Detailed information for compound 841529

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 354.426 | Formula: C18H18N4O2S
  • H donors: 3 H acceptors: 2 LogP: 3.66 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C(Nc1ccc(cc1)[N+](=O)[O-])NCCc1c(C)[nH]c2c1cccc2
  • InChi: 1S/C18H18N4O2S/c1-12-15(16-4-2-3-5-17(16)20-12)10-11-19-18(25)21-13-6-8-14(9-7-13)22(23)24/h2-9,20H,10-11H2,1H3,(H2,19,21,25)
  • InChiKey: MEUOWEYBPJSEQT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0018 0.0284 0.0679
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0284 0.059
Brugia malayi nuclear receptor RXR 0.0005 0.0018 0.0043
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0018 0.0018
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0284 0.0284
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0284 0.2819
Chlamydia trachomatis acyltransferase family protein 0.0014 0.0211 0.4842
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0284 0.0295
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Schistosoma mansoni zinc finger protein 0.0005 0.0018 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0052 0.0109
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0284 0.0284
Schistosoma mansoni nuclear hormone receptor 0.001 0.0124 0.0129
Onchocerca volvulus 0.0018 0.0284 0.5734
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0124 0.0297
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0124 0.0124
Brugia malayi nuclear hormone receptor 0.001 0.0124 0.0297
Echinococcus granulosus transient receptor potential cation channel 0.0492 0.9985 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0284 0.0295
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0018 0.0019
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0014 0.0211 0.0439
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0018 0.0284 0.5734
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0124 0.0297
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0284 0.0679
Schistosoma mansoni inositol monophosphatase 0.0036 0.0658 0.0684
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0124 0.0124
Schistosoma mansoni thyroid hormone receptor 0.001 0.0124 0.0129
Brugia malayi nuclear receptor NHR-67 0.0005 0.0018 0.0043
Brugia malayi ecdysone receptor 0.0005 0.0018 0.0043
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0284 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0124 0.0297
Schistosoma mansoni amidase 0.0208 0.4175 0.4338
Echinococcus multilocularis two pore calcium channel protein 2 0.0018 0.0284 0.0284
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0284 0.0284
Echinococcus multilocularis ryanodine receptor 44f 0.0018 0.0284 0.0284
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0052 0.0109
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0025 0.0436 0.0906
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0284 0.2819
Echinococcus multilocularis short transient receptor potential channel 6 0.0018 0.0299 0.0299
Echinococcus multilocularis two pore calcium channel protein 1 0.0018 0.0284 0.0284
Brugia malayi conserved hypotetical protein 0.0005 0.0018 0.0043
Echinococcus granulosus FTZ F1 alpha 0.001 0.0124 0.0124
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0124 0.0124
Echinococcus granulosus cpg binding protein 0.003 0.0527 0.0528
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0005 0.0029 0.007
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Echinococcus multilocularis Phospholipase carboxylesterase 0.0014 0.0211 0.0211
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0014 0.0211 0.0439
Toxoplasma gondii hypothetical protein 0.0014 0.0211 0.2097
Echinococcus multilocularis nuclear receptor nhr 48 0.0005 0.0018 0.0018
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0208 0.4175 0.4175
Brugia malayi nuclear receptor NHR-88 0.0005 0.0018 0.0043
Brugia malayi hypothetical protein 0.0005 0.0029 0.007
Schistosoma mansoni transient receptor potential channel 0.0018 0.0299 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0124 0.0297
Entamoeba histolytica hypothetical protein 0.0014 0.0211 0.0439
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0124 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0018 0.0284 0.0284
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0065 0.0065
Toxoplasma gondii hypothetical protein 0.0018 0.0284 0.2819
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0124 0.0124
Brugia malayi nuclear receptor RXR 0.0005 0.0029 0.007
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0124 0.0124
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0284 0.0284
Leishmania major hypothetical protein, conserved 0.0025 0.0436 0.0906
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0124 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Schistosoma mansoni inositol monophosphatase 0.0036 0.0658 0.0684
Brugia malayi hypothetical protein 0.0005 0.0018 0.0043
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0658 0.1368
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Schistosoma mansoni fatty-acid amide hydrolase 0.0208 0.4175 0.4338
Loa Loa (eye worm) amidase 0.0025 0.0436 0.1044
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0018 0.0284 0.0284
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0005 0.0018 0.0018
Toxoplasma gondii peptidase S15, putative 0.0014 0.0211 0.2097
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0124 0.0297
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0658 0.6542
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0284 0.0284
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0658 0.1368
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0018 0.0043
Echinococcus granulosus two pore calcium channel protein 2 0.0018 0.0284 0.0284
Schistosoma mansoni nuclear receptor 0.0005 0.0018 0.0019
Schistosoma mansoni calcium-activated potassium channel 0.0018 0.0284 0.0295
Echinococcus granulosus fatty acid amide hydrolase 1 0.0208 0.4175 0.4181
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0018 0.0284 0.059
Trypanosoma cruzi monoglyceride lipase, putative 0.0239 0.481 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Brugia malayi ion channel NompC 0.0018 0.0284 0.0679
Echinococcus multilocularis muscleblind protein 1 0.0146 0.2897 0.2897
Mycobacterium ulcerans amidase 0.0025 0.0436 0.0906
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) hypothetical protein 0.0014 0.0211 0.0505
Brugia malayi steroid hormone receptor 0.001 0.0124 0.0297
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0018 0.0284 0.0284
