Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | unspecified product | 0.0019 | 0.4504 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.4504 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.4504 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.4504 | 0.5 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.4504 | 0.4504 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.4504 | 0.4504 |
Onchocerca volvulus | 0.0027 | 1 | 0.5 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.4504 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.4504 | 0.5 |
Echinococcus granulosus | lamin | 0.0027 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.4504 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.4504 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.4504 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 1 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.4504 | 0.4504 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.4504 | 0.4504 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.4504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.9646 | 0.9646 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 1 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.4504 | 0.4504 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.1026 | 0.1026 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 1 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.4504 | 0.4504 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.4504 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 1 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.4504 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.4504 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.4504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4504 | 0.4504 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.4504 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.4504 | 0.4504 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.4504 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.4504 | 0.3875 |
Echinococcus multilocularis | lamin | 0.0027 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.4504 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.4504 | 0.3875 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.