Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0035 | 0.0122 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0163 | 0.0168 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0075 | 0.0401 | 0.2116 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.04 | 0.2113 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0035 | 0.0127 | 0.0627 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.0793 |
Schistosoma mansoni | nuclear hormone receptor | 0.0035 | 0.0127 | 0.0627 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0115 | 0.0682 | 0.3618 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0039 | 0.0156 | 0.016 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0046 | 0.0202 | 1 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0035 | 0.0122 | 0.5737 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0075 | 0.0401 | 0.2116 |
Echinococcus multilocularis | RUN | 0.0041 | 0.0163 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0244 | 0.0251 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0052 | 0.0244 | 0.3026 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Brugia malayi | AMP-binding enzyme family protein | 0.0052 | 0.0244 | 0.0251 |
Brugia malayi | Isocitrate dehydrogenase | 0.0019 | 0.0011 | 0.0011 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0075 | 0.0401 | 0.0301 |
Trichomonas vaginalis | hypothetical protein | 0.0064 | 0.0323 | 0.167 |
Schistosoma mansoni | rab6-interacting | 0.0041 | 0.0163 | 0.0827 |
Brugia malayi | nuclear receptor NHR-88 | 0.0075 | 0.0401 | 0.0412 |
Onchocerca volvulus | 0.0041 | 0.0163 | 0.0062 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0075 | 0.0401 | 0.0412 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0039 | 0.0152 | 0.1859 |
Schistosoma mansoni | coup transcription factor | 0.0075 | 0.0401 | 0.2116 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Schistosoma mansoni | polycystin 1-related | 0.0041 | 0.0163 | 0.0827 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0075 | 0.0401 | 0.2116 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0052 | 0.0244 | 0.16 |
Loa Loa (eye worm) | thymidylate synthase | 0.0113 | 0.0667 | 0.0685 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0052 | 0.0244 | 0.16 |
Brugia malayi | thymidylate synthase | 0.0113 | 0.0667 | 0.0685 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0152 | 0.0157 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0128 | 0.0771 | 0.1168 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0075 | 0.0401 | 0.0412 |
Brugia malayi | nuclear hormone receptor | 0.0075 | 0.0401 | 0.0412 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 0.0771 | 0.4105 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0075 | 0.0401 | 0.2116 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0075 | 0.0401 | 0.0599 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0052 | 0.0244 | 0.1242 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.1418 | 0.9726 | 1 |
Onchocerca volvulus | 0.0035 | 0.0127 | 0.0024 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Brugia malayi | RNA binding protein | 0.0075 | 0.04 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0166 | 0.1035 | 0.5558 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0041 | 0.0163 | 0.0234 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0102 | 0.0105 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0035 | 0.0127 | 0.013 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0128 | 0.0771 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0075 | 0.0401 | 0.2116 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0035 | 0.0127 | 0.0177 |
Schistosoma mansoni | rab6-interacting | 0.0041 | 0.0163 | 0.0827 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0052 | 0.0244 | 0.1242 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0015 | 0.0022 |
Schistosoma mansoni | nuclear hormone receptor | 0.0035 | 0.0127 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus granulosus | tar DNA binding protein | 0.0075 | 0.04 | 0.2113 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0113 | 0.0667 | 0.8012 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0052 | 0.0244 | 0.16 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0152 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0163 | 0.0168 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0075 | 0.0401 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 0.0771 | 0.4105 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0054 | 0.0255 | 0.1677 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0037 | 0.0138 | 0.1665 |
Brugia malayi | phosphofructokinase | 0.0128 | 0.0771 | 0.0793 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0075 | 0.0401 | 0.0412 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0171 | 0.1068 | 0.5739 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Onchocerca volvulus | 0.0041 | 0.0163 | 0.0062 | |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0102 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0075 | 0.0401 | 0.2116 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0205 | 0.1032 |
Schistosoma mansoni | lipoxygenase | 0.017 | 0.1059 | 0.5692 |
Brugia malayi | Dihydrofolate reductase | 0.0115 | 0.0682 | 0.0701 |
Echinococcus granulosus | lamin | 0.0032 | 0.0102 | 0.0496 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0115 | 0.0682 | 0.1031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0075 | 0.0401 | 0.0412 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.005 | 0.0231 | 0.1189 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0075 | 0.0401 | 0.0412 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0075 | 0.0401 | 0.0412 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0075 | 0.0401 | 0.0412 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0115 | 0.0682 | 0.0701 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0228 | 0.1467 | 0.7883 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0052 | 0.0244 | 0.1242 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0015 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0152 | 0.0157 |
