Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0045 | 0.0306 | 0.0819 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0049 | 0.0354 | 0.0948 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Echinococcus multilocularis | follistatin | 0.0038 | 0.0193 | 0.0193 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0128 | 0.1556 | 0.4171 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0115 | 0.1361 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0038 | 0.0193 | 0.0516 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0128 | 0.1556 | 1 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0093 | 0.1024 | 0.3217 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0026 | 0.0068 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0069 | 0.0443 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0018 | 0.0049 |
Brugia malayi | nuclear hormone receptor | 0.0045 | 0.0306 | 0.0819 |
Trichomonas vaginalis | set domain proteins, putative | 0.0236 | 0.3183 | 0.8263 |
Onchocerca volvulus | Putative organic anion transporter | 0.0055 | 0.0459 | 0.1441 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0026 | 0.0026 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0054 | 0.0431 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0026 | 0.0026 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0055 | 0.0459 | 0.1229 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0042 | 0.0257 | 0.5 |
Onchocerca volvulus | 0.0045 | 0.0306 | 0.0961 | |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0242 | 0.3281 | 0.3281 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0026 | 0.0026 |
Brugia malayi | glutaminase DH11.1 | 0.0272 | 0.3732 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0128 | 0.1556 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0049 | 0.0354 | 0.0354 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0038 | 0.0193 | 0.1238 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0218 | 0.2919 | 0.2919 |
Echinococcus granulosus | lamin | 0.0027 | 0.0026 | 0.0026 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0038 | 0.0193 | 0.0516 |
Echinococcus granulosus | follistatin | 0.0038 | 0.0193 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0919 | 0.2463 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | coup transcription factor | 0.0045 | 0.0306 | 0.0306 |
Onchocerca volvulus | Putative organic anion transporter | 0.0055 | 0.0459 | 0.1441 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0093 | 0.1024 | 0.3217 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0069 | 0.0185 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0063 | 0.0571 | 0.1531 |
Onchocerca volvulus | 0.0055 | 0.0459 | 0.1441 | |
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.0055 | 0.0459 | 0.0459 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0069 | 0.0069 |
Echinococcus granulosus | histone deacetylase 3 | 0.0063 | 0.0571 | 0.0571 |
Echinococcus multilocularis | histone deacetylase | 0.0049 | 0.0354 | 0.0354 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0115 | 0.1361 | 1 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.0055 | 0.0459 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0051 | 0.0137 |
Trichomonas vaginalis | glutaminase, putative | 0.0272 | 0.3732 | 1 |
Giardia lamblia | DNA topoisomerase II | 0.0122 | 0.1471 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0242 | 0.3281 | 0.3281 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.275 | 0.737 |
Onchocerca volvulus | 0.0236 | 0.3183 | 1 | |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0128 | 0.1556 | 0.4171 |
Plasmodium falciparum | histone deacetylase 2 | 0.0049 | 0.0354 | 0.0744 |
Schistosoma mansoni | organic anion transporter | 0.0055 | 0.0459 | 0.0459 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0069 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0919 | 0.2463 |
Plasmodium vivax | histone deacetylase, putative | 0.0049 | 0.0354 | 0.2273 |
Leishmania major | histone deacetylase, putative | 0.0063 | 0.0571 | 0.216 |
Loa Loa (eye worm) | glutaminase | 0.0272 | 0.3732 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0055 | 0.045 | 0.045 |
Echinococcus granulosus | histone deacetylase 7 | 0.0049 | 0.0354 | 0.0354 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0055 | 0.0459 | 0.1229 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0049 | 0.0354 | 0.0354 |
Brugia malayi | prostaglandin transporter | 0.0055 | 0.0459 | 0.1229 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0045 | 0.0306 | 0.0306 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.0055 | 0.0459 | 0.0459 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0128 | 0.1556 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0045 | 0.0306 | 0.0961 |
Schistosoma mansoni | DNA topoisomerase II | 0.0128 | 0.1556 | 0.1556 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0026 | 0.0068 |
Schistosoma mansoni | lamin | 0.0027 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0063 | 0.0571 | 0.0571 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0038 | 0.0193 | 0.0516 |
Onchocerca volvulus | 0.0055 | 0.0459 | 0.1441 | |
Onchocerca volvulus | 0.0027 | 0.0026 | 0.008 | |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0045 | 0.0306 | 0.0819 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus granulosus | histone deacetylase 6 | 0.0049 | 0.0354 | 0.0354 |
