Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | set domain proteins, putative | 0.0266 | 0.8546 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0966 | 0.218 |
Schistosoma mansoni | thyroid hormone receptor | 0.0174 | 0.528 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0295 | 0.9552 | 0.995 |
Onchocerca volvulus | 0.0266 | 0.8546 | 1 | |
Brugia malayi | Pre-SET motif family protein | 0.0234 | 0.7406 | 0.7406 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0234 | 0.7406 | 0.7714 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0296 | 0.96 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0336 | 0.035 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0966 | 0.1007 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0336 | 0.0637 |
Schistosoma mansoni | hypothetical protein | 0.015 | 0.4432 | 0.8394 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.015 | 0.4432 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0296 | 0.96 | 0.96 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0336 | 0.0637 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0174 | 0.528 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0336 | 0.0336 |
Schistosoma mansoni | thyroid hormone receptor | 0.0174 | 0.528 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0966 | 0.0966 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0966 | 0.183 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0966 | 0.218 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0336 | 0.5 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0336 | 0.0637 |
Onchocerca volvulus | 0.0034 | 0.0336 | 0.0393 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0966 | 0.183 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0296 | 0.96 | 0.96 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0966 | 0.183 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0293 | 0.066 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0336 | 0.0637 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0966 | 0.183 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0336 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0336 | 0.0758 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.015 | 0.4432 | 0.8394 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0336 | 0.0637 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0336 | 0.0637 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0966 | 0.183 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.