Schistosoma mansoni voltage-dependent calcium channel 0.0018 0.0284 0.0295
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0284 0.0284
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0124 0.251
Echinococcus granulosus abhydrolase domain containing 3 0.0014 0.0211 0.0211
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0014 0.0211 0.0439
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0658 0.1368
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0284 0.0284
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.0211 0.0439
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0018 0.0284 0.0284
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0284 0.0284
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0014 0.0211 1
Mycobacterium tuberculosis Possible lysophospholipase 0.0239 0.481 1
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0018 0.0284 0.0679
Mycobacterium ulcerans hydrolase 0.0014 0.0211 0.0439
Entamoeba histolytica hypothetical protein 0.0014 0.0211 0.0439
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0018 0.0361
Echinococcus multilocularis transfer RNA-Gly 0.0018 0.0284 0.0284
Schistosoma mansoni ryanodine receptor related 0.0018 0.0284 0.0295
Echinococcus granulosus voltage gated hydrogen channel 1 0.0018 0.0284 0.0284
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0018 0.0284 0.0284
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0018 0.0019
Schistosoma mansoni peptidase 0.0014 0.0211 0.0219
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0025 0.0436 0.5
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0284 0.0284
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0284 0.0679
Onchocerca volvulus 0.001 0.0124 0.251
Echinococcus multilocularis conserved hypothetical protein 0.0018 0.0284 0.0284
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0018 0.0284 0.0284
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0014 0.0211 0.0439
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0018 0.0284 0.0679
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0005 0.0018 0.0018
Echinococcus multilocularis short transient receptor potential channel 6 0.0018 0.0284 0.0284
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0014 0.0211 0.0219
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0284 0.0284
Loa Loa (eye worm) ion channel NompC 0.0018 0.0284 0.0679
Toxoplasma gondii phospholipase/carboxylesterase 0.0014 0.0211 0.2097
Echinococcus multilocularis abhydrolase domain containing 3 0.0014 0.0211 0.0211
Loa Loa (eye worm) inositol-1 0.0036 0.0658 0.1577
Toxoplasma gondii hypothetical protein 0.0014 0.0211 0.2097
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0658 0.1368
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.481 1
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0018 0.0018
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.0284 0.0284
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0025 0.0436 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0029 0.003
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0065 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.481 1
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0025 0.0436 0.0906
Trichomonas vaginalis helicase, putative 0.0006 0.0052 0.0109
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0018 0.0284 0.0284
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.0211 0.0439
Mycobacterium ulcerans hypothetical protein 0.0239 0.481 1
Loa Loa (eye worm) voltage-dependent calcium channel 0.0018 0.0284 0.0679
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0018 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0284 0.0284
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0029 0.007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0018 0.0284 0.0679
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0124 0.0124
Echinococcus granulosus dnaJ subfamily B 0.0399 0.8065 0.8077
Mycobacterium ulcerans amidase 0.0025 0.0436 0.0906
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.0211 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Trypanosoma cruzi serine peptidase, putative 0.0014 0.0211 0.0439
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.1006 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0239 0.481 1
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0014 0.0211 0.2097
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0098 0.0234
Echinococcus granulosus thyroid hormone receptor alpha 0.0005 0.0018 0.0018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0495 0.1185
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0018 0.0018
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0005 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0211 0.0505
Mycobacterium ulcerans hypothetical protein 0.0014 0.0211 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.0284 0.0284
Leishmania major hypothetical protein, conserved 0.0018 0.0284 0.059
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.0284 0.0295
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0018 0.0019
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0284 0.0284
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0025 0.0436 0.0906
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.01 0.01
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0018 0.0284 0.0284
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0239 0.481 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0018 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0284 0.0295
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0124 0.0297
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0284 0.0284
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.01 0.01
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0239 0.481 1
Schistosoma mansoni transient receptor potential channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0124 0.0297
Mycobacterium ulcerans hypothetical protein 0.0014 0.0211 0.0439
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0052 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Schistosoma mansoni thyroid hormone receptor 0.001 0.0124 0.0129
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0124 0.0129
Echinococcus multilocularis muscleblind protein 0.0146 0.2897 0.2897
Schistosoma mansoni coup transcription factor 0.001 0.0124 0.0129
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0029 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0124 0.0124
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.8065 0.8065
