Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aminopeptidase N | 0.0174 | 0.0105 | 0.0226 |
Entamoeba histolytica | aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0174 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0002 | 0.0002 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0174 | 0.0105 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Brugia malayi | Peptidase family M1 containing protein | 0.0174 | 0.0105 | 0.0076 |
Onchocerca volvulus | 0.0174 | 0.0105 | 0.5 | |
Trypanosoma brucei | aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0174 | 0.0105 | 0.5 |
Brugia malayi | hypothetical protein | 0.1505 | 0.1523 | 0.1499 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0102 | 0.0028 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0174 | 0.0105 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0174 | 0.0105 | 1 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.3274 | 0.3407 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0174 | 0.0105 | 0.5 |
Brugia malayi | hypothetical protein | 0.0174 | 0.0105 | 0.0076 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0174 | 0.0105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0002 | 0.0002 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.3274 | 0.3407 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0174 | 0.0105 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Onchocerca volvulus | 0.0174 | 0.0105 | 0.5 | |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0174 | 0.0105 | 0.0226 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0174 | 0.0105 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0174 | 0.0105 | 0.0226 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0174 | 0.0105 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0174 | 0.0105 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0174 | 0.0105 | 0.0226 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0174 | 0.0105 | 0.5 |
Onchocerca volvulus | 0.0174 | 0.0105 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0174 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.3274 | 0.3407 | 0.3407 |
Brugia malayi | Peptidase family M1 containing protein | 0.0174 | 0.0105 | 0.0076 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0102 | 0.0028 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0174 | 0.0105 | 0.0076 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0174 | 0.0105 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0174 | 0.0105 | 0.5 |
Brugia malayi | hypothetical protein | 0.0174 | 0.0105 | 0.0076 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0028 | 0.0028 |
Brugia malayi | TATA binding protein associated factor | 0.0174 | 0.0105 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0105 | 0.0105 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0174 | 0.0105 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.3274 | 0.3407 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0174 | 0.0105 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0174 | 0.0105 | 0.0226 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0174 | 0.0105 | 0.5 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0174 | 0.0105 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0028 | 0.0028 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0174 | 0.0105 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0105 | 0.0105 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0174 | 0.0105 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0174 | 0.0105 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0174 | 0.0105 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0002 | 0.0002 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0174 | 0.0105 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0174 | 0.0105 | 0.5 |
Toxoplasma gondii | aminopeptidase N protein | 0.0174 | 0.0105 | 1 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0174 | 0.0105 | 0.5 |
Loa Loa (eye worm) | aminopeptidase N | 0.0174 | 0.0105 | 0.0105 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0174 | 0.0105 | 0.5 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.9463 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.