Detailed information for compound 844214

Basic information

Technical information
  • TDR Targets ID: 844214
  • Name: N-(2-fluorophenyl)-2-(4-oxopyrrolo[2,1-c]quin oxalin-5-yl)acetamide
  • MW: 335.332 | Formula: C19H14FN3O2
  • H donors: 1 H acceptors: 2 LogP: 2.75 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Cn1c(=O)c2cccn2c2c1cccc2)Nc1ccccc1F
  • InChi: 1S/C19H14FN3O2/c20-13-6-1-2-7-14(13)21-18(24)12-23-16-9-4-3-8-15(16)22-11-5-10-17(22)19(23)25/h1-11H,12H2,(H,21,24)
  • InChiKey: MKZOJEMXRIRNFI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-fluorophenyl)-2-(4-oxo-5-pyrrolo[2,1-c]quinoxalinyl)acetamide
  • N-(2-fluorophenyl)-2-(4-ketopyrrolo[2,1-c]quinoxalin-5-yl)acetamide
  • N-(2-fluorophenyl)-2-(4-oxopyrrolo[2,1-c]quinoxalin-5-yl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis 0.1295 0.2398 0.2398
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0114 0.0311
Loa Loa (eye worm) G-protein coupled receptor 0.0314 0.0472 0.1292
Plasmodium falciparum protein kinase 5 0.0144 0.0136 0.3659
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0083 0.0018 0.5
Echinococcus granulosus membrane bound transcription factor site 1 0.0083 0.0018 0.0018
Echinococcus multilocularis neuropeptide s receptor 0.0314 0.0472 0.0472
Echinococcus granulosus beta tubulin 0.0249 0.0342 0.0342
Echinococcus multilocularis inhibitor of apoptosis protein 0.0132 0.0114 0.0114
Schistosoma mansoni neuropeptide f receptor 76f 0.0314 0.0472 0.0472
Schistosoma mansoni growth hormone secretagogue receptor 0.0314 0.0472 0.0472
Trypanosoma cruzi CYC2-like cyclin, putative 0.0408 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0811 0.1448 0.3967
Toxoplasma gondii hypothetical protein 0.0145 0.0138 0.2967
Leishmania major hypothetical protein, conserved 0.0209 0.0264 0.3856
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0424 0.0687 0.4133
Echinococcus multilocularis tubulin subunit beta 0.0249 0.0342 0.0342
Schistosoma mansoni adenoreceptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0515 0.0866 0.2372
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Giardia lamblia Beta tubulin 0.0249 0.0342 0.3449
Trichomonas vaginalis cyclin D, putative 0.019 0.0228 0.13
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus granulosus g-protein coupled receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0144 0.0136 0.0374
Echinococcus granulosus cyclins 0.019 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus granulosus tm gpcr rhodopsin 0.2362 0.4492 0.4492
Echinococcus granulosus cyclin dependent kinase 1 0.0144 0.0136 0.0136
Brugia malayi Tachykinin-like peptides receptor 99D 0.1932 0.3649 1
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Brugia malayi Kringle domain containing protein 0.0209 0.0264 0.0723
Echinococcus granulosus cyclin B 0.0408 0.0656 0.0656
Toxoplasma gondii beta tubulin 0.0249 0.0342 0.8006
Schistosoma mansoni histamine h1 receptor 0.0314 0.0472 0.0472
Echinococcus granulosus hypothetical protein 0.0314 0.0472 0.0472
Trichomonas vaginalis tubulin beta chain, putative 0.0249 0.0342 0.2004
Onchocerca volvulus 0.0209 0.0264 0.3049
Echinococcus granulosus Furin 1 0.0507 0.085 0.085
Brugia malayi cell division control protein 2 homolog 0.0144 0.0136 0.0374
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0908 0.1637 1
Onchocerca volvulus 0.0314 0.0472 0.5447
Loa Loa (eye worm) hypothetical protein 0.0408 0.0656 0.1798
Trichomonas vaginalis cyclin B, putative 0.019 0.0228 0.13
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni neuropeptide F-like receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0908 0.1637 0.1637
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus multilocularis cyclin B 0.0408 0.0656 0.0656
Trypanosoma cruzi cdc2-related kinase 1 0.0144 0.0136 0.1859
Loa Loa (eye worm) BEN-1 protein 0.0249 0.0342 0.0938
Giardia lamblia Hypothetical protein 0.019 0.0228 0.1539
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0109 0.0068 0.0068
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0314 0.0472 0.1292
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Trypanosoma brucei beta tubulin 0.0249 0.0342 0.5082
Loa Loa (eye worm) hypothetical protein 0.1932 0.3649 1
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Plasmodium falciparum cysteine repeat modular protein 1 0.0209 0.0264 0.7588
