TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 331.433 | Formula: C17H21N3O2S
H donors: 1 H acceptors: 2 LogP: 1.93 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: NC(=O)CSc1cn(c2c1cccc2)CC(=O)N1CCCCC1
InChi: 1S/C17H21N3O2S/c18-16(21)12-23-15-10-20(14-7-3-2-6-13(14)15)11-17(22)19-8-4-1-5-9-19/h2-3,6-7,10H,1,4-5,8-9,11-12H2,(H2,18,21)
InChiKey: FZJVAUIAWHATDG-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	g protein coupled receptor	0.003	0.5599	0.5599
Echinococcus granulosus	serotonin receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Echinococcus granulosus	biogenic amine 5HT receptor	0.003	0.5599	0.5599
Schistosoma mansoni	amine GPCR	0.003	0.5599	1
Echinococcus granulosus	g protein coupled receptor	0.003	0.5599	0.5599
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0042	1	0.5
Echinococcus multilocularis	G protein coupled receptor 139	0.003	0.5599	0.5599
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.003	0.5599	0.5599
Echinococcus multilocularis	serotonin receptor	0.003	0.5599	0.5599
Brugia malayi	ORL1-like opioid receptor	0.003	0.5599	0.8965
Brugia malayi	G protein-coupled receptor	0.003	0.5599	0.8965
Mycobacterium ulcerans	DNA polymerase IV	0.0042	1	0.5
Schistosoma mansoni	amine GPCR	0.003	0.5599	1
Giardia lamblia	DINP protein human, muc B family	0.0022	0.2481	0.5
Loa Loa (eye worm)	TYRA-2 protein	0.003	0.5599	0.8965
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Onchocerca volvulus		0.003	0.5599	0.5
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.003	0.5599	0.8965
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.003	0.5599	0.8965
Onchocerca volvulus		0.003	0.5599	0.5
Echinococcus granulosus	alpha 1A adrenergic receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	sulfakinin receptor protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	melatonin receptor type 1A	0.003	0.5599	0.8965
Schistosoma mansoni	biogenic amine receptor	0.003	0.5599	1
Echinococcus granulosus	tm gpcr rhodopsin	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Trypanosoma brucei	unspecified product	0.0035	0.7519	0.7519
Schistosoma mansoni	amine GPCR	0.003	0.5599	1
Echinococcus granulosus	neuropeptide Y receptor	0.003	0.5599	0.5599
Schistosoma mansoni	biogenic amine receptor	0.003	0.5599	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.003	0.5599	0.5599
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.003	0.5599	0.8965
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.003	0.5599	0.8965
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Onchocerca volvulus	Neuropeptide F receptor homolog	0.003	0.5599	0.5
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.003	0.5599	0.5599
Echinococcus granulosus	neuropeptide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Schistosoma mansoni	myosin xvIII	0.003	0.5599	1
Echinococcus multilocularis	g protein coupled receptor	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0792	0.0792
Brugia malayi	G-protein coupled receptor	0.003	0.5599	0.8965
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Echinococcus granulosus	7TM GPCR rhodopsin	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	G protein coupled receptor 139	0.003	0.5599	0.5599
Loa Loa (eye worm)	G-protein coupled receptor	0.003	0.5599	0.8965
Trypanosoma brucei	DNA polymerase IV, putative	0.0042	1	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	dro:myosuppressin receptor	0.003	0.5599	0.5599
Echinococcus granulosus	tm gpcr rhodopsin	0.003	0.5599	0.5599
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.003	0.5599	0.5599
Echinococcus granulosus	hypothetical protein	0.003	0.5599	0.5599
Echinococcus granulosus	neuropeptide Y receptor	0.003	0.5599	0.5599
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.003	0.5599	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Echinococcus granulosus	g protein coupled receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.003	0.5599	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0792	0.0792
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Echinococcus granulosus	neuropeptides capa receptor	0.003	0.5599	0.5599
Schistosoma mansoni	growth hormone secretagogue receptor	0.003	0.5599	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0042	1	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.003	0.5599	1
Echinococcus multilocularis	neuropeptide s receptor	0.003	0.5599	0.5599
Brugia malayi	Dopamine receptor protein 2	0.003	0.5599	0.8965
Schistosoma mansoni	opsin-like receptor	0.003	0.5599	1
Echinococcus multilocularis	neuropeptide Y receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	GnHR receptor homolog	0.003	0.5599	0.8965
