Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.3985 | 0.3985 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0649 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 1 | 1 |
Plasmodium falciparum | citrate synthase, mitochondrial, putative | 0.0038 | 0.1511 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0062 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0649 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.5389 | 0.5389 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.3985 | 0.3985 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0649 | 0.0649 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.5389 | 0.5389 |
Toxoplasma gondii | citrate synthase I | 0.0038 | 0.1511 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.3985 | 0.3985 |
Trypanosoma cruzi | citrate synthase, putative | 0.0038 | 0.1511 | 0.5 |
Leishmania major | citrate synthase, putative | 0.0038 | 0.1511 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 1 | 1 |
Brugia malayi | Probable citrate synthase, mitochondrial precursor, putative | 0.0038 | 0.1511 | 0.1511 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.3985 | 0.3985 |
Plasmodium vivax | citrate synthase, mitochondrial precursor, putative | 0.0038 | 0.1511 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0649 | 0.0649 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Leishmania major | citrate synthase, putative | 0.0038 | 0.1511 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.5389 | 0.5389 |
Loa Loa (eye worm) | citrate synthase | 0.0038 | 0.1511 | 0.1511 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.3985 | 0.3568 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.3985 | 0.3568 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0038 | 0.1511 | 0.5 |
Echinococcus multilocularis | citrate synthase | 0.0038 | 0.1511 | 0.0922 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.3985 | 0.3985 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.5389 | 0.5389 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Echinococcus granulosus | citrate synthase | 0.0038 | 0.1511 | 0.0922 |
Trypanosoma brucei | citrate synthase, putative | 0.0038 | 0.1511 | 0.5 |
Plasmodium vivax | unspecified product | 0.0038 | 0.1511 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0649 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Trypanosoma cruzi | citrate synthase, putative | 0.0038 | 0.1511 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0649 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.3985 | 0.3568 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0649 | 0.0649 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.3985 | 0.3568 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.