Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Papain family cysteine protease containing protein | 0.0049 | 0.1672 | 0.1672 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0092 | 0.5193 | 0.5193 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0092 | 0.5193 | 0.5193 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0063 | 0.2792 | 0.2792 |
Echinococcus granulosus | cathepsin l1 | 0.0063 | 0.2792 | 0.1345 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0092 | 0.5193 | 0.5193 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0054 | 0.2098 | 0.2098 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0092 | 0.5193 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0063 | 0.2792 | 0.2792 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0092 | 0.5193 | 0.5193 |
Brugia malayi | Cathepsin L-like precursor | 0.0092 | 0.5193 | 0.5193 |
Echinococcus multilocularis | cathepsin b | 0.015 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0063 | 0.2792 | 0.3182 |
Echinococcus granulosus | cathepsin b | 0.015 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.006 | 0.2589 | 0.2606 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0063 | 0.2792 | 0.2792 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0049 | 0.1672 | 0.1672 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0092 | 0.5193 | 0.5193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.5193 | 0.5193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Echinococcus multilocularis | cathepsin b | 0.015 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0092 | 0.5193 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.006 | 0.2589 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.015 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.006 | 0.2589 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0092 | 0.5193 | 0.5193 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0049 | 0.1672 | 0.1672 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0049 | 0.1672 | 0.1672 |
Plasmodium vivax | unspecified product | 0.0049 | 0.1672 | 0.322 |
Loa Loa (eye worm) | ctsf protein | 0.0092 | 0.5193 | 0.5193 |
Brugia malayi | Cathepsin L-like precursor | 0.0092 | 0.5193 | 0.5193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0092 | 0.5193 | 0.4228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.015 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0063 | 0.2792 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Plasmodium vivax | vivapain-1 | 0.0049 | 0.1672 | 0.322 |
Loa Loa (eye worm) | cysteine protease | 0.0092 | 0.5193 | 0.5193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0092 | 0.5193 | 0.4228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2792 | 0.2792 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0092 | 0.5193 | 0.5193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.015 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0092 | 0.5193 | 0.5193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0063 | 0.2792 | 0.2792 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0049 | 0.1672 | 0.1672 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.015 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0092 | 0.5193 | 0.5193 |
Brugia malayi | Cathepsin L-like precursor | 0.0092 | 0.5193 | 0.5193 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0092 | 0.5193 | 0.4228 |
Brugia malayi | Cytochrome P450 family protein | 0.0054 | 0.2098 | 0.2098 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0092 | 0.5193 | 0.5193 |
Echinococcus multilocularis | cysteine protease | 0.0092 | 0.5193 | 0.4228 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0092 | 0.5193 | 0.5193 |
Echinococcus multilocularis | cysteine protease | 0.0092 | 0.5193 | 0.4228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0049 | 0.1672 | 0.1672 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Leishmania major | cysteine peptidase A (CPA) | 0.0092 | 0.5193 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0092 | 0.5193 | 0.4228 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.006 | 0.2589 | 0.2589 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0092 | 0.5193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2792 | 0.2792 |
Brugia malayi | Cathepsin L-like precursor | 0.0092 | 0.5193 | 0.5193 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0092 | 0.5193 | 0.5193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0049 | 0.1672 | 0.1672 |
Loa Loa (eye worm) | cathepsin B | 0.006 | 0.2589 | 0.2589 |
Onchocerca volvulus | Cathepsin F homolog | 0.0092 | 0.5193 | 1 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0092 | 0.5193 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0092 | 0.5193 | 0.4228 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0063 | 0.2792 | 0.2792 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0092 | 0.5193 | 0.4228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.015 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0092 | 0.5193 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0063 | 0.2792 | 0.2792 |
Plasmodium vivax | vivapain-3 | 0.0049 | 0.1672 | 0.322 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0063 | 0.2792 | 0.3182 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0049 | 0.1672 | 0.1672 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0092 | 0.5193 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0092 | 0.5193 | 0.4228 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.006 | 0.2589 | 0.2606 |
Onchocerca volvulus | Cathepsin L homolog | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0092 | 0.5193 | 0.5193 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0049 | 0.1672 | 0.1672 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.006 | 0.2589 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0092 | 0.5193 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0049 | 0.1672 | 0.1672 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.015 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.006 | 0.2589 | 0.2589 |
Leishmania major | cathepsin L-like protease | 0.0092 | 0.5193 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0092 | 0.5193 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0092 | 0.5193 | 1 |
Onchocerca volvulus | 0.0092 | 0.5193 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2792 | 0.2792 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0092 | 0.5193 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.