Detailed information for compound 849389

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 491.582 | Formula: C27H33N5O4
  • H donors: 3 H acceptors: 5 LogP: 2.75 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1CCN(CC1)CCCNC(=O)c1ccc2c(c1)nc(c(n2)C=C(c1ccc(cc1)OC)O)O
  • InChi: 1S/C27H33N5O4/c1-3-31-13-15-32(16-14-31)12-4-11-28-26(34)20-7-10-22-23(17-20)30-27(35)24(29-22)18-25(33)19-5-8-21(36-2)9-6-19/h5-10,17-18,33H,3-4,11-16H2,1-2H3,(H,28,34)(H,30,35)
  • InChiKey: ROJGCNWHWAEDFX-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Schistosoma mansoni tyrosine kinase 0.0355 0.0585 0.0564
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0092 0.0068 0.0068
Entamoeba histolytica protein kinase, putative 0.0104 0.0092 0.0089
Schistosoma mansoni tyrosine kinase 0.0374 0.0621 0.06
Trypanosoma brucei SNF1-related protein kinases, putative 0.0107 0.0098 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0271 0.0269
Echinococcus granulosus twitchin 0.0155 0.0192 0.0182
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0374 0.0621 0.0612
Echinococcus granulosus casein kinase i 0.0127 0.0136 0.0127
Brugia malayi hypothetical protein 0.024 0.0358 0.0358
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0119 0.0121 0.0118
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0332 0.0539 0.0539
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.024 0.036 0.0351
Schistosoma mansoni vav2 0.0094 0.0071 0.0049
Echinococcus multilocularis N chimaerin 0.0086 0.0057 0.0047
Echinococcus multilocularis casein kinase I delta 0.0127 0.0136 0.0127
Brugia malayi Variant SH3 domain containing protein 0.0061 0.0007 0.0007
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0073 0.0031 0.0028
Brugia malayi probable protein kinase 0.0282 0.0442 0.0442
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0465 0.0801 0.0801
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0111 0.0106 0.0084
Echinococcus granulosus cGMP dependent protein kinase 1 0.0152 0.0187 0.0178
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0182 0.0245 0.0242
Echinococcus multilocularis epidermal growth factor receptor 0.0398 0.067 0.0661
Echinococcus multilocularis roundabout 2 0.0132 0.0147 0.0138
Echinococcus granulosus tyrosine protein kinase Blk 0.0328 0.0531 0.0522
Leishmania major protein kinase A catalytic subunit 0.0131 0.0145 0.0142
Schistosoma mansoni titin 0.0077 0.004 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0087 0.0085
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0087 0.0085
Entamoeba histolytica protein kinase domain containing protein 0.0163 0.0208 0.0205
Brugia malayi ephrin receptor 1 precursor 0.0073 0.0031 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Brugia malayi Temporarily assigned gene name protein 59 0.0128 0.014 0.014
Leishmania major protein kinase, putative 0.0171 0.0224 0.0221
Echinococcus multilocularis insulin receptor 0.0444 0.0759 0.075
Echinococcus granulosus casein kinase I alpha 0.0127 0.0136 0.0127
Echinococcus granulosus titin 0.0077 0.004 0.003
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0099 0.0083 0.0074
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0087 0.0078
Loa Loa (eye worm) protein kinase domain-containing protein 0.0171 0.0223 0.0223
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0103 0.0089 0.0086
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0089 0.0062 0.0053
Entamoeba histolytica protein kinase, putative 0.0089 0.0062 0.0059
Schistosoma mansoni serine/threonine-protein kinase 0.0182 0.0245 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0187 0.0164
Echinococcus multilocularis ephrin type A receptor 4 A 0.0107 0.0097 0.0088
Giardia lamblia Kinase, CDC7 0.0108 0.0099 0.0077
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0193 0.0267 0.0267
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0273 0.0425 0.0416
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0092 0.0069
Brugia malayi SH2 domain containing protein 0.0095 0.0074 0.0074
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0106 0.0103
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0146 0.0175 0.2895
Schistosoma mansoni protein kinase 0.0249 0.0376 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0208 0.0186
Onchocerca volvulus 0.0108 0.0099 0.0099
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0131 0.0145 0.2399
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0346 0.0324
Brugia malayi phosphoinositide-dependent protein kinase I 0.0099 0.0083 0.0083
Brugia malayi Protein kinase domain containing protein 0.0101 0.0086 0.0086
Entamoeba histolytica protein kinase , putative 0.0163 0.0208 0.0205
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0099 0.0081 0.0081
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0101 0.0086 0.0086
Trypanosoma cruzi cdc2-related kinase 3 0.018 0.0241 0.0238
Loa Loa (eye worm) TK/EPH protein kinase 0.0124 0.0131 0.0131
Leishmania major casein kinase, putative 0.0127 0.0136 0.0133
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0104 0.0092 0.0083
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0131 0.0145 0.0142
Trypanosoma cruzi aurora B kinase, putative 0.0163 0.0208 0.0205
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Schistosoma mansoni protein kinase 0.0127 0.0136 0.0114
Trichomonas vaginalis STE family protein kinase 0.0104 0.0092 0.0089
Brugia malayi Protein kinase domain 0.0104 0.0092 0.0092
Brugia malayi Protein kinase domain containing protein 0.0095 0.0074 0.0074
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0174 0.023 0.3813
Onchocerca volvulus 0.0077 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.0694 0.0673
Echinococcus multilocularis rac serine:threonine kinase 0.0182 0.0245 0.0236
Entamoeba histolytica protein kinase, putative 0.0163 0.0208 0.0205
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0131 0.0145 0.2381
Trypanosoma cruzi p21-activated kinase 3, putative 0.0073 0.0031 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0098 0.0076
Onchocerca volvulus 0.0342 0.0559 0.0559
Brugia malayi Protein kinase domain containing protein 0.2387 0.4575 0.4575
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0107 0.0098 0.0096
Echinococcus granulosus expressed protein 0.0101 0.0086 0.0077
Echinococcus granulosus Protein kinase C brain isozyme 0.025 0.0378 0.0369
Plasmodium falciparum serine/threonine protein kinase 0.0101 0.0086 0.1398
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.515 1 1
Echinococcus multilocularis c src tyrosine kinase 0.0141 0.0164 0.0155
Echinococcus granulosus N chimaerin 0.0086 0.0057 0.0047
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0249 0.0376 0.0367
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0374 0.0621 0.0612
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Brugia malayi serine/threonine-protein kinase 6 0.0163 0.0208 0.0208
Echinococcus multilocularis nervana 2 0.0123 0.0129 0.012
Toxoplasma gondii AGC kinase 0.0131 0.0145 0.2381
Leishmania major protein kinase, putative 0.0171 0.0224 0.0221
Entamoeba histolytica protein kinase, putative 0.0146 0.0175 0.0172
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0104 0.0092 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0187 0.0165
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0163 0.0207 0.0198
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0171 0.0224 0.0221
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.515 1 1
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Schistosoma mansoni growth factor receptor-bound protein 0.0098 0.0079 0.0057
Brugia malayi Protein kinase domain containing protein 0.0384 0.0641 0.0641
Schistosoma mansoni nephrin 0.0111 0.0105 0.0083
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0175 0.0231 0.0222
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0083 0.008
Brugia malayi Variant SH3 domain containing protein 0.0098 0.0079 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0224 0.0202
Loa Loa (eye worm) TK/INSR protein kinase 0.0444 0.0759 0.0759
Echinococcus multilocularis protein tyrosine kinase 0.0547 0.0962 0.0953
