Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0033 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.4021 | 0.2941 |
Schistosoma mansoni | pol-related | 0.0033 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.4021 | 0.2941 |
Giardia lamblia | Aldose reductase | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.4021 | 0.2941 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.4021 | 0.2941 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 1 | 1 |
Brugia malayi | flavodoxin family protein | 0.0026 | 0.6678 | 0.6078 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Leishmania major | p450 reductase, putative | 0.0026 | 0.6678 | 0.3153 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0033 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.4021 | 0.2941 |
Mycobacterium ulcerans | oxidoreductase | 0.0033 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0026 | 0.6678 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0033 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0033 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.4021 | 0.4021 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.4021 | 0.2941 |
Onchocerca volvulus | 0.0033 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Brugia malayi | FAD binding domain containing protein | 0.0026 | 0.6678 | 0.6078 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.4021 | 0.2941 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.6678 | 0.6078 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.4021 | 0.2941 |
Trypanosoma cruzi | aldo-keto reductase | 0.0033 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.4021 | 0.4021 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.4021 | 0.2941 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0026 | 0.6678 | 0.6078 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.4021 | 0.2941 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0033 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.4021 | 0.2941 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0033 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 1 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.4021 | 0.2941 |
Onchocerca volvulus | 0.0033 | 1 | 1 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0016 | 0.153 | 0.153 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0033 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.4021 | 0.2941 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0026 | 0.6678 | 0.6078 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | aldehyde reductase | 0.0023 | 0.514 | 0.4262 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 1 | 1 | |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.4021 | 0.4021 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.4021 | 0.2941 |
Onchocerca volvulus | 0.0033 | 1 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.4021 | 0.2941 |
Onchocerca volvulus | 0.0033 | 1 | 1 | |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0023 | 0.514 | 0.4262 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.4021 | 0.2941 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.4021 | 0.2941 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.4021 | 0.4021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.4021 | 0.2941 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0026 | 0.6678 | 0.3153 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.4021 | 0.4021 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.4021 | 0.4021 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.4021 | 0.4021 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.4021 | 0.4021 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.4021 | 0.2941 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.4021 | 0.4021 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.4021 | 0.2941 |
Chlamydia trachomatis | sulfite reductase | 0.0016 | 0.153 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0026 | 0.6678 | 0.6078 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.4021 | 0.2941 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.4021 | 0.2941 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0026 | 0.6678 | 0.6078 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.4021 | 0.4021 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0033 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0033 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.4021 | 0.2941 |
Giardia lamblia | Aldose reductase | 0.0033 | 1 | 1 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0026 | 0.6678 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0033 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.4021 | 0.4021 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.4021 | 0.4021 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.4021 | 0.2941 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.4021 | 0.2941 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.4021 | 0.4021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.4021 | 0.2941 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.4021 | 0.2941 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0026 | 0.6678 | 0.6078 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.4021 | 0.2941 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0026 | 0.6678 | 0.6678 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0026 | 0.6678 | 0.3153 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.