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0284 0.0284
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0014 0.0211 0.0211
Echinococcus granulosus fatty acid amide hydrolase 1 0.0208 0.4175 0.4181
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0018 0.0284 0.0679
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0018 0.0018
Plasmodium falciparum lysophospholipase, putative 0.0239 0.481 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0018 0.0043
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0239 0.481 1
Schistosoma mansoni fatty-acid amide hydrolase 0.0025 0.0436 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Loa Loa (eye worm) voltage-gated calcium channel 0.0018 0.0284 0.0679
Leishmania major hypothetical protein, conserved 0.0014 0.0211 0.0439
Brugia malayi hypothetical protein 0.0005 0.0018 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Leishmania major monoglyceride lipase, putative 0.0239 0.481 1
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0025 0.0436 0.0489
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) hypothetical protein 0.0005 0.0029 0.007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0124 0.0124
Echinococcus granulosus shaker cognate 0.0018 0.0284 0.0284
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0052 0.0109
Schistosoma mansoni transient receptor potential channel 4 0.0018 0.0284 0.0295
Echinococcus granulosus fatty acid amide hydrolase 1 0.0025 0.0436 0.0436
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0014 0.0211 0.0439
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0014 0.0211 0.2097
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0124 0.0124
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0284 0.0679
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0018 0.0284 0.0284
Toxoplasma gondii hypothetical protein 0.0014 0.0211 0.2097
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0658 0.1368
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0065 0.0065
Loa Loa (eye worm) calcium channel 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0284 0.0679
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0239 0.481 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0052 0.0109
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0065 0.0068
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0124 0.0124
Plasmodium falciparum lysophospholipase, putative 0.0239 0.481 1
Schistosoma mansoni cpg binding protein 0.0028 0.0495 0.0514
Trypanosoma brucei monoglyceride lipase, putative 0.0239 0.481 1
Toxoplasma gondii hypothetical protein 0.0014 0.0211 0.2097
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0018 0.0284 0.0295
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0124 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Toxoplasma gondii protein c14orf29, putative 0.0014 0.0211 0.2097
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0658 0.1368
Echinococcus multilocularis transient receptor potential gamma protein 0.0018 0.0284 0.0284
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0052 0.0109
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0284 0.0295
Schistosoma mansoni voltage-gated cation channel 0.0018 0.0284 0.0295
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0014 0.0211 0.0439
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0284 0.0679
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0025 0.0436 0.0436
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Loa Loa (eye worm) hypothetical protein 0.0146 0.2897 0.6938
Schistosoma mansoni cpg binding protein 0.003 0.0527 0.0548
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0014 0.0211 0.0439
Echinococcus multilocularis voltage dependent calcium channel 0.0018 0.0284 0.0284
Plasmodium falciparum esterase, putative 0.0239 0.481 1
Schistosoma mansoni vesicular amine transporter 0.0018 0.0284 0.0295
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0018 0.0018
Brugia malayi nuclear hormone receptor 0.0005 0.0018 0.0043
Echinococcus granulosus voltage dependent calcium channel 0.0018 0.0284 0.0284
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0658 0.1368
Mycobacterium ulcerans lysophospholipase 0.0239 0.481 1
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0025 0.0436 0.0906
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0018 0.0284 0.0679
Plasmodium vivax PST-A protein 0.0239 0.481 1
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0005 0.0029 0.007
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0284 0.0284
Echinococcus granulosus hypothetical protein 0.0018 0.0284 0.0284
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0284 0.0284
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0018 0.0284 0.0284
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0284 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0124 0.0124
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0018 0.0284 0.059
Brugia malayi Cyclic-nucleotide gated cation channel 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.0208 0.4175 1
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0284 0.2819
Loa Loa (eye worm) amidase 0.0025 0.0436 0.1044
Onchocerca volvulus 0.0028 0.0495 1
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0018 0.0284 0.0295
Brugia malayi Amidase family protein 0.0025 0.0436 0.1044
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0124 0.0297
Mycobacterium ulcerans amidase 0.0025 0.0436 0.0906
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.0211 0.0439
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0124 0.0297
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0018 0.0284 0.059
Brugia malayi Muscleblind-like protein 0.0146 0.2897 0.6938
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0004 0.0005 0.0005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0284 0.0284
Brugia malayi hypothetical protein 0.0005 0.0029 0.007
Schistosoma mansoni cpg binding protein 0.003 0.0527 0.0548
Brugia malayi MGC83647 protein 0.0014 0.0211 0.0505
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0018 0.0043
Leishmania major hypothetical protein, conserved 0.0014 0.0211 0.0439
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0029 0.0029
Echinococcus granulosus abhydrolase domain containing protein 13 0.0014 0.0211 0.0211
Echinococcus granulosus TRP transient receptor potential channel 0.0018 0.0284 0.0284
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0124 0.251
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0124 0.0129
