Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ecdysone induced protein 78C | 0.0053 | 0.0162 | 0.029 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 0.5578 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0053 | 0.0162 | 0.029 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0053 | 0.0162 | 0.029 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0053 | 0.0162 | 0.029 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0053 | 0.0162 | 0.029 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0053 | 0.0162 | 0.029 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0053 | 0.0162 | 0.0166 |
Schistosoma mansoni | thyroid hormone receptor | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0053 | 0.0162 | 0.0166 |
Echinococcus granulosus | FTZ F1 alpha | 0.0053 | 0.0162 | 0.029 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0053 | 0.0162 | 0.0166 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0053 | 0.0162 | 0.029 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0053 | 0.0162 | 0.029 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.0929 | 0.08 |
Schistosoma mansoni | nuclear hormone receptor | 0.0053 | 0.0162 | 0.029 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.1149 | 0.9753 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0053 | 0.0162 | 0.0166 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.0929 | 0.1666 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.0057 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0053 | 0.0162 | 0.0166 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0053 | 0.0162 | 0.029 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | nuclear hormone receptor | 0.1149 | 0.9753 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0053 | 0.0162 | 0.0166 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | steroid hormone receptor | 0.0053 | 0.0162 | 0.0166 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0672 | 0.5578 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | nuclear receptor NHR-88 | 0.0053 | 0.0162 | 0.0166 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0139 | 0.0911 | 0.5 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0139 | 0.0911 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0053 | 0.0162 | 0.029 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0285 | 0.2185 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.0929 | 0.0953 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0053 | 0.0162 | 0.029 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.0057 | 0.0102 |
Schistosoma mansoni | coup transcription factor | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0053 | 0.0162 | 0.0166 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0026 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.0057 | 0.5 |
Brugia malayi | ecdysteroid receptor | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0053 | 0.0162 | 0.0166 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0053 | 0.0162 | 0.0166 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0053 | 0.0162 | 0.029 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0053 | 0.0162 | 0.029 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0053 | 0.0162 | 0.029 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0053 | 0.0162 | 0.029 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0285 | 0.2185 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0053 | 0.0162 | 0.029 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 0.5578 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0139 | 0.0911 | 0.5 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.0057 | 0.5 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.0894 | 0.1604 |
Brugia malayi | nuclear hormone receptor | 0.0053 | 0.0162 | 0.0166 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0053 | 0.0162 | 0.029 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0053 | 0.0162 | 0.0166 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0053 | 0.0162 | 0.029 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1124 | 0.9532 | 0.977 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0053 | 0.0162 | 0.029 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0053 | 0.0162 | 0.029 |
Schistosoma mansoni | thyroid hormone receptor | 0.0053 | 0.0162 | 0.029 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0053 | 0.0162 | 0.029 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0026 | 0.0121 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.0929 | 0.1666 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0285 | 0.2185 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.