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0111 0.0106 0.0084
Giardia lamblia Kinase, CK1 Casein kinase 0.0127 0.0136 0.0114
Echinococcus granulosus cyclin dependent kinase 0.018 0.0241 0.0232
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0087 0.0065
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0087 0.0085
Plasmodium falciparum calcium-dependent protein kinase 3 0.0119 0.0121 0.1981
Giardia lamblia Kinase, AGC AKT 0.0135 0.0153 0.013
Schistosoma mansoni tyrosine kinase 0.0141 0.0164 0.0141
Echinococcus granulosus tyrosine protein kinase HCK 0.0276 0.0429 0.042
Schistosoma mansoni tyrosine kinase 0.0606 0.1077 0.1056
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0094 0.0072 0.007
Echinococcus multilocularis casein kinase i 0.0127 0.0136 0.0127
Echinococcus multilocularis activin receptor type 0.0094 0.0072 0.0063
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0234 0.0348 0.0348
Trypanosoma cruzi cdc2-related kinase 3 0.018 0.0241 0.0238
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0616 0.1097 0.1097
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0133 0.0149 0.0139
Plasmodium falciparum protein serine/threonine kinase-1 0.0171 0.0224 0.3715
Echinococcus multilocularis serine:threonine protein kinase N2 0.0175 0.0231 0.0222
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Echinococcus granulosus rho-associated protein kinase 1 0.0342 0.0559 0.0551
Trypanosoma cruzi casein kinase, putative 0.0127 0.0136 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0171 0.0223 0.0223
Trichomonas vaginalis STE family protein kinase 0.0103 0.0089 0.0086
Echinococcus multilocularis cyclin dependent kinase 1 0.018 0.0241 0.0232
Echinococcus granulosus titin 0.0077 0.004 0.003
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0174 0.023 0.3828
Echinococcus multilocularis protein kinase shaggy 0.0146 0.0175 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Onchocerca volvulus Serine\/threonine kinase homolog 0.0182 0.0245 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0069 0.0023 0.002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0374 0.0621 0.0612
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0411 0.0694 0.0686
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0131 0.0145 0.0142
Schistosoma mansoni serine/threonine kinase 0.0175 0.0231 0.0209
Echinococcus multilocularis serine:threonine protein kinase 0.0132 0.0147 0.0138
Giardia lamblia Kinase, CMGC GSK 0.0146 0.0175 0.0153
Echinococcus multilocularis myosin iiia 0.0103 0.0089 0.008
Schistosoma mansoni protein kinase 0.0171 0.0223 0.0201
Brugia malayi Tyrosine-protein kinase abl-1 0.022 0.0319 0.0319
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.045 0.0772 0.0763
Schistosoma mansoni adapter molecule crk 0.0098 0.0079 0.0057
Echinococcus granulosus CDC7 cell division cycle 7 0.0108 0.0099 0.009
Entamoeba histolytica protein kinase, putative 0.0089 0.0062 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0368 0.0346
Entamoeba histolytica casein kinase, putative 0.0127 0.0136 0.0133
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0131 0.0145 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0092 0.0089
Echinococcus multilocularis serine:threonine protein kinase N2 0.0304 0.0485 0.0476
Schistosoma mansoni tyrosine kinase 0.0355 0.0585 0.0564
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0259 0.0396 0.0396
Schistosoma mansoni protein kinase 0.0104 0.0092 0.0069
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0085 0.0054 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus granulosus serine:threonine protein kinase N2 0.0304 0.0485 0.0476
Schistosoma mansoni cell adhesion molecule 0.0113 0.011 0.0087
Schistosoma mansoni tyrosine kinase 0.0074 0.0033 0.001
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0152 0.0187 0.0178
Schistosoma mansoni tyrosine kinase 0.0249 0.0378 0.0356
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Onchocerca volvulus Serine\/threonine kinase homolog 0.515 1 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0095 0.0074 0.0071
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0152 0.0187 0.3089
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0175 0.0231 0.0222
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Loa Loa (eye worm) AUR protein kinase 0.0163 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0122 0.0127 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0374 0.0621 0.0612
Brugia malayi Fibronectin type III domain containing protein 0.0092 0.0068 0.0068
Onchocerca volvulus 0.0111 0.0106 0.0106
Echinococcus granulosus serine:threonine protein kinase 0.0132 0.0147 0.0138
Entamoeba histolytica protein kinase, putative 0.0099 0.0083 0.008
Brugia malayi map kinase activated protein kinase protein 2 0.0411 0.0694 0.0694
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0119 0.0121 0.1981
Echinococcus granulosus defective proboscis extension response 0.0085 0.0054 0.0045
Brugia malayi RhoGAP domain containing protein 0.0086 0.0057 0.0057
Brugia malayi Homeodomain interacting protein kinase protein 1 0.022 0.032 0.032
Echinococcus multilocularis mitogen activated protein kinase 14 0.0302 0.0482 0.0473
Loa Loa (eye worm) TK/EGFR protein kinase 0.0606 0.1077 0.1077
Echinococcus granulosus casein kinase I alpha 0.0127 0.0136 0.0127
Schistosoma mansoni protein kinase 0.0163 0.0208 0.0186
Loa Loa (eye worm) hypothetical protein 0.0089 0.0062 0.0062
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0104 0.0092 0.0083
Echinococcus granulosus protein kinase c iota type 0.0292 0.0461 0.0452
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0072 0.0028 0.0025
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.515 1 1
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Brugia malayi Fes/CIP4 homology domain containing protein 0.0117 0.0118 0.0118
Giardia lamblia Kinase, CMGC DYRK 0.0104 0.0092 0.0069
Trypanosoma cruzi cdc2-related kinase 1 0.018 0.0241 0.0238
Entamoeba histolytica protein kinase, putative 0.0104 0.0092 0.0089
Toxoplasma gondii NEK kinase 0.0069 0.0023 0.0335
Giardia lamblia Kinase, CAMK CAMKL 0.0107 0.0098 0.0076
Echinococcus multilocularis serine:threonine protein kinase 38 0.0175 0.0231 0.0222
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0119 0.0121 0.0121
Echinococcus multilocularis growth factor receptor bound protein 2 0.0098 0.0079 0.007
Echinococcus multilocularis tyrosine protein kinase Abl 0.022 0.0319 0.031
Brugia malayi Temporarily assigned gene name protein 59 0.0111 0.0106 0.0106
Echinococcus granulosus aurora kinase A 0.0163 0.0208 0.0199
Schistosoma mansoni tyrosine kinase 0.0374 0.0621 0.06
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0069 0.0023 0.002
Plasmodium falciparum serine/threonine protein kinase KIN 0.0107 0.0098 0.1605
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0099 0.0082 0.133
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0241 0.0238
Schistosoma mansoni tyrosine kinase 0.0228 0.0335 0.0313
Toxoplasma gondii AGC kinase 0.0131 0.0145 0.2381
Entamoeba histolytica protein kinase 2, putative 0.0174 0.023 0.0227
Plasmodium falciparum casein kinase 1 0.0127 0.0136 0.2238
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Brugia malayi Protein kinase domain containing protein 0.021 0.0301 0.0301
Trypanosoma cruzi casein kinase, putative 0.0127 0.0136 0.0133
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.021 0.0301 0.0292
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0086 0.0057 0.0057
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0195 0.0271 0.0271
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Brugia malayi Protein kinase domain containing protein 0.0132 0.0147 0.0147
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0094 0.0072 0.1168
Schistosoma mansoni tyrosine kinase 0.0444 0.0759 0.0738
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0241 0.0238
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus granulosus activin receptor type 0.0094 0.0072 0.0063
Echinococcus granulosus epidermal growth factor receptor 0.0398 0.067 0.0661
Loa Loa (eye worm) CDC7 protein kinase 0.0108 0.0099 0.0099
