Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | peptidase family M13 protein | 0.0097 | 0.0049 | 1 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.5189 | 1 | 1 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0097 | 0.0049 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1696 | 0.3174 | 1 |
Brugia malayi | hypothetical protein | 0.078 | 0.1384 | 0.1352 |
Trypanosoma cruzi | aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1696 | 0.3174 | 0.3174 |
Loa Loa (eye worm) | aminopeptidase N | 0.009 | 0.0036 | 0.0036 |
Trypanosoma brucei | aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0003 | 0.0003 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0097 | 0.0049 | 0.5 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.009 | 0.0036 | 0.5 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0097 | 0.0049 | 0.0042 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0097 | 0.0049 | 0.0013 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.009 | 0.0036 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.009 | 0.0036 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.009 | 0.0036 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.009 | 0.0036 | 0.5 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0097 | 0.0049 | 0.0042 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.009 | 0.0036 | 0.5 |
Brugia malayi | Peptidase family M13 containing protein | 0.0097 | 0.0049 | 0.0013 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.009 | 0.0036 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.009 | 0.0036 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.009 | 0.0036 | 0.5 |
Onchocerca volvulus | 0.009 | 0.0036 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0003 | 0.0003 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.009 | 0.0036 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.009 | 0.0036 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.009 | 0.0036 | 0.5 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.1696 | 0.3174 | 1 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.009 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0097 | 0.0049 | 1 |
Onchocerca volvulus | 0.009 | 0.0036 | 0.5 | |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.009 | 0.0036 | 0.0036 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.009 | 0.0036 | 0.5 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0097 | 0.0049 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0049 | 0.0049 |
Trypanosoma cruzi | aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0049 | 0.0049 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.009 | 0.0036 | 0.0036 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.009 | 0.0036 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.009 | 0.0036 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.009 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0036 | 0.0036 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1696 | 0.3174 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0036 | 0.0036 |
Entamoeba histolytica | aminopeptidase, putative | 0.009 | 0.0036 | 0.5 |
Onchocerca volvulus | 0.009 | 0.0036 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.