TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 568.934 | Formula: C23H23BrClN3O3S2
H donors: 1 H acceptors: 3 LogP: 5.67 Rotable bonds: 8
Rule of 5 violations (Lipinski): 2
SMILES: Clc1cccc(c1)N1CCN(CC1)C(=O)C(NS(=O)(=O)c1ccc(s1)Br)Cc1ccccc1
InChi: 1S/C23H23BrClN3O3S2/c24-21-9-10-22(32-21)33(30,31)26-20(15-17-5-2-1-3-6-17)23(29)28-13-11-27(12-14-28)19-8-4-7-18(25)16-19/h1-10,16,20,26H,11-15H2
InChiKey: IZUWNATWZOAPIT-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	AGC/PKN protein kinase	0.0086	0.0666	0.0666
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Brugia malayi	steroid hormone receptor	0.0266	0.2794	0.2742
Schistosoma mansoni	serine/threonine protein kinase	0.0065	0.0421	0.1125
Echinococcus multilocularis	telomerase reverse transcriptase subunit	0.016	0.1539	0.4112
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0359	0.5
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0126	0.1133	0.4056
Loa Loa (eye worm)	hypothetical protein	0.0141	0.1311	0.1311
Loa Loa (eye worm)	AGC/NDR protein kinase	0.0036	0.0071	0.0071
Brugia malayi	ecdysone receptor	0.0126	0.1133	0.1069
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0126	0.1133	0.3027
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0141	0.1311	0.3502
Entamoeba histolytica	protein kinase, putative	0.0036	0.0071	0.5
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0266	0.2794	0.2742
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Loa Loa (eye worm)	hypothetical protein	0.0141	0.1311	0.1311
Loa Loa (eye worm)	hypothetical protein	0.0185	0.1829	0.1829
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Echinococcus granulosus	Ribosomal protein S6 kinase beta 2	0.0036	0.0071	0.0191
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0359	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0266	0.2794	0.2742
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0266	0.2794	0.2794
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Echinococcus granulosus	Protein kinase C brain isozyme	0.0225	0.231	0.6171
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0141	0.1311	0.3502
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Loa Loa (eye worm)	steroid hormone receptor	0.0266	0.2794	0.2794
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0266	0.2794	0.7462
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0347	0.3744	1
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0071	0.0071
Schistosoma mansoni	coup transcription factor	0.0266	0.2794	0.7462
Loa Loa (eye worm)	hypothetical protein	0.016	0.1539	0.1539
Brugia malayi	Steroid receptor seven-up type 2	0.0266	0.2794	0.2742
Brugia malayi	Protein kinase c protein 2	0.0191	0.1909	0.1851
Brugia malayi	Nuclear hormone receptor-like 1	0.0141	0.1311	0.1248
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0266	0.2794	0.7462
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0266	0.2794	0.2742
Brugia malayi	hypothetical protein	0.0141	0.1311	0.1248
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0266	0.2794	0.2742
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0266	0.2794	0.7462
Toxoplasma gondii	aldehyde dehydrogenase	0.006	0.0359	1
Echinococcus multilocularis	serine:threonine protein kinase N2	0.005	0.0245	0.0655
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0266	0.2794	0.7462
Loa Loa (eye worm)	hypothetical protein	0.0141	0.1311	0.1311
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0266	0.2794	0.7462
Loa Loa (eye worm)	DR-78	0.0126	0.1133	0.1133
Brugia malayi	tailless protein	0.0126	0.1133	0.1069
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0126	0.1133	0.3027
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0036	0.0071	0.5
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0266	0.2794	0.7462
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.0036	0.0071	0.0071
Entamoeba histolytica	protein kinase, putative	0.0036	0.0071	0.5
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Schistosoma mansoni	nuclear receptor	0.0126	0.1133	0.3027
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0266	0.2794	0.7462
Loa Loa (eye worm)	AGC/DMPK/GEK protein kinase	0.0036	0.0071	0.0071
Loa Loa (eye worm)	AGC/RSK/RSK protein kinase	0.0036	0.0071	0.0071
Schistosoma mansoni	serine/threonine protein kinase	0.0086	0.0666	0.1779
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0266	0.2794	0.7462
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0266	0.2794	0.7462
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0266	0.2794	0.2742
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0266	0.2794	0.2794
Loa Loa (eye worm)	AGC/RSK/MSK protein kinase	0.0036	0.0071	0.0071
Onchocerca volvulus	Bile acid receptor homolog	0.0266	0.2794	1
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.0359	0.096
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0266	0.2794	0.2742
Echinococcus multilocularis	serine threonine protein kinase	0.0201	0.202	0.5397
Onchocerca volvulus		0.0126	0.1133	0.4056