Echinococcus granulosus casein kinase I gamma 0.0171 0.0223 0.0214
Loa Loa (eye worm) hypothetical protein 0.0129 0.0141 0.0141
Brugia malayi SRC-1 0.0374 0.0621 0.0621
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0302 0.0482 0.0479
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0378 0.0356
Plasmodium vivax calcium-dependent protein kinase, putative 0.0119 0.0121 0.2
Onchocerca volvulus 0.0095 0.0074 0.0074
Onchocerca volvulus 0.0075 0.0036 0.0036
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.024 0.036 0.0351
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0092 0.0089
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0163 0.0208 0.0205
Echinococcus granulosus roundabout 2 0.0132 0.0147 0.0138
Loa Loa (eye worm) SRC-1 0.0374 0.0621 0.0621
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0135 0.0153 0.0153
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0182 0.0245 0.0245
Plasmodium falciparum serine/threonine protein kinase, putative 0.0163 0.0208 0.3447
Loa Loa (eye worm) AUR protein kinase 0.0163 0.0208 0.0208
Brugia malayi cell division control protein 2 homolog 0.018 0.0241 0.0241
Echinococcus granulosus tyrosine protein kinase Src42A 0.0374 0.0621 0.0612
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0119 0.0121 0.1981
Loa Loa (eye worm) hypothetical protein 0.0231 0.0341 0.0341
Schistosoma mansoni tyrosine kinase 0.024 0.036 0.0338
Schistosoma mansoni protein kinase 0.0082 0.0049 0.0027
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0087 0.0085
Brugia malayi Variant SH3 domain containing protein 0.0086 0.0057 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0098 0.0076
Trichomonas vaginalis STE family protein kinase 0.0104 0.0092 0.0089
Entamoeba histolytica hypothetical protein 0.0378 0.0631 0.0628
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0096 0.0076 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0301 0.0279
Echinococcus granulosus insulin receptor 0.0444 0.0759 0.075
Brugia malayi Protein kinase domain containing protein 0.0553 0.0973 0.0973
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0223 0.0201
Plasmodium vivax serine/threonine protein kinase, putative 0.0101 0.0086 0.1419
Loa Loa (eye worm) CAMK/PIM protein kinase 0.021 0.0301 0.0301
Onchocerca volvulus 0.0095 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0374 0.0621 0.0612
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0301 0.0278
Echinococcus multilocularis casein kinase I alpha 0.0127 0.0136 0.0127
Echinococcus granulosus cGMP dependent protein kinase 1 0.0152 0.0187 0.0178
Leishmania major protein kinase A catalytic subunit isoform 1 0.0131 0.0145 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0086 0.0063
Plasmodium falciparum calcium-dependent protein kinase 4 0.0119 0.0121 0.1981
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0328 0.0531 0.0522
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0119 0.0121 0.2
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.018 0.0241 0.0241
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0171 0.0224 0.0221
Loa Loa (eye worm) hypothetical protein 0.0059 0.0004 0.0004
Entamoeba histolytica cell division protein kinase 2, putative 0.018 0.0241 0.0238
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0073 0.0031 0.0031
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0163 0.0208 0.0199
Trichomonas vaginalis CK1 family protein kinase 0.0127 0.0136 0.0133
Echinococcus multilocularis Immunoglobulin 0.0085 0.0054 0.0045
Echinococcus granulosus serine:threonine protein kinase TAO1 0.024 0.0358 0.0349
Loa Loa (eye worm) CAMK protein kinase 0.0077 0.004 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0175 0.0172
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0249 0.0376 0.0367
Echinococcus granulosus protein tyrosine kinase 0.0547 0.0962 0.0953
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0101 0.0086 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0342 0.0559 0.0538
Schistosoma mansoni protein kinase 0.021 0.0301 0.0278
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0079 0.0043 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0098 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.004 0.0017
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0175 0.0231 0.0222
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0111 0.0106 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0062 0.0039
Echinococcus granulosus ephrin type A receptor 4 A 0.0107 0.0097 0.0088
Giardia lamblia Kinase, CMGC SRPK 0.0101 0.0086 0.0063
Mycobacterium ulcerans haloalkane dehalogenase 0.1662 0.3152 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0245 0.0368 0.0359
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0123 0.0129 0.012
Echinococcus multilocularis expressed protein 0.0101 0.0086 0.0077
Echinococcus multilocularis dual specificity protein kinase clk2 0.0171 0.0224 0.0215
Schistosoma mansoni tyrosine kinase 0.0398 0.067 0.0648
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0145 0.0122
Echinococcus multilocularis serine:threonine protein kinase N2 0.0129 0.0141 0.0132
Echinococcus multilocularis tyrosine protein kinase HCK 0.0276 0.0429 0.042
Brugia malayi Protein kinase domain containing protein 0.0175 0.0231 0.0231
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0384 0.0641 0.0632
Plasmodium falciparum calcium-dependent protein kinase 2 0.0119 0.0121 0.1981
Brugia malayi SH2 domain containing protein 0.0095 0.0074 0.0074
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0302 0.0482 0.0482
Onchocerca volvulus 0.0095 0.0074 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0136 0.0114
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0075 0.0036 0.0033
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0106 0.0103
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0249 0.0377 0.0377
Trypanosoma cruzi Protein kinase B 0.0182 0.0245 0.0242
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0301 0.048 0.0471
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0302 0.0482 0.0479
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0511 0.089 0.0882
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0119 0.0121 0.0112
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0119 0.0121 0.0112
Onchocerca volvulus 0.0064 0.0013 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0087 0.0085
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.021 0.0301 0.0301
Trypanosoma cruzi NIMA-related kinase, putative 0.0069 0.0023 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.515 1 1
Plasmodium falciparum cGMP-dependent protein kinase 0.0152 0.0187 0.3089
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0368 0.0346
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0077 0.004 0.004
Echinococcus granulosus growth factor receptor bound protein 2 0.0098 0.0079 0.007
Echinococcus granulosus cGMP dependent protein kinase 0.0152 0.0187 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0203 0.0286 0.0283
Echinococcus granulosus Immunoglobulin 0.0085 0.0054 0.0045
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0073 0.0031 0.0028
Entamoeba histolytica protein kinase, putative 0.0163 0.0208 0.0205
Echinococcus granulosus tyrosine protein kinase Src64B 0.0374 0.0621 0.0612
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.014 0.0163 0.016
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0171 0.0224 0.3715
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0119 0.0121 0.0112
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0119 0.0121 0.0112
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0374 0.0621 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Giardia lamblia Kinase, CMGC GSK 0.0146 0.0175 0.0153
Trypanosoma brucei protein kinase, putative 0.0094 0.0072 0.007
Schistosoma mansoni protein kinase C mu 0.0227 0.0334 0.0312
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0119 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0101 0.0087 0.0087
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0175 0.0231 0.0222
Loa Loa (eye worm) hypothetical protein 0.0098 0.0079 0.0079