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0314 0.0472 0.1292
Brugia malayi Peptidase family M1 containing protein 0.0118 0.0086 0.0234
Echinococcus multilocularis cyclin b3 0.019 0.0228 0.0228
Echinococcus granulosus Tubulin beta 2C chain 0.0249 0.0342 0.0342
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0314 0.0472 0.1292
Echinococcus multilocularis Tubulin beta 2C chain 0.0249 0.0342 0.0342
Echinococcus granulosus cyclin B3 1 0.019 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0132 0.0114 0.0311
Echinococcus multilocularis g protein coupled receptor 0.0314 0.0472 0.0472
Brugia malayi endoprotease bli-4 precursor 0.1672 0.3138 0.8599
Trypanosoma brucei RNA helicase, putative 0.0111 0.0072 0.0847
Schistosoma mansoni site-1 peptidase (S08 family) 0.0083 0.0018 0.0018
Trichomonas vaginalis cyclins, putative 0.0408 0.0656 0.3944
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Trypanosoma brucei mitotic cyclin 6 0.0408 0.0656 1
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0083 0.0018 0.5
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.019 0.0228 0.0228
Trypanosoma cruzi beta tubulin, putative 0.0249 0.0342 0.5082
Echinococcus granulosus tubulin beta 1 chain 0.0249 0.0342 0.0342
Loa Loa (eye worm) peptidase family M1 containing protein 0.0095 0.0041 0.0113
Onchocerca volvulus 0.0314 0.0472 0.5447
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0114 0.0311
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus multilocularis g protein coupled receptor 0.0314 0.0472 0.0472
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0314 0.0472 0.0472
Onchocerca volvulus 0.0132 0.0114 0.1313
Schistosoma mansoni cyclin B 0.0408 0.0656 0.0656
Echinococcus granulosus sex peptide receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0908 0.1637 1
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Brugia malayi Serotonin receptor 0.0314 0.0472 0.1292
Loa Loa (eye worm) endoprotease bli-4 0.1672 0.3138 0.8599
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Trypanosoma brucei beta tubulin 0.0249 0.0342 0.5082
Loa Loa (eye worm) hypothetical protein 0.0408 0.0656 0.1798
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0314 0.0472 0.0472
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0314 0.0472 0.0472
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0209 0.0264 0.0723
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus multilocularis Furin 1 0.0507 0.085 0.085
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0377 0.0594 0.3561
Echinococcus granulosus alpha 1A adrenergic receptor 0.0314 0.0472 0.0472
Schistosoma mansoni hypothetical protein 0.0314 0.0472 0.0472
Echinococcus multilocularis Tubulin beta 2C chain 0.0249 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Onchocerca volvulus 0.0314 0.0472 0.5447
Onchocerca volvulus 0.0314 0.0472 0.5447
Brugia malayi Serotonin receptor 0.0314 0.0472 0.1292
Onchocerca volvulus 0.0314 0.0472 0.5447
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) subtilase 0.0083 0.0018 0.0049
Echinococcus granulosus g protein coupled receptor 0.0314 0.0472 0.0472
Echinococcus granulosus g protein coupled receptor 0.0314 0.0472 0.0472
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0314 0.0472 0.1292
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0106 0.0062 0.0169
Echinococcus multilocularis neuropeptide receptor A26 0.0314 0.0472 0.0472
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Trichomonas vaginalis cyclin D, putative 0.019 0.0228 0.13
Onchocerca volvulus 0.0314 0.0472 0.5447
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Trichomonas vaginalis cyclin B, putative 0.0408 0.0656 0.3944
Loa Loa (eye worm) TYRA-2 protein 0.0314 0.0472 0.1292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Echinococcus multilocularis neuropeptides capa receptor 0.0314 0.0472 0.0472
Brugia malayi ORL1-like opioid receptor 0.0314 0.0472 0.1292
Giardia lamblia G2/mitotic-specific cyclin B 0.0408 0.0656 0.8712
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0507 0.085 0.5143
Onchocerca volvulus 0.0314 0.0472 0.5447
Brugia malayi Cyclin, N-terminal domain containing protein 0.0408 0.0656 0.1798
Loa Loa (eye worm) hypothetical protein 0.0345 0.0531 0.1456
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1672 0.3138 0.3138
Brugia malayi proprotein convertase 2 0.1272 0.2352 0.6444
Entamoeba histolytica cyclin, putative 0.019 0.0228 0.1766