Echinococcus granulosus potassium large conductance calcium activated 0.0018 0.0284 0.0284
Echinococcus multilocularis shaker cognate 0.0018 0.0284 0.0284
Echinococcus granulosus ankyrin repeat protein 0.0475 0.9624 0.9639
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0025 0.0436 0.0906
Brugia malayi Inositol-1 0.0036 0.0658 0.1577
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Brugia malayi Protein C20orf22 0.0014 0.0211 0.0505
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0475 0.9624 1
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0124 0.0129
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0018 0.0284 0.0284
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0018 0.0284 0.0679
Brugia malayi Transient-receptor-potential like protein 0.0018 0.0284 0.0679
Loa Loa (eye worm) histone methyltransferase 0.0009 0.01 0.0239
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Echinococcus granulosus muscleblind protein 0.0146 0.2897 0.2901
Mycobacterium ulcerans peptide amidase, GatA 0.0025 0.0436 0.0906
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0284 0.0284
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0284 0.0284
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0018 0.0284 0.0295
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Echinococcus granulosus sodium channel protein 0.0018 0.0284 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0124 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0124 0.0297
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0284 0.0284
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0284 0.0295
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0284 0.2819
Trypanosoma cruzi amidase, putative 0.0025 0.0436 0.0906
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0018 0.0284 0.0295
Brugia malayi olfactory channel protein osm-9 0.0018 0.0299 0.0715
Schistosoma mansoni nuclear receptor 0.0005 0.0018 0.0019
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0124 0.0297
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0284 0.059
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0299 0.0299
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0018 0.0284 0.059
Brugia malayi MGC79044 protein 0.0014 0.0211 0.0505
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0018 0.0043
Schistosoma mansoni hypothetical protein 0.0018 0.0284 0.0295
Schistosoma mansoni transient receptor potential channel 0.0018 0.0284 0.0295
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0018 0.0284 0.0284
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0018 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0124 0.0297
Echinococcus multilocularis potassium large conductance calcium activated 0.0018 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0025 0.0436 0.0906
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0025 0.0436 0.0436
Brugia malayi Amidase family protein 0.0025 0.0436 0.1044
Echinococcus granulosus calcium activated potassium channel 0.0018 0.0284 0.0284
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0124 0.251
Brugia malayi putative amidase 0.0025 0.0436 0.1044
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0124 0.0124
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0658 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0284 0.0284
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0018 0.0361
Brugia malayi nuclear receptor NHR-88 0.001 0.0124 0.0297
Echinococcus multilocularis voltage dependent calcium channel 0.0018 0.0284 0.0284
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0581 0.1208
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0239 0.481 1
Leishmania major hypothetical protein, unknown function 0.0018 0.0284 0.059
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0284 0.0284
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0029 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1136 0.118
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0124 0.0297
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0018 0.0019
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0018 0.0043
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0018 0.0019
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0018 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0124 0.0297
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0014 0.0211 0.0211
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Loa Loa (eye worm) hypothetical protein 0.0146 0.2897 0.6938
Brugia malayi voltage-dependent calcium channel 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.0005 0.0029 0.007
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0052 0.0109
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0284 0.0284
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0284 0.0295
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0284 0.0679
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0025 0.0436 0.0906
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0124 0.0129
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0018 0.0043
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Echinococcus granulosus nuclear receptor nhr 48 0.0005 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0005 0.0029 0.007
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0025 0.0436 0.0436
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0284 0.2819
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0018 0.0284 0.5734
Brugia malayi cation channel family protein 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.0018 0.0299 0.0715
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0124 0.0297
Trypanosoma brucei monoglyceride lipase, putative 0.0239 0.481 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0124 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0658 0.0658
Entamoeba histolytica ;Alias 0.0014 0.0211 0.0439
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0658 0.0659
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0658 0.1368
Brugia malayi CXXC zinc finger family protein 0.0028 0.0495 0.1185
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0014 0.0211 0.0439
Onchocerca volvulus 0.0005 0.0018 0.0361
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0284 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Onchocerca volvulus 0.0005 0.0018 0.0361
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0284 0.0284
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0124 0.0124
Brugia malayi ecdysteroid receptor 0.001 0.0124 0.0297
