Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | RNA binding protein | 0.0062 | 0.1004 | 0.0804 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.005 | 0.0294 | 0.0366 |
Brugia malayi | Bromodomain containing protein | 0.0112 | 0.3853 | 0.3716 |
Trypanosoma cruzi | ISWI complex protein | 0.0045 | 0 | 0.5 |
Echinococcus multilocularis | zinc finger protein | 0.0057 | 0.0717 | 0.0592 |
Schistosoma mansoni | bromodomain containing protein | 0.0185 | 0.8037 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.1004 | 0.0804 |
Schistosoma mansoni | zinc finger protein | 0.0057 | 0.0717 | 0.0891 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0066 | 0.1214 | 0.1287 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.1004 | 0.0804 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.1004 | 0.0994 |
Loa Loa (eye worm) | PHD-finger family protein | 0.006 | 0.0894 | 0.0746 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.1004 | 0.0868 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.4581 | 0.4813 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.1004 | 0.0994 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.005 | 0.0294 | 0.0366 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1004 | 0.1249 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0894 | 0.1112 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0066 | 0.1214 | 0.151 |
Trypanosoma brucei | ISWI complex protein | 0.0045 | 0 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0066 | 0.1214 | 0.1287 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1004 | 0.1249 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0052 | 0.0397 | 0.0198 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1004 | 0.1249 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0105 | 0.3456 | 0.4427 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.005 | 0.0294 | 0.0366 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.005 | 0.0294 | 0.0366 |
Brugia malayi | PHD-finger family protein | 0.0073 | 0.161 | 0.1424 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.1004 | 0.0868 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1004 | 0.1249 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0105 | 0.3456 | 0.4427 |
Trypanosoma cruzi | ISWI complex protein | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.3864 | 0.4023 |
Loa Loa (eye worm) | hypothetical protein | 0.0206 | 0.9283 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0174 | 0.7437 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.1004 | 0.0868 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.4261 | 0.446 |
Echinococcus granulosus | zinc finger protein | 0.0057 | 0.0717 | 0.0592 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0174 | 0.7437 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1004 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0294 | 0.0085 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.