Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.003 | 0.0038 | 0.0054 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0052 | 0.0092 | 0.4361 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.011 | 0.01 |
Trypanosoma cruzi | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.1145 | 0.2738 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0015 | 0.0042 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0052 | 0.0092 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.014 | 0.0198 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0091 | 0.0186 | 0.0265 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.011 | 0.0822 |
Onchocerca volvulus | 0.0028 | 0.0034 | 0.0215 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0015 | 0.0042 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0031 | 0.0044 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0027 | 0.0063 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0096 | 0.0199 | 0.2752 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0038 | 0.0102 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.028 | 0.0644 | 0.5216 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0154 | 0.0339 | 0.0483 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0301 | 0.0696 | 0.0686 |
Brugia malayi | hypothetical protein | 0.0018 | 0.001 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0038 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.014 | 0.0198 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0096 | 0.0199 | 0.2752 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0034 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0043 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0028 | 0.0032 | 0.1505 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0267 | 0.2117 |
Brugia malayi | hypothetical protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | CHE-14 protein | 0.0129 | 0.0279 | 0.0397 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.001 | 0.0014 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0127 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0027 | 0.0038 |
Echinococcus multilocularis | tumor protein p63 | 0.0328 | 0.0759 | 0.075 |
Brugia malayi | Patched protein homolog 1 | 0.0018 | 0.001 | 0.0014 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.052 | 0.1224 | 0.9991 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.001 | 0.0037 |
Brugia malayi | hypothetical protein | 0.0229 | 0.0521 | 0.0742 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0015 | 0.0042 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0015 | 0.0042 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0032 | 0.1474 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0028 | 0.0034 | 0.05 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0015 | 0.0022 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.052 | 0.1224 | 0.1215 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0306 | 0.0707 | 0.5734 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0096 | 0.0199 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0015 | 0.0022 |
Trypanosoma cruzi | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.1145 | 0.2738 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.028 | 0.0644 | 0.0916 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.0144 | 0.0204 |
Schistosoma mansoni | topbp1 | 0.003 | 0.0038 | 0.0229 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | topoisomerase | 0.003 | 0.0038 | 0.0054 |
Loa Loa (eye worm) | carboxylesterase | 0.0067 | 0.0127 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0028 | 0.0034 | 0.0048 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0105 | 0.0221 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0028 | 0.0034 | 0.021 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0025 | 0.0025 | 0.0797 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0031 | 0.0043 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0015 | 0.0042 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0144 | 0.1099 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.0087 |
Schistosoma mansoni | hypothetical protein | 0.052 | 0.1225 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0038 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0068 | 0.013 | 0.6366 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0015 | 0.0022 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0015 | 0.0005 |
Trichomonas vaginalis | set domain proteins, putative | 0.0485 | 0.1139 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.011 | 0.5297 |
Brugia malayi | hypothetical protein | 0.011 | 0.0232 | 0.0331 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0084 | 0.0604 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0015 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0038 | 0.0247 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0144 | 0.1182 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0044 | 0.0062 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0028 | 0.0034 | 0.1257 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0301 | 0.0696 | 0.5641 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0221 | 0.0314 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0034 | 0.0087 |
Echinococcus granulosus | expressed conserved protein | 0.0283 | 0.0651 | 0.5276 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0049 | 0.0084 | 0.0119 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0015 | 0.005 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0431 | 0.1009 | 0.822 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0084 | 0.0604 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0015 | 0.0042 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0015 | 0.0042 |
Brugia malayi | AMP-binding enzyme family protein | 0.0096 | 0.0199 | 0.0283 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0015 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0036 | 0.023 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0027 | 0.0063 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0028 | 0.0034 | 0.1257 |
