Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glutamate receptor NMDA | 0.0217 | 0.0233 | 0.0138 |
Echinococcus granulosus | neuroligin | 0.0203 | 0.0147 | 0.0232 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0203 | 0.0147 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1203 | 0.6357 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1203 | 0.6357 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1203 | 0.6357 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1664 | 0.9217 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0203 | 0.0147 | 0.0232 |
Echinococcus multilocularis | acetylcholinesterase | 0.1203 | 0.6357 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1203 | 0.6357 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1203 | 0.6357 | 1 |
Echinococcus multilocularis | neuroligin | 0.0203 | 0.0147 | 0.0232 |
Onchocerca volvulus | 0.0203 | 0.0147 | 0.5 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0203 | 0.0147 | 0.0232 |
Echinococcus granulosus | acetylcholinesterase | 0.1203 | 0.6357 | 1 |
Onchocerca volvulus | 0.0203 | 0.0147 | 0.5 | |
Echinococcus granulosus | nmda type glutamate receptor | 0.0213 | 0.021 | 0.033 |
Brugia malayi | Carboxylesterase family protein | 0.1203 | 0.6357 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0197 | 0.0108 | 0.0169 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.179 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0197 | 0.0108 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.1203 | 0.6357 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1203 | 0.6357 | 1 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0217 | 0.0233 | 0.0367 |
Onchocerca volvulus | 0.0203 | 0.0147 | 0.5 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0203 | 0.0147 | 0.0232 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0288 | 0.0675 | 0.085 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1203 | 0.6357 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0203 | 0.0147 | 0.0232 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0203 | 0.0147 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0203 | 0.0147 | 0.0232 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1203 | 0.6357 | 1 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0217 | 0.0233 | 0.0367 |
Echinococcus granulosus | carboxylesterase 5A | 0.1203 | 0.6357 | 1 |
Onchocerca volvulus | 0.0203 | 0.0147 | 0.5 | |
Onchocerca volvulus | 0.0203 | 0.0147 | 0.5 | |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0213 | 0.021 | 0.033 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0203 | 0.0147 | 0.0232 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.