm) hypothetical protein 0.0023 0.0071 0.0196
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0016 0.0031 0.0371
Loa Loa (eye worm) hypothetical protein 0.0096 0.0468 0.1297
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0121 0.0335
Loa Loa (eye worm) hypothetical protein 0.0021 0.0059 0.0162
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0046 0.0127
Entamoeba histolytica hypothetical protein 0.0011 0.0002 0.0015
Onchocerca volvulus 0.0054 0.0238 0.1582
Onchocerca volvulus 0.0043 0.018 0.1196
Echinococcus multilocularis neural cadherin 0.002 0.0056 0.0056
Trichomonas vaginalis esterase, putative 0.0043 0.018 0.1151
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.018 0.0454
Onchocerca volvulus 0.0285 0.1504 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0054 0.0238 0.1518
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0112 0.031
Brugia malayi Cytochrome P450 family protein 0.015 0.0767 0.2125
Loa Loa (eye worm) patched family protein 0.0014 0.0018 0.0051
Brugia malayi protein C24B5.3 0.0014 0.0018 0.0051
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.018 0.1151
Schistosoma mansoni ankyrin 23/unc44 0.0034 0.0129 0.0325
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Entamoeba histolytica hypothetical protein 0.0082 0.039 0.3351
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0006
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.015 0.0767 0.4896
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.011 0.1328
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0032 0.0382
Loa Loa (eye worm) cytochrome P450 family protein 0.0161 0.0825 0.2285
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0048 0.0115
Brugia malayi Death domain containing protein 0.0034 0.0129 0.0358
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.018 0.0454
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0025 0.0084 0.0571
Loa Loa (eye worm) hypothetical protein 0.067 0.361 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0019 0.0231
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Leishmania major protein kinase, putative 0.0015 0.0027 0.0101
Echinococcus multilocularis acetylcholinesterase 0.067 0.361 0.361
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0032 0.0382
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0071 0.0196
Echinococcus multilocularis pyruvate kinase 0.0021 0.0057 0.0057
Loa Loa (eye worm) oxidoreductase 0.0016 0.0031 0.0085
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0016 0.0031 0.0192
Loa Loa (eye worm) blistered cuticle protein 3 0.0063 0.0289 0.0801
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.015 0.0767 0.528
Toxoplasma gondii patched family protein 0.0014 0.0018 0.0238
Toxoplasma gondii pyruvate kinase PyKII 0.0021 0.0057 0.0737
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.018 0.1238
Giardia lamblia High cysteine protein 0.002 0.0056 0.2311
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Cytochrome P450 family protein 0.015 0.0767 0.2125
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0046 0.0127
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0016 0.0031 0.0192
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0288 0.0288
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0071 0.0859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0179 0.114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.066
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.015 0.0767 0.528
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.015 0.0767 0.4896
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0046 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0173
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.011 0.1428
Schistosoma mansoni cell polarity protein 0.002 0.0056 0.014
Brugia malayi hypoxia-induced factor 1 0.0181 0.0932 0.2581
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) patched family protein 0.0014 0.0018 0.0051
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0012 0.001 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Onchocerca volvulus 0.0043 0.018 0.1196
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0015 0.0027 0.1565
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.015 0.0767 0.528
Loa Loa (eye worm) hypothetical protein 0.0043 0.018 0.05
Brugia malayi Myosin head containing protein 0.0014 0.0018 0.0051
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0002 0.0023
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0144 0.0348
Plasmodium vivax JmjC domain containing protein 0.0017 0.0036 0.191
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0046 0.0127
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.0002 0.0002
Onchocerca volvulus 0.002 0.0053 0.035
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0163 0.1081
Trypanosoma brucei unspecified product 0.0016 0.0032 0.0382
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0036 0.009
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.0163 0.1977
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0046 0.0127
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0036 0.0036
Leishmania major DNA polymerase kappa, putative 0.0023 0.0071 0.0643
Echinococcus multilocularis dna polymerase eta 0.0023 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0043 0.0275
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Echinococcus granulosus pyruvate kinase 0.004 0.0163 0.0394
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0048 0.0048
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0046 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.066
Echinococcus multilocularis protein jagged 1 0.002 0.0056 0.0056
Echinococcus granulosus neural cadherin 0.002 0.0056 0.0135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Echinococcus multilocularis survival motor neuron protein 1 0.0536 0.2877 0.2877
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0002 0.0011
Schistosoma mansoni DNA helicase recq5 0.0011 0.0002 0.0005
