TDR Targets

Basic information

Technical information

TDR Targets ID: 872634
Name: 1-[6-(4-methylphenyl)imidazo[1,2-d][1,3,4]thi adiazol-2-yl]-N-propan-2-ylpiperidine-3-carbo xamide
MW: 383.51 | Formula: C20H25N5OS
H donors: 1 H acceptors: 3 LogP: 3.9 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: CC(NC(=O)C1CCCN(C1)c1nn2c(s1)nc(c2)c1ccc(cc1)C)C
InChi: 1S/C20H25N5OS/c1-13(2)21-18(26)16-5-4-10-24(11-16)20-23-25-12-17(22-19(25)27-20)15-8-6-14(3)7-9-15/h6-9,12-13,16H,4-5,10-11H2,1-3H3,(H,21,26)
InChiKey: LDNOJULYZIMGCZ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-isopropyl-1-[6-(4-methylphenyl)imidazo[1,2-d][1,3,4]thiadiazol-2-yl]piperidine-3-carboxamide
N-isopropyl-1-[6-(4-methylphenyl)-2-imidazo[1,2-d][1,3,4]thiadiazolyl]-3-piperidinecarboxamide
N-isopropyl-1-[6-(4-methylphenyl)imidazo[1,2-d][1,3,4]thiadiazol-2-yl]nipecotamide
1-[6-(4-methylphenyl)imidazo[1,2-d][1,3,4]thiadiazol-2-yl]-N-propan-2-yl-piperidine-3-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	Aminopeptidase M1, putative	0.023	0.0469	1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0061	0.0076	0.1258
Leishmania major	protein kinase A regulatory subunit, putative	0.0041	0.0029	0.0611
Leishmania major	hypothetical protein, conserved	0.0041	0.0029	0.0611
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0061	0.0076	0.0048
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.009	0.0143	0.0114
Echinococcus multilocularis	voltage gated potassium channel	0.009	0.0143	0.0114
Treponema pallidum	catabolite gene activator	0.0041	0.0029	0.5
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0076	0.0076
Brugia malayi	Calcitonin receptor-like protein seb-1	0.006	0.0074	0.0162
Mycobacterium tuberculosis	Probable glutamine-transport ATP-binding protein ABC transporter GlnQ	0.0041	0.0029	1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.029	0.0607	1
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.023	0.0469	0.7716
Leishmania major	hypothetical protein, conserved	0.0041	0.0029	0.0611
Mycobacterium ulcerans	hypothetical protein	0.0041	0.0029	0.0611
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.031	0.0655	0.1435
Brugia malayi	Peptidase family M1 containing protein	0.023	0.0469	0.1027
Leishmania major	hypothetical protein, unknown function	0.0041	0.0029	0.0611
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.023	0.0469	1
Brugia malayi	Egg laying defective protein 4	0.0041	0.0029	0.0064
Loa Loa (eye worm)	hypothetical protein	0.023	0.0469	0.0468
Chlamydia trachomatis	cAMP-dependent protein kinase regulatory subunit	0.0041	0.0029	0.5
Onchocerca volvulus		0.023	0.0469	1
Trichomonas vaginalis	cAMP-dependent protein kinase regulatory subunit, putative	0.0041	0.0029	0.0477
Echinococcus granulosus	cAMP dependent protein kinase type II regulatory	0.0041	0.0029	0.0029
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.0061	0.0076	0.0048
Echinococcus granulosus	microtubule associated protein 2	0.0833	0.1872	0.1872
Loa Loa (eye worm)	MH2 domain-containing protein	0.0144	0.0269	0.0269
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.0061	0.0076	0.0048
Onchocerca volvulus		0.0041	0.0029	0.0611
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.023	0.0469	1
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.023	0.0469	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0029	0.0029
Mycobacterium tuberculosis	Probable transcriptional regulatory protein Cmr	0.0041	0.0029	1
Schistosoma mansoni	similar to Protein C20orf152 homolog	0.0041	0.0029	0.0029
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0061	0.0076	0.0076
Loa Loa (eye worm)	hypothetical protein	0.009	0.0143	0.0142
Entamoeba histolytica	hypothetical protein	0.0043	0.0035	0.0736
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0041	0.0029	0.0029
Schistosoma mansoni	hypothetical protein	0.0043	0.0035	0.0035
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.023	0.0469	0.0469
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.023	0.0469	0.0441
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0061	0.0076	0.0076
