Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein kinase c epsilon type | 0.0198 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.014 | 0.6478 | 0.6463 |
Schistosoma mansoni | serine/threonine protein kinase | 0.014 | 0.6478 | 0.6463 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.014 | 0.6478 | 0.6463 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.014 | 0.6478 | 0.6463 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0198 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.017 | 0.8261 | 0.8254 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0078 | 0.2704 | 0.2671 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0137 | 0.6269 | 0.6253 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0198 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0137 | 0.6269 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0083 | 0.3047 | 0.3016 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0116 | 0.5039 | 0.5017 |
Toxoplasma gondii | AGC kinase | 0.0034 | 0.0044 | 0.5 |
Brugia malayi | Protein kinase c protein 2 | 0.0107 | 0.4486 | 0.4462 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4143 | 0.4117 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0198 | 1 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0057 | 0.1483 | 0.1446 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0034 | 0.0044 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0078 | 0.2704 | 0.2671 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0057 | 0.1483 | 0.1446 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.2704 | 0.2671 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0078 | 0.2704 | 0.2671 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0057 | 0.1483 | 0.1446 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0034 | 0.0044 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0116 | 0.5039 | 0.5017 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.