Entamoeba histolytica protein kinase, putative 0.0101 0.0086 0.0083
Brugia malayi Egg laying defective protein 4 0.0152 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0142 0.0167 0.0167
Brugia malayi Immunoglobulin I-set domain containing protein 0.0632 0.113 0.113
Giardia lamblia Kinase, NEK 0.0362 0.0598 0.0577
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0087 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0121 0.0118
Echinococcus multilocularis rho associated protein kinase 0.0342 0.0559 0.0551
Loa Loa (eye worm) hypothetical protein 0.0118 0.012 0.012
Entamoeba histolytica PH domain containing protein kinase, putative 0.0182 0.0245 0.0242
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0163 0.0207 0.0198
Trypanosoma brucei polo-like protein kinase 0.515 1 1
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0352 0.0579 0.0579
Brugia malayi serine/threonine-protein kinase PAK 7 0.0249 0.0377 0.0377
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.018 0.0241 0.0241
Trypanosoma cruzi casein kinase, putative 0.0127 0.0136 0.0133
Schistosoma mansoni ste20-related kinase 0.0223 0.0325 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.022 0.032 0.0298
Entamoeba histolytica cell division protein kinase 2, putative 0.018 0.0241 0.0238
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0103 0.0089 0.0086
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Leishmania major protein kinase, putative 0.0069 0.0023 0.002
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0127 0.0136 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0245 0.0222
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0106 0.0096 0.0086
Echinococcus granulosus serine:threonine protein kinase 3 0.0274 0.0426 0.0417
Trichomonas vaginalis STE family protein kinase 0.0104 0.0092 0.0089
Plasmodium vivax protein kinase Crk2 0.018 0.0241 0.4018
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0107 0.0098 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.022 0.032 0.0317
Echinococcus granulosus serine/threonine protein kinase 0.0182 0.0245 0.0236
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Trichomonas vaginalis STE family protein kinase 0.0104 0.0092 0.0089
Schistosoma mansoni tyrosine kinase 0.0355 0.0585 0.0564
Loa Loa (eye worm) hypothetical protein 0.0111 0.0106 0.0106
Echinococcus granulosus serine:threonine protein kinase N2 0.0129 0.0141 0.0132
Schistosoma mansoni protein kinase 0.0282 0.0442 0.042
Brugia malayi Protein kinase domain containing protein 0.0616 0.1097 0.1097
Onchocerca volvulus 0.0146 0.0175 0.0175
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0069 0.0023 0.0358
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.021 0.0301 0.0301
Entamoeba histolytica protein kinase, putative 0.009 0.0064 0.0061
Echinococcus multilocularis fibroblast growth factor receptor 4 0.024 0.036 0.0351
Echinococcus multilocularis casein kinase I gamma 0.0171 0.0223 0.0214
Brugia malayi protein kinase C II. 0.021 0.0301 0.0301
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.101 0.1872 0.1864
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0141 0.0164 0.0141
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.014 0.0163 0.016
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0281 0.044 0.0431
Entamoeba histolytica protein kinase, putative 0.0306 0.0488 0.0485
Schistosoma mansoni hypothetical protein 0.0111 0.0106 0.0084
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0411 0.0694 0.0694
Brugia malayi Doublecortin family protein 0.0169 0.0219 0.0219
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0171 0.0224 0.0221
Brugia malayi Protein kinase c protein 2 0.0126 0.0135 0.0135
Giardia lamblia Kinase, NEK 0.0362 0.0598 0.0577
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0072 0.0028 0.0025
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0152 0.0187 0.0178
Echinococcus multilocularis Immunoglobulin 0.0085 0.0054 0.0045
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0384 0.0641 0.0641
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0384 0.0641 0.0632
Brugia malayi Protein kinase domain containing protein 0.0204 0.0288 0.0288
Brugia malayi Protein kinase domain containing protein 0.0444 0.0759 0.0759
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Loa Loa (eye worm) TK protein kinase 0.0328 0.0531 0.0531
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.008 0.0044 0.0035
Schistosoma mansoni tyrosine kinase 0.0095 0.0074 0.0051
Brugia malayi Protein kinase domain containing protein 0.0095 0.0074 0.0074
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0099 0.0083 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0163 0.0208 0.0205
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.024 0.0358 0.0358
Brugia malayi Tyrosine-protein kinase abl-1 0.0128 0.0138 0.0138
Echinococcus multilocularis nervana 2 0.0123 0.0129 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Echinococcus granulosus tyrosine protein kinase Fyn 0.0374 0.0621 0.0612
Toxoplasma gondii aurora kinase 0.0163 0.0208 0.3447
Plasmodium falciparum calcium-dependent protein kinase 1 0.0119 0.0121 0.1981
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0285 0.0447 0.0438
Trypanosoma cruzi polo-like protein kinase, putative 0.515 1 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.018 0.0241 0.0241
Entamoeba histolytica hypothetical protein 0.014 0.0163 0.016
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0163 0.016
Echinococcus multilocularis protein kinase c iota type 0.0292 0.0461 0.0452
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Brugia malayi Protein kinase domain containing protein 0.014 0.0163 0.0163
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0087 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.0023 0.002
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Brugia malayi serine/threonine protein kinase 6 0.0163 0.0208 0.0208
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0073 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0145 0.0122
Brugia malayi Protein kinase domain containing protein 0.0182 0.0245 0.0245
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0281 0.044 0.044
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0273 0.0425 0.0416
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0104 0.0092 0.1492
Onchocerca volvulus 0.0484 0.0837 0.0837
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0087 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0396 0.0374
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0103 0.009 0.0087
Brugia malayi Kinase associated domain 1 family protein 0.0101 0.0087 0.0087
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0411 0.0694 0.0686
Echinococcus granulosus serine:threonine protein kinase PLK1 0.515 1 1
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.014 0.0163 0.016
Loa Loa (eye worm) IKK protein kinase 0.2387 0.4575 0.4575
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.0159 0.0157
Echinococcus multilocularis mitogen activated protein kinase 11 0.0302 0.0482 0.0473
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0107 0.0098 0.1625
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0146 0.0175 0.0172
Loa Loa (eye worm) hypothetical protein 0.0085 0.0054 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Schistosoma mansoni hypothetical protein 0.0101 0.0087 0.0064
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0099 0.0083 0.0083
Schistosoma mansoni tyrosine kinase 0.0398 0.067 0.0648
Schistosoma mansoni protein kinase 0.0104 0.0092 0.0069
Echinococcus granulosus tyrosine protein kinase ABL1 0.0301 0.048 0.0471
Entamoeba histolytica p21-activated kinase 0.0112 0.0107 0.0104
Trypanosoma brucei protein kinase, putative 0.0146 0.0175 0.0172
Loa Loa (eye worm) TK/ABL protein kinase 0.0301 0.048 0.048
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0104 0.0092 0.0083
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0085 0.0054 0.0031
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0119 0.0121 0.0112
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0087 0.0085
