Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0485 | 0.4975 | 0.4975 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0703 | 0.8807 | 1 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0224 | 0.0373 | 0.0373 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0638 | 0.7673 | 0.7673 |
Schistosoma mansoni | glutamate receptor kainate | 0.0417 | 0.3782 | 0.2764 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0485 | 0.4975 | 0.4975 |
Echinococcus granulosus | glutamate receptor 4 | 0.0377 | 0.307 | 0.307 |
Loa Loa (eye worm) | hypothetical protein | 0.0658 | 0.8027 | 0.8826 |
Echinococcus granulosus | carboxylesterase 5A | 0.0658 | 0.8027 | 0.8027 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0485 | 0.4975 | 0.4975 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0224 | 0.0373 | 0.0373 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0658 | 0.8027 | 0.8027 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0295 | 0.1621 | 0.1621 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0703 | 0.8807 | 1 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0509 | 0.5398 | 0.5398 |
Loa Loa (eye worm) | hypothetical protein | 0.0377 | 0.307 | 0.1369 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0485 | 0.4975 | 0.4975 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.077 | 1 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0417 | 0.3782 | 0.2764 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0509 | 0.5398 | 0.5398 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0485 | 0.4975 | 0.4975 |
Echinococcus multilocularis | acetylcholinesterase | 0.0658 | 0.8027 | 0.8027 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0393 | 0.3354 | 0.2034 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0658 | 0.8027 | 0.8826 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0703 | 0.8807 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0658 | 0.8027 | 0.8826 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0703 | 0.8807 | 0.8807 |
Echinococcus multilocularis | glutamate receptor 2 | 0.077 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0485 | 0.4975 | 0.4975 |
Echinococcus multilocularis | glutamate receptor 4 | 0.0377 | 0.307 | 0.307 |
Loa Loa (eye worm) | hypothetical protein | 0.0377 | 0.307 | 0.1369 |
Echinococcus multilocularis | acetylcholinesterase | 0.0658 | 0.8027 | 0.8027 |
Echinococcus multilocularis | NMDA receptor | 0.0224 | 0.0373 | 0.0373 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0325 | 0.2161 | 0.2161 |
Loa Loa (eye worm) | hypothetical protein | 0.0377 | 0.307 | 0.1369 |
Echinococcus granulosus | glutamate receptor 1 | 0.0377 | 0.307 | 0.307 |
Loa Loa (eye worm) | carboxylesterase | 0.0658 | 0.8027 | 0.8826 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0658 | 0.8027 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0658 | 0.8027 | 0.8027 |
Echinococcus granulosus | glutamate receptor 2 | 0.0638 | 0.7673 | 0.7673 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0224 | 0.0373 | 0.0373 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0325 | 0.2161 | 0.2161 |
Echinococcus granulosus | acetylcholinesterase | 0.0658 | 0.8027 | 0.8027 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.