Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.3255 | 0.3255 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0127 | 0.3015 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.3255 | 0.3255 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0437 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0436 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0436 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0436 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0838 | 0.0838 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0436 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0381 | 0.0381 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0838 | 0.0838 |
Onchocerca volvulus | 0.0037 | 0.0437 | 1 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0436 | 0.0436 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0437 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0437 | 0.5 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0436 | 0.0436 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0437 | 0.0437 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0436 | 0.134 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0838 | 0.2576 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0437 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.3255 | 0.3255 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0437 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0437 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0437 | 0.5 |
Leishmania major | protein kinase, putative,serine/threonine protein kinase, putative | 0.0127 | 0.3015 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0437 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0136 | 0.3255 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0437 | 0.1343 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0381 | 0.0381 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0437 | 0.1343 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0843 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0437 | 0.0437 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0436 | 0.134 |
Brugia malayi | TAR-binding protein | 0.0136 | 0.3255 | 0.3255 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0437 | 0.0437 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0437 | 0.0437 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0437 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0843 | 0.0843 |
Loa Loa (eye worm) | RNA binding protein | 0.0136 | 0.3255 | 0.3255 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0437 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0838 | 0.2576 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0437 | 0.0437 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0437 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0136 | 0.3255 | 0.3255 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0843 | 0.0843 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.0372 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0136 | 0.3255 | 1 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0437 | 0.0437 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0236 | 0.6121 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0437 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.3255 | 0.3255 |
Loa Loa (eye worm) | TAR-binding protein | 0.0136 | 0.3255 | 0.3255 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0437 | 0.0437 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0127 | 0.3015 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0437 | 0.0437 |
Onchocerca volvulus | 0.0037 | 0.0437 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0437 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0381 | 0.0381 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0437 | 0.5 |
Trypanosoma brucei | wee1-like protein kinase | 0.0127 | 0.3015 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0436 | 0.0436 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0136 | 0.3255 | 0.3255 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0838 | 0.0838 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0838 | 0.0838 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0838 | 0.0838 |
Brugia malayi | RNA binding protein | 0.0136 | 0.3255 | 0.3255 |
Onchocerca volvulus | 0.0037 | 0.0437 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.3255 | 0.3255 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0437 | 0.0437 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0127 | 0.3015 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0843 | 0.0843 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0838 | 0.2576 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0437 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0372 | 1 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0437 | 0.5 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0437 | 0.0437 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0838 | 0.2576 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0127 | 0.3015 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.