Detailed information for compound 846101

Basic information

Technical information
  • TDR Targets ID: 846101
  • Name: (4-ethoxyphenyl)-(6-methoxy-4-phenylsulfonylq uinolin-3-yl)methanone
  • MW: 447.503 | Formula: C25H21NO5S
  • H donors: 0 H acceptors: 4 LogP: 4.64 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)C(=O)c1cnc2c(c1S(=O)(=O)c1ccccc1)cc(cc2)OC
  • InChi: 1S/C25H21NO5S/c1-3-31-18-11-9-17(10-12-18)24(27)22-16-26-23-14-13-19(30-2)15-21(23)25(22)32(28,29)20-7-5-4-6-8-20/h4-16H,3H2,1-2H3
  • InChiKey: DZTSZWLWRUZQEH-UHFFFAOYSA-N  

Network

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Synonyms

  • (4-ethoxyphenyl)-(6-methoxy-4-phenylsulfonyl-3-quinolyl)methanone
  • (4-ethoxyphenyl)-(6-methoxy-4-phenylsulfonyl-quinolin-3-yl)methanone
  • ZINC02713698

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma brucei trypanothione reductase 0.0098 0.0428 0.8999
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0059 0.0447
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0015 0.0011 0.0011
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0058 0.007
Loa Loa (eye worm) hypothetical protein 0.0065 0.0263 0.097
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0395 0.0552
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0015 0.0011 0.023
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0157 0.0661
Echinococcus granulosus muscleblind protein 0.0298 0.1435 0.204
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0139 0.0179
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0067 0.0274 0.0392
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0024
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0107 0.2245
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.005 0.005
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0141 0.2971
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0139 0.2921
Trichomonas vaginalis C-MYB, putative 0.0039 0.0132 0.1035
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0067 0.0274 0.5766
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0379 0.1844 0.2625
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0141 0.1107
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0067 0.0274 0.5766
Brugia malayi mbt repeat family protein 0.0094 0.041 0.1726
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0028 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0078 0.1634
Echinococcus granulosus tar DNA binding protein 0.0064 0.0259 0.0358
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0157 0.0212
Echinococcus granulosus chromobox protein 1 0.0067 0.0275 0.0381
Trichomonas vaginalis heat shock protein, putative 0.0073 0.0303 0.2405
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Loa Loa (eye worm) hepatopoietin HPO2 0.0033 0.0103 0.038
Onchocerca volvulus 0.0059 0.0235 0.2066
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0037 0.0266
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0024
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.004 0.0149
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0067 0.0274 0.5766
Leishmania major mitochondrial DNA topoisomerase II 0.0015 0.0011 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0539
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0274 0.5766
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0015 0.0011 0.0056
Schistosoma mansoni kinase 0.0046 0.017 0.0243
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.019 0.08
Entamoeba histolytica hypothetical protein 0.0036 0.012 0.2821
Entamoeba histolytica hypothetical protein 0.0031 0.009 0.2066
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0067 0.0274 0.1155
Schistosoma mansoni hypothetical protein 0.0065 0.0263 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0157 0.0661
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0088 0.0126
Schistosoma mansoni nuclear hormone receptor 0.0021 0.004 0.0058
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0053 0.0063
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.011 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0206 0.4821
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0052 0.1097
Entamoeba histolytica hypothetical protein 0.0036 0.012 0.2821
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0095 0.0416 0.0594
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0107 0.0096
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0141 0.0141
Schistosoma mansoni heat shock protein 0.0073 0.0303 0.0432
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0098 0.0428 0.0584
Echinococcus granulosus lamin 0.0031 0.0094 0.0121
Schistosoma mansoni Smad4 0.0018 0.0028 0.004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Giardia lamblia Pms1-like protein 0.0015 0.0011 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0015 0.0011 0.023
Brugia malayi kinase, mitochondrial precursor 0.0015 0.0011 0.0046
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Toxoplasma gondii thioredoxin reductase 0.0098 0.0428 0.1544
Leishmania major hypothetical protein, conserved 0.0015 0.0011 0.0114
Loa Loa (eye worm) DR-78 0.0021 0.004 0.0149
Loa Loa (eye worm) hypothetical protein 0.0552 0.2714 1
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.0011 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0157 0.0661
Schistosoma mansoni DNA polymerase eta 0.0068 0.0277 0.0395
Loa Loa (eye worm) hypothetical protein 0.005 0.019 0.0701
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.005 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0157 0.0578
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0132 0.1035
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.5766
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0552 0.2714 0.3869
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0963 0.0963
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0563 0.2773 0.2766
Schistosoma mansoni nuclear receptor 0.0021 0.004 0.0058
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0091 0.0396 0.4112
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0086 0.0696
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Brugia malayi hypothetical protein 0.0018 0.0028 0.012
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0094 0.0345
Brugia malayi glutathione reductase 0.0098 0.0428 0.1803
Plasmodium falciparum thioredoxin reductase 0.0098 0.0428 1
Plasmodium vivax phosphodiesterase gamma, putative 0.0067 0.0274 0.6407
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0107 0.0394
Plasmodium vivax aspartyl protease, putative 0.0018 0.0028 0.0664
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.005 0.0181
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.004
Entamoeba histolytica serine/threonine protein kinase, putative 0.0091 0.0396 1
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0132 0.1035
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0059 0.0447
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0157 0.0212
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0015 0.0011 0.023
Brugia malayi CHD4 protein 0.0014 0.0009 0.0037
Echinococcus multilocularis thioredoxin glutathione reductase 0.0098 0.0428 0.06
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.005 0.117
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.1245 1
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.004 0.0058
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0107 0.0385
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0077 0.0324 0.0451
Trichomonas vaginalis C-MYB, putative 0.0039 0.0132 0.1035
Loa Loa (eye worm) RNA binding protein 0.0064 0.0259 0.0954
Schistosoma mansoni lamin 0.0031 0.0094 0.0134
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Giardia lamblia Grp94/Hsp90 0.0058 0.0228 0.084
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0067 0.0274 0.6407
Plasmodium falciparum LCCL domain-containing protein 0.0065 0.0263 0.6146
Echinococcus multilocularis dna polymerase eta 0.0068 0.0277 0.0383
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Echinococcus granulosus RUN 0.0065 0.0263 0.0364
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0077 0.0326 0.1201
Toxoplasma gondii heat shock protein HSP90 0.0073 0.0303 0.1091
Leishmania major hypothetical protein, conserved 0.0067 0.0274 0.285
Echinococcus granulosus voltage dependent calcium channel 0.0022 0.0047 0.0054
Brugia malayi hypothetical protein 0.0036 0.012 0.0503
Echinococcus granulosus bloom syndrome protein 0.002 0.0037 0.004
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0037 0.0137
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0037 0.0266
