Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0219 | 0.0399 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0399 | 0.0399 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0219 | 0.0399 | 0.5 |
Toxoplasma gondii | aminopeptidase N protein | 0.0219 | 0.0399 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.4131 | 1 | 1 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0219 | 0.0399 | 0.0399 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0219 | 0.0399 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0219 | 0.0399 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0219 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0219 | 0.0399 | 0.0399 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0219 | 0.0399 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0219 | 0.0399 | 0.5 |
Brugia malayi | TATA binding protein associated factor | 0.0219 | 0.0399 | 0.0883 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0196 | 0.0342 | 0.0342 |
Brugia malayi | hypothetical protein | 0.0219 | 0.0399 | 0.0883 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0219 | 0.0399 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0219 | 0.0399 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Brugia malayi | hypothetical protein | 0.1899 | 0.4522 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0219 | 0.0399 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0399 | 0.0399 |
Brugia malayi | Peptidase family M1 containing protein | 0.0219 | 0.0399 | 0.0883 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0214 | 0.0386 | 0.0386 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0219 | 0.0399 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0196 | 0.0342 | 0.0755 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0214 | 0.0386 | 0.0386 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.4131 | 1 | 1 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0219 | 0.0399 | 0.0399 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0196 | 0.0342 | 0.0342 |
Brugia malayi | hypothetical protein | 0.0219 | 0.0399 | 0.0883 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0219 | 0.0399 | 0.5 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0219 | 0.0399 | 0.0399 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0196 | 0.0342 | 0.0342 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Onchocerca volvulus | 0.0219 | 0.0399 | 0.5 | |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0219 | 0.0399 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0219 | 0.0399 | 0.5 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0219 | 0.0399 | 0.0399 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0219 | 0.0399 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0219 | 0.0399 | 0.0883 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0399 | 0.0399 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Loa Loa (eye worm) | aminopeptidase N | 0.0219 | 0.0399 | 0.0399 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0219 | 0.0399 | 0.5 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0219 | 0.0399 | 0.0399 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0219 | 0.0399 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0219 | 0.0399 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0219 | 0.0399 | 1 |
Trypanosoma brucei | aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0278 | 0.0278 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0219 | 0.0399 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0219 | 0.0399 | 0.5 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.4131 | 1 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0219 | 0.0399 | 0.0883 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0219 | 0.0399 | 1 |
Onchocerca volvulus | 0.0219 | 0.0399 | 0.5 | |
Echinococcus granulosus | aminopeptidase N | 0.0219 | 0.0399 | 0.0399 |
Echinococcus multilocularis | aminopeptidase N | 0.0219 | 0.0399 | 0.0399 |
Onchocerca volvulus | 0.0219 | 0.0399 | 0.5 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0219 | 0.0399 | 0.0399 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0219 | 0.0399 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.