Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.011 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0105 | 0.0023 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0235 | 0.0133 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Brugia malayi | TATA binding protein associated factor | 0.0235 | 0.0133 | 0.011 |
Toxoplasma gondii | aminopeptidase N protein | 0.0235 | 0.0133 | 1 |
Brugia malayi | hypothetical protein | 0.0235 | 0.0133 | 0.011 |
Onchocerca volvulus | 0.0235 | 0.0133 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0023 | 0.0023 |
Entamoeba histolytica | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0235 | 0.0133 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0105 | 0.0023 | 0.5 |
Onchocerca volvulus | 0.0235 | 0.0133 | 0.5 | |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0023 | 0.0023 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.4421 | 0.3657 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0235 | 0.0133 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0235 | 0.0133 | 1 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0235 | 0.0133 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0235 | 0.0133 | 0.5 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus granulosus | aminopeptidase N | 0.0235 | 0.0133 | 0.0301 |
Brugia malayi | hypothetical protein | 0.0235 | 0.0133 | 0.011 |
Echinococcus multilocularis | aminopeptidase N | 0.0235 | 0.0133 | 0.0301 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0235 | 0.0133 | 0.5 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.4421 | 0.3657 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.0133 | 0.0133 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0235 | 0.0133 | 1 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0235 | 0.0133 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0235 | 0.0133 | 0.0133 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0235 | 0.0133 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0235 | 0.0133 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.011 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.4421 | 0.3657 | 0.3657 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 1.1954 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.2033 | 0.1646 | 0.1627 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.0133 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0235 | 0.0133 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0235 | 0.0133 | 0.5 |
Onchocerca volvulus | 0.0235 | 0.0133 | 0.5 | |
Trypanosoma brucei | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.4421 | 0.3657 | 1 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0023 | 0.0023 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.0133 | 0.0133 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0235 | 0.0133 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.011 |
Loa Loa (eye worm) | aminopeptidase N | 0.0235 | 0.0133 | 0.0133 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.