Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Echinococcus multilocularis | geminin | 0.0167 | 0.3452 | 0.3452 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.3452 | 0.3452 |
Brugia malayi | Carboxylesterase family protein | 0.0074 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Brugia malayi | Carboxylesterase family protein | 0.0074 | 0.1197 | 0.1197 |
Echinococcus multilocularis | acetylcholinesterase | 0.0437 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0437 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | carboxylesterase | 0.0074 | 0.1197 | 0.1197 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0074 | 0.1197 | 0.1197 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0074 | 0.1197 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0437 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0074 | 0.1197 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Onchocerca volvulus | 0.0074 | 0.1197 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Brugia malayi | Carboxylesterase family protein | 0.0074 | 0.1197 | 0.1197 |
Brugia malayi | Carboxylesterase family protein | 0.0437 | 1 | 1 |
Onchocerca volvulus | 0.0074 | 0.1197 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0437 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Schistosoma mansoni | gliotactin | 0.0074 | 0.1197 | 0.1197 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0074 | 0.1197 | 0.1197 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0074 | 0.1197 | 0.1197 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0074 | 0.1197 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.3452 | 0.3452 |
Echinococcus multilocularis | neuroligin | 0.0074 | 0.1197 | 0.1197 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0437 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0437 | 1 | 1 |
Onchocerca volvulus | 0.0074 | 0.1197 | 0.5 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0074 | 0.1197 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0074 | 0.1197 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0437 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0074 | 0.1197 | 0.1197 |
Onchocerca volvulus | 0.0074 | 0.1197 | 0.5 | |
Schistosoma mansoni | acetylcholinesterase | 0.0074 | 0.1197 | 0.1197 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0074 | 0.1197 | 0.1197 |
Onchocerca volvulus | 0.0074 | 0.1197 | 0.5 | |
Echinococcus granulosus | neuroligin | 0.0074 | 0.1197 | 0.1197 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0074 | 0.1197 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1197 | 0.1197 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0074 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.0437 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0437 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0074 | 0.1197 | 0.1197 |
Echinococcus granulosus | acetylcholinesterase | 0.0437 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0437 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0167 | 0.3452 | 0.3452 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.