Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.0398 | 0.0398 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0024 | 0.0398 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.0398 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0024 | 0.0398 | 0.0398 |
Brugia malayi | Carboxylesterase family protein | 0.0141 | 0.3819 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0024 | 0.0398 | 0.0398 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Echinococcus granulosus | acetylcholinesterase | 0.0141 | 0.3819 | 1 |
Onchocerca volvulus | 0.0024 | 0.0398 | 1 | |
Onchocerca volvulus | 0.0024 | 0.0398 | 1 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0024 | 0.0398 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.3819 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | carboxylesterase | 0.0141 | 0.3819 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0141 | 0.3819 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0.0398 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0024 | 0.0398 | 0.0398 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0024 | 0.0398 | 0.1042 |
Onchocerca volvulus | 0.0024 | 0.0398 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0.0398 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.0398 | 0.1042 |
Brugia malayi | Carboxylesterase family protein | 0.0141 | 0.3819 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0141 | 0.3819 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0024 | 0.0398 | 0.1042 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0024 | 0.0398 | 0.1042 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | carboxylesterase | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.3819 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0141 | 0.3819 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0141 | 0.3819 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0024 | 0.0398 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Echinococcus multilocularis | neuroligin | 0.0024 | 0.0398 | 0.1042 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0141 | 0.3819 | 0.3819 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0024 | 0.0398 | 0.1042 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.0398 | 0.0398 |
Echinococcus granulosus | acetylcholinesterase | 0.0141 | 0.3819 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | carboxylesterase | 0.0024 | 0.0398 | 0.1042 |
Schistosoma mansoni | gliotactin | 0.0024 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0398 | 0.1042 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0141 | 0.3819 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0024 | 0.0398 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0024 | 0.0398 | 0.1042 |
Onchocerca volvulus | 0.0024 | 0.0398 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.