Toxoplasma gondii NEK kinase 0.0069 0.0023 0.0335
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0103 0.0089 0.0086
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0374 0.0621 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0187 0.0165
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0162 0.0207 0.0197
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0069 0.0023 0.002
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0218 0.0316 0.0307
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0123 0.0129 0.012
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0174 0.023 0.0221
Echinococcus multilocularis tyrosine kinase 0.0095 0.0074 0.0065
Echinococcus multilocularis calcium dependent protein kinase 0.0068 0.002 0.0011
Onchocerca volvulus 0.0095 0.0074 0.0074
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0087 0.1419
Echinococcus granulosus dual specificity protein kinase clk2 0.0171 0.0224 0.0215
Echinococcus granulosus casein kinase I alpha 0.0127 0.0136 0.0127
Brugia malayi Protein kinase domain containing protein 0.008 0.0045 0.0045
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0374 0.0621 0.0612
Giardia lamblia Kinase, CMGC CDK 0.018 0.0241 0.0219
Entamoeba histolytica protein kinase, putative 0.0101 0.0086 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0119 0.0121 0.0112
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0131 0.0145 0.0142
Schistosoma mansoni tyrosine kinase 0.0141 0.0164 0.0141
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0099 0.0082 0.133
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.0023 0.002
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0162 0.0207 0.0197
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0085 0.0054 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0039 0.0016
Schistosoma mansoni protein kinase 0.045 0.0772 0.0751
Echinococcus granulosus raf serine:threonine protein kinase 0.0077 0.0039 0.003
Echinococcus multilocularis aurora kinase A 0.0163 0.0208 0.0199
Toxoplasma gondii histone kinase SNF1, putative 0.0107 0.0098 0.1605
Onchocerca volvulus 0.0095 0.0074 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0089 0.0062 0.0053
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0203 0.0287 0.0278
Brugia malayi Protein kinase domain containing protein 0.0095 0.0074 0.0074
Echinococcus multilocularis protein kinase c epsilon type 0.021 0.0301 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0098 0.0079 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0025 0.0003
Schistosoma mansoni tyrosine kinase 0.0547 0.0962 0.0941
Loa Loa (eye worm) hypothetical protein 0.0111 0.0106 0.0106
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0079 0.0043 0.004
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0171 0.0224 0.0221
Loa Loa (eye worm) TK/FAK protein kinase 0.0553 0.0973 0.0973
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0083 0.006
Schistosoma mansoni serine/threonine kinase 0.0234 0.0348 0.0326
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0398 0.067 0.0661
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0374 0.0621 0.0612
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Onchocerca volvulus 0.0095 0.0074 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0346 0.0324
Loa Loa (eye worm) hypothetical protein 0.0092 0.0068 0.0068
Echinococcus granulosus homeodomain interacting protein kinase 3 0.022 0.032 0.0311
Leishmania major protein kinase, putative 0.0103 0.0089 0.0086
Loa Loa (eye worm) AUR protein kinase 0.0163 0.0208 0.0208
Loa Loa (eye worm) TK protein kinase 0.0276 0.0429 0.0429
Trypanosoma cruzi cdc2-related kinase 1 0.018 0.0241 0.0238
Brugia malayi Hr1 repeat family protein 0.0304 0.0485 0.0485
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0101 0.0086 0.0083
Echinococcus multilocularis cyclin dependent kinase 0.018 0.0241 0.0232
Brugia malayi P38 map kinase family protein 2 0.0302 0.0482 0.0482
Echinococcus granulosus mitogen activated protein kinase 11 0.0302 0.0482 0.0473
Giardia lamblia Kinase, PLK 0.515 1 1
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0145 0.0142
Loa Loa (eye worm) AGC/NDR protein kinase 0.0175 0.0231 0.0231
Schistosoma mansoni rap gtpase-activating protein 0.0111 0.0106 0.0084
Echinococcus granulosus tyrosine protein kinase Fyn 0.0374 0.0621 0.0612
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0144 0.0171 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0241 0.0219
Brugia malayi MAP kinase sur-1 0.0102 0.0087 0.0087
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0131 0.0145 0.2381
Echinococcus multilocularis cyclin dependent kinase 1 0.018 0.0241 0.0232
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0203 0.0287 0.0287
Echinococcus granulosus mitogen activated protein kinase 14 0.0302 0.0482 0.0473
Brugia malayi Serine/threonine-protein kinase Pim-3 0.021 0.0301 0.0301
Brugia malayi hypothetical protein 0.0095 0.0074 0.0074
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0101 0.0086 0.0083
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0245 0.0368 0.0359
Giardia lamblia Kinase, CMGC CLK 0.0171 0.0224 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0231 0.0209
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0149 0.0146
Onchocerca volvulus 0.2387 0.4575 0.4575
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0233 0.0346 0.0337
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0241 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0099 0.0077
Brugia malayi Furin-like cysteine rich region family protein 0.0606 0.1077 0.1077
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0146 0.0175 0.0175
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0107 0.0098 0.0096
Plasmodium falciparum protein kinase 5 0.018 0.0241 0.4003
Onchocerca volvulus 0.0127 0.0136 0.0136
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0104 0.0092 0.0083
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0362 0.0598 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0124 0.0124
Echinococcus granulosus casein kinase I delta 0.0127 0.0136 0.0127
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0182 0.0245 0.0235
Echinococcus granulosus c src tyrosine kinase 0.0141 0.0164 0.0155
Brugia malayi intracellular kinase 0.0146 0.0175 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Brugia malayi Protein kinase domain containing protein 0.0108 0.0099 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0163 0.0208 0.0205
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0098 0.0079 0.0079
Schistosoma mansoni protein kinase 0.045 0.0772 0.0751
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.024 0.0358 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Trichomonas vaginalis CK1 family protein kinase 0.0127 0.0136 0.0133
Brugia malayi Protein kinase domain containing protein 0.0099 0.0083 0.0083
Brugia malayi hypothetical protein 0.0092 0.0068 0.0068
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0171 0.0224 0.0221
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0146 0.0175 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Echinococcus multilocularis dual specificity 0.0104 0.0092 0.0082
Echinococcus granulosus tyrosine protein kinase shark 0.0095 0.0074 0.0065
Toxoplasma gondii NEK kinase 0.0069 0.0023 0.0335
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0227 0.0334 0.0334
Echinococcus multilocularis dual specificity 0.0104 0.0092 0.0082
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.018 0.0241 0.0238
Loa Loa (eye worm) AGC/AKT protein kinase 0.0306 0.0488 0.0488
Schistosoma mansoni protein kinase 0.0249 0.0376 0.0354
Entamoeba histolytica protein kinase, putative 0.014 0.0163 0.016
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0274 0.0426 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0098 0.0076
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0127 0.0136 0.0133
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0163 0.0208 0.0205
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Brugia malayi Sex muscle abnormal protein 5 0.0098 0.0079 0.0079
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.021 0.0301 0.0292
