TDR Targets

Basic information

Technical information

TDR Targets ID: 872548
Name: N-[(3-fluorophenyl)methyl]-1-[6-(4-methoxyphe nyl)imidazo[1,2-d][1,3,4]thiadiazol-2-yl]pipe ridine-4-carboxamide
MW: 465.543 | Formula: C24H24FN5O2S
H donors: 1 H acceptors: 3 LogP: 4.3 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1)c1cn2c(n1)sc(n2)N1CCC(CC1)C(=O)NCc1cccc(c1)F
InChi: 1S/C24H24FN5O2S/c1-32-20-7-5-17(6-8-20)21-15-30-23(27-21)33-24(28-30)29-11-9-18(10-12-29)22(31)26-14-16-3-2-4-19(25)13-16/h2-8,13,15,18H,9-12,14H2,1H3,(H,26,31)
InChiKey: KRNHUAUKRJDYML-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

N-[(3-fluorophenyl)methyl]-1-[6-(4-methoxyphenyl)-2-imidazo[1,2-d][1,3,4]thiadiazolyl]-4-piperidinecarboxamide
N-(3-fluorobenzyl)-1-[6-(4-methoxyphenyl)imidazo[1,2-d][1,3,4]thiadiazol-2-yl]isonipecotamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus		0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Brugia malayi	cathepsin Z-like cysteine proteinase	0.012	0.0599	0.0599
Giardia lamblia	Hypothetical protein	0.012	0.0599	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Onchocerca volvulus		0.0648	1	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0648	1	1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0277	0.3399	0.2978
Trypanosoma cruzi	cysteine proteinase, putative	0.0334	0.441	0.4054
Toxoplasma gondii	cathepsin CPL	0.0648	1	1
Giardia lamblia	Cysteine protease	0.012	0.0599	0.5
Loa Loa (eye worm)	hypothetical protein	0.0434	0.6189	0.6189
Echinococcus multilocularis	cathepsin L cysteine protease	0.0648	1	1
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0648	1	1
Giardia lamblia	Hypothetical protein	0.012	0.0599	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0334	0.441	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Giardia lamblia	Cathepsin L precursor	0.012	0.0599	0.5
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Leishmania major	cathepsin L-like protease	0.0648	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0296	0.3746	0.3746
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Giardia lamblia	Cathepsin L-like protease	0.012	0.0599	0.5
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0214	0.2283	0.1791
Trypanosoma cruzi	cysteine peptidase, putative	0.0648	1	1
Echinococcus multilocularis	cysteine protease	0.0648	1	1
Brugia malayi	Cathepsin L-like precursor	0.0648	1	1
Brugia malayi	cathepsin F-like cysteine proteinase	0.0214	0.2283	0.2283
Giardia lamblia	Cysteine protease	0.012	0.0599	0.5
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0434	0.6189	0.6189
Echinococcus multilocularis	cathepsin L	0.012	0.0599	0.0599
Loa Loa (eye worm)	ctsf protein	0.0648	1	1
Giardia lamblia	Cysteine protease	0.012	0.0599	0.5
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0334	0.441	0.4054
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2283	0.2283
Schistosoma mansoni	voltage-gated potassium channel	0.0324	0.423	0.423
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0648	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0648	1	1
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.012	0.0599	0.5
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Plasmodium vivax	vivapain-2	0.0648	1	1
Leishmania major	cathepsin L-like protease	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Loa Loa (eye worm)	cysteine protease	0.0648	1	1
Leishmania major	cathepsin L-like protease	0.0648	1	1
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.012	0.0599	0.0599
Leishmania major	cathepsin L-like protease	0.0648	1	1
Leishmania major	cathepsin L-like protease	0.0648	1	1
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Schistosoma mansoni	cathepsin F (C01 family)	0.0434	0.6189	0.6189
Brugia malayi	Cathepsin L-like precursor	0.0648	1	1
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0296	0.3746	0.3746
Schistosoma mansoni	cathepsin C	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine protease, putative	0.0648	1	1
Brugia malayi	cathepsin L-like precursor	0.0434	0.6189	0.6189
Onchocerca volvulus		0.0648	1	1
Entamoeba histolytica	cysteine proteinase 2	0.0334	0.441	0.4054
Trypanosoma cruzi	cysteine protease, putative	0.0334	0.441	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Brugia malayi	Cathepsin L-like precursor	0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0214	0.2283	0.2283