Schistosoma mansoni | thyroid hormone receptor | 0.0045 | 0.0306 | 0.0306 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0063 | 0.0571 | 0.3671 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0045 | 0.0306 | 0.0819 |
Loa Loa (eye worm) | glutaminase 2 | 0.0272 | 0.3732 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0045 | 0.0306 | 0.0306 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0045 | 0.0306 | 0.0306 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0101 | 0.1143 | 0.8393 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0038 | 0.0193 | 0.0516 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0045 | 0.0306 | 0.0306 |
Plasmodium falciparum | histone deacetylase, putative | 0.0049 | 0.0354 | 0.0744 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0045 | 0.0306 | 0.0306 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0045 | 0.0306 | 0.0306 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0115 | 0.1361 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0045 | 0.0306 | 0.0306 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0026 | 0.0026 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0049 | 0.0354 | 0.0354 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0101 | 0.1143 | 0.7829 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0069 | 0.0671 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0054 | 0.0431 | 0.0431 |
Schistosoma mansoni | lipoxygenase | 0.0055 | 0.045 | 0.045 |
Loa Loa (eye worm) | sodium-independent organic anion transporter | 0.0055 | 0.0459 | 0.1229 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0045 | 0.0306 | 0.0306 |
Leishmania major | histone deacetylase, putative | 0.0063 | 0.0571 | 0.216 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0038 | 0.0193 | 0.1238 |
Brugia malayi | Histone deacetylase family protein | 0.0049 | 0.0354 | 0.0948 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0686 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0045 | 0.0306 | 0.0306 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Echinococcus granulosus | histone deacetylase | 0.0049 | 0.0354 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0476 | 0.1275 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0193 | 0.0516 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus multilocularis | agrin | 0.0038 | 0.0193 | 0.0193 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0038 | 0.0193 | 0.1238 |
Echinococcus multilocularis | expressed protein | 0.0038 | 0.0193 | 0.0193 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0045 | 0.0306 | 0.0306 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0042 | 0.0257 | 0.5 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0049 | 0.0354 | 0.0354 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0049 | 0.0354 | 0.2598 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0034 | 0.009 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0063 | 0.0571 | 0.4197 |
Brugia malayi | Histone deacetylase family protein | 0.0049 | 0.0354 | 0.0948 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0045 | 0.0306 | 0.0306 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0128 | 0.1556 | 0.3117 |
Brugia malayi | Histone deacetylase 1 | 0.0063 | 0.0571 | 0.1531 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0026 | 0.0068 |
Echinococcus granulosus | agrin | 0.0038 | 0.0193 | 0.0193 |
Onchocerca volvulus | Putative organic anion transporter | 0.0055 | 0.0459 | 0.1441 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0069 | 0.0443 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0193 | 0.0516 |
Schistosoma mansoni | glutaminase | 0.0272 | 0.3732 | 0.3732 |
Mycobacterium ulcerans | glutaminase | 0.0272 | 0.3732 | 1 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0042 | 0.0257 | 0.1652 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0049 | 0.0354 | 0.2273 |
Trypanosoma brucei | histone deacetylase 3 | 0.0049 | 0.0354 | 0.2598 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Echinococcus granulosus | histone deacetylase 1 | 0.0063 | 0.0571 | 0.0571 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0045 | 0.0306 | 0.0961 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0034 | 0.009 |
Onchocerca volvulus | 0.003 | 0.0069 | 0.0217 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0055 | 0.0459 | 0.1229 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0128 | 0.1556 | 0.1556 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0045 | 0.0306 | 0.0306 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0069 | 0.0069 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0045 | 0.0306 | 0.0819 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0045 | 0.0306 | 0.0306 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0055 | 0.045 | 0.045 |
Echinococcus granulosus | FTZ F1 alpha | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0128 | 0.1556 | 0.1556 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0063 | 0.0571 | 0.1531 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0115 | 0.1361 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0063 | 0.0571 | 0.4197 |
