Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.1054 | 0.1054 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.1054 | 0.1054 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.1054 | 0.1054 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.1054 | 0.1768 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.5431 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.1054 | 0.1768 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.5431 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.1054 | 0.1184 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.8854 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.2052 | 0.3645 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0114 | 0.0114 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2052 | 0.2052 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.1054 | 0.1054 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0114 | 0.0114 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.1054 | 0.1054 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4331 | 0.5313 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.1054 | 0.1768 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0114 | 0.0114 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.2052 | 0.3645 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.1054 | 0.1768 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.5431 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0215 | 0.0189 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4331 | 0.5313 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2052 | 0.2052 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0531 | 0.0784 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0114 | 0.0114 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.5275 | 0.5275 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.1054 | 0.1768 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.1054 | 0.1768 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2052 | 0.2052 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4619 | 0.4619 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0839 | 0.1364 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0034 | 0.5431 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.1054 | 0.1054 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0215 | 0.0127 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0839 | 0.0913 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0114 | 0.0114 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.4619 | 0.8474 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.2052 | 0.2441 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.2052 | 0.3645 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.1054 | 0.1184 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.1054 | 0.2229 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.8052 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0215 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.2052 | 0.2441 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.1054 | 0.1184 |
Onchocerca volvulus | 0.0028 | 0.4331 | 1 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.5275 | 0.6501 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0114 | 0.0114 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.5275 | 0.6501 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.1054 | 0.1054 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.1054 | 0.1768 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0784 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.2052 | 0.2441 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.5431 | 0.5 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0008 | 0.0819 | 0.0888 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.1054 | 0.1054 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.1054 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | ICD-1 protein | 0.0034 | 0.5431 | 0.6698 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0215 | 0.0127 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.1054 | 0.1768 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.1054 | 0.1184 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0034 | 0.5431 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.1054 | 0.1054 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0531 | 0.0784 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0215 | 0.0127 |
Schistosoma mansoni | transcription factor btf3 | 0.0034 | 0.5431 | 0.5431 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0034 | 0.5431 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.8052 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.5431 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0215 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0114 | 0.0114 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.2052 | 0.3645 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0034 | 0.5431 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4331 | 0.4331 |
Leishmania major | basic transcription factor 3a, putative | 0.0034 | 0.5431 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.1054 | 0.1054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Onchocerca volvulus | 0.001 | 0.1054 | 0.2229 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.1054 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.1054 | 0.1768 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.2052 | 0.3645 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.4619 | 0.8474 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.1054 | 0.2229 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0531 |
Echinococcus granulosus | transcription factor btf3 | 0.0034 | 0.5431 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0114 | 0.0114 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.5431 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.1054 | 0.1768 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0531 | 0.0784 |
Echinococcus multilocularis | transcription factor btf3 | 0.0034 | 0.5431 | 1 |
Brugia malayi | beta-NAC-like protein | 0.0034 | 0.5431 | 0.6698 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.1054 | 0.1184 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4619 | 0.4619 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.8052 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.1054 | 0.1184 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.2052 | 0.2441 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.8052 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.1054 | 0.1768 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0839 | 0.1364 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.2052 | 0.2052 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.2052 | 0.3645 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.1054 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1054 | 0.1184 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.