Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine proteinase, putative | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0533 | 0.4952 | 0.4952 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0419 | 0.2818 | 0.2818 |
Trypanosoma cruzi | cysteine protease, putative | 0.0419 | 0.2818 | 0.2818 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0357 | 0.1657 | 0.1657 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0533 | 0.4952 | 0.4859 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0801 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0419 | 0.2818 | 0.2818 |
Loa Loa (eye worm) | hypothetical protein | 0.0533 | 0.4952 | 0.4952 |
Plasmodium vivax | unspecified product | 0.0419 | 0.2818 | 0.2818 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Onchocerca volvulus | Cathepsin F homolog | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0801 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0419 | 0.2818 | 0.2818 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0419 | 0.2818 | 0.2818 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0801 | 1 | 1 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0357 | 0.1657 | 0.1657 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0419 | 0.2818 | 0.2818 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0801 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0533 | 0.4952 | 0.2972 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0533 | 0.4952 | 0.4952 |
Brugia malayi | cathepsin L-like precursor | 0.0533 | 0.4952 | 0.4952 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0801 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0801 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0533 | 0.4952 | 0.4952 |
Plasmodium vivax | vivapain-2 | 0.0801 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0801 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0419 | 0.2818 | 0.2684 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0419 | 0.2818 | 0.2684 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0419 | 0.2818 | 0.2818 |
Loa Loa (eye worm) | hypothetical protein | 0.0533 | 0.4952 | 0.4952 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0801 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0357 | 0.1657 | 0.1657 |
Leishmania major | cysteine peptidase A (CPA) | 0.0801 | 1 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0801 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0357 | 0.1657 | 0.5 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0801 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0801 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0419 | 0.2818 | 0.1391 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0419 | 0.2818 | 0.2818 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0419 | 0.2818 | 0.2818 |
Loa Loa (eye worm) | fibroinase | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0801 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0801 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0801 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0419 | 0.2818 | 0.2818 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0801 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0801 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0419 | 0.2818 | 0.2818 |
Echinococcus multilocularis | cysteine protease | 0.0801 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0801 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0801 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.0533 | 0.4952 | 0.2972 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0533 | 0.4952 | 0.4952 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0533 | 0.4952 | 0.4952 |
Entamoeba histolytica | cysteine protease, putative | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0801 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0801 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0801 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0801 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0801 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0533 | 0.4952 | 0.4859 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.0419 | 0.2818 | 0.2818 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0801 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0533 | 0.4952 | 0.4952 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0801 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Onchocerca volvulus | 0.0801 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0801 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0801 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.