Echinococcus granulosus tm gpcr rhodopsin 0.0314 0.0472 0.0472
Loa Loa (eye worm) proprotein convertase 2 0.0507 0.085 0.233
Echinococcus granulosus tm gpcr rhodopsin 0.0314 0.0472 0.0472
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus granulosus somatostatin receptor 0.0314 0.0472 0.0472
Schistosoma mansoni opsin-like receptor 0.0314 0.0472 0.0472
Schistosoma mansoni neuropeptide F-like receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0507 0.085 0.5143
Loa Loa (eye worm) neuropeptide F receptor 0.0314 0.0472 0.1292
Schistosoma mansoni neuropeptide receptor 0.0314 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0136 0.0136
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Schistosoma mansoni neuropeptide receptor 0.0472 0.0781 0.0781
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Entamoeba histolytica cyclin, putative 0.0408 0.0656 1
Echinococcus granulosus cyclin dependent kinase 0.0144 0.0136 0.0136
Trichomonas vaginalis tubulin, putative 0.0249 0.0342 0.2004
Onchocerca volvulus 0.0314 0.0472 0.5447
Schistosoma mansoni tubulin subunit beta 0.0249 0.0342 0.0342
Echinococcus multilocularis dnaJ subfamily B 0.5166 1 1
Brugia malayi G-protein coupled receptor 0.0314 0.0472 0.1292
Echinococcus multilocularis g-protein coupled receptor 0.0314 0.0472 0.0472
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0908 0.1637 0.1637
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0144 0.0136 0.2929
Brugia malayi Dopamine receptor protein 2 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0136 0.0733
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni amine GPCR 0.0314 0.0472 0.0472
Schistosoma mansoni hypothetical protein 0.0314 0.0472 0.0472
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0314 0.0472 0.0472
Entamoeba histolytica cyclin family protein 0.019 0.0228 0.1766
Echinococcus granulosus dro:myosuppressin receptor 0.0314 0.0472 0.0472
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0132 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0515 0.0866 0.2372
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0083 0.0017 0.0048
Echinococcus granulosus neuropeptide FF receptor 2 0.1932 0.3649 0.3649
Echinococcus multilocularis serotonin receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0083 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0111 0.0072 0.0072
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0314 0.0472 0.0472
Schistosoma mansoni myosin xvIII 0.0314 0.0472 0.0472
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.013 0.011 0.011
Schistosoma mansoni site-1 peptidase (S08 family) 0.0083 0.0018 0.0018
Brugia malayi Subtilase family protein 0.0083 0.0018 0.0049
Onchocerca volvulus 0.0078 0.0008 0.0091
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Toxoplasma gondii PAN domain-containing protein 0.029 0.0423 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis tubulin beta 1 chain 0.0249 0.0342 0.0342
Loa Loa (eye worm) beta-tubulin 0.0249 0.0342 0.0938
Brugia malayi Tubulin beta-1 chain 0.0249 0.0342 0.0938
Brugia malayi Protein kinase domain containing protein 0.0144 0.0136 0.0374
Echinococcus multilocularis allatostatin A receptor 0.0314 0.0472 0.0472
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0144 0.0136 0.0136
Echinococcus multilocularis epidermal growth factor receptor 0.0247 0.0339 0.0339
Brugia malayi Trypsin family protein 0.0515 0.0866 0.2372
Echinococcus multilocularis G protein coupled receptor 139 0.0472 0.0781 0.0781
Onchocerca volvulus Neuropeptide F receptor homolog 0.0314 0.0472 0.5447
Trichomonas vaginalis hypothetical protein 0.0377 0.0594 0.3561
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Echinococcus granulosus peptide allatostatin:somatostatin 0.0314 0.0472 0.0472
Echinococcus granulosus 7tm_1 domain containing protein 0.0314 0.0472 0.0472
Echinococcus granulosus aminopeptidase N 0.0118 0.0086 0.0086
Trichomonas vaginalis cyclin B, putative 0.0408 0.0656 0.3944
Schistosoma mansoni tubulin subunit beta 0.0249 0.0342 0.0342
Loa Loa (eye worm) tubulin beta-1 chain 0.0249 0.0342 0.0938
Echinococcus multilocularis beta tubulin 0.0249 0.0342 0.0342
Trypanosoma cruzi cyclin, putative 0.0408 0.0656 1
Echinococcus granulosus epidermal growth factor receptor 0.0247 0.0339 0.0339
Echinococcus multilocularis cyclin dependent kinase 1 0.0144 0.0136 0.0136
