Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.1338 | 1 | 1 | |
Onchocerca volvulus | 0.1338 | 1 | 1 | |
Schistosoma mansoni | hexokinase | 0.1338 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0036 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hexokinase | 0.0414 | 0.304 | 0.304 |
Trypanosoma brucei | hexokinase | 0.1338 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.0219 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.3126 | 0.3126 |
Echinococcus granulosus | hexokinase | 0.1338 | 1 | 1 |
Leishmania major | hexokinase, putative | 0.1338 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.1338 | 1 | 0.5 |
Plasmodium vivax | hexokinase, putative | 0.1338 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1338 | 1 | 0.5 |
Echinococcus granulosus | hexokinase type 2 | 0.1338 | 1 | 1 |
Leishmania major | hexokinase, putative | 0.1338 | 1 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0036 | 0.0194 | 0.0194 |
Echinococcus multilocularis | hexokinase | 0.1338 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.1338 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.3126 | 0.3126 |
Loa Loa (eye worm) | hexokinase | 0.0839 | 0.6244 | 0.6244 |
Loa Loa (eye worm) | hypothetical protein | 0.0913 | 0.6795 | 0.6795 |
Loa Loa (eye worm) | hexokinase type II | 0.1338 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.1338 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.1338 | 1 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.1338 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.1338 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.0219 | 0.0219 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.0176 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1338 | 1 | 1 |
Entamoeba histolytica | hexokinase 2 | 0.1338 | 1 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0036 | 0.0194 | 0.0194 |
Trypanosoma brucei | hexokinase | 0.1338 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0414 | 0.304 | 0.304 |
Toxoplasma gondii | hexokinase | 0.1338 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1338 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.1338 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.0176 | 0.5 |
Brugia malayi | hexokinase type II | 0.0425 | 0.3126 | 0.3126 |
Echinococcus multilocularis | hexokinase type 2 | 0.1338 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0036 | 0.0194 | 0.0194 |
Brugia malayi | Hexokinase family protein | 0.0839 | 0.6244 | 0.6244 |
Onchocerca volvulus | 0.1338 | 1 | 1 | |
Echinococcus multilocularis | hexokinase | 0.1338 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.1338 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.1338 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.