Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0117 | 0.0122 | 0.0057 |
Toxoplasma gondii | aminopeptidase N protein | 0.0117 | 0.0122 | 1 |
Brugia malayi | TATA binding protein associated factor | 0.0117 | 0.0122 | 0.0057 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0117 | 0.0122 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0066 | 0.0066 |
Entamoeba histolytica | aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Onchocerca volvulus | 0.0117 | 0.0122 | 0.5 | |
Trypanosoma cruzi | aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0096 | 0.0066 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0117 | 0.0122 | 0.0057 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0117 | 0.0122 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0117 | 0.0122 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0117 | 0.0122 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0004 | 0.0004 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0117 | 0.0122 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0004 | 0.0004 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.2209 | 0.5617 | 1 |
Onchocerca volvulus | 0.0117 | 0.0122 | 0.5 | |
Mycobacterium leprae | probable zinc metalloprotease | 0.0096 | 0.0066 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0117 | 0.0122 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0004 | 0.0004 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0122 | 0.0122 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0117 | 0.0122 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0117 | 0.0122 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Echinococcus multilocularis | aminopeptidase N | 0.0117 | 0.0122 | 0.0102 |
Brugia malayi | hypothetical protein | 0.0117 | 0.0122 | 0.0057 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.2209 | 0.5617 | 1 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0117 | 0.0122 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0117 | 0.0122 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0117 | 0.0122 | 0.0102 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0117 | 0.0122 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0117 | 0.0122 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Echinococcus granulosus | aminopeptidase N | 0.0117 | 0.0122 | 0.0102 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0117 | 0.0122 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0117 | 0.0122 | 0.0102 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0117 | 0.0122 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0117 | 0.0122 | 0.5 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0117 | 0.0122 | 0.0122 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0122 | 0.0122 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0117 | 0.0122 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0117 | 0.0122 | 1 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.3878 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.1016 | 0.2482 | 0.2432 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.2209 | 0.5617 | 0.5617 |
Brugia malayi | Peptidase family M1 containing protein | 0.0117 | 0.0122 | 0.0057 |
Trypanosoma brucei | aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Onchocerca volvulus | 0.0117 | 0.0122 | 0.5 | |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0117 | 0.0122 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0117 | 0.0122 | 0.5 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0117 | 0.0122 | 0.0102 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.2209 | 0.5617 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0066 | 0.0066 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0117 | 0.0122 | 0.0102 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0117 | 0.0122 | 0.0122 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0117 | 0.0122 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | aminopeptidase N | 0.0117 | 0.0122 | 0.0122 |
Brugia malayi | Peptidase family M1 containing protein | 0.0117 | 0.0122 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0122 | 0.0122 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0117 | 0.0122 | 0.0102 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0117 | 0.0122 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0117 | 0.0122 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0122 | 0.0102 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.