Toxoplasma gondii aspartyl protease ASP1 0.0077 0.0326 0.1175
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.2015 0.2869
Plasmodium falciparum glutathione reductase 0.0098 0.0428 1
Giardia lamblia Hypothetical protein 0.0067 0.0274 0.1011
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0274 0.5766
Toxoplasma gondii Hsp90 domain-containing protein 0.003 0.0086 0.0312
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0028 0.0103
Schistosoma mansoni polycystin 1-related 0.0065 0.0263 0.0376
Leishmania major DNA topoisomerase ii 0.0015 0.0011 0.0114
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0052 0.0388
Toxoplasma gondii aldehyde dehydrogenase 0.0204 0.0963 0.3472
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0037 0.004
Echinococcus granulosus intermediate filament protein 0.0031 0.0094 0.0121
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0067 0.0274 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.004 0.0058
Echinococcus granulosus Smad4 0.0018 0.0028 0.0027
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0062 0.0259
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.0428 0.8999
Treponema pallidum heat shock protein 90 0.0058 0.0228 0.0217
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0157 0.0212
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0091 0.0396 0.0554
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0017 0.0011
Brugia malayi Pre-SET motif family protein 0.0202 0.0955 0.4022
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0292
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.1245 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.004 0.0045
Schistosoma mansoni lipoxygenase 0.0204 0.0963 0.1375
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0052 0.0388
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0107 0.0107
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0086 0.196
Plasmodium vivax aspartyl protease, putative 0.0018 0.0028 0.0664
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.0064 0.0257 0.0949
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0395 0.0564
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0552 0.2714 0.3876
Loa Loa (eye worm) hypothetical protein 0.0031 0.0094 0.0345
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0107 0.2494
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0322 0.6757
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0037 0.0156
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0028 0.004
Onchocerca volvulus 0.0094 0.041 0.3682
Echinococcus multilocularis Smad4 0.0018 0.0028 0.0027
Mycobacterium tuberculosis Probable oxidoreductase 0.0248 0.1184 0.164
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0563 0.2773 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0507 0.183
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0086 0.0111
Giardia lamblia Heat shock protein HSP 90-alpha 0.0058 0.0228 0.084
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0042 0.0872
Trypanosoma cruzi DNA topoisomerase II, putative 0.0015 0.0011 0.023
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0015 0.0011 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0088 0.0113
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0086 0.1815
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0107 0.1109
Echinococcus granulosus L aminoadipate semialdehyde 0.008 0.0341 0.0475
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0042 0.0872
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0141 0.019
Echinococcus multilocularis RUN 0.0065 0.0263 0.0364
Leishmania major importin beta-1 subunit, putative 0.0023 0.0052 0.0542
Trypanosoma brucei heat shock protein 90, putative 0.0073 0.0303 0.6356
Schistosoma mansoni intermediate filament proteins 0.0031 0.0094 0.0134
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Schistosoma mansoni chromobox protein 0.0067 0.0275 0.0393
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.005 0.117
Onchocerca volvulus 0.0018 0.0028 0.0162
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0552 0.2714 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0157 0.0661
Schistosoma mansoni ran 0.0021 0.0042 0.0059
Plasmodium falciparum importin beta, putative 0.0028 0.0079 0.185
Echinococcus multilocularis cpg binding protein 0.0063 0.0252 0.0348
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.012 0.0171
Schistosoma mansoni cathepsin D (A01 family) 0.0077 0.0326 0.0466
Leishmania major ferric reductase, putative 0.0107 0.0476 0.4943
Plasmodium vivax thioredoxin reductase, putative 0.0098 0.0428 1
Echinococcus granulosus geminin 0.0686 0.3391 0.4837
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0058 0.0228 0.0303
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0141 0.019
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Leishmania major trypanothione reductase 0.0098 0.0428 0.4448
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Loa Loa (eye worm) hypothetical protein 0.0038 0.0126 0.0466
Brugia malayi chromobox protein homolog 3 0.0038 0.0126 0.0532
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Echinococcus granulosus dnaJ subfamily B 0.0413 0.2015 0.2869
Echinococcus granulosus lipoxygenase domain containing protein 0.0065 0.0263 0.0364
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.0011 0.0039
Schistosoma mansoni lamin 0.0031 0.0094 0.0134
Loa Loa (eye worm) X11 protein 0.0066 0.0271 0.0997
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Echinococcus multilocularis chromobox protein 1 0.0067 0.0275 0.0381
Echinococcus multilocularis muscleblind protein 1 0.0298 0.1435 0.204
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Onchocerca volvulus 0.023 0.1095 1
Plasmodium falciparum plasmepsin VIII, putative 0.0018 0.0028 0.0664
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.6407
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0274 0.2179
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0103 0.2169
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.041 0.3682
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Toxoplasma gondii hypothetical protein 0.0017 0.0022 0.0081
Echinococcus granulosus smad 0.0018 0.0028 0.0027
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Loa Loa (eye worm) hypothetical protein 0.0077 0.0326 0.1201
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1435 0.7163 1
Plasmodium falciparum plasmepsin I 0.0077 0.0326 0.7609
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0575 0.0821
Entamoeba histolytica heat shock protein 90, putative 0.0073 0.0303 0.7574
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0037 0.0865
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0204 0.0963 0.1331
Trypanosoma cruzi DNA topoisomerase II, putative 0.0015 0.0011 0.023
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0015 0.0011 0.0011
Onchocerca volvulus 0.0031 0.0094 0.0764
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0091 0.0396 0.0554
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0035
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Brugia malayi MH2 domain containing protein 0.0018 0.0028 0.0118
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.1109
Schistosoma mansoni rab6-interacting 0.0065 0.0263 0.0376
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0015 0.0011 0.0056
Schistosoma mansoni coup transcription factor 0.0044 0.0157 0.0224
Loa Loa (eye worm) TOPoisomerase family member 0.0015 0.0011 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0157 0.0578
Schistosoma mansoni apoptosis regulator bax 0.008 0.0339 0.0485
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.3882 0.5539
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0107 0.2245
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Mycobacterium ulcerans heat shock protein 90 0.0058 0.0228 0.0228
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0161 0.1265
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0067 0.0274 0.5766
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0141 0.0182
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0067 0.0274 0.5766
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0088 0.0318
Echinococcus granulosus heat shock protein 0.0073 0.0303 0.042
Mycobacterium tuberculosis Probable reductase 0.0223 0.1059 0.1465
Echinococcus granulosus heat shock protein 90 0.0058 0.0228 0.0313
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0095 0.0416 0.0583
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Schistosoma mansoni hypothetical protein 0.008 0.0339 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0126 0.0986