Brugia malayi | nuclear receptor RXR | 0.0035 | 0.0127 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0163 | 0.0827 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0052 | 0.0244 | 0.3064 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.035 | 0.2329 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0015 | 0.0022 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0015 | 0.0028 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0039 | 0.0152 | 0.0971 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0041 | 0.0163 | 0.0827 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0035 | 0.0127 | 0.0627 |
Mycobacterium ulcerans | thymidylate synthase | 0.0113 | 0.0667 | 0.3536 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0075 | 0.0401 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0039 | 0.0152 | 0.0971 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0035 | 0.0127 | 0.013 |
Loa Loa (eye worm) | TAR-binding protein | 0.0075 | 0.04 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.005 | 0.0231 | 0.1169 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus granulosus | FTZ F1 alpha | 0.0075 | 0.0401 | 0.2116 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0035 | 0.0127 | 0.0024 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0015 | 0.0028 |
Brugia malayi | nuclear receptor RXR | 0.0039 | 0.0156 | 0.016 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0015 | 0.0006 |
Mycobacterium ulcerans | ketopantoate reductase, ApbA | 0.0284 | 0.1857 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0956 | 0.6518 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0041 | 0.0163 | 0.1046 |
Loa Loa (eye worm) | doublecortin family protein | 0.0041 | 0.0163 | 0.0168 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0054 | 0.0255 | 0.1302 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0035 | 0.0127 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0046 | 0.0202 | 0.2464 |
Brugia malayi | isocitrate dehydrogenase | 0.0019 | 0.0011 | 0.0011 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0041 | 0.0163 | 0.0234 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0052 | 0.0244 | 0.3064 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0075 | 0.0401 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Brugia malayi | tailless protein | 0.0035 | 0.0127 | 0.013 |
Onchocerca volvulus | 0.0075 | 0.0401 | 0.0301 | |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0113 | 0.0667 | 0.8621 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0102 | 0.0105 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0035 | 0.0127 | 0.013 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0171 | 0.1068 | 0.1624 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0035 | 0.0127 | 0.013 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0075 | 0.0401 | 0.0599 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0075 | 0.0401 | 0.0412 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0015 | 0.0054 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0046 | 0.0202 | 0.1309 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0153 | 0.077 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0075 | 0.0401 | 0.0599 |
Brugia malayi | TAR-binding protein | 0.0075 | 0.04 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0163 | 0.0168 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0039 | 0.0156 | 0.016 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0075 | 0.0401 | 0.0412 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0115 | 0.0682 | 0.8301 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0128 | 0.0771 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0075 | 0.04 | 0.0411 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0035 | 0.0127 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.035 | 0.2329 |
Schistosoma mansoni | dihydrofolate reductase | 0.0115 | 0.0682 | 0.3642 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0035 | 0.0127 | 0.013 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0128 | 0.0771 | 0.4128 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0.0127 | 0.0177 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0115 | 0.0682 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.035 | 0.0521 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0075 | 0.0401 | 0.0412 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0075 | 0.0401 | 0.2116 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0075 | 0.04 | 0.0411 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0054 | 0.0255 | 0.321 |
Mycobacterium ulcerans | hypothetical protein | 0.0052 | 0.0244 | 0.1242 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0128 | 0.0771 | 0.5224 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0035 | 0.0127 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Mycobacterium ulcerans | 2-dehydropantoate 2-reductase | 0.011 | 0.0646 | 0.3426 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0052 | 0.0244 | 0.1242 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0075 | 0.0401 | 0.2116 |
Brugia malayi | dihydrofolate reductase family protein | 0.0115 | 0.0682 | 0.0701 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0228 | 0.1467 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0052 | 0.0244 | 0.0251 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0128 | 0.0771 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.035 | 0.2329 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0039 | 0.0152 | 0.0745 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0015 | 0.0016 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0052 | 0.0244 | 0.3026 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0102 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Onchocerca volvulus | 0.0052 | 0.0244 | 0.0143 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0035 | 0.0127 | 0.013 |