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0266	0.2794	0.7462
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Brugia malayi	orphan nuclear receptor NR2E1	0.0126	0.1133	0.1069
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0266	0.2794	0.7462
Schistosoma mansoni	serine/threonine kinase	0.0036	0.0071	0.0191
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0126	0.1133	0.3027
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0347	0.3744	1
Entamoeba histolytica	protein kinase, putative	0.0036	0.0071	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0266	0.2794	0.2742
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Schistosoma mansoni	zinc finger protein	0.0126	0.1133	0.3027
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Echinococcus multilocularis	RNA directed DNA polymerase	0.016	0.1539	0.4112
Echinococcus multilocularis	ecdysone induced protein 78C	0.0266	0.2794	0.7462
Brugia malayi	Hr1 repeat family protein	0.0086	0.0666	0.0599
Brugia malayi	nuclear hormone receptor	0.0266	0.2794	0.2742
Schistosoma mansoni	nuclear hormone receptor	0.0266	0.2794	0.7462
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0266	0.2794	0.7462
Echinococcus granulosus	NDR protein kinase	0.0036	0.0071	0.0191
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0266	0.2794	0.7462
Echinococcus granulosus	serine:threonine protein kinase N2	0.0086	0.0666	0.1779
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0141	0.1311	0.3502
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.0225	0.231	0.6171
Brugia malayi	nuclear receptor RXR	0.0126	0.1133	0.1069
Brugia malayi	photoreceptor-specific nuclear receptor	0.0266	0.2794	0.2742
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0266	0.2794	0.7462
Brugia malayi	Nuclear hormone receptor E75	0.0126	0.1133	0.1069
Echinococcus multilocularis	ribosomal protein S6 kinase alpha 3	0.0036	0.0071	0.0191
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0055	0.0295	0.0788
Loa Loa (eye worm)	hypothetical protein	0.0141	0.1311	0.1311
Schistosoma mansoni	thyroid hormone receptor	0.0266	0.2794	0.7462
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.006	0.0359	0.5
Echinococcus granulosus	nuclear receptor nhr 48	0.0126	0.1133	0.3027
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0036	0.0071	0.0071
Echinococcus multilocularis	nuclear receptor nhr 48	0.0126	0.1133	0.3027
Loa Loa (eye worm)	nuclear hormone receptor	0.0126	0.1133	0.1133
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0266	0.2794	0.2794
Schistosoma mansoni	atypical protein kinase C	0.006	0.0361	0.0964
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0126	0.1133	0.1069
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0266	0.2794	0.2794
Echinococcus multilocularis	FTZ F1 alpha	0.0266	0.2794	0.7462
Echinococcus granulosus	ribosomal protein s6 kinase beta 1	0.0036	0.0071	0.0191
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Onchocerca volvulus		0.0126	0.1133	0.4056
Loa Loa (eye worm)	camk/mapkapk/mnk protein kinase	0.0877	1	1
Schistosoma mansoni	serine/threonine protein kinase	0.0036	0.0071	0.0191
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0266	0.2794	0.7462
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0266	0.2794	0.2794
Schistosoma mansoni	lipoxygenase	0.0055	0.0295	0.0788
Brugia malayi	hypothetical protein	0.0126	0.1133	0.1069
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0266	0.2794	0.7462
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0126	0.1133	0.3027
Schistosoma mansoni	nuclear hormone receptor	0.0126	0.1133	0.3027
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0126	0.1133	0.1069
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Brugia malayi	nuclear hormone receptor family member odr-7	0.0126	0.1133	0.1069
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0359	0.5
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Echinococcus granulosus	RNA directed DNA polymerase	0.016	0.1539	0.4112
Brugia malayi	ecdysteroid receptor	0.0266	0.2794	0.2742
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.006	0.0359	0.5
Brugia malayi	nuclear receptor RXR	0.0141	0.1311	0.1248
Schistosoma mansoni	retinoic acid receptor RXR	0.0266	0.2794	0.7462
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.0359	0.096
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0126	0.1133	0.3027
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0126	0.1133	0.3027
Brugia malayi	nuclear receptor NHR-67	0.0126	0.1133	0.1069
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0266	0.2794	0.2742
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Onchocerca volvulus		0.0266	0.2794	1
Onchocerca volvulus	Protein ultraspiracle homolog	0.0266	0.2794	1
Brugia malayi	nuclear receptor NHR-88	0.0126	0.1133	0.1069
Echinococcus granulosus	ribosomal protein S6 kinase alpha 3	0.0036	0.0071	0.0191
Echinococcus granulosus	thyroid hormone receptor alpha	0.0126	0.1133	0.3027
Brugia malayi	protein kinase C II.	0.0065	0.0421	0.0352
