Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0037 | 0.1801 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0541 | 0.2559 |
Echinococcus multilocularis | musashi | 0.0027 | 0.1048 | 0.1048 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0541 | 0.0638 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0037 | 0.1801 | 0.1332 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0541 | 0.0541 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0541 | 0.2559 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.1801 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0541 | 0.0638 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0541 | 0.2559 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0037 | 0.1801 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0541 | 0.0541 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0037 | 0.1801 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.1048 | 0.0537 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0541 | 0.2559 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0541 | 0.2559 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0541 | 0.2559 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0541 | 0.0541 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0541 | 0.2559 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 0.8481 | 0.8394 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0037 | 0.1801 | 0.5 |
Onchocerca volvulus | 0.0027 | 0.1048 | 1 | |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.1801 | 0.5 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0037 | 0.1801 | 0.2123 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0541 | 0.2559 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0541 | 0.3004 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.1801 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0541 | 0.3004 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.1801 | 0.2123 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0541 | 0.0638 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.1048 | 0.5557 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0541 | 0.2559 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0541 | 0.0541 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.1048 | 0.1236 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.1801 | 0.1801 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.1048 | 0.1048 |
Onchocerca volvulus | 0.0027 | 0.1048 | 1 | |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0541 | 0.2559 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0541 | 0.3004 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0541 | 0.0541 |
Echinococcus multilocularis | lamin | 0.0027 | 0.1048 | 0.1048 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0541 | 0.0638 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0541 | 0.2559 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.1801 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.1801 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0541 | 0.0541 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0541 | 0.2559 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0541 | 0.2559 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0541 | 0.3004 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0541 | 0.2559 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0541 | 0.2559 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0037 | 0.1801 | 0.1332 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0541 | 0.3004 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0541 | 0.0541 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.1801 | 0.5 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0127 | 0.8481 | 0.8481 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.1048 | 0.5822 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0541 | 0.2559 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.1048 | 0.5822 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0127 | 0.8481 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Schistosoma mansoni | lamin | 0.0027 | 0.1048 | 0.0537 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1048 | 0.5822 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0541 | 0.2559 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.1048 | 0.1236 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 1 | 1 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.1801 | 0.1801 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0108 | 0.0598 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0541 | 0.0638 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0541 | 0.3004 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.1048 | 0.5557 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0541 | 0.0638 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0541 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.5616 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0541 | 0.0638 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0037 | 0.1801 | 0.1801 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0541 | 0.2559 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0541 | 0.2559 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0541 | 0.2559 |
Echinococcus granulosus | lamin | 0.0027 | 0.1048 | 0.1236 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0541 | 0.3004 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0541 | 0.0638 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0541 | 0.3004 |
Schistosoma mansoni | lamin | 0.0027 | 0.1048 | 0.0537 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.1801 | 0.2123 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0541 | 0.3004 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1801 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.