Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.1054 | 0.1184 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.5431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.2052 | 0.3645 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | ICD-1 protein | 0.0034 | 0.5431 | 0.6698 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0114 | 0.0114 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.1054 | 0.1768 |
Echinococcus granulosus | transcription factor btf3 | 0.0034 | 0.5431 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0839 | 0.1364 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.1054 | 0.1768 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2052 | 0.3645 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.1054 | 0.1768 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.5431 | 0.5 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4619 | 0.8474 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.1054 | 0.1054 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0034 | 0.5431 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.5275 | 0.5275 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0114 | 0.0114 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.1054 | 0.1768 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0114 | 0.0114 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.1054 | 0.2229 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0114 | 0.0114 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.8052 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.5431 | 0.5 |
Schistosoma mansoni | transcription factor btf3 | 0.0034 | 0.5431 | 0.5431 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2052 | 0.2052 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2052 | 0.3645 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0215 | 0.0215 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0531 | 0.0784 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.1054 | 0.1768 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0114 | 0.0114 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0784 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0215 | 0.0127 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0531 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4331 | 0.5313 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.1054 | 0.1184 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0034 | 0.5431 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.1054 | 0.1054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.5431 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.8052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2052 | 0.2441 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.2052 | 0.2441 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.1054 | 0.1768 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.1054 | 0.1184 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.1054 | 0.2229 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2052 | 0.3645 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.1054 | 0.1768 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0215 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.8052 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.1054 | 0.1054 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.1054 | 0.1054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.5431 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2052 | 0.2052 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0215 | 0.0189 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0839 | 0.1364 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0114 | 0.0114 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4331 | 0.5313 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.1054 | 0.1768 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0215 | 0.0127 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.1054 | 0.2229 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.1054 | 0.1054 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.8052 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2052 | 0.2052 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.5431 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2052 | 0.3645 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0531 | 0.0784 |
Echinococcus multilocularis | transcription factor btf3 | 0.0034 | 0.5431 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.2052 | 0.2441 |
Onchocerca volvulus | 0.0028 | 0.4331 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.1054 | 0.1054 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.5275 | 0.6501 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0034 | 0.5431 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4619 | 0.4619 |
Brugia malayi | beta-NAC-like protein | 0.0034 | 0.5431 | 0.6698 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4619 | 0.4619 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0034 | 0.5431 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.2052 | 0.3645 |
Leishmania major | basic transcription factor 3a, putative | 0.0034 | 0.5431 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.1054 | 0.1768 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0784 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.8854 | 1 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0819 | 0.0888 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.1054 | 0.1054 |
Onchocerca volvulus | 0.001 | 0.1054 | 0.2229 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.5275 | 0.6501 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4331 | 0.4331 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0215 | 0.0127 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.2052 | 0.2441 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0839 | 0.0913 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.1054 | 0.1768 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.1054 | 0.1768 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0215 | 0.0215 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0114 | 0.0114 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.1054 | 0.1054 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0114 | 0.0114 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2052 | 0.2052 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.1054 | 0.1054 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4619 | 0.8474 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.1054 | 0.1184 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.