Echinococcus granulosus | GPCR family 2 | 0.0049 | 0.0084 | 0.0604 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0052 | 0.0092 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Echinococcus granulosus | geminin | 0.052 | 0.1225 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0096 | 0.0199 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.0087 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0015 | 0.0005 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0028 | 0.0032 | 0.04 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0015 | 0.0042 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0091 | 0.0186 | 0.0265 |
Onchocerca volvulus | 0.0088 | 0.0178 | 0.1492 | |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0232 | 0.3239 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0229 | 0.0521 | 0.0511 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0027 | 0.118 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0127 | 0.0181 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.003 | 0.0038 | 0.1478 |
Echinococcus granulosus | tumor protein p63 | 0.0328 | 0.0759 | 0.6166 |
Echinococcus multilocularis | geminin | 0.052 | 0.1225 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0199 | 0.0282 |
Schistosoma mansoni | patched 1 | 0.0129 | 0.0279 | 0.221 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0028 | 0.0034 | 0.1621 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0015 | 0.0042 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0073 | 0.0556 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0267 | 0.2117 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0127 | 0.0181 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Brugia malayi | AMP-binding enzyme family protein | 0.0096 | 0.0199 | 0.0283 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.003 | 0.0038 | 0.074 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.001 | 0.0015 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0052 | 0.0092 | 0.4361 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.001 | 0.0013 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0065 | 0.0093 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0031 | 0.0021 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0079 | 0.0112 |
Giardia lamblia | Replication factor C, subunit 1 | 0.003 | 0.0038 | 0.1582 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0072 | 0.014 | 0.8699 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0028 | 0.0034 | 0.0346 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0015 | 0.005 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.003 | 0.0038 | 0.19 |
Echinococcus multilocularis | protein dispatched 1 | 0.0148 | 0.0323 | 0.0313 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0084 | 0.0073 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0113 | 0.0103 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0015 | 0.0021 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0015 | 0.0005 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.003 | 0.0038 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Brugia malayi | putative malonyl-CoA decarboxylase | 0.2914 | 0.7023 | 1 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.003 | 0.0038 | 0.0247 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0015 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.001 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.0159 | 0.1227 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0028 | 0.0034 | 0.1257 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0091 | 0.0186 | 0.0646 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0005 | 0.0008 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0034 | 0.0087 |
Entamoeba histolytica | hypothetical protein | 0.003 | 0.0038 | 0.0407 |
Brugia malayi | Patched related family protein 4 | 0.0018 | 0.001 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Onchocerca volvulus | 0.0048 | 0.0082 | 0.0637 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.028 | 0.0644 | 0.5216 |
Brugia malayi | protein C24B5.3 | 0.0018 | 0.001 | 0.0014 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0028 | 0.0034 | 0.0195 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0028 | 0.0034 | 0.1257 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0127 | 0.0117 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0049 | 0.0084 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0015 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0015 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0113 | 0.0849 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0091 | 0.0186 | 0.145 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0034 | 0.0048 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0127 | 0.0964 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.011 | 0.5297 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.0113 | 0.0849 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0015 | 0.0022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.028 | 0.0644 | 0.5216 |
Onchocerca volvulus | 0.0047 | 0.0079 | 0.0611 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0031 | 0.0043 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.1621 |
Chlamydia trachomatis | DNA ligase | 0.003 | 0.0038 | 0.0959 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0015 | 0.0042 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0028 | 0.0034 | 0.1257 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0232 | 0.3239 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0015 | 0.0042 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0015 | 0.0022 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0 | 0.0001 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0431 | 0.1009 | 0.1 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.028 | 0.0644 | 0.5216 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.003 | 0.0038 | 0.0102 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0034 | 0.0087 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0065 | 0.0488 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0229 | 0.0521 | 0.4204 |
Brugia malayi | AMP-binding enzyme family protein | 0.0096 | 0.0199 | 0.0283 |
Toxoplasma gondii | propionate-CoA ligase | 0.0028 | 0.0034 | 0.1621 |
Echinococcus multilocularis | protein patched | 0.0129 | 0.0279 | 0.0269 |