Loa Loa (eye worm) BEN-1 protein 0.0249 0.0342 0.0938
Giardia lamblia Furin precursor putative serine protease 0.0424 0.0687 0.9225
Schistosoma mansoni hypothetical protein 0.5166 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0314 0.0472 0.0472
Brugia malayi Furin-like cysteine rich region family protein 0.0247 0.0339 0.093
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0083 0.0018 0.0049
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis neuropeptide receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis fmrfamide receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) tubulin beta chain 0.0249 0.0342 0.0938
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Brugia malayi neuroendocrine convertase 1 precursor 0.1569 0.2936 0.8046
Loa Loa (eye worm) tubulin beta-2A chain 0.0249 0.0342 0.0938
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.013 0.011 0.0571
Brugia malayi celfurPC protein 0.1295 0.2398 0.657
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0314 0.0472 0.0472
Echinococcus granulosus neuropeptide receptor 0.0472 0.0781 0.0781
Echinococcus multilocularis neuroendocrine convertase 2 0.1272 0.2352 0.2352
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Brugia malayi larval opioid receptor 0.0314 0.0472 0.1292
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0144 0.0136 0.0374
Schistosoma mansoni hypothetical protein 0.0314 0.0472 0.0472
Schistosoma mansoni amine GPCR 0.0314 0.0472 0.0472
Trichomonas vaginalis cyclins, putative 0.0264 0.0372 0.2191
Echinococcus multilocularis Tubulin beta 2C chain 0.0249 0.0342 0.0342
Echinococcus granulosus neuropeptide receptor A26 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Trypanosoma cruzi cdc2-related kinase 1 0.0144 0.0136 0.1859
Schistosoma mansoni biogenic amine (5HT) receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Echinococcus multilocularis G-protein coupled receptor, putative 0.0314 0.0472 0.0472
Trichomonas vaginalis cyclin B3, putative 0.019 0.0228 0.13
Onchocerca volvulus 0.0408 0.0656 0.758
Echinococcus granulosus cyclins 0.019 0.0228 0.0228
Schistosoma mansoni furin-1 (S08 family) 0.0848 0.1519 0.1519
Brugia malayi Dopamine receptor protein 1 0.0314 0.0472 0.1292
Schistosoma mansoni alpha-1 adrenergic receptor 0.0314 0.0472 0.0472
Entamoeba histolytica cyclin family protein 0.019 0.0228 0.1766
Echinococcus granulosus tubulin subunit beta 0.0249 0.0342 0.0342
Schistosoma mansoni amine GPCR 0.0314 0.0472 0.0472
Echinococcus multilocularis dro:myosuppressin receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis cyclins, putative 0.0408 0.0656 0.3944
Echinococcus multilocularis neuropeptide receptor 0.0472 0.0781 0.0781
Echinococcus granulosus G2:mitotic specific cyclin B3 0.019 0.0228 0.0228
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0314 0.0472 0.0472
Echinococcus multilocularis serotonin receptor 0.0314 0.0472 0.0472
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0083 0.0018 0.5
Schistosoma mansoni cyclins 0.019 0.0228 0.0228
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Leishmania major cyclin 0.0408 0.0656 1
Plasmodium falciparum tubulin beta chain 0.0249 0.0342 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Schistosoma mansoni biogenic amine receptor 0.0314 0.0472 0.0472
Echinococcus granulosus tissue type plasminogen activator 0.0209 0.0264 0.0264
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0132 0.0114 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Plasmodium vivax tubulin beta chain, putative 0.0249 0.0342 1
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0314 0.0472 0.1292
Echinococcus granulosus cyclins 0.019 0.0228 0.0228
Trypanosoma brucei beta tubulin 0.0249 0.0342 0.5082
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Echinococcus granulosus furin 0.1672 0.3138 0.3138
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0083 0.0018 1
Giardia lamblia Beta tubulin 0.0249 0.0342 0.3449
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Echinococcus multilocularis g protein coupled receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis aminopeptidase N 0.0118 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) melatonin receptor type 1A 0.0314 0.0472 0.1292
Echinococcus granulosus neuroendocrine convertase 2 0.1272 0.2352 0.2352
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0314 0.0472 0.0472