Schistosoma mansoni growth factor receptor-bound protein 0.0098 0.0079 0.0057
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Loa Loa (eye worm) hypothetical protein 0.0107 0.0098 0.0098
Echinococcus granulosus hypothetical protein 0.012 0.0124 0.0114
Echinococcus multilocularis mitogen activated protein kinase 14 0.0302 0.0482 0.0473
Trichomonas vaginalis STE family protein kinase 0.0069 0.0023 0.002
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.018 0.0241 0.0232
Echinococcus multilocularis casein kinase I alpha 0.0127 0.0136 0.0127
Echinococcus multilocularis casein kinase I delta 0.0127 0.0136 0.0127
Echinococcus granulosus dual specificity 0.0104 0.0092 0.0082
Brugia malayi protein-tyrosine kinase 0.0328 0.0531 0.0531
Echinococcus multilocularis hypothetical protein 0.0101 0.0087 0.0078
Trypanosoma brucei protein kinase, putative 0.0102 0.0087 0.0085
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0087 0.0085
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0098 0.0079 0.0057
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0233 0.0346 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0123 0.0101
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0233 0.0346 0.0337
Onchocerca volvulus Tyrosine kinase homolog 0.0546 0.0959 0.0959
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0089 0.0062 0.0053
Trichomonas vaginalis STE family protein kinase 0.0362 0.0598 0.0596
Giardia lamblia Aurora kinase 0.0163 0.0208 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0231 0.0209
Echinococcus granulosus tyrosine protein kinase Srms 0.0095 0.0074 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0031 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.018 0.0241 0.4003
Loa Loa (eye worm) thyroid receptor interactor 0.0117 0.0118 0.0118
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0061 0.0007 0.0007
Schistosoma mansoni serine/threonine-protein kinase 0.0182 0.0245 0.0222
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0231 0.0341 0.0332
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0095 0.0074 0.0065
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0374 0.0621 0.0612
Leishmania major protein kinase, putative 0.0119 0.0121 0.0118
Entamoeba histolytica protein kinase, putative 0.0306 0.0488 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0187 0.0164
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Trypanosoma brucei NIMA-related protein kinase 0.0069 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0085 0.0054 0.0054
Echinococcus granulosus calcium dependent protein kinase 0.0068 0.002 0.0011
Echinococcus granulosus protein kinase 0.0171 0.0223 0.0214
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0233 0.0346 0.0337
Giardia lamblia Kinase, AGC PKA 0.0174 0.023 0.0208
Echinococcus multilocularis casein kinase I alpha 0.0127 0.0136 0.0127
Echinococcus granulosus cyclin dependent kinase 5 0.018 0.0241 0.0232
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0087 0.0078
Echinococcus multilocularis NCK adaptor protein 0.0098 0.0079 0.007
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Echinococcus multilocularis tyrosine protein kinase shark 0.0095 0.0074 0.0065
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0111 0.0106 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0094 0.0072 0.007
Schistosoma mansoni protein kinase 0.045 0.0772 0.0751
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.021 0.0301 0.0301
Echinococcus multilocularis titin 0.0077 0.004 0.003
Echinococcus multilocularis tyrosine protein kinase Srms 0.0328 0.0531 0.0522
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0101 0.0086 0.1398
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0094 0.0072 0.007
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.014 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0125 0.0133 0.0133
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0132 0.0147 0.0147
Echinococcus multilocularis mitogen activated protein kinase 11 0.0302 0.0482 0.0473
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0119 0.0121 0.2
Echinococcus multilocularis epidermal growth factor receptor 0.0606 0.1077 0.1068
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0378 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.515 1 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.024 0.036 0.0351
Brugia malayi Protein kinase domain containing protein 0.0095 0.0074 0.0074
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0171 0.0224 0.0224
Trypanosoma cruzi casein kinase, putative 0.0127 0.0136 0.0133
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.018 0.0241 0.0238
Echinococcus multilocularis 0.0173 0.0227 0.0218
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0451 0.0773 0.0764
Loa Loa (eye worm) hypothetical protein 0.0106 0.0096 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0092 0.0089
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0106 0.0103
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0182 0.0245 0.0235
Schistosoma mansoni ephrin receptor 0.0107 0.0097 0.0074
Echinococcus granulosus casein kinase I delta 0.0127 0.0136 0.0127
Brugia malayi Protein kinase domain containing protein 0.0195 0.0271 0.0271
Leishmania major serine/threonine-protein kinase, putative 0.0069 0.0023 0.002
Echinococcus multilocularis 0.012 0.0124 0.0114
Trypanosoma cruzi casein kinase, putative 0.0127 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0131 0.0145 0.0145
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0271 0.0269
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0127 0.0136 0.0136
Schistosoma mansoni vam6/vps39 related 0.0111 0.0106 0.0084
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0302 0.0482 0.0479
Loa Loa (eye worm) hypothetical protein 0.0459 0.079 0.079
Brugia malayi putative serine/threonine kinase SADA gamma 0.0107 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.009 0.0064 0.0061
Brugia malayi casein kinase 1, delta 0.0127 0.0136 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0358 0.0336
Loa Loa (eye worm) AGC/PKA protein kinase 0.0131 0.0145 0.0145
Echinococcus granulosus serine threonine protein kinase nrc 0.0174 0.023 0.0221
Echinococcus granulosus calcium activated potassium channel 0.0153 0.0187 0.0178
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0259 0.0396 0.0387
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.1662 0.3152 0.5
Plasmodium falciparum NIMA related kinase 4 0.0069 0.0023 0.0335
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Trypanosoma brucei casein kinase I, isoform 2 0.0127 0.0136 0.0133
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0174 0.023 0.0221
Plasmodium falciparum NIMA related kinase 1 0.0362 0.0598 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0054 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0422 0.04
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0083 0.008
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0119 0.0121 0.0121
Brugia malayi Immunoglobulin I-set domain containing protein 0.0259 0.0397 0.0397
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0632 0.113 0.113
Plasmodium vivax tyrosine kinase-like protein, putative 0.0099 0.0082 0.135
Schistosoma mansoni nck2/grb4 0.0098 0.0079 0.0057
Entamoeba histolytica protein kinase, putative 0.012 0.0123 0.012
Echinococcus granulosus NDR protein kinase 0.0175 0.0231 0.0222
Loa Loa (eye worm) CAMK/PIM protein kinase 0.021 0.0301 0.0301
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0146 0.0175 0.0175
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0298 0.0473 0.0473
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.0023 0.002
Brugia malayi Variant SH3 domain containing protein 0.0098 0.0079 0.0079
Brugia malayi Protein kinase domain containing protein 0.021 0.0301 0.0301
Onchocerca volvulus 0.0142 0.0167 0.0167
Echinococcus multilocularis CDC7 cell division cycle 7 0.0108 0.0099 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.0224 0.0221
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0099 0.0096
Brugia malayi p70 ribosomal S6 kinase beta 0.0298 0.0473 0.0473