Loa Loa (eye worm) | oxidoreductase | 0.0028 | 0.0034 | 0.0048 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0025 | 0.0025 | 0.1041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0129 | 0.0279 | 0.2378 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0038 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0028 | 0.0034 | 0.0048 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0015 | 0.0022 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0144 | 0.1182 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.003 | 0.0038 | 0.19 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0015 | 0.0005 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0015 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0065 | 0.0488 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0267 | 0.2117 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.028 | 0.0644 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0096 | 0.0199 | 0.0691 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0072 | 0.014 | 0.8548 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0015 | 0.0021 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.011 | 0.0822 |
Trypanosoma brucei | polo-like protein kinase | 0.0091 | 0.0186 | 0.0646 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.011 | 0.6715 |
Brugia malayi | hypothetical protein | 0.0018 | 0.001 | 0.0014 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0129 | 0.0279 | 0.221 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0024 | 0.0752 |
Echinococcus granulosus | carboxylesterase 5A | 0.0067 | 0.0127 | 0.0964 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0096 | 0.0199 | 0.0691 |
Onchocerca volvulus | 0.0032 | 0.0044 | 0.0302 | |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0113 | 0.693 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.0113 | 0.0103 |
Onchocerca volvulus | 0.0027 | 0.0031 | 0.0188 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0113 | 0.0849 |
Echinococcus multilocularis | GPCR, family 2 | 0.0049 | 0.0084 | 0.0073 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0144 | 0.0134 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0027 | 0.118 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0034 | 0.0087 |
Onchocerca volvulus | 0.0028 | 0.0034 | 0.0215 | |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.0032 | 0.1505 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0088 | 0.0178 | 0.1383 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 0.0213 |
Brugia malayi | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.0696 | 0.099 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0031 | 0.0021 |
Toxoplasma gondii | ATPase, AAA family protein | 0.003 | 0.0038 | 0.19 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0072 | 0.014 | 0.8699 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0025 | 0.0025 | 0.0797 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0091 | 0.0186 | 0.0646 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0031 | 0.0021 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0129 | 0.0279 | 0.221 |
Echinococcus granulosus | lamin | 0.0027 | 0.0031 | 0.017 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0084 | 0.0073 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0027 | 0.0039 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0034 | 0.1257 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0028 | 0.0034 | 0.1257 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 0.7903 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.014 | 0.0198 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0067 | 0.0127 | 0.0964 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0073 | 0.0556 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.0232 | 0.1827 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0154 | 0.0339 | 0.0482 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.1621 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0279 | 0.0396 |
Schistosoma mansoni | lamin | 0.0027 | 0.0031 | 0.017 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0221 | 0.1733 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0015 | 0.0022 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0015 | 0.0042 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0091 | 0.0186 | 0.0176 |
Onchocerca volvulus | 0.0028 | 0.0034 | 0.0215 | |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.003 | 0.0038 | 0.0247 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0038 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0301 | 0.0696 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.001 | 0.0037 |
Brugia malayi | protein C24B5.3 | 0.0018 | 0.001 | 0.0014 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.011 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0096 | 0.0199 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | kinase | 0.0046 | 0.0078 | 0.0556 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0113 | 0.0849 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.003 | 0.0038 | 0.0229 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0025 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0052 | 0.0092 | 0.3873 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0015 | 0.0022 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0065 | 0.0092 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0015 | 0.0042 |
Echinococcus multilocularis | expressed conserved protein | 0.0283 | 0.0651 | 0.0642 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0028 | 0.0034 | 0.05 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0015 | 0.0042 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0028 | 0.0034 | 0.0195 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0015 | 0.0022 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0018 | 0.001 | 0.0014 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.003 | 0.0038 | 0.0054 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0199 | 0.0282 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.028 | 0.0644 | 0.5216 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0129 | 0.0279 | 0.0269 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0065 | 0.0493 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0015 | 0.0042 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0068 | 0.013 | 0.6366 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0015 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0084 | 0.0604 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.003 | 0.0038 | 0.0028 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0049 | 0.0084 | 0.0119 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0031 | 0.0044 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0091 | 0.0186 | 0.2571 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0144 | 0.1099 |
