Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0235 | 0.0133 | 0.0301 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0235 | 0.0133 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0235 | 0.0133 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.4421 | 0.3657 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0235 | 0.0133 | 0.5 |
Onchocerca volvulus | 0.0235 | 0.0133 | 0.5 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Brugia malayi | Peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0235 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.4421 | 0.3657 | 0.3657 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0235 | 0.0133 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0105 | 0.0023 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.011 |
Echinococcus granulosus | aminopeptidase N | 0.0235 | 0.0133 | 0.0301 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Onchocerca volvulus | 0.0235 | 0.0133 | 0.5 | |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0235 | 0.0133 | 0.5 |
Brugia malayi | hypothetical protein | 0.2033 | 0.1646 | 0.1627 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0105 | 0.0023 | 0.5 |
Trypanosoma brucei | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0235 | 0.0133 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0235 | 0.0133 | 1 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.4421 | 0.3657 | 1 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0235 | 0.0133 | 0.0301 |
Entamoeba histolytica | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Onchocerca volvulus | 0.0235 | 0.0133 | 0.5 | |
Brugia malayi | Peptidase family M1 containing protein | 0.0235 | 0.0133 | 0.011 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0235 | 0.0133 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Brugia malayi | hypothetical protein | 0.0235 | 0.0133 | 0.011 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.0133 | 0.0133 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0235 | 0.0133 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | aminopeptidase N | 0.0235 | 0.0133 | 0.0133 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0235 | 0.0133 | 0.5 |
Toxoplasma gondii | aminopeptidase N protein | 0.0235 | 0.0133 | 1 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 1.1954 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.0133 | 0.0133 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0235 | 0.0133 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.4421 | 0.3657 | 1 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.0133 | 0.0133 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Brugia malayi | hypothetical protein | 0.0235 | 0.0133 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0002 | 0.0002 |
Brugia malayi | TATA binding protein associated factor | 0.0235 | 0.0133 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0023 | 0.0023 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0235 | 0.0133 | 0.5 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0235 | 0.0133 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0023 | 0.0023 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0235 | 0.0133 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0235 | 0.0133 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0235 | 0.0133 | 0.0301 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.