Echinococcus granulosus tyrosine protein kinase Src42A 0.0285 0.0447 0.0438
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0104 0.0092 0.0089
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0146 0.0175 0.0153
Loa Loa (eye worm) hypothetical protein 0.0143 0.0168 0.0168
Brugia malayi Stress-activated protein kinase jnk-1 0.0281 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0092 0.0068 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0149 0.0146
Brugia malayi hypothetical protein 0.0111 0.0106 0.0106
Echinococcus granulosus dual specificity 0.0104 0.0092 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0485 0.0463
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0374 0.0621 0.0612
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0099 0.0096
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0133 0.0149 0.0139
Echinococcus multilocularis cyclin dependent kinase 5 0.018 0.0241 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0163 0.0208 0.0205
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0086 0.0057 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0163 0.014
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0104 0.0092 0.0083
Echinococcus granulosus protein kinase C gamma type 0.0216 0.0311 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0187 0.0165
Brugia malayi Protein kinase domain containing protein 0.0095 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0171 0.0224 0.0224
Echinococcus granulosus epidermal growth factor receptor 0.0606 0.1077 0.1068
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.022 0.032 0.0311
Loa Loa (eye worm) hypothetical protein 0.0616 0.1097 0.1097
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0119 0.0121 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0224 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0145 0.0122
Trypanosoma cruzi polo-like protein kinase, putative 0.515 1 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0123 0.0129 0.012
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0069 0.0023 0.002
Echinococcus multilocularis serine:threonine protein kinase 0.0132 0.0147 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0031 0.0008
Entamoeba histolytica serine/threonine protein kinase, putative 0.0069 0.0023 0.002
Entamoeba histolytica protein kinase, putative 0.0119 0.0121 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0099 0.0096
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0073 0.0031 0.0031
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0069 0.0023 0.0358
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0131 0.0145 0.0142
Schistosoma mansoni protein kinase 0.0094 0.0072 0.005
Echinococcus multilocularis death associated protein kinase 1 0.0863 0.1583 0.1575
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0169 0.0219 0.0219
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0092 0.0089
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0511 0.089 0.0882
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.008 0.0044 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0175 0.0172
Entamoeba histolytica serine/threonine protein kinase, putative 0.0107 0.0098 0.0096
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0107 0.0098 0.0089
Loa Loa (eye worm) hypothetical protein 0.0184 0.0249 0.0249
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0069 0.0023 0.002
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0174 0.0229 0.0229
Echinococcus granulosus dual specificity 0.0104 0.0092 0.0082
Echinococcus granulosus Glutaredoxin protein 5 0.0123 0.0129 0.012
Brugia malayi Protein kinase domain containing protein 0.0465 0.0801 0.0801
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Leishmania major protein kinase, putative 0.0094 0.0072 0.007
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0127 0.0136 0.0136
Trichomonas vaginalis AGC family protein kinase 0.0175 0.0231 0.0229
Schistosoma mansoni atypical protein kinase C 0.0298 0.0472 0.0451
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0131 0.0145 0.0145
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0131 0.0145 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0107 0.0098 0.0096
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0174 0.023 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0287 0.0265
Trichomonas vaginalis AGC family protein kinase 0.0163 0.0208 0.0205
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.045 0.0772 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.515 1 1
Giardia lamblia Kinase, CAMK CAMKL 0.0107 0.0098 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.0072 0.007
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.022 0.032 0.032
Giardia lamblia Kinase, STE STE20 0.0104 0.0092 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Echinococcus multilocularis dual specificity 0.014 0.0163 0.0153
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0163 0.0208 0.3463
Loa Loa (eye worm) hypothetical protein 0.0176 0.0234 0.0234
Schistosoma mansoni tyrosine kinase 0.0083 0.0051 0.0028
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0072 0.0028 0.0025
Loa Loa (eye worm) hypothetical protein 0.0132 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0142 0.0167 0.0167
Echinococcus granulosus dual specificity 0.014 0.0163 0.0153
Brugia malayi casein kinase I 0.0127 0.0136 0.0136
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0451 0.0773 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Giardia lamblia Kinase, AGC PKA 0.0131 0.0145 0.0122
Echinococcus multilocularis 0.0171 0.0223 0.0214
Loa Loa (eye worm) hypothetical protein 0.0095 0.0074 0.0074
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.014 0.0163 0.016
Trichomonas vaginalis CAMK family protein kinase 0.2543 0.4881 0.488
Entamoeba histolytica protein kinase, putative 0.0298 0.0473 0.0471
Brugia malayi protein kinase C3,putative 0.0168 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0089 0.0062 0.0062
Echinococcus multilocularis PAK box P21 Rho binding 0.0082 0.0049 0.004
Entamoeba histolytica casein kinase 1, putative 0.0127 0.0136 0.0133
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0131 0.0145 0.0142
Loa Loa (eye worm) AGC/PKA protein kinase 0.0131 0.0145 0.0145
Plasmodium vivax serine/threonine kinase-1, putative 0.0171 0.0224 0.373
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0227 0.0334 0.0334
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0099 0.0083 0.0074
Loa Loa (eye worm) AGC/PKN protein kinase 0.0304 0.0485 0.0485
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0068 0.0068
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0095 0.0074 0.0065
Brugia malayi Cam kinase protein 1 0.0119 0.0121 0.0121
Echinococcus granulosus Vam6:Vps39 protein 0.0111 0.0106 0.0097
Loa Loa (eye worm) TK/ROR protein kinase 0.0062 0.0009 0.0009
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0107 0.0098 0.0096
Schistosoma mansoni hypothetical protein 0.0101 0.0087 0.0064
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0104 0.0092 0.0092
Loa Loa (eye worm) casein kinase 0.012 0.0123 0.0123
Entamoeba histolytica protein kinase, putative 0.0276 0.0429 0.0427
Brugia malayi Serine/threonine-protein kinase SULU 0.024 0.0358 0.0358
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0104 0.0092 0.0083
Plasmodium falciparum protein kinase, putative 0.0094 0.0072 0.1168
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0087 0.0087
Brugia malayi Protein kinase domain containing protein 0.0186 0.0253 0.0253
Toxoplasma gondii casein kinase I 0.0127 0.0136 0.2238
Trypanosoma brucei rac serine-threonine kinase, putative 0.0306 0.0488 0.0485
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.0159 0.0157
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0069 0.0023 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Echinococcus granulosus neuroglian 0.0104 0.0091 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.2543 0.4881 0.488
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0259 0.0396 0.0387
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0119 0.0121 0.2