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0061	0.0076	0.0076
Brugia malayi	AMP-binding enzyme family protein	0.0029	0	0.0001
Entamoeba histolytica	hypothetical protein	0.0043	0.0035	0.0736
Leishmania major	cyclic nucleotide-binding protein-like protein	0.0041	0.0029	0.0611
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.023	0.0469	0.7716
Leishmania major	protein kinase, putative	0.0041	0.0029	0.0611
Treponema pallidum	catabolite gene activator (Crp)	0.0041	0.0029	0.5
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.023	0.0469	0.0469
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.023	0.0469	0.0469
Loa Loa (eye worm)	transcription factor SMAD2	0.0144	0.0269	0.0269
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0041	0.0029	0.0477
Mycobacterium ulcerans	aminopeptidase N PepN	0.023	0.0469	1
Brugia malayi	AMP-binding enzyme family protein	0.0029	0	0.0001
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0061	0.0076	0.0076
Loa Loa (eye worm)	cAMP-dependent protein kinase regulatory subunit	0.0041	0.0029	0.0029
Trypanosoma cruzi	aminopeptidase, putative	0.023	0.0469	1
Leishmania major	hypothetical protein, conserved	0.0041	0.0029	0.0611
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.023	0.0469	0.0469
Trypanosoma cruzi	aminopeptidase, putative	0.023	0.0469	1
Trichomonas vaginalis	cAMP-dependent protein kinase type I-beta regulatory subunit, putative	0.0041	0.0029	0.0477
Loa Loa (eye worm)	peptidase family M1 containing protein	0.023	0.0469	0.0468
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0029	0.0029
Mycobacterium leprae	Conserved hypothetical protein	0.0041	0.0029	1
Trypanosoma brucei	cAMP response protein 1, putative	0.0041	0.0029	0.0618
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.023	0.0469	0.0441
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.023	0.0469	1
Schistosoma mansoni	camp-dependent protein kinase type I-beta regulatory subunit	0.0041	0.0029	0.0029
Schistosoma mansoni	camp-dependent protein kinase type II-alpha regulatory subunit	0.0041	0.0029	0.0029
Schistosoma mansoni	voltage-gated potassium channel	0.009	0.0143	0.0143
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.006	0.0074	0.0162
Brugia malayi	hypothetical protein	0.023	0.0469	0.1027
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.031	0.0655	0.0628
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.023	0.0469	1
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.031	0.0655	0.0655
Brugia malayi	Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog	0.0041	0.0029	0.0064
Echinococcus granulosus	aminopeptidase N	0.023	0.0469	0.0469
Trypanosoma brucei	protein kinase A regulatory subunit	0.0041	0.0029	0.0618
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0041	0.0029	0.0029
Brugia malayi	TATA binding protein associated factor	0.023	0.0469	0.1027
Brugia malayi	cAMP-dependent protein kinase regulatory chain, putative	0.0041	0.0029	0.0064
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0041	0.0029	0.0611
Toxoplasma gondii	aminopeptidase N protein	0.023	0.0469	1
Schistosoma mansoni	camp-dependent protein kinase type I-beta regulatory subunit	0.0041	0.0029	0.0029
Loa Loa (eye worm)	TATA binding protein associated factor	0.023	0.0469	0.0468
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0061	0.0076	0.0076
Entamoeba histolytica	hypothetical protein	0.0043	0.0035	0.0736
Leishmania major	protein kinase, putative	0.0041	0.0029	0.0611
Schistosoma mansoni	voltage-gated potassium channel	0.0338	0.0721	0.0721
Loa Loa (eye worm)	aminopeptidase N	0.023	0.0469	0.0468
Plasmodium falciparum	M1-family alanyl aminopeptidase, putative	0.023	0.0469	1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0061	0.0076	0.1258
Entamoeba histolytica	hypothetical protein	0.0043	0.0035	0.0736
Echinococcus multilocularis	Peptidase M1, membrane alanine aminopeptidase, N terminal	0.023	0.0469	0.0441
Loa Loa (eye worm)	hypothetical protein	0.023	0.0469	0.0468
Leishmania major	regulatory subunit of protein kinase a-like protein	0.0041	0.0029	0.0611
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0029	0	0.0126