Schistosoma mansoni | lamin | 0.0027 | 0.0031 | 0.017 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.003 | 0.0038 | 0.0102 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0096 | 0.0199 | 1 |
Wolbachia endosymbiont of Brugia malayi | malonyl-CoA decarboxylase | 0.2914 | 0.7023 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0015 | 0.0022 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0096 | 0.0199 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0096 | 0.0199 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0232 | 0.1827 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0015 | 0.0005 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.003 | 0.0038 | 0.0407 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0096 | 0.0199 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0091 | 0.0186 | 0.1565 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0031 | 0.017 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0015 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0015 | 0.0022 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0027 | 0.118 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0028 | 0.0034 | 0.05 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Brugia malayi | Pre-SET motif family protein | 0.0426 | 0.0997 | 0.1419 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0084 | 0.0604 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0096 | 0.0199 | 1 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0025 | 0.0025 | 0.0021 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0015 | 0.0005 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0028 | 0.0034 | 0.0048 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0034 | 0.0048 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0178 | 0.0253 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0144 | 0.0134 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0015 | 0.005 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0113 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0127 | 0.0181 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0091 | 0.0186 | 0.0646 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.0025 | 0.1041 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0027 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0084 | 0.0118 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0113 | 0.693 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0082 | 0.0116 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0028 | 0.0034 | 0.1621 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0088 | 0.0178 | 0.1383 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0025 | 0.0025 | 0.0055 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.0159 | 1 |
Onchocerca volvulus | 0.004 | 0.0063 | 0.047 | |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0096 | 0.0199 | 0.2752 |
Schistosoma mansoni | topbp1 | 0.003 | 0.0038 | 0.0229 |
Onchocerca volvulus | 0.0485 | 0.1139 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Brugia malayi | Patched related family protein 10 | 0.0018 | 0.001 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0084 | 0.0604 |
Leishmania major | malonyl-coa decarboxylase-like protein | 0.1145 | 0.2738 | 1 |
Echinococcus granulosus | nibrin | 0.003 | 0.0038 | 0.0229 |
Onchocerca volvulus | 0.0027 | 0.0031 | 0.0188 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.028 | 0.0644 | 0.0634 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0072 | 0.014 | 0.6871 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.011 | 0.5297 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0067 | 0.0127 | 0.0181 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0045 | 0.0075 | 0.0572 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0232 | 0.3239 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0032 | 0.1505 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0079 | 0.0564 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0028 | 0.0034 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0127 | 0.0181 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0301 | 0.0696 | 0.099 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0028 | 0.0034 | 0.1257 |
Brugia malayi | Myosin head containing protein | 0.0018 | 0.001 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0028 | 0.0034 | 0.1257 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0073 | 0.056 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0091 | 0.0186 | 0.145 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.003 | 0.0038 | 0.004 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.028 | 0.0644 | 0.0917 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0028 | 0.0034 | 0.0087 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0015 | 0.0021 |
Onchocerca volvulus | 0.0096 | 0.0199 | 0.1674 | |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0028 | 0.0034 | 0.0048 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.0232 | 0.0222 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0027 | 0.0063 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0015 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0028 | 0.0034 | 0.1257 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0027 | 0.118 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0199 | 0.0282 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.0159 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0073 | 0.0143 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.014 | 0.0198 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0088 | 0.0178 | 0.0254 |
Schistosoma mansoni | hypothetical protein | 0.052 | 0.1225 | 1 |
Onchocerca volvulus | 0.003 | 0.0038 | 0.0252 | |
Brugia malayi | Patched related family protein 12 | 0.0018 | 0.001 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0113 | 0.0161 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0015 | 0.0005 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0025 | 0.0025 | 0.0055 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.014 | 0.0198 |
Brugia malayi | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0015 | 0.0042 |