Echinococcus granulosus fmrfamide receptor 0.0314 0.0472 0.0472
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0083 0.0018 1
Loa Loa (eye worm) tubulin beta-4 chain 0.0249 0.0342 0.0938
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0507 0.085 0.085
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0314 0.0472 0.0472
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0314 0.0472 0.0472
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Brugia malayi sulfakinin receptor protein 0.0314 0.0472 0.1292
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Toxoplasma gondii PAN domain-containing protein 0.029 0.0423 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Giardia lamblia Beta tubulin 0.0249 0.0342 0.3449
Echinococcus granulosus G protein coupled receptor 139 0.0314 0.0472 0.0472
Brugia malayi neuropeptide F receptor 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Plasmodium vivax protein kinase Crk2 0.0144 0.0136 0.3659
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0314 0.0472 0.0472
Onchocerca volvulus 0.0314 0.0472 0.5447
Loa Loa (eye worm) hypothetical protein 0.0218 0.0282 0.0773
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0515 0.0866 0.0866
Echinococcus granulosus g protein coupled receptor 0.0314 0.0472 0.0472
Brugia malayi Dopamine receptor 0.0314 0.0472 0.1292
Brugia malayi putative neuropeptide receptor 0.0314 0.0472 0.1292
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0314 0.0472 0.1292
Loa Loa (eye worm) TK/EGFR protein kinase 0.0247 0.0339 0.093
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0264 0.3856
Entamoeba histolytica tubulin family protein 0.0249 0.0342 0.3959
Entamoeba histolytica tubulin family protein 0.0249 0.0342 0.3959
Echinococcus granulosus tachykinin peptides receptor 99D 0.0314 0.0472 0.0472
Toxoplasma gondii beta-tubulin, putative 0.0249 0.0342 0.8006
Echinococcus granulosus Tubulin beta 2C chain 0.0249 0.0342 0.0342
Onchocerca volvulus 0.0515 0.0866 1
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus granulosus cyclins 0.019 0.0228 0.0228
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0083 0.0018 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0314 0.0472 0.0472
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis tubulin epsilon chain, putative 0.0249 0.0342 0.2004
Echinococcus granulosus biogenic amine 5HT receptor 0.0314 0.0472 0.0472
Brugia malayi Protein kinase domain containing protein 0.0209 0.0264 0.0723
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0314 0.0472 0.1292
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0507 0.085 0.5143
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0136 0.0733
Schistosoma mansoni hypothetical protein 0.0314 0.0472 0.0472
Schistosoma mansoni tubulin subunit beta 0.0249 0.0342 0.0342
Echinococcus granulosus neuropeptide receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0507 0.085 0.5143
Trichomonas vaginalis cyclin B, putative 0.0408 0.0656 0.3944
Trypanosoma cruzi cyclin, putative 0.0408 0.0656 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0314 0.0472 0.1292
Loa Loa (eye worm) cyclin domain-containing protein 0.019 0.0228 0.0626
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0424 0.0687 0.4133
Schistosoma mansoni amine GPCR 0.0314 0.0472 0.0472
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Trypanosoma cruzi cdc2-related kinase 3 0.0144 0.0136 0.1859
Schistosoma mansoni hypothetical protein 0.0377 0.0594 0.0594
Schistosoma mansoni biogenic amine receptor 0.0314 0.0472 0.0472
Brugia malayi Melatonin receptor type 1A 0.0314 0.0472 0.1292
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis tubulin epsilon chain, putative 0.0249 0.0342 0.2004
Echinococcus granulosus Tubulin beta 2C chain 0.0249 0.0342 0.0342
Brugia malayi putative neuropeptide receptor NPR1 0.0314 0.0472 0.1292
Brugia malayi beta-tubulin, identical 0.0249 0.0342 0.0938
Schistosoma mansoni hypothetical protein 0.0132 0.0114 0.0114
Toxoplasma gondii kringle domain-containing protein 0.0209 0.0264 0.6075
Echinococcus multilocularis Tubulin beta 2C chain 0.0249 0.0342 0.0342
Echinococcus multilocularis cyclin B3 1 0.019 0.0228 0.0228
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0144 0.0136 0.1859
Echinococcus granulosus beta tubulin 0.0249 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Brugia malayi RE15519p 0.0314 0.0472 0.1292