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.023	0.0469	1
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.023	0.0469	0.0469
Schistosoma mansoni	transcription factor LCR-F1	0.0043	0.0035	0.0035
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0029	0	0.0126
Treponema pallidum	cyclic nucleotide binding protein	0.0041	0.0029	0.5
Loa Loa (eye worm)	hypothetical protein	0.006	0.0074	0.0073
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.009	0.0143	0.0143
Brugia malayi	N-terminal motif family protein	0.0041	0.0029	0.0064
Schistosoma mansoni	camp-dependent rap1 guanine-nucleotide exchange factor	0.0041	0.0029	0.0029
Mycobacterium ulcerans	aminopeptidase N PepN	0.023	0.0469	1
Schistosoma mansoni	serine/threonine protein kinase	0.0041	0.0029	0.0029
Schistosoma mansoni	serine/threonine protein kinase	0.0041	0.0029	0.0029
Treponema pallidum	cyclic nucleotide binding protein	0.0041	0.0029	0.5
Schistosoma mansoni	Tata binding protein associated factor (M01 family)	0.023	0.0469	0.0469
Leishmania major	puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.023	0.0469	1
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.023	0.0469	0.0469
Brugia malayi	MH2 domain containing protein	0.0144	0.0269	0.059
Brugia malayi	hypothetical protein	0.0043	0.0035	0.0076
Brugia malayi	AMP-binding enzyme family protein	0.0029	0	0.0001
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0061	0.0076	0.0048
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.023	0.0469	0.0441
Mycobacterium ulcerans	hypothetical protein	0.0041	0.0029	0.0611
Mycobacterium ulcerans	transcriptional regulatory protein	0.0041	0.0029	0.0611
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.4328	1	1
Giardia lamblia	CAMP-dependent protein kinase regulatory chain	0.0041	0.0029	0.5
Mycobacterium tuberculosis	Probable conserved transmembrane transport protein	0.0041	0.0029	1
Mycobacterium ulcerans	transmembrane transport protein	0.0041	0.0029	0.0611
Trypanosoma cruzi	metallo-peptidase, Clan MA(E) Family M1	0.023	0.0469	1
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0061	0.0076	0.0076
Trypanosoma brucei	cyclic nucleotide-binding domain containing protein, putative	0.0041	0.0029	0.0618
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0041	0.0029	1
Schistosoma mansoni	microtubule-associated protein tau	0.0833	0.1872	0.1872
Echinococcus granulosus	hyperpolarization activated cyclic	0.0061	0.0076	0.0076
Trypanosoma brucei	Flagellar Member 6	0.0041	0.0029	0.0618
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.006	0.0074	0.0073
Trypanosoma brucei	Aminopeptidase M1, putative	0.023	0.0469	1
Loa Loa (eye worm)	hypothetical protein	0.023	0.0469	0.0468
Onchocerca volvulus		0.023	0.0469	1
Trypanosoma brucei	cyclic nucleotide-binding domain containing protein, putative	0.0041	0.0029	0.0618
Onchocerca volvulus		0.023	0.0469	1
Trypanosoma brucei	cAMP binding protein, putative	0.0041	0.0029	0.0618
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.023	0.0469	0.0469
Schistosoma mansoni	voltage-gated potassium channel	0.009	0.0143	0.0143
Schistosoma mansoni	neuropathy target esterase/swiss cheese-related protein	0.0041	0.0029	0.0029
Echinococcus granulosus	cGMP dependent protein kinase	0.0041	0.0029	0.0029
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0041	0.0029	1
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.009	0.0143	0.0313
Echinococcus granulosus	cAMP dependent protein kinase regulatory	0.0041	0.0029	0.0029
Trypanosoma cruzi	Aminopeptidase M1, putative	0.023	0.0469	1
Toxoplasma gondii	aminopeptidase n, putative	0.023	0.0469	1
Brugia malayi	hypothetical protein	0.023	0.0469	0.1027
Schistosoma mansoni	voltage-gated potassium channel	0.0049	0.0047	0.0047
Onchocerca volvulus		0.0041	0.0029	0.0611
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0029	0.0029
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.023	0.0469	0.0441
Schistosoma mansoni	cytosol alanyl aminopeptidase (M01 family)	0.023	0.0469	0.0469
Echinococcus granulosus	cAMP dependent protein kinase type I beta	0.0041	0.0029	0.0029