Entamoeba histolytica	cysteine proteinase 1, putative	0.0334	0.441	0.4054
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0434	0.6189	0.5946
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Onchocerca volvulus	Cathepsin L homolog	0.0648	1	1
Echinococcus granulosus	cathepsin L cysteine protease	0.0334	0.441	0.441
Entamoeba histolytica	cysteine proteinase, putative	0.0334	0.441	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0434	0.6189	0.5946
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Brugia malayi	cathepsin L-like cysteine proteinase	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Echinococcus multilocularis	cathepsin b	0.012	0.0599	0.0599
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0648	1	1
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0277	0.3399	0.2978
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0296	0.3746	0.3746
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0334	0.441	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0434	0.6189	0.5946
Trypanosoma cruzi	cysteine peptidase, putative	0.0648	1	1
Echinococcus granulosus	cathepsin b	0.012	0.0599	0.0599
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0648	1	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0648	1	1
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.012	0.0599	0.0599
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0434	0.6189	0.6189
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.012	0.0599	0.0599
Onchocerca volvulus	Cathepsin F homolog	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Onchocerca volvulus		0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Brugia malayi	Cathepsin L-like precursor	0.0434	0.6189	0.6189
Brugia malayi	Papain family cysteine protease containing protein	0.0334	0.441	0.441
Brugia malayi	cathepsin Z-like cysteine proteinase	0.012	0.0599	0.0599
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Brugia malayi	Papain family cysteine protease containing protein	0.012	0.0599	0.0599
Loa Loa (eye worm)	hypothetical protein	0.0257	0.3049	0.3049
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.012	0.0599	0.0599
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Leishmania major	cathepsin L-like protease	0.0648	1	1
Onchocerca volvulus		0.0434	0.6189	0.5946
Loa Loa (eye worm)	hypothetical protein	0.0434	0.6189	0.6189
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Loa Loa (eye worm)	fibroinase	0.0648	1	1
Brugia malayi	cathepsin L precursor	0.012	0.0599	0.0599
Loa Loa (eye worm)	hypothetical protein	0.0214	0.2283	0.2283
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Brugia malayi	Papain family cysteine protease containing protein	0.0334	0.441	0.441
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Plasmodium vivax	vivapain-3	0.0334	0.441	0.4054
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0334	0.441	0.441
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Onchocerca volvulus		0.0648	1	1
Onchocerca volvulus		0.0648	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0648	1	1
Leishmania major	cathepsin L-like protease	0.0648	1	1
Plasmodium vivax	vivapain-1	0.0334	0.441	0.4054
Giardia lamblia	Cathepsin L-like protease	0.012	0.0599	0.5
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0648	1	1
Giardia lamblia	Cathepsin L precursor	0.012	0.0599	0.5
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine proteinase, putative	0.0334	0.441	0.4054
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0648	1	1
Plasmodium vivax	vivapain-2	0.0648	1	1
Plasmodium vivax	unspecified product	0.0214	0.2283	0.1791
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0648	1	1
Giardia lamblia	Cathepsin B-like cysteine proteinase 3 precursor	0.012	0.0599	0.5
Trypanosoma cruzi	cysteine peptidase, putative	0.0334	0.441	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Loa Loa (eye worm)	hypothetical protein	0.0648	1	1
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0648	1	1
Brugia malayi	cathepsin B-like cysteine proteinase	0.012	0.0599	0.0599
Brugia malayi	Papain family cysteine protease containing protein	0.012	0.0599	0.0599
Schistosoma mansoni	voltage-gated potassium channel	0.0324	0.423	0.423
Schistosoma mansoni	cathepsin s	0.0214	0.2283	0.2283
Trypanosoma cruzi	cruzipain precursor, putative	0.0214	0.2283	0.1791
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0334	0.441	0.4054