Echinococcus multilocularis sex peptide receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) TK/ROR protein kinase 0.0209 0.0264 0.0723
Giardia lamblia Cyclin A 0.019 0.0228 0.1539
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni opsin-like receptor 0.0314 0.0472 0.0472
Schistosoma mansoni tyrosine kinase 0.0247 0.0339 0.0339
Trichomonas vaginalis tubulin alpha chain, putative 0.0249 0.0342 0.2004
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0136 0.0136
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0144 0.0136 0.0374
Mycobacterium leprae Possible secreted protease 0.0083 0.0018 0.5
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0314 0.0472 0.0472
Onchocerca volvulus 0.0118 0.0086 0.0988
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0144 0.0136 0.1859
Onchocerca volvulus 0.0314 0.0472 0.5447
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus multilocularis neuropeptides capa receptor 0.113 0.2073 0.2073
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus granulosus cyclins 0.019 0.0228 0.0228
Schistosoma mansoni opsin-like receptor 0.0314 0.0472 0.0472
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Brugia malayi G protein-coupled receptor 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Brugia malayi GnHR receptor homolog 0.0314 0.0472 0.1292
Trichomonas vaginalis cyclins, putative 0.019 0.0228 0.13
Trypanosoma cruzi cyclin 6, putative 0.0408 0.0656 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0314 0.0472 0.0472
Schistosoma mansoni tubulin subunit beta 0.0249 0.0342 0.0342
Schistosoma mansoni tubulin subunit beta 0.0249 0.0342 0.0342
Echinococcus multilocularis orexin receptor type 2 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis cyclin dependent kinase 0.0144 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Plasmodium falciparum cyclin 0.019 0.0228 0.6488
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0083 0.0018 0.0018
Echinococcus granulosus tubulin beta 4A class IVa 0.0249 0.0342 0.0342
Schistosoma mansoni cyclin B3 0.019 0.0228 0.0228
Schistosoma mansoni inhibitor of apoptosis protein 0.0132 0.0114 0.0114
Echinococcus granulosus neuropeptides capa receptor 0.113 0.2073 0.2073
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus multilocularis beta tubulin 0.0249 0.0342 0.0342
Brugia malayi hypothetical protein 0.0314 0.0472 0.1292
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus multilocularis somatostatin receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis fmrfamide receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis tubulin gamma chain, putative 0.0249 0.0342 0.2004
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0083 0.0018 0.0049
Echinococcus granulosus neuropeptide Y receptor 0.0314 0.0472 0.0472
Echinococcus granulosus neuropeptides capa receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Giardia lamblia High cysteine membrane protein Group 2 0.0448 0.0733 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis neuropeptide Y receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni neuropeptide receptor 0.0314 0.0472 0.0472
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Trypanosoma brucei cdc2-related kinase 1 0.0144 0.0136 0.1859
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Echinococcus granulosus biogenic amine 5HT receptor 0.0314 0.0472 0.0472
Schistosoma mansoni biogenic amine (5HT) receptor 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0132 0.0114 0.0311
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Echinococcus granulosus 7TM GPCR rhodopsin 0.0314 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Trypanosoma cruzi cdc2-related kinase 3 0.0144 0.0136 0.1859
Leishmania major beta tubulin 0.0249 0.0342 0.5082
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0132 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0142 0.0133 0.0365
Echinococcus granulosus neuropeptide Y receptor 0.0314 0.0472 0.0472
Schistosoma mansoni biogenic amine receptor 0.0314 0.0472 0.0472
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0314 0.0472 0.0472
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0507 0.085 0.5143
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0083 0.0018 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Brugia malayi neuropeptide F receptor 0.0314 0.0472 0.1292
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0314 0.0472 0.0472