Echinococcus multilocularis	G-protein coupled receptor, putative	0.003	0.5599	0.5599
Echinococcus multilocularis	neuropeptide Y receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0792	0.0792
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Loa Loa (eye worm)	neuropeptide F receptor	0.003	0.5599	0.8965
Echinococcus granulosus	allatostatin A receptor	0.003	0.5599	0.5599
Schistosoma mansoni	histamine h1 receptor	0.003	0.5599	1
Schistosoma mansoni	neuropeptide receptor	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	neuropeptide F-like receptor	0.003	0.5599	1
Echinococcus granulosus	sex peptide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	G-protein coupled receptor	0.003	0.5599	0.8965
Echinococcus granulosus	somatostatin receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Onchocerca volvulus		0.003	0.5599	0.5
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	larval opioid receptor	0.003	0.5599	0.8965
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0042	1	1
Echinococcus multilocularis	neuropeptide receptor A26	0.003	0.5599	0.5599
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	AKH receptor	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.003	0.5599	1
Brugia malayi	polk-prov protein	0.0032	0.6246	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	putative neuropeptide receptor	0.003	0.5599	0.8965
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0042	1	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.003	0.5599	1
Schistosoma mansoni	hypothetical protein	0.003	0.5599	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.003	0.5599	0.8965
Echinococcus granulosus	g protein coupled receptor	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Brugia malayi	putative neuropeptide receptor NPR1	0.003	0.5599	0.8965
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0022	0.2481	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Schistosoma mansoni	neuropeptide receptor	0.003	0.5599	1
Brugia malayi	Melatonin receptor type 1A	0.003	0.5599	0.8965
Echinococcus granulosus	neuropeptides capa receptor	0.003	0.5599	0.5599
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.003	0.5599	1
Echinococcus multilocularis	g-protein coupled receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	orexin receptor type 2	0.003	0.5599	0.5599
Echinococcus multilocularis	neuropeptides capa receptor	0.003	0.5599	0.5599
Leishmania major	DNA polymerase kappa, putative	0.0022	0.2481	1
Echinococcus multilocularis	neuropeptide FF receptor 2	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	amine GPCR	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Trypanosoma brucei	DNA polymerase IV, putative	0.0042	1	1
Onchocerca volvulus		0.003	0.5599	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Schistosoma mansoni	opsin-like receptor	0.003	0.5599	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.003	0.5599	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.003	0.5599	0.5599
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.003	0.5599	0.5599
Echinococcus multilocularis	dna polymerase kappa	0.0042	1	1
Echinococcus multilocularis	neuropeptide receptor	0.003	0.5599	0.5599
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Onchocerca volvulus		0.003	0.5599	0.5
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Echinococcus multilocularis	neuropeptide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Brugia malayi	G protein-coupled receptor F59B2.13	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.0032	0.6246	1
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.003	0.5599	0.5599
Brugia malayi	Dopamine receptor	0.003	0.5599	0.8965
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	peptide allatostatin:somatostatin	0.003	0.5599	0.5599
Brugia malayi	neuropeptide F receptor	0.003	0.5599	0.8965
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	serotonin receptor	0.003	0.5599	0.5599
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Echinococcus granulosus	neuropeptide s receptor	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase IV, putative	0.0035	0.7519	0.7519
Schistosoma mansoni	hypothetical protein	0.003	0.5599	1
Onchocerca volvulus		0.003	0.5599	0.5
Onchocerca volvulus		0.003	0.5599	0.5
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.003	0.5599	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.2481	0.2481
Echinococcus granulosus	neuropeptide receptor A26	0.003	0.5599	0.5599
Mycobacterium ulcerans	DNA polymerase IV	0.0042	1	0.5
Schistosoma mansoni	adenoreceptor	0.003	0.5599	1
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	dro:myosuppressin receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.003	0.5599	0.8965