Echinococcus multilocularis	cysteine protease	0.0648	1	1
Echinococcus granulosus	cathepsin l1	0.0434	0.6189	0.6189
Leishmania major	cysteine peptidase A (CPA)	0.0648	1	1
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.012	0.0599	0.5
Leishmania major	cathepsin L-like protease	0.0648	1	1
Giardia lamblia	Cathepsin B precursor	0.012	0.0599	0.5
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Brugia malayi	Papain family cysteine protease containing protein	0.012	0.0599	0.0599
Onchocerca volvulus		0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Echinococcus multilocularis	cathepsin b	0.012	0.0599	0.0599
Echinococcus multilocularis	cathepsin L cysteine protease	0.0648	1	1
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0296	0.3746	0.3746
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0648	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.012	0.0599	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Brugia malayi	Cathepsin L-like precursor	0.0434	0.6189	0.6189
Loa Loa (eye worm)	hypothetical protein	0.0214	0.2283	0.2283
Giardia lamblia	Cathepsin L precursor	0.012	0.0599	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Brugia malayi	Cathepsin L-like precursor	0.0648	1	1
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.012	0.0599	0.0599
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0214	0.2283	0.2283
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Brugia malayi	Papain family cysteine protease containing protein	0.0648	1	1
Giardia lamblia	Cathepsin L precursor	0.012	0.0599	0.5
Trypanosoma cruzi	cysteine proteinase, putative	0.0334	0.441	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Brugia malayi	Cathepsin L-like precursor	0.0648	1	1
Giardia lamblia	Encystation-specific protease	0.012	0.0599	0.5
Echinococcus multilocularis	cathepsin L	0.0334	0.441	0.441
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Echinococcus granulosus	cysteine protease	0.0334	0.441	0.441
Entamoeba histolytica	cysteine proteinase, putative	0.0334	0.441	0.4054
Brugia malayi	cathepsin F-like cysteine proteinase	0.012	0.0599	0.0599
Schistosoma mansoni	cathepsin S (C01 family)	0.012	0.0599	0.0599
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0334	0.441	0.4054
Entamoeba histolytica	cysteine proteinase, putative	0.0648	1	1
Giardia lamblia	Cathepsin L precursor	0.012	0.0599	0.5
Schistosoma mansoni	cathepsin B (C01 family)	0.012	0.0599	0.0599
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0648	1	1
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.012	0.0599	0.0599
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0648	1	1
Loa Loa (eye worm)	hypothetical protein	0.0214	0.2283	0.2283
Plasmodium vivax	unspecified product	0.0334	0.441	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0648	1	1
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.012	0.0599	0.0599
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0334	0.441	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Onchocerca volvulus	Cathepsin L homolog	0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Giardia lamblia	Cathepsin L precursor	0.012	0.0599	0.5
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0334	0.441	0.441
Echinococcus granulosus	cathepsin L	0.0334	0.441	0.441
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0334	0.441	0.441
Entamoeba histolytica	cysteine proteinase, putative	0.0334	0.441	0.4054
Loa Loa (eye worm)	hypothetical protein	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Giardia lamblia	Cysteine protease	0.012	0.0599	0.5
Echinococcus granulosus	cathepsin L	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Loa Loa (eye worm)	cathepsin B	0.012	0.0599	0.0599
Entamoeba histolytica	cysteine proteinase, putative	0.0648	1	1
Entamoeba histolytica	cysteine protease, putative	0.0334	0.441	0.4054
Echinococcus granulosus	cathepsin l1	0.0648	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.012	0.0599	0.0599
Echinococcus granulosus	cathepsin b	0.012	0.0599	0.0599
Brugia malayi	fibroinase precursor	0.012	0.0599	0.0599
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0434	0.6189	0.5946
Trypanosoma cruzi	cruzipain precursor, putative	0.0648	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0648	1	1
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.012	0.0599	0.0599

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 872548