Onchocerca volvulus 0.0108 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0074 0.0032 0.0032
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0146 0.0175 0.0172
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0163 0.0208 0.0205
Trypanosoma brucei aurora B kinase 0.0163 0.0208 0.0205
Echinococcus granulosus nervana 2 0.0123 0.0129 0.012
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0142 0.0167 0.0165
Brugia malayi Protein kinase domain containing protein 0.0171 0.0223 0.0223
Entamoeba histolytica protein kinase, putative 0.0103 0.009 0.0087
Plasmodium vivax casein kinase 1, putative 0.0127 0.0136 0.2256
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0218 0.0316 0.0307
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0087 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0121 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Schistosoma mansoni kinase 0.2769 0.5325 0.5315
Echinococcus granulosus serine:threonine kinase SAD 1 0.0107 0.0098 0.0089
Brugia malayi Protein kinase domain containing protein 0.0306 0.0488 0.0488
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0175 0.0172
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0362 0.0598 1
Echinococcus granulosus NCK adaptor protein 0.0098 0.0079 0.007
Plasmodium vivax glycogen synthase kinase 3, putative 0.0146 0.0175 0.2912
Onchocerca volvulus 0.0096 0.0076 0.0076
Entamoeba histolytica protein kinase, putative 0.014 0.0163 0.016
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0103 0.0089 0.0086
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0043 0.004
Brugia malayi Protein kinase domain containing protein 0.018 0.0241 0.0241
Echinococcus multilocularis twitchin 0.007 0.0025 0.0016
Echinococcus granulosus serine:threonine protein kinase 0.0132 0.0147 0.0138
Brugia malayi STE20-like kinase MST 0.0274 0.0426 0.0426
Plasmodium falciparum NIMA related kinase 2 0.0069 0.0023 0.0335
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0146 0.0175 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0131 0.0145 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0147 0.0144
Echinococcus granulosus tyrosine kinase 0.0095 0.0074 0.0065
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0107 0.0098 0.0096
Echinococcus multilocularis dual specificity 0.0104 0.0092 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Schistosoma mansoni tyrosine kinase 0.0444 0.0759 0.0738
Entamoeba histolytica PH domain containing protein kinase, putative 0.0182 0.0245 0.0242
Echinococcus multilocularis raf serine:threonine protein kinase 0.0077 0.0039 0.003
Onchocerca volvulus 0.0099 0.0082 0.0082
Echinococcus multilocularis serine threonine protein kinase 0.0216 0.0311 0.0302
Echinococcus multilocularis expressed conserved protein 0.0152 0.0187 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0092 0.0089
Trypanosoma brucei cdc2-related kinase 1 0.018 0.0241 0.0238
Leishmania major protein kinase A catalytic subunit isoform 2 0.0131 0.0145 0.0142
Onchocerca volvulus 0.0291 0.0459 0.0459
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0087 0.0078
Plasmodium falciparum glycogen synthase kinase 3 0.0146 0.0175 0.2895
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0203 0.0287 0.0278
Loa Loa (eye worm) hypothetical protein 0.0111 0.0106 0.0106
Trichomonas vaginalis CK1 family protein kinase 0.0127 0.0136 0.0133
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0332 0.0539 0.0539
Echinococcus multilocularis tyrosine protein kinase Blk 0.0328 0.0531 0.0522
Echinococcus multilocularis neuroglian 0.0104 0.0091 0.0082
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0956 0.1766 0.1766
Trypanosoma brucei cdc2-related kinase 3 0.018 0.0241 0.0238
Schistosoma mansoni vesicular amine transporter 0.0085 0.0054 0.0031
Entamoeba histolytica protein kinase, putative 0.0175 0.0231 0.0229
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0028 0.0025
Brugia malayi C1-like domain containing protein 0.0227 0.0334 0.0334
Giardia lamblia Kinase, NEK 0.0362 0.0598 0.0577
Brugia malayi Protein kinase domain containing protein 0.0616 0.1097 0.1097
Echinococcus granulosus tyrosine kinase 0.0328 0.0531 0.0522
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0616 0.1097 0.1097
Loa Loa (eye worm) hypothetical protein 0.0175 0.0231 0.0231
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0203 0.0287 0.0287
Onchocerca volvulus 0.0176 0.0234 0.0234
Schistosoma mansoni protein kinase 0.0384 0.0641 0.0619
Loa Loa (eye worm) AGC/PKG protein kinase 0.0152 0.0187 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.004 0.004
Trichomonas vaginalis STE family protein kinase 0.0082 0.0049 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0098 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0175 0.0172
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0328 0.0531 0.0522
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0171 0.0224 0.0221
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.044 0.0419
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0104 0.0092 0.0089
Echinococcus granulosus tyrosine protein kinase Lyn 0.0425 0.0722 0.0713
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0086 0.0057 0.0034
Echinococcus multilocularis serine:threonine protein kinase 3 0.0274 0.0426 0.0417
Echinococcus granulosus c-Jun N-terminal kinases 0.0281 0.044 0.0431
Toxoplasma gondii AGC kinase 0.0298 0.0473 0.79
Loa Loa (eye worm) TK/FER protein kinase 0.0095 0.0074 0.0074
Leishmania major protein kinase, putative 0.0163 0.0208 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0241 0.0219
Loa Loa (eye worm) hypothetical protein 0.0064 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0125 0.0133 0.0133
Echinococcus granulosus cyclin dependent kinase 1 0.018 0.0241 0.0232
Echinococcus multilocularis Protein kinase C, brain isozyme 0.025 0.0378 0.0369
Brugia malayi protein unc-22 0.0077 0.004 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0092 0.0089
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0488 0.0485
Brugia malayi Protein kinase domain containing protein 0.0234 0.0348 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0083 0.008
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0104 0.0092 0.0092
Brugia malayi serine/threonine kinase 12 0.0163 0.0208 0.0208
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0163 0.0208 0.0199
Giardia lamblia Kinase, STE STE20 0.0103 0.0089 0.0067
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0086 0.0057 0.0047
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0086 0.0057 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0234 0.0348 0.0345
Echinococcus granulosus nervana 2 0.0123 0.0129 0.012
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0119 0.0121 0.1981
Brugia malayi Protein kinase domain containing protein 0.0956 0.1766 0.1766
Loa Loa (eye worm) TK protein kinase 0.0259 0.0397 0.0397
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.0023 0.002
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0059 0.0003 0.0024
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0092 0.0089
Echinococcus granulosus protein kinase c epsilon type 0.021 0.0301 0.0292
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0302 0.0482 0.0479
Loa Loa (eye worm) hypothetical protein 0.0092 0.0068 0.0068
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0089 0.0062 0.0053
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0087 0.0085
Giardia lamblia Kinase, CMGC CDK 0.018 0.0241 0.0219
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0103 0.0089 0.0086
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0374 0.0621 0.0612
Trichomonas vaginalis AGC family protein kinase 0.0362 0.0598 0.0596
Onchocerca volvulus 0.0184 0.0249 0.0249
Echinococcus multilocularis calcium activated potassium channel 0.0153 0.0187 0.0178
Entamoeba histolytica protein kinase, putative 0.0082 0.0049 0.0047
Echinococcus granulosus protein kinase shaggy 0.0146 0.0175 0.0166
Plasmodium falciparum calcium-dependent protein kinase 5 0.0119 0.0121 0.1981

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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