Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.064 | 0.9524 | 0.977 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0654 | 0.9749 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0654 | 0.9749 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.