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0454
Loa Loa (eye worm) hypothetical protein 0.0043 0.018 0.05
Onchocerca volvulus 0.0011 0.0002 0.0008
Brugia malayi Uncoordinated protein 44 0.0034 0.0129 0.0358
Brugia malayi Pyruvate kinase, M2 isozyme 0.004 0.0163 0.0452
Entamoeba histolytica pyruvate kinase, putative 0.0028 0.0097 0.0831
Schistosoma mansoni tar DNA-binding protein 0.0076 0.036 0.0904
Mycobacterium leprae Conserved hypothetical protein 0.015 0.0767 1
Brugia malayi intermediate filament protein 0.0032 0.0121 0.0335
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Schistosoma mansoni slit 0.002 0.0056 0.014
Loa Loa (eye worm) hypothetical protein 0.0223 0.1165 0.3228
Mycobacterium ulcerans hypothetical protein 0.0043 0.018 0.1148
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.015 0.0767 0.528
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0043 0.0104
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.001 0.0001 0.0003
Schistosoma mansoni notch 0.002 0.0056 0.014
Echinococcus granulosus single minded 2 0.0043 0.018 0.0436
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0036 0.0435
Echinococcus multilocularis carboxylesterase 5A 0.067 0.361 0.361
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0144 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Schistosoma mansoni DNA ligase IV 0.0011 0.0002 0.0004
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0067 0.0808
Echinococcus granulosus Ankyrin 0.0034 0.0131 0.0318
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0082 0.039 0.0944
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0025 0.0084 0.0231
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0119 0.0757
Onchocerca volvulus Protein patched homolog 0.0014 0.0018 0.0118
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0031 0.0144
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0076 0.036 0.036
Brugia malayi nuclear receptor NHR-88 0.0019 0.0046 0.0127
Brugia malayi jmjC domain containing protein 0.0017 0.0036 0.0099
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.015 0.0767 0.4896
Brugia malayi Carboxylesterase family protein 0.0113 0.0564 0.1561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0136 0.0865
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Brugia malayi GCC2 and GCC3 family protein 0.002 0.0056 0.0154
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0046 0.0111
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0071 0.0643
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Mycobacterium ulcerans lipase LipD 0.0043 0.018 0.1148
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0019 0.0163
Schistosoma mansoni hypothetical protein 0.0092 0.0449 0.113
Toxoplasma gondii patched family protein 0.0014 0.0018 0.0238
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0046 0.0116
Plasmodium vivax SET domain protein, putative 0.0036 0.0144 0.7946
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Schistosoma mansoni hypothetical protein 0.0109 0.0542 0.1364
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0027 0.0027
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0238 0.2045
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0046 0.0116
Brugia malayi Patched protein homolog 1 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Onchocerca volvulus 0.0032 0.0121 0.0802
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0268
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.0179 0.2169
Leishmania major cytochrome p450-like protein 0.015 0.0767 0.9287
Plasmodium vivax hypothetical protein, conserved 0.0043 0.018 1
Trichomonas vaginalis set domain proteins, putative 0.0285 0.1501 0.9583
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0239 0.1525
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.015 0.0767 0.528
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Onchocerca volvulus 0.0113 0.0564 0.3746
Echinococcus granulosus Protein patched homolog 1 0.0096 0.0468 0.1132
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.0427 0.3663
Onchocerca volvulus 0.002 0.0056 0.0367
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0011 0.0002 0.5
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0173
Brugia malayi STAT protein, DNA binding domain containing protein 0.0309 0.1635 0.4529
Onchocerca volvulus Neurogenic locus notch homolog 0.0021 0.0058 0.0382
Echinococcus granulosus nibrin 0.0011 0.0002 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0043 0.0119
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0113 0.0564 0.1363
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.036 0.0996
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0031 0.0207
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0238 0.1518
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Brugia malayi hypothetical protein 0.0011 0.0002 0.0005
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.0239 0.2898
Schistosoma mansoni hypothetical protein 0.015 0.0767 0.1929
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.015 0.0767 0.4896
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0046 0.0116
Loa Loa (eye worm) matrixin family protein 0.0046 0.0198 0.0548
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0046 0.0127
Trichomonas vaginalis antibiotic synthetase, putative 0.0016 0.0031 0.0195
Plasmodium vivax acetyl-CoA synthetase, putative 0.0016 0.0031 0.1612
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0113 0.0564 0.3598
Echinococcus multilocularis lamin dm0 0.0032 0.0121 0.0121
Schistosoma mansoni patched 1 0.0096 0.0468 0.1177
Loa Loa (eye worm) hypothetical protein 0.0036 0.0144 0.0398
Echinococcus granulosus fibropellin Ia 0.002 0.0056 0.0135
Onchocerca volvulus 0.0043 0.018 0.1196
Echinococcus granulosus delta-like protein 1 0.002 0.0056 0.0135
Echinococcus granulosus neuroligin 0.0113 0.0564 0.1363
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0276 0.1453 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Loa Loa (eye worm) pyruvate kinase 0.004 0.0163 0.0452
