Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0492 | 0.1173 | 0.1173 |
Trypanosoma brucei | mitogen-activated protein kinase kinase 5 | 0.017 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.291 | 1 | 1 |
Onchocerca volvulus | 0.0492 | 0.1173 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Echinococcus granulosus | acetylcholinesterase | 0.291 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.291 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.291 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Echinococcus granulosus | carboxylesterase 5A | 0.291 | 1 | 1 |
Onchocerca volvulus | 0.0492 | 0.1173 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0492 | 0.1173 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.291 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0492 | 0.1173 | 1 |
Echinococcus granulosus | neuroligin | 0.0492 | 0.1173 | 0.1173 |
Brugia malayi | Carboxylesterase family protein | 0.0492 | 0.1173 | 0.1173 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | carboxylesterase | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | carboxylesterase | 0.291 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.291 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0492 | 0.1173 | 0.1173 |
Brugia malayi | Carboxylesterase family protein | 0.0492 | 0.1173 | 0.1173 |
Brugia malayi | Carboxylesterase family protein | 0.0492 | 0.1173 | 0.1173 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0492 | 0.1173 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Trypanosoma cruzi | mitogen-activated protein kinase kinase 5 | 0.017 | 0 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0492 | 0.1173 | 0.1173 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0492 | 0.1173 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.291 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0492 | 0.1173 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0492 | 0.1173 | 0.1173 |
Leishmania major | mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 | 0.017 | 0 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0492 | 0.1173 | 0.1173 |
Giardia lamblia | Kinase, STE STE20 | 0.017 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0492 | 0.1173 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.291 | 1 | 1 |
Onchocerca volvulus | 0.0492 | 0.1173 | 0.5 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Onchocerca volvulus | 0.0492 | 0.1173 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.291 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Onchocerca volvulus | 0.0492 | 0.1173 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0492 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1173 | 0.1173 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0492 | 0.1173 | 0.1173 |
Echinococcus multilocularis | carboxylesterase 5A | 0.291 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.