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0126	0.1133	0.4056
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0266	0.2794	0.2742
Echinococcus granulosus	protein kinase C gamma type	0.0201	0.202	0.5397
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0266	0.2794	0.2742
Schistosoma mansoni	serine/threonine protein kinase	0.0225	0.231	0.6171
Echinococcus granulosus	ecdysone induced protein 78C	0.0266	0.2794	0.7462
Schistosoma mansoni	nuclear receptor nhr-48	0.0126	0.1133	0.3027
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0126	0.1133	0.1133
Brugia malayi	nuclear hormone receptor	0.0126	0.1133	0.1069
Brugia malayi	Nuclear hormone receptor E75	0.0126	0.1133	0.1069
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0266	0.2794	0.7462
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0126	0.1133	0.3027
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0126	0.1133	0.3027
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0266	0.2794	0.2794
Schistosoma mansoni	serine/threonine protein kinase	0.0036	0.0071	0.0191
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0266	0.2794	0.7462
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0347	0.3744	0.3699
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0266	0.2794	0.2794
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Entamoeba histolytica	protein kinase, putative	0.0036	0.0071	0.5
Schistosoma mansoni	nuclear receptor	0.0126	0.1133	0.3027
Schistosoma mansoni	serine/threonine protein kinase	0.0225	0.231	0.6171
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Brugia malayi	nuclear receptor NHR-88	0.0266	0.2794	0.2742
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0141	0.1311	0.3502
Brugia malayi	Nuclear hormone receptor-like 1	0.0141	0.1311	0.1248
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0065	0.0421	0.0421
Schistosoma mansoni	nuclear hormone receptor	0.0126	0.1133	0.3027
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0266	0.2794	0.2742
Echinococcus multilocularis	protein kinase c iota type	0.006	0.0361	0.0964
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.006	0.0359	0.096
Schistosoma mansoni	protein tyrosine phosphatase non-receptor type nt1	0.0347	0.3744	1
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0266	0.2794	0.2742
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0055	0.0295	0.0788
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.006	0.0359	0.096
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0086	0.0666	0.1779
Echinococcus granulosus	protein kinase c epsilon type	0.0065	0.0421	0.1125
Echinococcus granulosus	protein kinase c iota type	0.006	0.0361	0.0964
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0266	0.2794	0.7462
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0126	0.1133	0.1133
Echinococcus granulosus	FTZ F1 alpha	0.0266	0.2794	0.7462
Brugia malayi	Fes/CIP4 homology domain containing protein	0.005	0.0245	0.0175
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0126	0.1133	0.3027
Loa Loa (eye worm)	AGC/PKC/ALPHA protein kinase	0.0167	0.162	0.162
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0266	0.2794	0.2742
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0347	0.3744	0.3744
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0036	0.0071	0.0191
Schistosoma mansoni	serine/threonine protein kinase	0.0036	0.0071	0.0191
Brugia malayi	Nuclear hormone receptor-like 1	0.0266	0.2794	0.2742
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Trichomonas vaginalis	AGC family protein kinase	0.0036	0.0071	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0126	0.1133	0.3027
Schistosoma mansoni	RAR-like nuclear receptor	0.0266	0.2794	0.7462
Echinococcus multilocularis	Ribosomal protein S6 kinase beta 2	0.0036	0.0071	0.0191
Schistosoma mansoni	thyroid hormone receptor	0.0266	0.2794	0.7462
Echinococcus multilocularis	ribosomal protein s6 kinase beta 1	0.0036	0.0071	0.0191
Echinococcus multilocularis	serine:threonine protein kinase 38	0.0036	0.0071	0.0191
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0266	0.2794	1
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0126	0.1133	0.3027
Loa Loa (eye worm)	hypothetical protein	0.0141	0.1311	0.1311
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0266	0.2794	0.7462
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0266	0.2794	0.7462
Loa Loa (eye worm)	thyroid receptor interactor	0.005	0.0245	0.0245
Brugia malayi	conserved hypotetical protein	0.0126	0.1133	0.1069
Brugia malayi	hypothetical protein	0.0126	0.1133	0.1069
Echinococcus granulosus	serine:threonine protein kinase N2	0.005	0.0245	0.0655
Loa Loa (eye worm)	hypothetical protein	0.0266	0.2794	0.2794
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0141	0.1311	0.1311
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1133	0.1133
Brugia malayi	hypothetical protein	0.0141	0.1311	0.1248
Echinococcus multilocularis	protein kinase c epsilon type	0.0065	0.0421	0.1125

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 849337