Brugia malayi | steroid hormone receptor | 0.0045 | 0.0306 | 0.0819 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0049 | 0.0354 | 0.0354 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0049 | 0.0354 | 0.0354 |
Brugia malayi | nuclear receptor NHR-88 | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0026 | 0.0026 |
Schistosoma mansoni | agrin | 0.0038 | 0.0193 | 0.0193 |
Plasmodium falciparum | histone deacetylase 1 | 0.0063 | 0.0571 | 0.2419 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0045 | 0.0306 | 0.0306 |
Schistosoma mansoni | histone deacetylase | 0.0063 | 0.0571 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0026 | 0.0068 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0093 | 0.1024 | 0.3217 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0055 | 0.0459 | 0.2947 |
Brugia malayi | SPARC precursor | 0.0038 | 0.0193 | 0.0516 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0049 | 0.0354 | 0.2598 |
Onchocerca volvulus | 0.0027 | 0.0026 | 0.008 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | histone deacetylase | 0.0049 | 0.0354 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Toxoplasma gondii | protease inhibitor PI2 | 0.0038 | 0.0193 | 0.1238 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0101 | 0.1143 | 0.8393 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | lamin | 0.0027 | 0.0026 | 0.0026 |
Trypanosoma brucei | histone deacetylase 1 | 0.0063 | 0.0571 | 0.4197 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0686 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0045 | 0.0306 | 0.0306 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | organic anion transporter | 0.0055 | 0.0459 | 0.0459 |
Schistosoma mansoni | nuclear hormone receptor | 0.0045 | 0.0306 | 0.0306 |
Onchocerca volvulus | 0.0055 | 0.0459 | 0.1441 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0476 | 0.1275 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0063 | 0.0571 | 0.0571 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0459 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0034 | 0.009 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0042 | 0.0257 | 0.1652 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0038 | 0.0193 | 0.1238 |
Leishmania major | DNA topoisomerase ii | 0.0115 | 0.1361 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0049 | 0.0354 | 0.2598 |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.0055 | 0.0459 | 0.0459 |
Brugia malayi | secreted modular calcium-binding protein 1 | 0.0038 | 0.0193 | 0.0516 |
Trypanosoma brucei | histone deacetylase, putative | 0.0049 | 0.0354 | 0.2598 |
Schistosoma mansoni | thyroid hormone receptor | 0.0045 | 0.0306 | 0.0306 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0045 | 0.0306 | 0.0306 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0045 | 0.0306 | 0.0819 |
Onchocerca volvulus | 0.0038 | 0.0193 | 0.0605 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0128 | 0.1556 | 0.4171 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0045 | 0.0306 | 0.0819 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0193 | 0.0516 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0101 | 0.1143 | 0.8393 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0045 | 0.0306 | 0.0819 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | kazal-type serine protease inhibitor domain-containing protein | 0.0038 | 0.0193 | 0.0516 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0063 | 0.0571 | 0.3671 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0026 | 0.0068 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0045 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0063 | 0.0571 | 0.1531 |
Trypanosoma brucei | histone deacetylase 4 | 0.0049 | 0.0354 | 0.2598 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | ecdysteroid receptor | 0.0045 | 0.0306 | 0.0819 |
Onchocerca volvulus | 0.0055 | 0.0459 | 0.1441 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0045 | 0.0306 | 0.0819 |
Loa Loa (eye worm) | agrin synaptic family protein | 0.0038 | 0.0193 | 0.0516 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.275 | 0.737 |
Brugia malayi | Probable DNA topoisomerase II | 0.0128 | 0.1556 | 0.4171 |
Trypanosoma cruzi | MFS transporter, putative | 0.0055 | 0.0459 | 0.3369 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0042 | 0.0257 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0069 | 0.0069 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0063 | 0.0571 | 0.3671 |
Schistosoma mansoni | histone deacetylase | 0.0063 | 0.0571 | 0.0571 |
Echinococcus granulosus | histone deacetylase 6 | 0.0054 | 0.0431 | 0.0431 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0063 | 0.0571 | 0.1531 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0128 | 0.1556 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0045 | 0.0306 | 0.0819 |
Schistosoma mansoni | follistatin | 0.0038 | 0.0193 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0571 | 0.1531 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0049 | 0.0354 | 0.2273 |
Onchocerca volvulus | 0.0055 | 0.0459 | 0.1441 | |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0045 | 0.0306 | 0.0961 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0193 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0306 | 0.0819 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.