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0037 0.004
Loa Loa (eye worm) heat shock protein 90 0.0073 0.0303 0.1115
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Schistosoma mansoni hypothetical protein 0.008 0.0339 0.0485
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0079 0.1665
Brugia malayi Fli-1 protein 0.0216 0.1026 0.4318
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Echinococcus multilocularis amyloid beta A4 protein 0.0066 0.0271 0.0374
Onchocerca volvulus 0.0018 0.0028 0.0162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0396 0.0566
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0107 0.0134
Trypanosoma cruzi heat shock protein 90, putative 0.0058 0.0228 0.4789
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0067 0.0274 0.5766
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0223 0.1059 0.1465
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0274 0.5766
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0141 0.1102
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0206 0.4338
Schistosoma mansoni lipoxygenase 0.0321 0.1551 0.2215
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0077 0.0326 0.0453
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0963 0.0963
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0059 0.0447
Trypanosoma cruzi heat shock protein 90, putative 0.0043 0.0152 0.3204
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0153
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0015 0.0011 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0033 0.0138
Brugia malayi Pepsin A precursor 0.0018 0.0028 0.012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0395 0.1662
Trypanosoma cruzi heat shock protein 85, putative 0.0073 0.0303 0.6356
Leishmania major DNA polymerase eta, putative 0.004 0.0135 0.1405
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0107 0.0096
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0053 0.0223
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0044 0.0157 0.0212
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0067 0.0274 0.038
Plasmodium vivax SET domain protein, putative 0.003 0.0088 0.2057
Schistosoma mansoni ran 0.0021 0.0042 0.0059
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0141 0.2971
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.004 0.0045
Schistosoma mansoni cpg binding protein 0.0063 0.0252 0.036
Brugia malayi nuclear receptor RXR 0.0023 0.0053 0.0223
Loa Loa (eye worm) hypothetical protein 0.0095 0.0416 0.1534
Plasmodium vivax aspartyl proteinase, putative 0.0018 0.0028 0.0664
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0157 0.0578
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0223 0.1059 0.1465
Schistosoma mansoni smad1 5 8 and 0.0018 0.0028 0.004
Plasmodium vivax heat shock protein 86, putative 0.0073 0.0303 0.7063
Loa Loa (eye worm) transcription factor SMAD2 0.0267 0.1281 0.4721
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0011 0.0255
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0841 0.6746
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0157 0.0224
Brugia malayi nuclear receptor NHR-88 0.0021 0.004 0.017
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.004 0.0045
Echinococcus multilocularis musashi 0.0031 0.0094 0.0121
Loa Loa (eye worm) RecQ helicase 0.002 0.0037 0.0137
Echinococcus granulosus importin subunit beta 1 0.0028 0.0079 0.0101
Toxoplasma gondii ImpB/MucB/SamB family protein 0.004 0.0135 0.0488
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0039 0.0132 0.3156
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0067 0.0274 0.5766
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0017 0.007
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Plasmodium falciparum heat shock protein 90, putative 0.003 0.0086 0.2017
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0053 0.0223
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0015 0.0011 0.0011
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0563 0.2773 0.2773
Leishmania major cAMP-specific phosphodiesterase, putative 0.0067 0.0274 0.285
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0139 0.0128
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0395 0.1455
Leishmania major GTP-binding protein, putative 0.0021 0.0042 0.0431
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0016 0.001
Leishmania major hypothetical protein, conserved 0.0067 0.0274 0.285
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0015 0.0011 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0157 0.0212
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0395 0.0552
Echinococcus multilocularis heat shock protein 90 0.0058 0.0228 0.0313
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0139 0.1088
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0107 0.0828
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0107 0.2494
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0223 0.1059 0.1465
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0107 0.1109
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0157 0.0661
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0021 0.0076
Trypanosoma cruzi Heat shock protein 83, putative 0.0073 0.0303 0.6356
Plasmodium falciparum endoplasmin, putative 0.0045 0.0161 0.3758
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.004 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0037 0.0137
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.008 0.0339 0.0485
Brugia malayi SET domain containing protein 0.0013 0.0004 0.0016
Schistosoma mansoni cpg binding protein 0.0059 0.0235 0.0336
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0322 0.334
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trichomonas vaginalis sensor histidine kinase, putative 0.0015 0.0011 0.0056
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Echinococcus granulosus sodium channel protein 0.004 0.0138 0.0185
Trypanosoma brucei hypothetical protein, conserved 0.0067 0.0274 0.5766
Mycobacterium ulcerans DNA gyrase subunit B 0.0015 0.0011 0.0011
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.026 0.1245 0.4588
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.008 0.0339 0.0473
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Trypanosoma brucei DNA topoisomerase ii 0.0015 0.0011 0.023
Plasmodium vivax glutathione reductase, putative 0.0098 0.0428 1
Schistosoma mansoni nuclear receptor 0.0021 0.004 0.0058
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0086 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Trichomonas vaginalis receptor histidine kinase, putative 0.0015 0.0011 0.0056
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0077 0.0326 0.0466
Trypanosoma cruzi DNA polymerase eta, putative 0.0068 0.0277 0.5814
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0259 0.037
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0067 0.0274 0.2179
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Loa Loa (eye worm) heat shock protein 75 0.003 0.0086 0.0318
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0539
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0275 0.1015
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0067 0.0274 0.1011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0157 0.0661
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.005 0.0521
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0563 0.2773 0.3863
Echinococcus multilocularis smad 0.0018 0.0028 0.0027
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0275 0.2186
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1998 1 1
Trypanosoma brucei unspecified product 0.0041 0.0141 0.2971
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0248 0.1184 0.164
Brugia malayi intermediate filament protein 0.0031 0.0094 0.0395
Trypanosoma cruzi heat shock protein 85, putative 0.0073 0.0303 0.6356
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0141 0.1102
Brugia malayi MH1 domain containing protein 0.0018 0.0028 0.0118
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0095 0.0416 0.1752
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0034 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0157 0.0578
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0171
Schistosoma mansoni hypothetical protein 0.0303 0.1462 0.2088
Trichomonas vaginalis MYB3r3, putative 0.0039 0.0132 0.1035
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.1245 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.008 0.0341 0.0487
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.1245 1