Brugia malayi | steroid hormone receptor | 0.0075 | 0.0401 | 0.0412 |
Echinococcus multilocularis | tar DNA binding protein | 0.0075 | 0.04 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0098 | 0.0101 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0041 | 0.0163 | 0.0234 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0128 | 0.0771 | 0.5224 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0035 | 0.0127 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0075 | 0.0401 | 0.0412 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0039 | 0.0156 | 0.0787 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.04 | 0.2113 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 0.0771 | 0.4105 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.005 | 0.0231 | 0.1189 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0075 | 0.0401 | 0.0599 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0035 | 0.0127 | 0.0627 |
Brugia malayi | Doublecortin family protein | 0.0041 | 0.0163 | 0.0168 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0035 | 0.0122 | 0.1414 |
Brugia malayi | ecdysone receptor | 0.0035 | 0.0127 | 0.013 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0255 | 0.0262 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0035 | 0.0127 | 0.0177 |
Echinococcus granulosus | dihydrofolate reductase | 0.0115 | 0.0682 | 0.3642 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0284 | 0.1853 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0075 | 0.0401 | 0.0412 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0075 | 0.0401 | 0.0599 |
Schistosoma mansoni | zinc finger protein | 0.0035 | 0.0127 | 0.0627 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0075 | 0.0401 | 0.0412 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.04 | 0.2113 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0075 | 0.0401 | 0.2116 |
Brugia malayi | nuclear receptor NHR-67 | 0.0035 | 0.0127 | 0.013 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0075 | 0.0401 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0075 | 0.0401 | 0.2116 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0035 | 0.0122 | 0.0763 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0067 | 0.035 | 0.4428 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0228 | 0.1467 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0039 | 0.0156 | 0.0223 |
Onchocerca volvulus | 0.0035 | 0.0127 | 0.0024 | |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0228 | 0.1467 | 1 |
Echinococcus multilocularis | lamin | 0.0032 | 0.0102 | 0.014 |
Loa Loa (eye worm) | DR-78 | 0.0035 | 0.0127 | 0.013 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0015 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0075 | 0.0401 | 0.2116 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0035 | 0.0127 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0244 | 0.0251 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.04 | 0.2113 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0035 | 0.0127 | 0.0627 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0015 | 0.0028 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0035 | 0.0127 | 0.0024 |
Loa Loa (eye worm) | phosphofructokinase | 0.0128 | 0.0771 | 0.0793 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0075 | 0.0401 | 0.2116 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0075 | 0.0401 | 0.2116 |
Echinococcus multilocularis | thymidylate synthase | 0.0113 | 0.0667 | 0.1007 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0035 | 0.0127 | 0.0177 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0019 | 0.0011 | 0.0011 |
Brugia malayi | nuclear hormone receptor | 0.1418 | 0.9726 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0052 | 0.0244 | 0.1242 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0075 | 0.0401 | 0.0412 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0128 | 0.0771 | 1 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0163 | 0.0168 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0035 | 0.0122 | 0.0763 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0052 | 0.0244 | 0.3026 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0052 | 0.0244 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.4105 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0244 | 0.0251 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0102 | 0.0105 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0075 | 0.0401 | 0.0412 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0067 | 0.035 | 0.2329 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0015 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0075 | 0.0401 | 0.0412 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0015 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Schistosoma mansoni | lamin | 0.0032 | 0.0102 | 0.0496 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 0.0771 | 0.4105 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.035 | 0.036 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0075 | 0.0401 | 0.0412 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0035 | 0.0127 | 0.0627 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0037 | 0.0138 | 0.1665 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0401 | 0.0412 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0075 | 0.0401 | 0.2116 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0035 | 0.0127 | 0.013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0284 | 0.1857 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0035 | 0.0127 | 0.0627 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0075 | 0.0401 | 0.0599 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0035 | 0.0122 | 0.0601 |