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0036 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Echinococcus multilocularis nibrin 0.0011 0.0002 0.0002
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0016 0.0031 0.0192
Schistosoma mansoni fkbp-rapamycin associated protein 0.001 0.000000018915 0.000000047568
Echinococcus multilocularis lamin 0.0032 0.0121 0.0121
Echinococcus granulosus neurogenic locus protein delta 0.002 0.0056 0.0135
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Echinococcus granulosus microtubule associated protein 2 0.0737 0.3976 0.9618
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0103 0.066
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.018 0.018
Echinococcus multilocularis fibropellin Ia 0.002 0.0056 0.0056
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0002 0.0011
Echinococcus multilocularis expressed conserved protein 0.021 0.1091 0.1091
Brugia malayi steroid hormone receptor 0.0019 0.0046 0.0127
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0016 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.003 0.011 0.0303
Echinococcus granulosus protein jagged 1 0.002 0.0056 0.0135
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Schistosoma mansoni single-minded 0.0058 0.0263 0.0662
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0027 0.0173
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.011 0.6646
Onchocerca volvulus 0.0113 0.0564 0.3746
Mycobacterium leprae Probable lipase LipE 0.0043 0.018 0.2333
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0071 0.0484
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.0163 0.213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.012 0.0768
Echinococcus multilocularis protein jagged 1 0.002 0.0056 0.0056
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0031 0.0085
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0036 0.0036
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0027 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Trypanosoma brucei cytochrome P450, putative 0.0161 0.0825 1
Brugia malayi CXXC zinc finger family protein 0.0031 0.0112 0.031
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0016 0.0031 0.0192
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0046 0.0116
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.0059 0.0147
Echinococcus multilocularis sterol regulatory element binding protein 0.0096 0.0468 0.0468
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0016 0.0031 0.0376
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.018 0.1148
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0043 0.0523
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0084 0.0537
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0002 0.0002
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0016 0.0031 0.0207
Trypanosoma brucei unspecified product 0.0016 0.0032 0.0382
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.004 0.0164 0.1125
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0271 0.0751
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0163 0.1043
Schistosoma mansoni peroxidasin 0.0063 0.0289 0.0727
Plasmodium vivax pyruvate kinase 2, putative 0.0021 0.0057 0.3066
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0288 0.0724
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0048 0.0115
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0046 0.0111
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0039 0.0108
Echinococcus granulosus peroxidasin 0.0063 0.0289 0.0699
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0054 0.0238 0.3089
Toxoplasma gondii EGF family domain-containing protein 0.002 0.0056 0.0725
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0031 0.0207
Brugia malayi Patched family protein 0.0014 0.0018 0.0051
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0036 0.0468
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.0002 0.0005
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0071 0.0452
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Mycobacterium ulcerans acetyl-CoA synthetase 0.0016 0.0031 0.0192
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0019 0.0121
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0163 0.1081
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0113 0.0564 0.1417
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0239 0.0662
Onchocerca volvulus 0.0014 0.0018 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0036 0.009
Onchocerca volvulus 0.0043 0.018 0.1196
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0297 0.0748
Echinococcus multilocularis microtubule associated protein 2 0.0737 0.3976 0.3976
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.025 0.1313 0.3637
Brugia malayi hypothetical protein 0.002 0.0051 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.012 0.0768
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0071 0.0071
Schistosoma mansoni DNA helicase recq1 0.0011 0.0002 0.0005
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0046 0.0046
Onchocerca volvulus Peroxidase homolog 0.0063 0.0289 0.1919
Echinococcus multilocularis neurogenic locus protein delta 0.002 0.0056 0.0056
Trichomonas vaginalis DNA helicase recq1, putative 0.0026 0.0084 0.0537
Echinococcus granulosus pyruvate kinase 0.0021 0.0057 0.0137
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.0239 0.2898
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0071 0.0196
Loa Loa (eye worm) Notch2 0.002 0.0056 0.0154
Schistosoma mansoni notch 0.002 0.0056 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0179 0.114
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0005
Leishmania major cytochrome p450-like protein 0.0161 0.0825 1
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.018 0.1151
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0071 0.0859
Loa Loa (eye worm) hypothetical protein 0.0017 0.0036 0.0099
Entamoeba histolytica hypothetical protein 0.0082 0.039 0.3351