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0159 0.0215
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0841 0.6746
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0079 0.0286
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0552 0.2714 0.3869
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.041 0.0574
Onchocerca volvulus 0.0065 0.0263 0.2327
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0195
Echinococcus multilocularis sodium channel protein 0.0077 0.0324 0.0451
Entamoeba histolytica hypothetical protein 0.0023 0.0052 0.1072
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0037 0.0385
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.1245 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0067 0.0274 0.5766
Trichomonas vaginalis pc-MYB2, putative 0.0039 0.0132 0.1035
Onchocerca volvulus Serine\/threonine kinase homolog 0.0091 0.0396 0.355
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Echinococcus multilocularis bloom syndrome protein 0.002 0.0037 0.004
Brugia malayi Thioredoxin reductase 0.0098 0.0428 0.1803
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0963 0.0963
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.2245
Schistosoma mansoni smad 0.0018 0.0028 0.004
Trypanosoma cruzi heat shock protein 90, putative 0.0073 0.0303 0.6356
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0157 0.0661
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0095 0.0416 0.0594
Giardia lamblia Heat shock protein HSP 90-alpha 0.0073 0.0303 0.1115
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0126 0.0986
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0204 0.0963 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0067 0.0274 0.1155
Brugia malayi TAR-binding protein 0.0064 0.0259 0.109
Schistosoma mansoni ap endonuclease 0.004 0.0139 0.0199
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0105
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0053 0.0195
Echinococcus multilocularis voltage dependent calcium channel 0.0095 0.0416 0.0583
Brugia malayi RNA, U transporter 1 0.0081 0.0343 0.1442
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0067 0.0274 0.1155
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.0396 0.8318
Schistosoma mansoni cpg binding protein 0.0063 0.0252 0.036
Echinococcus multilocularis GPCR, family 2 0.0016 0.0017 0.0011
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0141 0.0141
Schistosoma mansoni microtubule-associated protein tau 0.1403 0.7001 1
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.6407
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Echinococcus multilocularis histone acetyltransferase MYST2 0.0107 0.0476 0.0668
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0067 0.0274 0.038
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0028 0.0194
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0037 0.004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1998 1 1
Trypanosoma brucei heat shock protein 90, putative 0.0073 0.0303 0.6356
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0195
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0037 0.0865
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0195
Loa Loa (eye worm) hypothetical protein 0.003 0.0088 0.0325
Echinococcus granulosus cpg binding protein 0.0063 0.0252 0.0348
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0095 0.0416 0.0583
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0103 0.2411
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0015 0.0011 0.0003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0157 0.0212
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0157 0.0212
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.004 0.017
Echinococcus multilocularis Polycystic kidney disease protein 0.0065 0.0263 0.0364
Plasmodium vivax aspartyl proteinase, putative 0.0077 0.0326 0.7609
Schistosoma mansoni aldehyde dehydrogenase 0.0204 0.0963 0.1375
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0079 0.0101
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0021 0.0087
Loa Loa (eye worm) voltage-dependent calcium channel 0.0022 0.0047 0.0171
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0058 0.0228 0.0217
Schistosoma mansoni memapsin-2 (A01 family) 0.0018 0.0028 0.0041
Treponema pallidum NADH oxidase 0.0034 0.0107 0.0096
Giardia lamblia Myb 1-like protein 0.0039 0.0133 0.0491
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0015 0.0011 0.0011
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0107 0.0153
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0017 0.0011
Leishmania major hypothetical protein, conserved 0.0033 0.0103 0.1072
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0157 0.0578
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0139 0.1444
Onchocerca volvulus 0.0031 0.0094 0.0764
Brugia malayi ImpB/MucB/SamB family protein 0.0068 0.0277 0.1165
Loa Loa (eye worm) hypothetical protein 0.003 0.0085 0.0314
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0017 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0259 0.037
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0024
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Brugia malayi mbt repeat family protein 0.0094 0.041 0.1726
Echinococcus multilocularis snurportin 1 0.0303 0.1462 0.2078
Schistosoma mansoni nuclear hormone receptor 0.0021 0.004 0.0058
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0067 0.0274 0.1155
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0076 0.0096
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0107 0.0107
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Plasmodium vivax aspartyl protease, putative 0.0018 0.0028 0.0664
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0067 0.0274 0.038
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0067 0.0274 0.038
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0157 0.0212
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0223 0.1059 0.1465
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.004 0.0272
Echinococcus multilocularis L aminoadipate semialdehyde 0.008 0.0341 0.0475
Brugia malayi hypothetical protein 0.0023 0.0053 0.0223
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0484 0.2376 0.3385
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0141 0.0182
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0028 0.0027
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0015 0.0011 0.0003
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0139 0.2921
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0132 0.1035
Trichomonas vaginalis receptor histidine kinase, putative 0.0015 0.0011 0.0056
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0077 0.0326 0.2594
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0103 0.2411
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0103 0.0372
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0157 0.0224
Brugia malayi MH2 domain containing protein 0.0267 0.1281 0.5393
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0088 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Trichomonas vaginalis endoplasmin, putative 0.0045 0.0161 0.1265
Toxoplasma gondii heat shock protein 90, putative 0.0073 0.0303 0.1091
Brugia malayi Nuclear hormone receptor E75 0.0021 0.004 0.017
Brugia malayi hypothetical protein 0.0021 0.004 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0058 0.0228 0.0313
Loa Loa (eye worm) doublecortin family protein 0.0065 0.0263 0.097
Brugia malayi ecdysteroid receptor 0.0044 0.0157 0.0661
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0035
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0206 0.4338
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0141 0.1198
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0012 0.0005
Echinococcus granulosus snurportin 1 0.0303 0.1462 0.2078
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0139 0.0186
Loa Loa (eye worm) calcium channel 0.0095 0.0416 0.1534
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0095 0.0416 0.0583
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.008 0.0339 0.1428
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0059 0.0447
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0259 0.0954
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0126 0.1065
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0039 0.0133 0.0481
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0015 0.0011 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Plasmodium falciparum phosphodiesterase delta, putative 0.0067 0.0274 0.6407