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0061	0.0076	0.0168
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.023	0.0469	0.7716
Schistosoma mansoni	hypothetical protein	0.0041	0.0029	0.0029
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.0061	0.0076	0.0076
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0041	0.0029	0.0029
Schistosoma mansoni	cyclic nucleotide-gated ion channel	0.0041	0.0029	0.0029
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.023	0.0469	1
Mycobacterium ulcerans	hypothetical protein	0.0041	0.0029	0.0611
Echinococcus granulosus	voltage gated potassium channel	0.009	0.0143	0.0143
Schistosoma mansoni	voltage-gated potassium channel	0.0338	0.0721	0.0721
Schistosoma mansoni	serine/threonine protein kinase	0.0041	0.0029	0.0029
Schistosoma mansoni	voltage-gated potassium channel	0.0061	0.0076	0.0076
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0041	0.0029	0.0477
Loa Loa (eye worm)	hypothetical protein	0.0269	0.056	0.0559
Schistosoma mansoni	hypothetical protein	0.0041	0.0029	0.0029
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0043	0.0035	0.0006
Echinococcus multilocularis	microtubule associated protein 2	0.0833	0.1872	0.1848
Entamoeba histolytica	aminopeptidase, putative	0.023	0.0469	1
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0029	0.0477
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0061	0.0076	0.0076
Mycobacterium tuberculosis	Conserved protein	0.0041	0.0029	1
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0043	0.0035	0.0035
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.4328	1	1
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.023	0.0469	1
Schistosoma mansoni	camp-dependent protein kinase regulatory chain	0.0041	0.0029	0.0029
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.029	0.0607	1
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.0061	0.0076	0.0048
Brugia malayi	latrophilin 2 splice variant baaae	0.0041	0.0029	0.0065
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.4328	1	1
Echinococcus granulosus	hyperpolarization activated cyclic	0.0061	0.0076	0.0076
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0061	0.0076	0.0076
Brugia malayi	Peptidase family M1 containing protein	0.023	0.0469	0.1027
Schistosoma mansoni	camp-dependent protein kinase type II regulatory subunit	0.0041	0.0029	0.0029
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.031	0.0655	0.0654
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.023	0.0469	1
Schistosoma mansoni	aminopeptidase A (M01 family)	0.023	0.0469	0.0469
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0061	0.0076	0.0076
Mycobacterium tuberculosis	Probable conserved transmembrane protein	0.0041	0.0029	1
Echinococcus granulosus	patatin phospholipase domain containing protein	0.0041	0.0029	0.0029
Loa Loa (eye worm)	AGC/PKG protein kinase	0.0041	0.0029	0.0029
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0041	0.0029	0.0029
Brugia malayi	Peptidase family M1 containing protein	0.023	0.0469	0.1027
Mycobacterium ulcerans	regulatory protein	0.0041	0.0029	0.0611
Brugia malayi	hypothetical protein	0.199	0.4562	1
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.023	0.0469	1
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0041	0.0029	0.0029
Schistosoma mansoni	60S ribosomal protein L21	0.0049	0.0047	0.0047
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.023	0.0469	1
Brugia malayi	Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative	0.0041	0.0029	0.0064
Schistosoma mansoni	neuropathy target esterase/swiss cheese-related protein	0.0041	0.0029	0.0029
Mycobacterium ulcerans	hypothetical protein	0.0041	0.0029	0.0611
Plasmodium falciparum	M1-family alanyl aminopeptidase	0.023	0.0469	1
Toxoplasma gondii	aminopeptidase N, putative	0.023	0.0469	1
Echinococcus multilocularis	aminopeptidase N	0.023	0.0469	0.0441
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.0061	0.0076	0.0076
Trypanosoma brucei	aminopeptidase, putative	0.023	0.0469	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 872634