Echinococcus granulosus ryanodine receptor 44f 0.0018 0.0284 0.0284
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0018 0.0284 0.0679
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) hypothetical protein 0.0014 0.0211 0.0505
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0239 0.481 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0124 0.0297
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0025 0.0436 0.0453
Echinococcus multilocularis ankyrin repeat protein 0.0475 0.9624 0.9624
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0124 0.0124
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0025 0.0436 0.0489
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0025 0.0436 0.0906
Echinococcus granulosus two pore calcium channel protein 1 0.0018 0.0284 0.0284
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0018 0.0284 0.0284
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0014 0.0211 0.0219
Schistosoma mansoni voltage-gated ion channel 0.0018 0.0284 0.0295
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0029 0.007
Toxoplasma gondii hypothetical protein 0.0018 0.0284 0.2819
Mycobacterium ulcerans amidase 0.0025 0.0436 0.0906
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0284 0.0284
Brugia malayi tailless protein 0.0005 0.0018 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0124 0.0297
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0581 0.1208
Chlamydia trachomatis hydrolase 0.0014 0.0211 0.4842
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0124 0.0297
Loa Loa (eye worm) DR-78 0.0005 0.0018 0.0043
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0018 0.0284 0.0679
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0052 0.0109
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0018 0.0284 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0124 0.0129
Schistosoma mansoni two-pore calcium channel 0.0018 0.0284 0.0295
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0014 0.0211 0.0439
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0018 0.0284 0.059
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0018 0.0284 0.0284
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0284 0.0295
Mycobacterium ulcerans amidase 0.0025 0.0436 0.0906
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0018 0.0284 0.0295
Brugia malayi amidase 0.0208 0.4175 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0658 0.1368
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0065 0.0065
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0124 0.0129
Echinococcus multilocularis sodium leak channel non selective protein 0.0018 0.0284 0.0284
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0284 0.0284
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0299 0.0299
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0211 0.0439
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0284 0.0284
Echinococcus granulosus voltage dependent calcium channel 0.0018 0.0284 0.0284
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0124 0.0297
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0284 0.0284
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0284 0.0284
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0124 0.0129
Echinococcus granulosus sodium leak channel non selective protein 0.0018 0.0284 0.0284
Echinococcus multilocularis sodium channel protein 0.0018 0.0284 0.0284
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0284 0.0284
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0284 0.0295
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0284 0.0295
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0239 0.481 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0018 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0124 0.0297
Echinococcus granulosus Phospholipase carboxylesterase 0.0014 0.0211 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0124 0.0297
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0014 0.0211 0.0505
Echinococcus granulosus short transient receptor potential channel 6 0.0018 0.0299 0.0299
Echinococcus granulosus short transient receptor potential channel 6 0.0018 0.0284 0.0284
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0124 0.0124
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0124 0.0124
Trypanosoma cruzi amidase, putative 0.0025 0.0436 0.0906
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0018 0.0284 0.0284
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0284 0.0284
Echinococcus multilocularis cpg binding protein 0.003 0.0527 0.0527
Loa Loa (eye worm) hypothetical protein 0.0018 0.0284 0.0679
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0014 0.0211 0.0439
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0284 0.0284
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0014 0.0211 0.2097
Loa Loa (eye worm) ryanodine receptor 0.0018 0.0284 0.0679
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0208 0.4175 0.4175
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0018 0.0284 0.0284
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0284 0.0284
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0124 0.0297
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0284 0.0679
Loa Loa (eye worm) hypothetical protein 0.0014 0.0211 0.0505
Plasmodium falciparum lysophospholipase, putative 0.0239 0.481 1
Trypanosoma cruzi serine peptidase, putative 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0124 0.0297
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0018 0.0284 0.0284
Toxoplasma gondii phospholipase 0.0014 0.0211 0.2097
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0018 0.0284 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0239 0.481 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.0109
Schistosoma mansoni hypothetical protein 0.0399 0.8065 0.838
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0284 0.0284
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0018 0.0284 0.0679
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0014 0.0211 0.0439
Loa Loa (eye worm) hypothetical protein 0.0005 0.0018 0.0043
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0018 0.0284 0.0679
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0018 0.0043
Echinococcus granulosus transient receptor potential gamma protein 0.0018 0.0284 0.0284
Brugia malayi cation channel family protein 0.0018 0.0284 0.0679
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0025 0.0436 0.0906

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.