Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | thyroid hormone receptor | 0.0258 | 0.3833 | 0.3833 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0239 | 0.3525 | 0.3525 |
Echinococcus multilocularis | tumor protein p63 | 0.0329 | 0.4976 | 0.4976 |
Schistosoma mansoni | thyroid hormone receptor | 0.0258 | 0.3833 | 0.3833 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0258 | 0.3833 | 0.3833 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0239 | 0.3525 | 0.3525 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0643 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0019 | 0 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0019 | 0 | 0.5 |
Onchocerca volvulus | 0.0048 | 0.0466 | 1 | |
Echinococcus granulosus | tumor protein p63 | 0.0329 | 0.4976 | 0.4976 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0239 | 0.3525 | 0.3525 |
Brugia malayi | ecdysteroid receptor | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0466 | 0.0466 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0019 | 0 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0643 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0019 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0019 | 0 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0019 | 0 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0466 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0019 | 0 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0019 | 0 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0019 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.