Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0185 | 0.4304 | 0.4304 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0118 | 0 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0185 | 0.4304 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0185 | 0.4304 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0118 | 0 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0118 | 0 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0185 | 0.4304 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0118 | 0 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0185 | 0.4304 | 0.5 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0185 | 0.4304 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0185 | 0.4304 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0118 | 0 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0118 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0118 | 0 | 0.5 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0185 | 0.4304 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0185 | 0.4304 | 0.5 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0275 | 1 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0185 | 0.4304 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0118 | 0 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0185 | 0.4304 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0275 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0185 | 0.4304 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0118 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.