Brugia malayi	RE15519p	0.003	0.5599	0.8965
Brugia malayi	Tachykinin-like peptides receptor 99D	0.003	0.5599	0.8965
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Onchocerca volvulus		0.003	0.5599	0.5
Echinococcus multilocularis	fmrfamide receptor	0.003	0.5599	0.5599
Brugia malayi	neuropeptide F receptor	0.003	0.5599	0.8965
Schistosoma mansoni	opsin-like receptor	0.003	0.5599	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	neuropeptide F receptor	0.003	0.5599	0.8965
Echinococcus granulosus	fmrfamide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.003	0.5599	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0042	1	1
Schistosoma mansoni	biogenic amine receptor	0.003	0.5599	1
Onchocerca volvulus		0.003	0.5599	0.5
Schistosoma mansoni	neuropeptide receptor	0.003	0.5599	1
Brugia malayi	Dopamine receptor protein 1	0.003	0.5599	0.8965
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Echinococcus multilocularis	sex peptide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	follicle stimulating hormone receptor	0.003	0.5599	0.8965
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0022	0.2481	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Schistosoma mansoni	neuropeptide receptor	0.003	0.5599	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.003	0.5599	1
Schistosoma mansoni	alpha-1 adrenergic receptor	0.003	0.5599	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Echinococcus granulosus	biogenic amine 5HT receptor	0.003	0.5599	0.5599
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	tm gpcr rhodopsin	0.003	0.5599	0.5599
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	orexin receptor type 2	0.003	0.5599	0.5599
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.003	0.5599	0.8965
Schistosoma mansoni	neuropeptide f receptor 76f	0.003	0.5599	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.003	0.5599	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	neuropeptides capa receptor	0.003	0.5599	0.5599
Brugia malayi	Serotonin receptor	0.003	0.5599	0.8965
Echinococcus multilocularis	g protein coupled receptor	0.003	0.5599	0.5599
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.003	0.5599	1
Onchocerca volvulus		0.003	0.5599	0.5
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.6246	0.6246
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.003	0.5599	1
Echinococcus multilocularis	somatostatin receptor	0.003	0.5599	0.5599
Schistosoma mansoni	amine GPCR	0.003	0.5599	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	allatostatin A receptor	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.003	0.5599	0.5599
Trichomonas vaginalis	DNA polymerase eta, putative	0.0042	1	0.5
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Schistosoma mansoni	neuropeptide F-like receptor	0.003	0.5599	1
Schistosoma mansoni	hypothetical protein	0.003	0.5599	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.003	0.5599	1
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	tachykinin peptides receptor 99D	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Brugia malayi	G-protein coupled receptor	0.003	0.5599	0.8965
Brugia malayi	Serotonin receptor	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus granulosus	g-protein coupled receptor	0.003	0.5599	0.5599
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.003	0.5599	0.5599
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	fmrfamide receptor	0.003	0.5599	0.5599
Trypanosoma brucei	DNA polymerase kappa, putative	0.0042	1	1
Brugia malayi	hypothetical protein	0.003	0.5599	0.8965
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.003	0.5599	0.5599
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.003	0.5599	0.8965
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.6246	0.6246
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	hypothetical protein	0.003	0.5599	0.8965
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.003	0.5599	0.8965
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.5599	0.5599
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.003	0.5599	0.5599
Onchocerca volvulus		0.003	0.5599	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.003	0.5599	0.5599
Schistosoma mansoni	hypothetical protein	0.003	0.5599	1
Echinococcus granulosus	neuropeptide receptor	0.003	0.5599	0.5599
Echinococcus granulosus	7tm_1 domain containing protein	0.003	0.5599	0.5599
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.003	0.5599	1
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.003	0.5599	0.8965
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.003	0.5599	0.5599

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 867163