Toxoplasma gondii beta-1 tubulin, putative 0.0249 0.0342 0.8006
Echinococcus granulosus neuropeptide s receptor 0.0314 0.0472 0.0472
Echinococcus granulosus Tubulin beta 2C chain 0.0249 0.0342 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Schistosoma mansoni hypothetical protein 0.0209 0.0264 0.0264
Echinococcus granulosus orexin receptor type 2 0.0314 0.0472 0.0472
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0083 0.0018 0.5
Echinococcus granulosus cyclin dependent kinase 5 0.0144 0.0136 0.0136
Echinococcus granulosus inhibitor of apoptosis protein 0.0132 0.0114 0.0114
Onchocerca volvulus 0.0083 0.0018 0.0205
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0314 0.0472 0.0472
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2362 0.4492 0.4492
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0515 0.0866 0.0866
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0408 0.0656 1
Brugia malayi AKH receptor 0.0314 0.0472 0.1292
Schistosoma mansoni amine GPCR 0.0314 0.0472 0.0472
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0507 0.085 0.5143
Onchocerca volvulus 0.0441 0.072 0.8316
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Brugia malayi G-protein coupled receptor 0.0314 0.0472 0.1292
Trichomonas vaginalis cyclins, putative 0.0408 0.0656 0.3944
Loa Loa (eye worm) hypothetical protein 0.1672 0.3138 0.8599
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0314 0.0472 0.0472
Echinococcus multilocularis tissue type plasminogen activator 0.0209 0.0264 0.0264
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0314 0.0472 0.0472
Echinococcus multilocularis cyclin dependent kinase 5 0.0144 0.0136 0.0136
Onchocerca volvulus Deterin homolog 0.0132 0.0114 0.1313
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0228 0.13
Echinococcus granulosus cyclin b3 0.019 0.0228 0.0228
Brugia malayi Cyclin, N-terminal domain containing protein 0.019 0.0228 0.0626
Schistosoma mansoni tubulin subunit beta 0.0249 0.0342 0.0342
Brugia malayi G protein-coupled receptor F59B2.13 0.0314 0.0472 0.1292
Echinococcus multilocularis cyclins 0.019 0.0228 0.0228
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0249 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Loa Loa (eye worm) hypothetical protein 0.0314 0.0472 0.1292
Echinococcus multilocularis cyclin dependent kinase 1 0.0144 0.0136 0.0136
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0314 0.0472 0.0472
Brugia malayi Cyclin, N-terminal domain containing protein 0.0408 0.0656 0.1798
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0083 0.0018 0.5
Schistosoma mansoni neuropeptide receptor 0.0314 0.0472 0.0472
Onchocerca volvulus 0.0314 0.0472 0.5447
Echinococcus multilocularis neuropeptide FF receptor 2 0.1932 0.3649 0.3649
Trypanosoma brucei beta tubulin 0.0249 0.0342 0.5082
Brugia malayi follicle stimulating hormone receptor 0.0314 0.0472 0.1292
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0083 0.0018 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0314 0.0472 0.1292
Trichomonas vaginalis conserved hypothetical protein 0.0377 0.0594 0.3561
Echinococcus multilocularis membrane bound transcription factor site 1 0.0083 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0083 0.0018 0.0049
Echinococcus granulosus Tubulin beta 2C chain 0.0249 0.0342 0.0342
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0136 0.0733
Echinococcus multilocularis neuropeptide Y receptor 0.0314 0.0472 0.0472
Echinococcus granulosus serotonin receptor 0.0314 0.0472 0.0472
Echinococcus granulosus rhodopsin orphan GPCR 0.0314 0.0472 0.0472
Echinococcus multilocularis Tubulin beta 2C chain 0.0249 0.0342 0.0342
Trichomonas vaginalis cyclin A, putative 0.0408 0.0656 0.3944
Trichomonas vaginalis cyclin B, putative 0.0408 0.0656 0.3944
Loa Loa (eye worm) neuropeptide F receptor 0.0314 0.0472 0.1292
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0314 0.0472 0.5447
Trichomonas vaginalis cyclins, putative 0.0408 0.0656 0.3944
Trypanosoma brucei cdc2-related kinase 3 0.0144 0.0136 0.1859
Echinococcus granulosus allatostatin A receptor 0.0314 0.0472 0.0472
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0209 0.0264 0.7588
Toxoplasma gondii subtilisin SUB12 0.0102 0.0054 0.0903

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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