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0107 0.0828
Plasmodium falciparum plasmepsin IV 0.0077 0.0326 0.7609
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0206 0.4338
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0083
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0141 0.0202
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0018 0.0028 0.0103
Brugia malayi hypothetical protein 0.0035 0.0111 0.0466
Trichomonas vaginalis MYB, putative 0.0039 0.0133 0.1042
Brugia malayi hypothetical protein 0.0065 0.0263 0.1108
Leishmania major DNA polymerase kappa, putative 0.0041 0.0141 0.1469
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.012 0.0158
Loa Loa (eye worm) hypothetical protein 0.0067 0.0274 0.1011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0157 0.0661
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0157 0.0578
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.012 0.0158
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0015 0.0011 0.0056
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Leishmania major calcium channel protein, putative,ion transporter, putative 0.004 0.0138 0.1432
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Plasmodium vivax endoplasmin, putative 0.0073 0.0303 0.7063
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0077 0.0326 0.0453
Treponema pallidum hypothetical protein 0.0031 0.009 0.008
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0015 0.0011 0.0255
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0033 0.0103 0.0135
Plasmodium falciparum heat shock protein 90 0.0073 0.0303 0.7063
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.1109
Onchocerca volvulus 0.0021 0.004 0.0272
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0086 0.0111
Echinococcus granulosus endoplasmin 0.0058 0.0228 0.0313
Echinococcus multilocularis chromobox protein 1 0.0067 0.0275 0.0381
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0017 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0267 0.1281 0.4721
Trichomonas vaginalis heat shock protein, putative 0.0058 0.0228 0.1804
Onchocerca volvulus 0.008 0.0341 0.3043
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0062 0.0259
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0088 0.0126
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Echinococcus multilocularis endoplasmin 0.0058 0.0228 0.0313
Brugia malayi Probable DNA topoisomerase II 0.0015 0.0011 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0144 0.0205
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Loa Loa (eye worm) blistered cuticle protein 3 0.0228 0.1086 0.4002
Brugia malayi hypothetical protein 0.0021 0.004 0.017
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0037 0.0137
Schistosoma mansoni rab6-interacting 0.0065 0.0263 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.6407
Plasmodium vivax multidomain scavenger receptor, putative 0.0065 0.0263 0.6146
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0067 0.0274 0.6407
Schistosoma mansoni loxhd1 0.0065 0.0263 0.0376
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0061
Toxoplasma gondii aspartyl protease ASP3 0.0018 0.0028 0.0103
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.2245
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0094 0.0395
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.005 0.1053
Toxoplasma gondii aspartyl protease 0.0018 0.0028 0.0103
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0204 0.0963 0.1365
Trypanosoma brucei DNA polymerase eta, putative 0.0068 0.0277 0.5814
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0067 0.0274 0.2179
Brugia malayi hypothetical protein 0.0065 0.0263 0.1108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0107 0.2245
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Echinococcus multilocularis heat shock protein 90 0.0073 0.0303 0.042
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0067 0.0274 0.1155
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0274 0.5766
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0484 0.2376 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.0396 0.8318
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Onchocerca volvulus 0.0065 0.0263 0.2327
Echinococcus granulosus FTZ F1 alpha 0.0044 0.0157 0.0212
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0248 0.1184 0.164
Schistosoma mansoni pyruvate dehydrogenase 0.0015 0.0011 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0157 0.0212
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Onchocerca volvulus 0.0021 0.004 0.0272
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0274 0.5766
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0157 0.0224
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0259 0.109
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0015 0.0011 0.0011
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0067 0.0274 0.038
Brugia malayi serine/threonine-protein kinase plk-2 0.0091 0.0396 0.1667
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0067 0.0274 0.1155
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0322 0.6757
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0133 0.1042
Echinococcus granulosus microtubule associated protein 2 0.1403 0.7001 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0139 0.0512
Loa Loa (eye worm) endoplasmin 0.0073 0.0303 0.1115
Schistosoma mansoni endoplasmin 0.0073 0.0303 0.0432
Brugia malayi heat shock protein 90 0.0073 0.0303 0.1273
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0058 0.0228 0.2367
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.041 0.0574
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.2245
Echinococcus granulosus Polycystic kidney disease protein 0.0065 0.0263 0.0364
Echinococcus multilocularis lamin 0.0031 0.0094 0.0121
Plasmodium falciparum plasmepsin V 0.0018 0.0028 0.0664
Onchocerca volvulus 0.003 0.0085 0.0686
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0059 0.0447
Loa Loa (eye worm) hypothetical protein 0.0298 0.1435 0.5289
Entamoeba histolytica hypothetical protein 0.0036 0.012 0.2821
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0028 0.0027
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0235 0.0866
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.0795 0.7231
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0015 0.0011 0.0056
Echinococcus granulosus heat shock protein 90 0.0073 0.0303 0.042
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0321 0.1551 0.2206
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1998 1 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0139 0.0512
Schistosoma mansoni DNA helicase recq1 0.002 0.0037 0.0053
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0067 0.0274 0.038
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0016 0.001
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0141 0.019
Schistosoma mansoni hypothetical protein 0.0036 0.012 0.0171
Schistosoma mansoni amyloid beta A4 protein related 0.0066 0.0271 0.0386
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0132 0.1035
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0016 0.001
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0037 0.0266
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0107 0.2494
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Echinococcus multilocularis FTZ F1 alpha 0.0044 0.0157 0.0212
Brugia malayi Endoplasmin precursor 0.0073 0.0303 0.1273
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0141 0.1469
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0034 0.0126
Brugia malayi Doublecortin family protein 0.0065 0.0263 0.1108
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0015 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.004
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0206 0.4821
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0135 0.2843
Echinococcus multilocularis muscleblind protein 0.0298 0.1435 0.204
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0059 0.0233 0.4896
Plasmodium falciparum glutathione reductase 0.0034 0.0107 0.2494
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0157 0.0212
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0037 0.0778
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0295 0.041
Brugia malayi Hsp90 protein 0.003 0.0086 0.0364
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0133 0.1042
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0107 0.0476 1
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0132 0.1035
