Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0216 | 0.002 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.028 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.4068 | 0.2804 | 0.2804 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0216 | 0.002 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0216 | 0.002 | 0.0043 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | aminopeptidase N | 0.0216 | 0.002 | 0.002 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.0072 | 0.0072 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0379 | 0.0138 | 0.0485 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0216 | 0.002 | 0.0064 |
Trypanosoma brucei | aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0216 | 0.002 | 0.002 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0379 | 0.0138 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.002 | 0.002 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0379 | 0.0138 | 0.0118 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0379 | 0.0138 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.4068 | 0.2804 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0216 | 0.002 | 0.5 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0216 | 0.002 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.0072 | 0.0072 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0216 | 0.002 | 0.0064 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0216 | 0.002 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0216 | 0.002 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0216 | 0.002 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Toxoplasma gondii | peptidase family M13 protein | 0.0379 | 0.0138 | 1 |
Onchocerca volvulus | 0.0216 | 0.002 | 1 | |
Onchocerca volvulus | 0.0216 | 0.002 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0379 | 0.0138 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.002 | 0.002 |
Entamoeba histolytica | aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0216 | 0.002 | 0.0043 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0216 | 0.002 | 0.5 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0379 | 0.0138 | 0.5 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0216 | 0.002 | 0.0064 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.0072 | 0.0072 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.028 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0216 | 0.002 | 1 | |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0379 | 0.0138 | 0.0465 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0216 | 0.002 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0379 | 0.0138 | 0.0138 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0379 | 0.0138 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.0072 | 0.0072 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0067 | 0.0067 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.4068 | 0.2804 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0067 | 0.0067 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0216 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 1.4027 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.187 | 0.1216 | 0.1198 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0216 | 0.002 | 0.5 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.4068 | 0.2804 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0216 | 0.002 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0216 | 0.002 | 0.0043 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0379 | 0.0138 | 0.0465 |
Brugia malayi | Peptidase family M13 containing protein | 0.0379 | 0.0138 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.002 | 0.002 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0216 | 0.002 | 0.002 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0216 | 0.002 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.