Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear hormone receptor | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0234 | 0.8477 | 0.8971 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0259 | 0.9449 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.022 | 0.0232 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.022 | 0.0259 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0234 | 0.8477 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.9229 | 0.9768 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.022 | 0.0259 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.022 | 0.0259 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.022 | 0.0259 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.022 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.022 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.022 | 0.0232 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.022 | 0.0259 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.022 | 0.0259 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.022 | 0.0259 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.022 | 0.0259 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.022 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.022 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.022 | 0.0232 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0234 | 0.8477 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0234 | 0.8477 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0234 | 0.8477 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0234 | 0.8477 | 0.8971 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0234 | 0.8477 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.022 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.022 | 0.0259 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.022 | 0.0259 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.022 | 0.0259 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.022 | 0.0259 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.022 | 0.0232 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.022 | 0.0232 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.022 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.022 | 0.0259 |
Brugia malayi | nuclear hormone receptor | 0.0259 | 0.9449 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.022 | 0.0259 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.022 | 0.0232 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.022 | 0.0259 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.