Echinococcus multilocularis nuclear factor of activated T cells 5 0.033 0.1751 0.1751
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.0164 0.1043
Brugia malayi jmjC domain containing protein 0.0065 0.0297 0.0824
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0016 0.0031 0.0074
Loa Loa (eye worm) RecQ helicase 0.0026 0.0084 0.0233
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Schistosoma mansoni laminin gamma-3 chain 0.002 0.0056 0.014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi beta-lactamase family protein 0.0043 0.018 0.05
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0043 0.0299
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0043 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0046 0.0127
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0113 0.0564 0.1417
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0002 0.0022
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.015 0.0767 0.4896
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0016 0.0031 0.0207
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0016 0.0031 0.0207
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0016 0.0031 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0023 0.0149
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0454
Toxoplasma gondii patched family protein 0.0014 0.0018 0.0238
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0027 0.0173
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0031 0.0192
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0002 0.0005
Leishmania major hypothetical protein, conserved 0.003 0.011 0.1124
Schistosoma mansoni acetyl-CoA synthetase 0.0016 0.0031 0.0077
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0031 0.0371
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.015 0.0767 0.528
Brugia malayi Niemann-Pick C1 protein precursor 0.0223 0.1165 0.3228
Brugia malayi Animal haem peroxidase family protein 0.0063 0.0289 0.0801
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0043 0.0299
Echinococcus granulosus Niemann Pick C1 protein 0.0223 0.1165 0.2818
Schistosoma mansoni hypothetical protein 0.0014 0.0018 0.0046
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0039 0.0108
Brugia malayi hypothetical protein 0.0014 0.0018 0.0051
Schistosoma mansoni aryl hydrocarbon receptor 0.0058 0.0263 0.0662
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0036 0.0087
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0054 0.0238 0.1518
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0133 0.0321
Schistosoma mansoni hypothetical protein 0.002 0.0056 0.014
Echinococcus granulosus bloom syndrome protein 0.0026 0.0084 0.0204
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.067 0.361 0.9078
Loa Loa (eye worm) hypothetical protein 0.0113 0.0564 0.1561
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0027 0.0173
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0054 0.0238 0.1518
Brugia malayi DKFZp564C0469 protein 0.0011 0.0002 0.0005
Echinococcus multilocularis protein patched 0.0096 0.0468 0.0468
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.004 0.0164 1
Schistosoma mansoni peroxidasin 0.0063 0.0289 0.0727
Brugia malayi beta-lactamase family protein 0.0043 0.018 0.05
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0127
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0036 0.009
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.0179 0.2169
Plasmodium vivax patched family protein, putative 0.0014 0.0018 0.0924
Trypanosoma brucei pyruvate kinase 1, putative 0.004 0.0163 0.1977
Schistosoma mansoni gliotactin 0.0113 0.0564 0.1417
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0051
Brugia malayi Patched related family protein 12 0.0014 0.0018 0.0051
Onchocerca volvulus Netrin receptor homolog 0.0034 0.0129 0.0855
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0002 0.0022
Echinococcus granulosus pyruvate kinase 0.0021 0.0057 0.0137
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0071 0.0859
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.015 0.0767 0.4896
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0071 0.0449
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0046 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0239 0.1525
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0154
Schistosoma mansoni netrin receptor unc5 0.0034 0.0129 0.0325
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0027 0.0329
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0002 0.0011
Echinococcus granulosus netrin receptor unc 5 0.0034 0.0129 0.0312
Loa Loa (eye worm) hypothetical protein 0.0043 0.018 0.05
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0016 0.0031 0.0376
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0043 0.0523
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0071 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0161 0.0825 1
Brugia malayi hypothetical protein 0.0063 0.0289 0.0801
Brugia malayi jmjC domain containing protein 0.0017 0.0036 0.0099
Brugia malayi Patched related family protein 4 0.0014 0.0018 0.0051
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0036 0.2104
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0003 0.0008
Mycobacterium leprae Possible regulatory protein 0.0015 0.0027 0.0332
Echinococcus granulosus pyruvate kinase 0.004 0.0163 0.0394
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0027 0.0329
Schistosoma mansoni hypothetical protein 0.0092 0.0449 0.113
Schistosoma mansoni tar DNA-binding protein 0.0076 0.036 0.0904
Echinococcus granulosus intermediate filament protein 0.0032 0.0121 0.0293
Loa Loa (eye worm) hypothetical protein 0.0054 0.0238 0.066
Loa Loa (eye worm) hypothetical protein 0.0063 0.0289 0.0801
Loa Loa (eye worm) hypothetical protein 0.0017 0.0036 0.0099
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0046 0.0116

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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