Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0117 | 0.0032 | 0.0725 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0136 | 0.0056 | 0.0043 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0117 | 0.0032 | 0.0725 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0117 | 0.0032 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0032 | 0.0018 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0117 | 0.0032 | 0.0725 |
Onchocerca volvulus | 0.0117 | 0.0032 | 1 | |
Trypanosoma brucei | aminopeptidase, putative | 0.0117 | 0.0032 | 0.0725 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0103 | 0.0014 | 0.005 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0298 | 0.0268 | 0.0254 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0117 | 0.0032 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0119 | 0.0106 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.7748 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0061 | 0.0047 |
Trypanosoma brucei | histone deacetylase 3 | 0.0164 | 0.0092 | 0.3095 |
Brugia malayi | Peptidase family M1 containing protein | 0.0117 | 0.0032 | 0.0018 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0298 | 0.0268 | 1 |
Leishmania major | histone deacetylase, putative | 0.0164 | 0.0092 | 0.2555 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0298 | 0.0268 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0164 | 0.0092 | 0.0079 |
Echinococcus granulosus | histone deacetylase 6 | 0.0164 | 0.0092 | 0.0285 |
Brugia malayi | hypothetical protein | 0.0117 | 0.0032 | 0.0018 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0184 | 0.0119 | 0.0383 |
Onchocerca volvulus | 0.0117 | 0.0032 | 1 | |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0136 | 0.0056 | 0.0043 |
Echinococcus granulosus | histone deacetylase 1 | 0.0298 | 0.0268 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0056 | 0.0043 |
Brugia malayi | TATA binding protein associated factor | 0.0117 | 0.0032 | 0.0018 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0117 | 0.0032 | 0.0725 |
Brugia malayi | Peptidase family M1 containing protein | 0.0117 | 0.0032 | 0.0018 |
Echinococcus multilocularis | aminopeptidase N | 0.0117 | 0.0032 | 0.0067 |
Echinococcus granulosus | histone deacetylase | 0.0164 | 0.0092 | 0.0285 |
Toxoplasma gondii | aminopeptidase N protein | 0.0117 | 0.0032 | 0.0725 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0298 | 0.0268 | 0.0254 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0298 | 0.0268 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.0268 | 0.0254 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0103 | 0.0014 | 0.005 |
Leishmania major | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Brugia malayi | hypothetical protein | 0.0117 | 0.0032 | 0.0018 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0184 | 0.0119 | 0.5 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0117 | 0.0032 | 0.0018 |
Echinococcus granulosus | histone deacetylase 7 | 0.0164 | 0.0092 | 0.0285 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Loa Loa (eye worm) | aminopeptidase N | 0.0117 | 0.0032 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0032 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0056 | 0.0043 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0298 | 0.0268 | 1 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0117 | 0.0032 | 0.0725 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0298 | 0.0268 | 0.0922 |
Echinococcus granulosus | histone deacetylase 3 | 0.0298 | 0.0268 | 0.0922 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0177 | 0.011 | 0.0348 |
Echinococcus granulosus | histone deacetylase 6 | 0.0164 | 0.0092 | 0.0285 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0184 | 0.0119 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0119 | 0.0106 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0117 | 0.0032 | 0.0725 |
Schistosoma mansoni | histone deacetylase | 0.0298 | 0.0268 | 0.0967 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0164 | 0.0092 | 0.3095 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0032 | 0.0018 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0164 | 0.0092 | 0.0285 |
Plasmodium falciparum | histone deacetylase, putative | 0.0164 | 0.0092 | 0.2555 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0119 | 0.0106 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0117 | 0.0032 | 0.0725 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0117 | 0.0032 | 0.0725 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0117 | 0.0032 | 0.0725 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.2212 | 0.2768 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0164 | 0.0092 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0061 | 0.0047 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0117 | 0.0032 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0061 | 0.0047 |
Entamoeba histolytica | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0117 | 0.0032 | 0.0116 |
Leishmania major | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.0164 | 0.0092 | 0.3095 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0117 | 0.0032 | 0.0116 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0184 | 0.0119 | 0.043 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0164 | 0.0092 | 0.0285 |
Onchocerca volvulus | 0.0117 | 0.0032 | 1 | |
Brugia malayi | Peptidase family M1 containing protein | 0.0117 | 0.0032 | 0.0018 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0164 | 0.0092 | 0.0285 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0298 | 0.0268 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0164 | 0.0092 | 0.0079 |
Plasmodium vivax | histone deacetylase, putative | 0.0164 | 0.0092 | 0.3095 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0164 | 0.0092 | 0.3095 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0056 | 0.0043 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0298 | 0.0268 | 1 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.2212 | 0.2768 | 0.2758 |
Brugia malayi | hypothetical protein | 0.1017 | 0.1207 | 0.1195 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0298 | 0.0268 | 0.0254 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0117 | 0.0032 | 0.0116 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0117 | 0.0032 | 0.0018 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0117 | 0.0032 | 0.0725 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0164 | 0.0092 | 0.3095 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0184 | 0.0119 | 0.0106 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0184 | 0.0119 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0056 | 0.0043 |
Brugia malayi | Histone deacetylase family protein | 0.0164 | 0.0092 | 0.0079 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0117 | 0.0032 | 0.0725 |
Schistosoma mansoni | histone deacetylase | 0.0298 | 0.0268 | 0.0967 |
Toxoplasma gondii | peptidase family M13 protein | 0.0184 | 0.0119 | 0.4153 |
Loa Loa (eye worm) | histone deacetylase | 0.0164 | 0.0092 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0061 | 0.0047 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0164 | 0.0092 | 0.3095 |
Leishmania major | histone deacetylase, putative | 0.0164 | 0.0092 | 0.2555 |
Brugia malayi | Peptidase family M13 containing protein | 0.0184 | 0.0119 | 0.0106 |
Plasmodium falciparum | histone deacetylase 2 | 0.0164 | 0.0092 | 0.2555 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0164 | 0.0092 | 0.0333 |
Brugia malayi | Histone deacetylase 1 | 0.0298 | 0.0268 | 0.0254 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0117 | 0.0032 | 0.0725 |
Trypanosoma brucei | histone deacetylase 1 | 0.0298 | 0.0268 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0298 | 0.0268 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.0164 | 0.0092 | 0.3095 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0061 | 0.0047 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.2212 | 0.2768 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0298 | 0.0268 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0061 | 0.0047 |
Giardia lamblia | Histone deacetylase | 0.0298 | 0.0268 | 0.5 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0298 | 0.0268 | 0.0254 |
Echinococcus granulosus | aminopeptidase N | 0.0117 | 0.0032 | 0.0067 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0117 | 0.0032 | 0.0067 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0298 | 0.0268 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0298 | 0.0268 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0117 | 0.0032 | 0.0116 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0164 | 0.0092 | 0.3095 |
Echinococcus granulosus | histone deacetylase 6 | 0.0177 | 0.011 | 0.0348 |
Echinococcus multilocularis | histone deacetylase | 0.0164 | 0.0092 | 0.0285 |
Plasmodium falciparum | histone deacetylase 1 | 0.0298 | 0.0268 | 1 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0184 | 0.0119 | 0.0383 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0117 | 0.0032 | 0.0725 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0177 | 0.011 | 0.0396 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.2212 | 0.2768 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.