Brugia malayi MH2 domain containing protein 0.0018 0.0028 0.0118
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0037 0.0156
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0157 0.0212
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.0955 0.3521
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0157 0.0212
Trichomonas vaginalis heat shock protein, putative 0.0058 0.0228 0.1804
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0195
Brugia malayi RNA binding protein 0.0064 0.0259 0.109
Schistosoma mansoni hypothetical protein 0.058 0.2858 0.4082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0105
Loa Loa (eye worm) Smad1 0.0018 0.0028 0.0103
Echinococcus granulosus dna polymerase eta 0.0068 0.0277 0.0383
Mycobacterium ulcerans two component sensor kinase MprB 0.0015 0.0011 0.0011
Leishmania major hypothetical protein, conserved 0.0054 0.0206 0.2144
Schistosoma mansoni hypothetical protein 0.0024 0.0058 0.0082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0139 0.3246
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.041 0.0574
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0322 0.0459
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0157 0.0578
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0275 0.2186
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0157 0.0224
Brugia malayi hypothetical protein 0.0054 0.0206 0.0869
Trichomonas vaginalis set domain proteins, putative 0.023 0.1095 0.8793
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0107 0.2494
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.005 0.005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0556 0.2738 0.9872
Trypanosoma brucei unspecified product 0.0028 0.0078 0.1634
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0157 0.0661
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0395 0.0564
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0141 0.0595
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0157 0.0212
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0157 0.1347
Loa Loa (eye worm) hypothetical protein 0.0298 0.1435 0.5289
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0295 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0274 0.2179
Echinococcus granulosus GPCR family 2 0.0016 0.0017 0.0011
Brugia malayi ecdysone receptor 0.0021 0.004 0.017
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.008 0.0341 0.1435
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0067 0.0274 0.5766
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.026 0.1245 0.5241
Trichomonas vaginalis heat shock protein, putative 0.003 0.0086 0.0664
Loa Loa (eye worm) fli-1 protein 0.0216 0.1026 0.378
Giardia lamblia hypothetical protein 0.0067 0.0274 0.1011
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0321 0.1551 0.2206
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0157 0.0661
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0028 0.0027
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.008 0.0339 0.0473
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0299 0.1076
Loa Loa (eye worm) glutathione reductase 0.0098 0.0428 0.1578
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0107 0.2245
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0059 0.0447
Echinococcus granulosus chromobox protein 1 0.0067 0.0275 0.0381
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.041 0.0574
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.041 0.1511
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0067 0.0274 0.0392
Echinococcus multilocularis geminin 0.0686 0.3391 0.4837
Brugia malayi nuclear receptor NHR-67 0.0021 0.004 0.017
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.019 0.08
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.041 0.0586
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0053 0.0076
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0042 0.015
Loa Loa (eye worm) hypothetical protein 0.0067 0.0274 0.1011
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0484 0.2376 0.3385
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0248 0.1184 0.164
Brugia malayi Heterochromatin protein 1 0.0067 0.0275 0.1159
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Brugia malayi Blistered cuticle protein 3 0.0228 0.1086 0.4572
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.004 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0164 0.1288
Schistosoma mansoni myelin transcription factor 1 myt1 0.0107 0.0476 0.068
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Loa Loa (eye worm) hypothetical protein 0.008 0.0341 0.1256
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0067 0.0274 0.5766
Schistosoma mansoni gabp alpha 0.0071 0.0295 0.0422
Schistosoma mansoni hypothetical protein 0.0034 0.011 0.0157
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0095 0.0416 0.0583
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0058 0.0228 0.0303
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.004 0.0045
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0322 0.1185
Plasmodium falciparum heat shock protein 90, putative 0.003 0.0086 0.2017
Plasmodium falciparum plasmepsin X 0.0018 0.0028 0.0664
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0015 0.0011 0.0011
Plasmodium falciparum plasmepsin III 0.0018 0.0028 0.0664
Schistosoma mansoni cathepsin D (A01 family) 0.0077 0.0326 0.0466
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0157 0.0224
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0053 0.0063
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0042 0.0047
Brugia malayi nuclear hormone receptor 0.0044 0.0157 0.0661
Echinococcus granulosus lamin dm0 0.0031 0.0094 0.0121
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.019 0.0701
Plasmodium falciparum DNA topoisomerase 2 0.0015 0.0011 0.0255
Loa Loa (eye worm) hypothetical protein 0.0054 0.0206 0.0761
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0015 0.0011 0.023
Loa Loa (eye worm) hypothetical protein 0.0121 0.0547 0.2014
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0259 0.037
Echinococcus multilocularis voltage dependent calcium channel 0.0095 0.0416 0.0583
Leishmania major DNA polymerase eta, putative 0.0068 0.0277 0.2874
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0322 0.0447
Echinococcus multilocularis lamin dm0 0.0031 0.0094 0.0121
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0095 0.0416 0.0583
Brugia malayi steroid hormone receptor 0.0044 0.0157 0.0661
Trichomonas vaginalis MYB72, putative 0.0039 0.0132 0.1035
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0379 0.1844 0.2625
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.008 0.0339 0.0473
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.004
Mycobacterium leprae conserved hypothetical protein 0.0023 0.005 0.0055
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0107 0.0476 1
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.041 0.0586
Toxoplasma gondii DNA topoisomerase 2, putative 0.0015 0.0011 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0053 0.0195
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0037 0.0134
Schistosoma mansoni voltage-gated cation channel 0.0095 0.0416 0.0594
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0067 0.0274 0.038
Onchocerca volvulus 0.0041 0.0144 0.1223
Trypanosoma cruzi heat shock protein 85, putative 0.0058 0.0228 0.4789
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0037 0.0134
Schistosoma mansoni endoplasmin 0.0073 0.0303 0.0432
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0067 0.0274 0.5766
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Echinococcus multilocularis heat shock protein 0.0073 0.0303 0.042
Schistosoma mansoni ap endonuclease 0.004 0.0139 0.0199
Loa Loa (eye worm) thioredoxin reductase 0.0098 0.0428 0.1578
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Plasmodium falciparum plasmepsin VI 0.0077 0.0326 0.7609
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0044 0.0157 0.0224
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0103 0.0372
Loa Loa (eye worm) hypothetical protein 0.0065 0.0263 0.097
Leishmania major developmentally regulated phosphoprotein-like protein 0.0015 0.0011 0.0114
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0139 0.3328
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0395 0.0564
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Loa Loa (eye worm) hypothetical protein 0.0094 0.041 0.1511
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Trichomonas vaginalis ran, putative 0.0021 0.0042 0.0302
