Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0044 | 0.0346 | 0.0834 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.3732 | 0.9009 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0044 | 0.0346 | 0.0346 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0078 | 0.1385 | 0.3342 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0078 | 0.1385 | 0.3342 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.2733 | 0.6595 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.271 | 0.271 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0044 | 0.0346 | 0.1223 |
Brugia malayi | Hr1 repeat family protein | 0.0044 | 0.0346 | 0.1223 |
Schistosoma mansoni | unc-13 (munc13) | 0.0034 | 0.0039 | 0.0095 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0034 | 0.0039 | 0.0095 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0091 | 0.1758 | 0.4244 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0078 | 0.1385 | 0.3342 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0044 | 0.0346 | 0.0834 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Toxoplasma gondii | AGC kinase | 0.0044 | 0.0346 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.8654 | 0.8654 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0078 | 0.1385 | 0.1385 |
Echinococcus multilocularis | protein kinase c iota type | 0.0076 | 0.1297 | 0.313 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0034 | 0.0039 | 0.0095 |
Brugia malayi | Protein kinase domain containing protein | 0.0044 | 0.0346 | 0.1223 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1758 | 0.1758 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0044 | 0.0346 | 0.0346 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0169 | 0.4143 | 1 |
Onchocerca volvulus | 0.0318 | 0.8654 | 1 | |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0044 | 0.0346 | 0.0834 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0169 | 0.4143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.9606 | 0.9606 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0044 | 0.0346 | 0.0834 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0346 | 0.0834 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0095 | 0.1875 | 0.1875 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0044 | 0.0346 | 0.0346 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0044 | 0.0346 | 0.0346 |
Brugia malayi | Protein kinase c protein 2 | 0.0126 | 0.2827 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0169 | 0.4143 | 1 |
Schistosoma mansoni | serine/threonine kinase | 0.0044 | 0.0346 | 0.0834 |
Onchocerca volvulus | 0.0034 | 0.0039 | 0.0045 | |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0091 | 0.1758 | 0.4244 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0138 | 0.3192 | 0.7704 |
Echinococcus granulosus | unc 13 munc13 | 0.0034 | 0.0039 | 0.0095 |
Brugia malayi | Protein kinase domain containing protein | 0.0044 | 0.0346 | 0.1223 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0044 | 0.0346 | 0.0834 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0044 | 0.0346 | 0.0834 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0044 | 0.0346 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.8654 | 0.8654 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0044 | 0.0346 | 0.0346 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0044 | 0.0346 | 0.0834 |
Brugia malayi | protein kinase C II. | 0.0078 | 0.1385 | 0.4899 |
Schistosoma mansoni | protein kinase C | 0.0034 | 0.0039 | 0.0095 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0076 | 0.1297 | 0.313 |
Echinococcus granulosus | protein kinase C gamma type | 0.0138 | 0.3192 | 0.7704 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0034 | 0.0039 | 0.0095 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0346 | 0.0834 |
Entamoeba histolytica | protein kinase, putative | 0.0044 | 0.0346 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0346 | 0.0834 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0091 | 0.1758 | 0.4244 |
Schistosoma mansoni | unc-13 (munc13) | 0.0034 | 0.0039 | 0.0095 |
Entamoeba histolytica | protein kinase, putative | 0.0044 | 0.0346 | 0.5 |
Schistosoma mansoni | atypical protein kinase C | 0.0076 | 0.1297 | 0.313 |
Entamoeba histolytica | protein kinase, putative | 0.0044 | 0.0346 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0044 | 0.0346 | 0.5 |
Echinococcus granulosus | NDR protein kinase | 0.0044 | 0.0346 | 0.0834 |
Brugia malayi | Protein kinase domain containing protein | 0.0044 | 0.0346 | 0.1223 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.2733 | 0.6595 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.8654 | 0.8654 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0169 | 0.4143 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0044 | 0.0346 | 0.0834 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.3732 | 0.9009 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0044 | 0.0346 | 0.0834 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.2733 | 0.6595 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0044 | 0.0346 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0156 | 0.3732 | 0.9009 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0044 | 0.0346 | 0.0346 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0346 | 0.0834 |
Trichomonas vaginalis | AGC family protein kinase | 0.0044 | 0.0346 | 1 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0044 | 0.0346 | 0.0346 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.