Brugia malayi | AMP-binding enzyme family protein | 0.0052 | 0.0244 | 0.0251 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0075 | 0.0401 | 0.0301 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0037 | 0.0138 | 0.1665 |
Schistosoma mansoni | thyroid hormone receptor | 0.0075 | 0.0401 | 0.2116 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0228 | 0.1467 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0052 | 0.0244 | 0.1242 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0075 | 0.0401 | 0.0412 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0102 | 0.014 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0039 | 0.0156 | 0.0787 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0075 | 0.0401 | 0.2116 |
Schistosoma mansoni | thyroid hormone receptor | 0.0075 | 0.0401 | 0.2116 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.005 | 0.0231 | 0.1508 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.005 | 0.0231 | 0.1192 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0015 | 0.0016 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0284 | 0.1853 | 0.283 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0102 | 0.0105 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0284 | 0.1853 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.0793 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.035 | 0.1841 |
Loa Loa (eye worm) | acetyltransferase | 0.0171 | 0.1068 | 0.1098 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0075 | 0.0401 | 0.0599 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0041 | 0.0163 | 0.0827 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0113 | 0.0667 | 0.3559 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0037 | 0.0138 | 0.1665 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0075 | 0.0401 | 0.2116 |
Brugia malayi | ecdysteroid receptor | 0.0075 | 0.0401 | 0.0412 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0041 | 0.0163 | 0.1046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0075 | 0.0401 | 0.0412 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0039 | 0.0156 | 0.0787 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0015 | 0.0022 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0171 | 0.1068 | 0.1098 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0128 | 0.0771 | 1 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0035 | 0.0122 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0102 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0152 | 0.0157 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0243 | 0.1566 | 0.8444 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0035 | 0.0127 | 0.0627 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0243 | 0.1566 | 0.239 |
Brugia malayi | conserved hypotetical protein | 0.0035 | 0.0127 | 0.013 |
Echinococcus granulosus | thymidylate synthase | 0.0113 | 0.0667 | 0.3559 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0075 | 0.0401 | 0.0599 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0228 | 0.1467 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0075 | 0.0401 | 0.2116 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0153 | 0.0218 |
Toxoplasma gondii | 3-methyl-2-oxobutanoate hydroxymethyltransferase | 0.0284 | 0.1857 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0128 | 0.0771 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0075 | 0.0401 | 0.2116 |
Loa Loa (eye worm) | hypothetical protein | 0.1382 | 0.9481 | 0.9748 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0102 | 0.0105 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0115 | 0.0682 | 0.8822 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0075 | 0.0401 | 0.0412 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.0793 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0102 | 0.0496 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0284 | 0.1857 | 1 |
Schistosoma mansoni | lamin | 0.0032 | 0.0102 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0152 | 0.0157 |
Schistosoma mansoni | loxhd1 | 0.0041 | 0.0163 | 0.0827 |
Echinococcus granulosus | RUN | 0.0041 | 0.0163 | 0.0827 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0156 | 0.016 |
Schistosoma mansoni | lipoxygenase | 0.0243 | 0.1566 | 0.8444 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0075 | 0.0401 | 0.0412 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0067 | 0.035 | 0.036 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.4128 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.035 | 0.1841 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0035 | 0.0122 | 0.058 |
Schistosoma mansoni | nuclear receptor | 0.0035 | 0.0127 | 0.0627 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0041 | 0.0163 | 0.0827 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0035 | 0.0127 | 0.0627 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0015 | 0.0022 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0039 | 0.0152 | 0.0542 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0128 | 0.0771 | 0.5224 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.011 | 0.0646 | 0.8355 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0075 | 0.04 | 0.0411 |
Brugia malayi | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.0793 |
Schistosoma mansoni | tar DNA-binding protein | 0.0075 | 0.04 | 0.2113 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0039 | 0.0156 | 0.016 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0035 | 0.0122 | 0.0601 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0128 | 0.0771 | 0.4128 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0.0127 | 0.0627 |
Onchocerca volvulus | 0.0113 | 0.0667 | 0.057 | |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.005 | 0.0231 | 0.1169 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0035 | 0.0122 | 0.0601 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0035 | 0.0122 | 0.1414 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.