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.0011 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0274 0.5766
Brugia malayi hypothetical protein 0.0018 0.0028 0.012
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0095 0.0416 0.0583
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0322 0.0447
Brugia malayi nuclear hormone receptor 0.0021 0.004 0.017
Plasmodium vivax plasmepsin IV, putative 0.0077 0.0326 0.7609
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0103 0.2169
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0103 0.2169
Brugia malayi CXXC zinc finger family protein 0.0059 0.0235 0.0989
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0053 0.0076
Leishmania major heat shock protein, putative 0.003 0.0086 0.0897
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.005 0.0039
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0039 0.0132 0.1035
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0139 0.0585
Loa Loa (eye worm) hypothetical protein 0.0031 0.0091 0.0335
Echinococcus multilocularis lipoxygenase domain containing protein 0.0065 0.0263 0.0364
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0037 0.0778
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0969
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0015 0.0011 0.0011
Schistosoma mansoni zinc finger protein 0.0021 0.004 0.0058
Brugia malayi Ets-domain containing protein 0.0071 0.0295 0.1243
Schistosoma mansoni heat shock protein 0.0073 0.0303 0.0432
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0088 0.0113
Plasmodium vivax plasmepsin V, putative 0.0018 0.0028 0.0664
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.004 0.0045
Trichomonas vaginalis DNA topoisomerase II, putative 0.0015 0.0011 0.0056
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0204 0.0963 0.1365
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0552 0.2714 0.3869
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.6407
Onchocerca volvulus Dual oxidase homolog 0.0228 0.1086 0.9915
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0017 0.007
Brugia malayi Smad1 0.0018 0.0028 0.0118
Giardia lamblia DINP protein human, muc B family 0.0041 0.0141 0.0521
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0164 0.1288
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0141 0.3389
Plasmodium falciparum plasmepsin VII 0.0018 0.0028 0.0664
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0095 0.0416 0.0583
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0295 0.041
Brugia malayi Ets-domain containing protein 0.0071 0.0295 0.1243
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.1462 0.5386
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Plasmodium falciparum DNA gyrase subunit B 0.0015 0.0011 0.0255
Giardia lamblia Kinase, PLK 0.0091 0.0396 0.1459
Mycobacterium ulcerans putative regultory protein 0.0015 0.0011 0.0011
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0039 0.0132 0.3156
Schistosoma mansoni hypothetical protein 0.0686 0.3391 0.4843
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0016 0.0023
Loa Loa (eye worm) MBCTL1 0.0107 0.0476 0.1753
Echinococcus granulosus histone acetyltransferase MYST2 0.0107 0.0476 0.0668
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0157 0.0212
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.004 0.0149
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0037 0.004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Plasmodium falciparum phosphodiesterase gamma, putative 0.0067 0.0274 0.6407
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0139 0.0128
Trypanosoma brucei developmentally regulated phosphoprotein 0.0015 0.0011 0.023
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0259 0.037
Entamoeba histolytica recQ family helicase, putative 0.002 0.0037 0.0679
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.2245
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0107 0.0476 0.2002
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1435 0.7163 1
Plasmodium vivax DNA topoisomerase II, putative 0.0015 0.0011 0.0255
Schistosoma mansoni DNA topoisomerase II 0.0015 0.0011 0.0016
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Brugia malayi Importin beta-1 subunit 0.0028 0.0079 0.0334
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0067 0.0274 0.0392
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0107 0.0096
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0141 0.0521
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0139 0.0139
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.6407
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0223 0.1059 0.1465
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0552 0.2714 0.3869
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0153
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0157 0.1347
Loa Loa (eye worm) hypothetical protein 0.0061 0.0243 0.0896
Entamoeba histolytica heat shock protein 90, putative 0.0073 0.0303 0.7574
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0157 0.0224
Plasmodium vivax importin-beta 2, putative 0.0028 0.0079 0.185
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0149
Echinococcus granulosus dna polymerase kappa 0.0041 0.0141 0.019
Plasmodium falciparum plasmepsin IX 0.0018 0.0028 0.0664
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0067 0.0274 0.038
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0107 0.0476 0.0668
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0077 0.0326 0.1175
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0039 0.0132 0.3156
Brugia malayi nuclear receptor RXR 0.0021 0.004 0.017
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0107 0.014
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0058 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0141 0.2971
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.004 0.0045
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0009 0.0033
Trypanosoma brucei unspecified product 0.0028 0.0078 0.1634
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0139 0.0186
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0141 0.0202
Loa Loa (eye worm) hypothetical protein 0.0067 0.0274 0.1011
Schistosoma mansoni heat shock protein 0.003 0.0086 0.0123
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0274 0.099
Schistosoma mansoni aldehyde dehydrogenase 0.0204 0.0963 0.1375
Echinococcus granulosus lipoxygenase domain containing protein 0.0065 0.0263 0.0364
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0159 0.0215
Loa Loa (eye worm) hypothetical protein 0.0034 0.011 0.0405
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0206 0.0745
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.041 0.0586
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0033 0.0103 0.0135
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0088 0.0113
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0107 0.0385
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0157 0.0224
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.004 0.0058
Brugia malayi Nuclear hormone receptor E75 0.0021 0.004 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0042 0.0047
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.004 0.0045
Echinococcus granulosus amyloid beta A4 protein 0.0066 0.0271 0.0374
Toxoplasma gondii transporter, cation channel family protein 0.0022 0.0047 0.0168
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.1018
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0067 0.0274 0.038
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0067 0.0274 0.5766
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0045
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0107 0.045
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0039 0.0132 0.3156
Loa Loa (eye worm) aspartyl protease 6 0.0018 0.0028 0.0105
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0052 0.0388
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0067 0.0274 0.285
Schistosoma mansoni importin beta-1 0.0028 0.0079 0.0113
Loa Loa (eye worm) apoptosis regulator protein 0.008 0.0339 0.125
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0079 0.1665
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.004 0.0045
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0103 0.2169
Trypanosoma brucei polo-like protein kinase 0.0091 0.0396 0.8318
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0157 0.0212
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0042 0.0872
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0322 0.6757
Schistosoma mansoni smad1 5 8 and 0.0018 0.0028 0.004
