Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | methionine aminopeptidase | 0.0058 | 0.5106 | 0.422 |
Loa Loa (eye worm) | tyrosinase 1 | 0.009 | 0.979 | 0.979 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0058 | 0.5106 | 0.5 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.009 | 0.979 | 0.979 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0058 | 0.5106 | 0.5106 |
Onchocerca volvulus | 0.009 | 0.979 | 1 | |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0058 | 0.5106 | 0.5215 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0091 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.979 | 0.979 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0058 | 0.5106 | 0.5215 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0091 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase | 0.0091 | 1 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.009 | 0.979 | 0.979 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0058 | 0.5106 | 0.422 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0091 | 1 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0058 | 0.5106 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0091 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0058 | 0.5106 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0058 | 0.5106 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0058 | 0.5106 | 0.422 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.009 | 0.979 | 0.979 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.009 | 0.979 | 0.979 |
Onchocerca volvulus | 0.009 | 0.979 | 1 | |
Brugia malayi | ShTK domain containing protein | 0.009 | 0.979 | 0.979 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0091 | 1 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0058 | 0.5106 | 0.5 |
Onchocerca volvulus | 0.009 | 0.979 | 1 | |
Onchocerca volvulus | 0.009 | 0.979 | 1 | |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0058 | 0.5106 | 0.5 |
Schistosoma mansoni | tyrosinase precursor | 0.009 | 0.979 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.009 | 0.979 | 0.979 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0058 | 0.5106 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.979 | 0.979 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0091 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.009 | 0.979 | 0.979 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0058 | 0.5106 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0091 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.009 | 0.979 | 0.979 |
Schistosoma mansoni | tyrosinase precursor | 0.009 | 0.979 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0091 | 1 | 1 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0091 | 1 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0091 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0058 | 0.5106 | 0.422 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0091 | 1 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0058 | 0.5106 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.