Brugia malayi | DKFZp564C0469 protein | 0.003 | 0.0038 | 0.0054 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.003 | 0.0038 | 0.0102 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0154 | 0.0339 | 0.0483 |
Giardia lamblia | Kinase, PLK | 0.0091 | 0.0186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0068 | 0.013 | 0.6366 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.011 | 0.0366 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.0144 | 0.0205 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0067 | 0.0127 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0034 | 0.0048 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.003 | 0.0042 |
Onchocerca volvulus | 0.0073 | 0.0143 | 0.1176 | |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0025 | 0.0025 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.0159 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.0349 | 0.0497 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.0025 | 0.1041 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0232 | 0.3239 |
Loa Loa (eye worm) | hypothetical protein | 0.2914 | 0.7023 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0068 | 0.013 | 0.6366 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0129 | 0.0279 | 0.0396 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0045 | 0.0075 | 0.0572 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0031 | 0.017 |
Trypanosoma brucei | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.1145 | 0.2738 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0079 | 0.0564 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0015 | 0.0042 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0144 | 0.1099 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.003 | 0.0038 | 0.0247 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0082 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Onchocerca volvulus | 0.0021 | 0.0015 | 0.005 | |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0028 | 0.0034 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0038 | 0.0054 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.001 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0096 | 0.0199 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0096 | 0.0199 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0096 | 0.0199 | 1 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0025 | 0.0025 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0159 | 0.0226 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0127 | 0.0964 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0108 | 0.0804 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0096 | 0.0199 | 0.0691 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0028 | 0.0034 | 0.1257 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.003 | 0.0038 | 0.19 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0025 | 0.0025 | 0.0797 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.0159 | 0.0227 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0015 | 0.0042 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0144 | 0.1099 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0015 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0034 | 0.0048 |
Treponema pallidum | DNA ligase (lig) | 0.003 | 0.0038 | 0.187 |
Echinococcus multilocularis | nibrin | 0.003 | 0.0038 | 0.0028 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0096 | 0.0199 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0028 | 0.0034 | 0.0024 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0034 | 0.0048 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0088 | 0.0178 | 0.0168 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0015 | 0.0005 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 0.7903 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.001 | 0.0037 |
Schistosoma mansoni | DNA ligase IV | 0.003 | 0.0038 | 0.0229 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0072 | 0.014 | 0.6871 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0015 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.0521 | 0.0741 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.003 | 0.0038 | 0.0247 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0186 | 0.1561 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0015 | 0.0021 |
Echinococcus granulosus | replication factor c subunit 1 | 0.003 | 0.0038 | 0.0229 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0038 | 0.0247 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.0159 | 0.1227 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.011 | 0.5297 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0015 | 0.0022 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.0232 | 0.1827 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0426 | 0.0997 | 0.1419 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0015 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0084 | 0.0604 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0267 | 0.2117 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.001 | 0.0013 |
Brugia malayi | Patched family protein | 0.0018 | 0.001 | 0.0014 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.001 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0015 | 0.0022 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0031 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.001 | 0.0013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0036 | 0.023 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.0159 | 0.7721 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.0339 | 0.0482 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0015 | 0.0022 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CD50 (functional) | > 100 uM | Cytotoxic dose required to reduce the proliferation of normal uninfected MT-4 cells by 50% | ChEMBL. | 9457243 |
CD50 (functional) | > 100 uM | Cytotoxic dose required to reduce the proliferation of normal uninfected MT-4 cells by 50% | ChEMBL. | 9457243 |
ED50 (functional) | = 21 uM | Effective dose required for 50% inhibition of HIV-1 antigen production in MT-4 cultures | ChEMBL. | 9457243 |
SI (functional) | > 5 | Selectivity index is the ratio between CD50 and IC50 values of the compound | ChEMBL. | 9457243 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.