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0059 0.0235 0.099
Loa Loa (eye worm) hypothetical protein 0.008 0.0339 0.125
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Brugia malayi aspartic protease BmAsp-1, identical 0.0018 0.0028 0.012
Plasmodium vivax heat shock protein 90, putative 0.003 0.0086 0.2017
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.5766
Brugia malayi tailless protein 0.0021 0.004 0.017
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0107 0.014
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0107 0.2245
Mycobacterium tuberculosis Probable dehydrogenase 0.0223 0.1059 0.1465
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.004 0.0272
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.004 0.017
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0015 0.0011 0.023
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0206 0.4821
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.004 0.0045
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0107 0.2245
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0015 0.0011 0.0056
Trichomonas vaginalis pc-MYB2, putative 0.0039 0.0132 0.1035
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0396 0.3158
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0018 0.0028 0.0105
Echinococcus multilocularis lipoxygenase domain containing protein 0.0065 0.0263 0.0364
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0107 0.0476 0.0668
Brugia malayi Eukaryotic aspartyl protease family protein 0.0018 0.0028 0.012
Trypanosoma cruzi heat shock protein, putative 0.003 0.0086 0.1815
Schistosoma mansoni DNA helicase recq5 0.002 0.0037 0.0053
Trypanosoma brucei Heat shock protein 83, putative 0.0073 0.0303 0.6356
Mycobacterium ulcerans two component regulator - sensor kinase 0.0015 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0028 0.0041
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0028 0.0103
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0139 0.3246
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0059 0.0233 0.4896
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0157 0.0661
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0091 0.0396 0.1459
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0059 0.0447
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0023 0.0155
Echinococcus granulosus thioredoxin glutathione reductase 0.0098 0.0428 0.06
Plasmodium falciparum thioredoxin reductase 0.0034 0.0107 0.2494
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0067 0.0274 0.038
Brugia malayi MH1 domain containing protein 0.0018 0.0028 0.0118
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.004 0.017
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0107 0.2245
Entamoeba histolytica hypothetical protein 0.0036 0.012 0.2821
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0059 0.0447
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0395 0.0552
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.004 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0157 0.0661
Brugia malayi Augmenter of liver regeneration 0.0033 0.0103 0.0435
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0012 0.0005
Brugia malayi Muscleblind-like protein 0.0298 0.1435 0.6041
Brugia malayi nuclear receptor NHR-88 0.0044 0.0157 0.0661
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0037 0.0156
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.005 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0274 0.2179
Plasmodium falciparum plasmepsin II 0.0077 0.0326 0.7609
Brugia malayi Pre-SET motif family protein 0.003 0.0088 0.0371
Schistosoma mansoni ets-related 0.0216 0.1026 0.1465
Plasmodium vivax heat shock protein, putative 0.003 0.0086 0.2017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0157 0.0578
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0015 0.0011 0.023
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0139 0.1088
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0157 0.1347
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0157 0.0661
Trichomonas vaginalis heat shock protein, putative 0.0058 0.0228 0.1804
Brugia malayi conserved hypotetical protein 0.0021 0.004 0.017
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.008 0.0339 0.0473
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Leishmania major heat shock protein 83-1 0.0073 0.0303 0.3142
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Brugia malayi hypothetical protein 0.0064 0.0257 0.1084
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0259 0.0358
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0067 0.0274 0.038
Trypanosoma brucei heat shock protein, putative 0.0073 0.0303 0.6356
Loa Loa (eye worm) hypothetical protein 0.0068 0.0277 0.102
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.004 0.017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0028 0.0194
Loa Loa (eye worm) hypothetical protein 0.0044 0.0157 0.0578
Echinococcus multilocularis microtubule associated protein 2 0.1403 0.7001 1
Brugia malayi hypothetical protein 0.0023 0.0053 0.0223
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.005 0.0039
Entamoeba histolytica Ran family GTPase 0.0021 0.0042 0.0795
Schistosoma mansoni hypothetical protein 0.008 0.0339 0.0485
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0484 0.2376 0.8754
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0274 0.2179
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0078 0.1634
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.1245 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0157 0.0224
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0322 0.1354
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0259 0.037
Schistosoma mansoni hypothetical protein 0.0413 0.2015 0.2878
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0017 0.0061
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0107 0.0107
Brugia malayi aspartic protease BmAsp-2, identical 0.0018 0.0028 0.012
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0157 0.0224
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0042 0.0969
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0795 0.6374
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0024
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0322 0.807
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0259 0.0954
Onchocerca volvulus 0.0044 0.0157 0.1347
Loa Loa (eye worm) PDE1B protein 0.0067 0.0274 0.1011
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0067 0.0274 0.038
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Schistosoma mansoni hypothetical protein 0.0686 0.3391 0.4843
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0094 0.0345
Plasmodium vivax DNA gyrase subunit B, putative 0.0015 0.0011 0.0255
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0107 0.0476 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0395 0.0552
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0039 0.0132 0.3156
Schistosoma mansoni smad1 5 8 and 0.0018 0.0028 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0157 0.0661
Toxoplasma gondii exonuclease III APE 0.004 0.0139 0.0501
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0139 0.2921
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.005 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.2245
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0044 0.0157 0.0212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0157 0.0661
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0107 0.2245
Loa Loa (eye worm) hypothetical protein 0.0107 0.0476 0.1753
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0067 0.0274 0.2179
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0157 0.0224
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0141 0.2971
Echinococcus granulosus voltage dependent calcium channel 0.0095 0.0416 0.0583
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0157 0.0224
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0141 0.1107
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0175
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0157 0.0661
Schistosoma mansoni chromobox protein 0.0067 0.0275 0.0393
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0015 0.0011 0.023
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0015 0.0011 0.0046
Trypanosoma cruzi heat shock protein 85, putative 0.0073 0.0303 0.6356
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0078 0.1634

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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